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Protein Ontology report - interferon regulatory factor 8
PR:000002050 - http://purl.obolibrary.org/obo/PR_000002050
 
  Protein Forms  Annotations      
Ontology Information Show OBO stanza
  PRO ID
PR:000002050   
  PRO nameinterferon regulatory factor 8 
  Synonyms
PRO-Short-label: EXACT:IRF8
Gene-based: RELATED:ICSBP1
Other: EXACT:ICSBP | interferon consensus sequence-binding protein | IRF-8
  Definition"An interferon regulatory factor 3-9 that is a translation product of the human IRF8 gene or a 1:1 ortholog thereof." [PRO:WCB] 
  PRO Categorygene 
  ParentPR:000001863 interferon regulatory factor 3-9
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Gene1                                                  Organism-Gene 3                                        
         Sequence1                                                  Organism-Sequence 1                                        
         Modification2                                                  Organism-Modification 3                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Protein Forms  Switch to Extended View   

Category  
PRO Form Name
Short Name
Ann. Has Annotation?

Comp. In Complex?
gene


PR:000002050 interferon regulatory factor 8
IRF8

organism-gene


PR:P23611 interferon regulatory factor 8 (mouse)
mIRF8

organism-sequence


PR:P23611-1 interferon regulatory factor 8 isoform 1 (mouse)
mIRF8/iso:1

organism-modification


PR:000035707 interferon regulatory factor 8 isoform 1 sumoylated 1 (mouse)
mIRF8/iso:1/Sumo:1
Yes
organism-modification


PR:000035709 interferon regulatory factor 8 isoform 1 unsumoylated form (mouse)
mIRF8/iso:1/SumoRes-
Yes
organism-gene


PR:Q02556 interferon regulatory factor 8 (human)
hIRF8

organism-modification


PR:000067923 interferon regulatory factor 8 methylated 1 (human)
hIRF8/Me:1

organism-gene


PR:Q90871 interferon regulatory factor 8 (chicken)
chick-IRF8

sequence


PR:000035704 interferon regulatory factor 8 isoform 1
IRF8/iso:1

organism-sequence


PR:P23611-1 interferon regulatory factor 8 isoform 1 (mouse)
mIRF8/iso:1

organism-modification


PR:000035707 interferon regulatory factor 8 isoform 1 sumoylated 1 (mouse)
mIRF8/iso:1/Sumo:1
Yes
organism-modification


PR:000035709 interferon regulatory factor 8 isoform 1 unsumoylated form (mouse)
mIRF8/iso:1/SumoRes-
Yes
modification


PR:000035706 interferon regulatory factor 8 isoform 1 sumoylated 1
IRF8/iso:1/Sumo:1

organism-modification


PR:000035707 interferon regulatory factor 8 isoform 1 sumoylated 1 (mouse)
mIRF8/iso:1/Sumo:1
Yes
modification


PR:000035708 interferon regulatory factor 8 isoform 1 unsumoylated form
IRF8/iso:1/SumoRes-

organism-modification


PR:000035709 interferon regulatory factor 8 isoform 1 unsumoylated form (mouse)
mIRF8/iso:1/SumoRes-
Yes
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Functional Annotation (GO-centric view) Switch to PRO Centric View     

Biological Process GO Term
Protein Forms & Complexes
Evidence
GO:0060261 positive regulation of transcription initiation by RNA polymerase IIPR:000035709 mIRF8/iso:1/SumoRes- MGI_ref:5448615; PMID:22942423
NOT GO:0060261 positive regulation of transcription initiation by RNA polymerase IIPR:000035707 mIRF8/iso:1/Sumo:1 MGI_ref:5448615; PMID:22942423

Cellular Location GO Term
Protein Forms & Complexes
Evidence
GO:0005634 nucleusPR:000035707 mIRF8/iso:1/Sumo:1 MGI_ref:5448615; PMID:22942423
PR:000035709 mIRF8/iso:1/SumoRes- MGI_ref:5448615; PMID:22942423