|
|
 |
|
| | |
| | | | | | | |
gene
|
|
PR:000002190 |
RAC-alpha serine/threonine-protein kinase
|
AKT1
|
"An AKT kinase that is a translation product of the human AKT1 gene or a 1:1 ortholog thereof." [PRO:WCB]
|
|
|
|
|
|
|
| | | | |
| | | | | |
organism-gene
|
|
PR:P31749 |
RAC-alpha serine/threonine-protein kinase (human)
|
hAKT1
|
"A RAC-alpha serine/threonine-protein kinase that is encoded in the genome of human." [PRO:WCB, UniProtKB:P31749]
|
|
|
|
|
|
|
| | | | | | |
| | | |
organism-sequence
|
|
PR:000061890 |
RAC-alpha serine/threonine-protein kinase sequence variant E17K (human)
|
hAKT1/var:E17K
|
"A RAC-alpha serine/threonine-protein kinase (human) that has a Lys residue at the position equivalent to Glu-17 of the amino acid sequence represented by UniProtKB:P31749-1. Example: UniProtKB:P31749-1, Glu-17, CHEBI:29967." [PRO:DNx, Reactome:R-HSA-1500573, Reactome:R-HSA-2219526]
|
|
|
|
|
|
|
| | | | | | |
| | | |
organism-sequence
|
|
PR:P31749-1 |
RAC-alpha serine/threonine-protein kinase isoform 1 (human)
|
hAKT1/iso:1
|
"A RAC-alpha serine/threonine-protein kinase isoform 1 that is encoded in the genome of human." [PRO:JAN]
|
|
|
|
|
|
|
| | | | | | | | |
| |
organism-modification
|
|
PR:000027473 |
RAC-alpha serine/threonine-protein kinase isoform 1 phosphorylated 2 (human)
|
hAKT1/iso:1/Phos:2
|
"A RAC-alpha serine/threonine-protein kinase isoform 1 phosphorylated 2 in human. UniProtKB:P31749-1, Thr-72/Thr-308, MOD:00047|Ser-246/Ser-473, MOD:00046." [PMID:16549426, PRO:PD]
|
Yes |
|
|
|
|
|
| | | | | | | | |
| |
organism-modification
|
|
PR:000028994 |
RAC-alpha serine/threonine-protein kinase isoform 1 phosphorylated 1 (human)
|
hAKT1/iso:1/Phos:1
|
"A RAC-alpha serine/threonine-protein kinase isoform 1 phosphorylated 1 in human. UniProtKB:P31749-1, Thr-308, MOD:00047|Ser-473, MOD:00046." [PMID:8978681, PRO:ALI]
|
Yes |
|
|
|
|
|
| | | | | | |
| | | |
organism-sequence
|
|
PR:P31749-2 |
RAC-alpha serine/threonine-protein kinase isoform h2 (human)
|
hAKT1/iso:h2
|
"A RAC-alpha serine/threonine-protein kinase (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P31749-2." [PRO:DNx, UniProtKB:P31749]
|
|
|
|
|
|
|
| | | | | | |
| | | |
organism-modification
|
|
PR:000046294 |
RAC-alpha serine/threonine-protein kinase phosphorylated 3 (human)
|
hAKT1/Phos:3
|
"A RAC-alpha serine/threonine-protein kinase phosphorylated 3 in human. UniProtKB:P31749, Ser-473, MOD:00046." [PRO:CNA, PRO:DNx, Reactome:R-HSA-377265]
|
|
|
|
|
|
|
| | | | | | |
| | | |
organism-modification
|
|
PR:000046295 |
RAC-alpha serine/threonine-protein kinase phosphorylated 4 (human)
|
hAKT1/Phos:4
|
"A RAC-alpha serine/threonine-protein kinase (human) that has been phosphorylated on the residue at the position equivalent to Thr-308 of the amino acid sequence represented by UniProtKB:P31749. UniProtKB:P31749, Thr-308, MOD:00047." [PRO:DNx, Reactome:R-HSA-198634]
|
|
|
|
|
|
|
| | | | | | |
| | | |
organism-modification
|
|
PR:000046296 |
RAC-alpha serine/threonine-protein kinase phosphorylated 1 (human)
|
hAKT1/Phos:1
|
"A RAC-alpha serine/threonine-protein kinase (human) that has been phosphorylated on the residue at the position equivalent to Thr-308, and phosphoserine at position 473 of the amino acid sequence represented by UniProtKB:P31749. UniProtKB:P31749, Thr-308, MOD:00047|Ser-473, MOD:00046." [PRO:DNx, Reactome:R-HSA-198356, Reactome:R-HSA-198357, Reactome:R-HSA-199430]
|
|
|
|
|
|
|
| | | | | | |
| | | |
organism-modification
|
|
PR:000046297 |
RAC-alpha serine/threonine-protein kinase phosphorylated 5 (human)
|
hAKT1/Phos:5
|
"A RAC-alpha serine/threonine-protein kinase (human) that has been post-translationally modified to include phosphotyrosine at positions 315 and 326 of the amino acid sequence represented by UniProtKB:P31749. UniProtKB:P31749, Tyr-315/Tyr-326, MOD:00048." [PRO:DNx, Reactome:R-HSA-8848757]
|
|
|
|
|
|
|
| | | | | | |
| | | |
organism-modification
|
|
PR:000061529 |
RAC-alpha serine/threonine-protein kinase sequence variant E17K phosphorylated 1 (human)
|
hAKT1/var:E17K/Phos:1
|
"A RAC-alpha serine/threonine-protein kinase (human) that has a Lys residue at the position equivalent to Glu-17 of the amino acid sequence represented by UniProtKB:P31749-1 and that has been phosphorylated on the residue at the position equivalent to Ser-473. Example: UniProtKB:P31749-1, Glu-17, CHEBI:29967|Ser-473, MOD:00046." [PRO:DNx, Reactome:R-HSA-2243944]
|
|
|
|
|
|
|
| | | | | | |
| | | |
organism-modification
|
|
PR:000061599 |
RAC-alpha serine/threonine-protein kinase sequence variant E17K phosphorylated 2 (human)
|
hAKT1/var:E17K/Phos:2
|
"A RAC-alpha serine/threonine-protein kinase (human) that has a Lys residue at the position equivalent to Glu-17 of the amino acid sequence represented by UniProtKB:P31749-1 and that has been phosphorylated on the residues at the positions equivalent to Thr-308 and Ser-473. Example: UniProtKB:P31749-1, Glu-17, CHEBI:29967|Thr-308, MOD:00047|Ser-473, MOD:00046." [PRO:DNx, Reactome:R-HSA-2243935, Reactome:R-HSA-2399994]
|
|
|
|
|
|
|
| | | | | | |
| | | |
organism-modification
|
|
PR:000065619 |
RAC-alpha serine/threonine-protein kinase methylated 1 (human)
|
hAKT1/Me:1
|
"A RAC-alpha serine/threonine-protein kinase (human) that has been methylated on the residue at the position equivalent to Cys-60 of the amino acid sequence represented by UniProtKB:P31749-1. Example: UniProtKB:P31749-1, Cys-60, MOD:00660." [IEDB_epitope:1052366, PRO:DNx]
|
|
|
|
|
|
|
| | | | | | |
| | | |
organism-modification
|
|
PR:000068716 |
RAC-alpha serine/threonine-protein kinase phosphorylated 2 (human)
|
hAKT1/Phos:2
|
"A RAC-alpha serine/threonine-protein kinase (human) that has been phosphorylated on the residue at the position equivalent to Thr-371 of the amino acid sequence represented by UniProtKB:P31749-1. Example: UniProtKB:P31749-1, Thr-371, MOD:00047." [IEDB_epitope:2147736, PRO:DNx]
|
|
|
|
|
|
|
| | | | | | |
| | | |
organism-modification
|
|
PR:000072278 |
RAC-alpha serine/threonine-protein kinase deaminated 1 (human)
|
hAKT1/Deam:1
|
"A RAC-alpha serine/threonine-protein kinase (human) that has been deaminated on the residue at the position equivalent to Gln-59 of the amino acid sequence represented by UniProtKB:P31749-1. Example: UniProtKB:P31749-1, Gln-59, MOD:00685." [IEDB_epitope:931423, PRO:DNx]
|
|
|
|
|
|
|
| | | | |
| | | | | |
organism-gene
|
|
PR:P31750 |
RAC-alpha serine/threonine-protein kinase (mouse)
|
mAKT1
|
"A RAC-alpha serine/threonine-protein kinase that is encoded in the genome of mouse." [OMA:P31750, PRO:DNx]
|
|
|
|
|
|
|
| | | | | | |
| | | |
organism-sequence
|
|
PR:P31750-1 |
RAC-alpha serine/threonine-protein kinase isoform 1 (mouse)
|
mAKT1/iso:1
|
"A RAC-alpha serine/threonine-protein kinase isoform 1 that is encoded in the genome of mouse." [PRO:JAN]
|
|
|
|
|
|
|
| | | | | | |
| | | |
organism-modification
|
|
PR:000049940 |
RAC-alpha serine/threonine-protein kinase phosphorylated 3 (mouse)
|
mAKT1/Phos:3
|
"A RAC-alpha serine/threonine-protein kinase phosphorylated 3 in mouse. UniProtKB:P31750, Ser-473, MOD:00046." [PMID:27994061, PRO:LN]
|
|
|
|
|
|
|
| | | | | | |
| | | |
organism-modification
|
|
PR:000049942 |
RAC-alpha serine/threonine-protein kinase unphosphorylated 3 (mouse)
|
mAKT1/UnPhos:3
|
"A RAC-alpha serine/threonine-protein kinase unphosphorylated 3 in mouse. UniProtKB:P31750, Ser-473, PR:000026291." [PMID:27994061, PRO:LN]
|
|
|
|
|
|
|
| | | | | | |
| | | |
organism-modification
|
|
PR:000050596 |
RAC-alpha serine/threonine-protein kinase phosphorylated 1 (mouse)
|
mAKT1/Phos:1
|
"A RAC-alpha serine/threonine-protein kinase (mouse) that has been phosphorylated on the residue at the position equivalent to Thr-308, and phosphoserine at position 473 of the amino acid sequence represented by UniProtKB:P31750. UniProtKB:P31750, Thr-308, MOD:00047|Ser-473, MOD:00046." [PMID:31915252, PRO:LN]
|
|
|
|
|
|
|
| | | | |
| | | | | |
organism-gene
|
|
PR:P47196 |
RAC-alpha serine/threonine-protein kinase (rat)
|
rAKT1
|
"A RAC-alpha serine/threonine-protein kinase that is encoded in the genome of rat." [OMA:P47196, PRO:DNx]
|
|
|
|
|
|
|
| | | | |
| | | | | |
sequence
|
|
PR:000002286 |
RAC-alpha serine/threonine-protein kinase isoform 1
|
AKT1/iso:1
|
"A RAC-alpha serine/threonine-protein kinase that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P31749-1 or a 1:1 ortholog thereof." [PRO:JAN]
|
|
|
|
|
|
|
| | | | | | |
| | | |
organism-sequence
|
|
PR:P31749-1 |
RAC-alpha serine/threonine-protein kinase isoform 1 (human)
|
hAKT1/iso:1
|
"A RAC-alpha serine/threonine-protein kinase isoform 1 that is encoded in the genome of human." [PRO:JAN]
|
|
|
|
|
|
|
| | | | | | | | |
| |
organism-modification
|
|
PR:000027473 |
RAC-alpha serine/threonine-protein kinase isoform 1 phosphorylated 2 (human)
|
hAKT1/iso:1/Phos:2
|
"A RAC-alpha serine/threonine-protein kinase isoform 1 phosphorylated 2 in human. UniProtKB:P31749-1, Thr-72/Thr-308, MOD:00047|Ser-246/Ser-473, MOD:00046." [PMID:16549426, PRO:PD]
|
Yes |
|
|
|
|
|
| | | | | | | | |
| |
organism-modification
|
|
PR:000028994 |
RAC-alpha serine/threonine-protein kinase isoform 1 phosphorylated 1 (human)
|
hAKT1/iso:1/Phos:1
|
"A RAC-alpha serine/threonine-protein kinase isoform 1 phosphorylated 1 in human. UniProtKB:P31749-1, Thr-308, MOD:00047|Ser-473, MOD:00046." [PMID:8978681, PRO:ALI]
|
Yes |
|
|
|
|
|
| | | | | | |
| | | |
organism-sequence
|
|
PR:P31750-1 |
RAC-alpha serine/threonine-protein kinase isoform 1 (mouse)
|
mAKT1/iso:1
|
"A RAC-alpha serine/threonine-protein kinase isoform 1 that is encoded in the genome of mouse." [PRO:JAN]
|
|
|
|
|
|
|
| | | | | | |
| | | |
modification
|
|
PR:000003102 |
RAC-alpha serine/threonine-protein kinase isoform 1 phosphorylated form
|
AKT1/iso:1/PhosRes+
|
"A RAC-alpha serine/threonine-protein kinase isoform 1 that includes at least one phosphorylated residue." [PRO:CNA]
|
|
|
|
|
|
|
| | | | | | | | |
| |
modification
|
|
PR:000003103 |
RAC-alpha serine/threonine-protein kinase isoform 1 phosphorylated 1
|
AKT1/iso:1/Phos:1
|
"A RAC-alpha serine/threonine-protein kinase isoform 1 phosphorylated form that is an active kinase form. Example: UniProtKB:P31749-1, Thr-308, MOD:00047|Ser-473, MOD:00046." [PID:cd8tcrpathway, PID:pi3kciaktpathway, PID:ptp1bpathway, PID:tcrpathway, PMID:12586360, PRO:JAN]
|
|
|
|
|
|
|
| | | | | | | | | | |
organism-modification
|
|
PR:000028994 |
RAC-alpha serine/threonine-protein kinase isoform 1 phosphorylated 1 (human)
|
hAKT1/iso:1/Phos:1
|
"A RAC-alpha serine/threonine-protein kinase isoform 1 phosphorylated 1 in human. UniProtKB:P31749-1, Thr-308, MOD:00047|Ser-473, MOD:00046." [PMID:8978681, PRO:ALI]
|
Yes |
|
|
|
|
|
| | | | | | | | |
| |
modification
|
|
PR:000027472 |
RAC-alpha serine/threonine-protein kinase isoform 1 phosphorylated 2
|
AKT1/iso:1/Phos:2
|
"A RAC-alpha serine/threonine-protein kinase isoform 1 phosphorylated form that is the actived form (see PR:000003103), which has been further phosphorylated by autocatalysis in trans at two sites that lie in the characteristic AKT substrate motif RxRxx[ST]. Example: UniProtKB:P31749-1, Thr-72/Thr-308, MOD:00047|Ser-246/Ser-473, MOD:00046." [PMID:16549426, PRO:PD]
|
|
|
|
|
|
|
| | | | | | | | | | |
organism-modification
|
|
PR:000027473 |
RAC-alpha serine/threonine-protein kinase isoform 1 phosphorylated 2 (human)
|
hAKT1/iso:1/Phos:2
|
"A RAC-alpha serine/threonine-protein kinase isoform 1 phosphorylated 2 in human. UniProtKB:P31749-1, Thr-72/Thr-308, MOD:00047|Ser-246/Ser-473, MOD:00046." [PMID:16549426, PRO:PD]
|
Yes |
|
|
|
|
|
| | | | |
| | | | | |
modification
|
|
PR:000049939 |
RAC-alpha serine/threonine-protein kinase phosphorylated 3
|
AKT1/Phos:3
|
"A RAC-alpha serine/threonine-protein kinase that has been phosphorylated on the residue at the position equivalent to Ser-473 of the amino acid sequence represented by UniProtKB:P31749. Example: UniProtKB:P31749, Ser-473, MOD:00046." [PMID:27994061, PRO:LN, Reactome:R-HSA-377265]
|
|
|
|
|
|
|
| | | | | | |
| | | |
organism-modification
|
|
PR:000046294 |
RAC-alpha serine/threonine-protein kinase phosphorylated 3 (human)
|
hAKT1/Phos:3
|
"A RAC-alpha serine/threonine-protein kinase phosphorylated 3 in human. UniProtKB:P31749, Ser-473, MOD:00046." [PRO:CNA, PRO:DNx, Reactome:R-HSA-377265]
|
|
|
|
|
|
|
| | | | | | |
| | | |
organism-modification
|
|
PR:000049940 |
RAC-alpha serine/threonine-protein kinase phosphorylated 3 (mouse)
|
mAKT1/Phos:3
|
"A RAC-alpha serine/threonine-protein kinase phosphorylated 3 in mouse. UniProtKB:P31750, Ser-473, MOD:00046." [PMID:27994061, PRO:LN]
|
|
|
|
|
|
|
| | | | |
| | | | | |
modification
|
|
PR:000049941 |
RAC-alpha serine/threonine-protein kinase unphosphorylated 3
|
AKT1/UnPhos:3
|
"A RAC-alpha serine/threonine-protein kinase that lacks phosphorylation at the position equivalent to Ser-473 of the amino acid sequence represented by UniProtKB:P31749. Example: UniProtKB:P31749, Ser-473, PR:000026291." [PMID:27994061, PRO:LN]
|
|
|
|
|
|
|
| | | | | | |
| | | |
organism-modification
|
|
PR:000049942 |
RAC-alpha serine/threonine-protein kinase unphosphorylated 3 (mouse)
|
mAKT1/UnPhos:3
|
"A RAC-alpha serine/threonine-protein kinase unphosphorylated 3 in mouse. UniProtKB:P31750, Ser-473, PR:000026291." [PMID:27994061, PRO:LN]
|
|
|
|
|
