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Protein Ontology report - integrin beta-1
PR:000002040 - http://purl.obolibrary.org/obo/PR_000002040
 
  Protein Forms  Complex  Annotations      
Ontology Information Show OBO stanza
  PRO ID
PR:000002040   
  PRO nameintegrin beta-1 
  Synonyms
PRO-Short-label: EXACT:ITGB1
Gene-based: RELATED:FNRB | MDF2 | MSK12
Other: EXACT:CD29 | fibronectin receptor subunit beta | VLA-4 subunit beta
  Definition"An integrin beta that is a translation product of the human ITGB1 gene or a 1:1 ortholog thereof." [PRO:WCB] 
  PRO Categorygene 
  ParentPR:000001861 integrin beta
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Gene1                                                  Organism-Gene 5                                        
         Sequence5                                                  Organism-Sequence 7                                        
         Modification1                                                  Organism-Modification 11                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Related Cross References

  Db identifiers
IUPHARobj:2455
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Protein Forms  Switch to Extended View   

Category  
PRO Form Name
Short Name
Ann. Has Annotation?

Comp. In Complex?
gene


PR:000002040 integrin beta-1
ITGB1

organism-gene


PR:P05556 integrin beta-1 (human)
hITGB1

organism-sequence


PR:P05556-1 integrin beta-1 isoform beta-1A (human)
hITGB1/iso:beta-1A

organism-sequence


PR:P05556-2 integrin beta-1 isoform beta-1B (human)
hITGB1/iso:beta-1B

organism-sequence


PR:P05556-3 integrin beta-1 isoform beta-1C (human)
hITGB1/iso:beta-1C

organism-sequence


PR:P05556-4 integrin beta-1 isoform beta-1C-2 (human)
hITGB1/iso:beta-1C-2

organism-sequence


PR:P05556-5 integrin beta-1 isoform beta-1D (human)
hITGB1/iso:beta-1D

organism-modification


PR:000028415 integrin beta-1, signal peptide removed form (human)
hITGB1/SigPep-

Yes
organism-modification


PR:000053565 integrin beta-1 N-glycosylated 1 (human)
hITGB1/NGlyco:1

organism-modification


PR:000053566 integrin beta-1 N-glycosylated 2 (human)
hITGB1/NGlyco:2

organism-modification


PR:000053567 integrin beta-1 N-glycosylated 3 (human)
hITGB1/NGlyco:3

organism-modification


PR:000053568 integrin beta-1 N-glycosylated 4 (human)
hITGB1/NGlyco:4

organism-modification


PR:000066244 integrin beta-1 deaminated 1 (human)
hITGB1/Deam:1

organism-modification


PR:000066932 integrin beta-1 methylated 1 (human)
hITGB1/Me:1

organism-modification


PR:000070391 integrin beta-1 cysteinylated 1 (human)
hITGB1/Cyst:1

organism-modification


PR:000072780 integrin beta-1 cysteinylated 2 (human)
hITGB1/Cyst:2

organism-modification


PR:000075713 integrin beta-1 cysteinylated 3 (human)
hITGB1/Cyst:3

organism-modification


PR:000083387 integrin beta-1 cysteinylated 4 (human)
hITGB1/Cyst:4

organism-gene


PR:P09055 integrin beta-1 (mouse)
mITGB1

organism-sequence


PR:P09055-1 integrin beta-1 isoform beta-1A (mouse)
mITGB1/iso:beta-1A
Yes
organism-sequence


PR:P09055-2 integrin beta-1 isoform beta-1D (mouse)
mITGB1/iso:beta-1D
Yes
organism-gene


PR:P11584 integrin beta-PS (fruit fly)
fly-ITGB1

organism-gene


PR:P49134 integrin beta-1 (rat)
rITGB1

organism-gene


PR:Q27874 integrin beta pat-3 (worm)
ITGB1 (worm)

sequence


PR:000037153 integrin beta-1 isoform beta-1A
ITGB1/iso:beta-1A

organism-sequence


PR:P05556-1 integrin beta-1 isoform beta-1A (human)
hITGB1/iso:beta-1A

organism-sequence


PR:P09055-1 integrin beta-1 isoform beta-1A (mouse)
mITGB1/iso:beta-1A
Yes
sequence


PR:000037155 integrin beta-1 isoform beta-1B
ITGB1/iso:beta-1B

organism-sequence


PR:P05556-2 integrin beta-1 isoform beta-1B (human)
hITGB1/iso:beta-1B

sequence


PR:000037157 integrin beta-1 isoform beta-1C
ITGB1/iso:beta-1C

organism-sequence


PR:P05556-3 integrin beta-1 isoform beta-1C (human)
hITGB1/iso:beta-1C

sequence


PR:000037159 integrin beta-1 isoform beta-1C-2
ITGB1/iso:beta-1C-2

organism-sequence


PR:P05556-4 integrin beta-1 isoform beta-1C-2 (human)
hITGB1/iso:beta-1C-2

sequence


PR:000037161 integrin beta-1 isoform beta-1D
ITGB1/iso:beta-1D

organism-sequence


PR:P05556-5 integrin beta-1 isoform beta-1D (human)
hITGB1/iso:beta-1D

organism-sequence


PR:P09055-2 integrin beta-1 isoform beta-1D (mouse)
mITGB1/iso:beta-1D
Yes
modification


PR:000018706 integrin beta-1, signal peptide removed form
ITGB1/SigPep-

organism-modification


PR:000028415 integrin beta-1, signal peptide removed form (human)
hITGB1/SigPep-

Yes
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ITGB1 forms found in complexes   

ITGB1 Component
 Complexes
PR:000028415 hITGB1/SigPep- PR:000028448 ILK:integrin beta-1 (human)
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Functional Annotation (PRO-centric view) Switch to GO Centric View   
PRO Term GO Annotation Evidence
PR:P09055-1 mITGB1/iso:beta-1A acts_upstream_of_or_withinGO:0016477 cell migration MGI_ref:1203253; PMID:9553049
PR:P09055-2 mITGB1/iso:beta-1D
This isoform contains a unique alternatively spliced cytoplasmic domain of 50 amino acids, with the last 24 amino acids encoded by an additional exon, 11 of these are in common with the isoform beta-1A		 acts_upstream_of_or_withinGO:0048738 cardiac muscle tissue development MGI_ref:1203253; PMID:9553049