back to PRO homepage
  Home |   Linked Open Data |   Browse |  
Search

 |   Statistics |   Download
 RACE-PRO
 PRO tracker
 Community
 PRO Consortium
 Publications
 Documentation

Protein Ontology report - caspase-3-like protease
PR:000002196 - http://purl.obolibrary.org/obo/PR_000002196
 
  Protein Forms  Complex      
Ontology Information Show OBO stanza
  PRO ID
PR:000002196   
  PRO namecaspase-3-like protease 
  Definition"A protein that is a translation product of a gene family that includes CASP3, CASP6, and CASP7 genes. The core architecture consists of a Caspase domain (Pfam:PF00656). Encoded as zymogens, the activated proteins are cysteine proteases typically involved in apoptosis." [PRO:WCB] 
  PRO Categoryfamily 
  ParentPR:000000001 protein
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Family1                                                  Organism-Family 0                                        
         Gene4                                                  Organism-Gene 14                                        
         Sequence7                                                  Organism-Sequence 12                                        
         Modification11                                                  Organism-Modification 9                                        
  Term Hierarchy
  Visualization
DAG: OLS:
Back to top
Related Cross References

  Db identifiers
PIRSF:PIRSF015839
Back to top
Protein Forms  Switch to Extended View   

Category  
PRO Form Name
Short Name
Ann. Has Annotation?

Comp. In Complex?
family


PR:000002196 caspase-3-like protease
APAF1

gene


PR:000002312 caspase-3
CASP3

organism-gene


PR:P42574 caspase-3 (human)
hCASP3

organism-sequence


PR:P42574-1 caspase-3 isoform 1 (human)
hCASP3/iso:1

organism-modification


PR:000026876 caspase-3 isoform 1 cleaved 1 (human)
hCASP3/iso:1/Clv:1

Yes
organism-modification


PR:000026877 caspase-3 isoform 1 cleaved 2 (human)
hCASP3/iso:1/Clv:2

Yes
organism-modification


PR:000082245 caspase-3 cysteinylated 1 (human)
hCASP3/Cyst:1

organism-gene


PR:P55213 caspase-3 (rat)
rCASP3

organism-gene


PR:P70677 caspase-3 (mouse)
mCASP3

organism-sequence


PR:P70677-1 caspase-3 isoform 1 (mouse)
mCASP3/iso:1

organism-gene


PR:Q8MKI5 caspase-3 (dog)
dog-CASP3

sequence


PR:000002402 caspase-3 isoform 1
CASP3/iso:1

organism-sequence


PR:P42574-1 caspase-3 isoform 1 (human)
hCASP3/iso:1

organism-modification


PR:000026876 caspase-3 isoform 1 cleaved 1 (human)
hCASP3/iso:1/Clv:1

Yes
organism-modification


PR:000026877 caspase-3 isoform 1 cleaved 2 (human)
hCASP3/iso:1/Clv:2

Yes
organism-sequence


PR:P70677-1 caspase-3 isoform 1 (mouse)
mCASP3/iso:1

modification


PR:000002454 caspase-3 isoform 1 cleaved 1
CASP3/iso:1/Clv:1

Yes
organism-modification


PR:000026876 caspase-3 isoform 1 cleaved 1 (human)
hCASP3/iso:1/Clv:1

Yes
modification


PR:000002455 caspase-3 isoform 1 cleaved 2
CASP3/iso:1/Clv:2

Yes
organism-modification


PR:000026877 caspase-3 isoform 1 cleaved 2 (human)
hCASP3/iso:1/Clv:2

Yes
modification


PR:000018762 caspase-3 proteolytic cleavage product
CASP3/ClvPrd

modification


PR:000002454 caspase-3 isoform 1 cleaved 1
CASP3/iso:1/Clv:1

Yes
organism-modification


PR:000026876 caspase-3 isoform 1 cleaved 1 (human)
hCASP3/iso:1/Clv:1

Yes
modification


PR:000002455 caspase-3 isoform 1 cleaved 2
CASP3/iso:1/Clv:2

Yes
organism-modification


PR:000026877 caspase-3 isoform 1 cleaved 2 (human)
hCASP3/iso:1/Clv:2

Yes
gene


PR:000002315 caspase-6
CASP6

organism-gene


PR:A0A1D5PPP7 caspase-6 (chicken)
chick-CASP6

organism-gene


PR:O08738 caspase-6 (mouse)
mCASP6

organism-sequence


PR:O08738-1 caspase-6 isoform 1 (mouse)
mCASP6/iso:1

organism-gene


PR:O35397 caspase-6 (rat)
rCASP6

organism-gene


PR:P55212 caspase-6 (human)
hCASP6

organism-sequence


PR:P55212-1 caspase-6 isoform Alpha (human)
hCASP6/iso:Alpha

organism-modification


PR:000050093 caspase-6 subunit p18 (human)
hCASP6/p18

organism-modification


PR:000050094 caspase-6 subunit p11 (human)
hCASP6/p11

organism-sequence


PR:P55212-2 caspase-6 isoform Beta (human)
hCASP6/iso:Beta

organism-modification


PR:000045840 caspase-6 phosphorylated 1 (human)
hCASP6/Phos:1

organism-modification


PR:000067313 caspase-6 cysteinylated 1 (human)
hCASP6/Cyst:1

sequence


PR:000002406 caspase-6 isoform 1
CASP6/iso:1

organism-sequence


PR:P55212-1 caspase-6 isoform Alpha (human)
hCASP6/iso:Alpha

organism-modification


PR:000050093 caspase-6 subunit p18 (human)
hCASP6/p18

organism-modification


PR:000050094 caspase-6 subunit p11 (human)
hCASP6/p11

modification


PR:000002456 caspase-6 subunit p11
CASP6/p11

organism-modification


PR:000050094 caspase-6 subunit p11 (human)
hCASP6/p11

modification


PR:000002457 caspase-6 subunit p18
CASP6/p18

organism-modification


PR:000050093 caspase-6 subunit p18 (human)
hCASP6/p18

sequence


PR:000002407 caspase-6 isoform 2
CASP6/iso:2

organism-sequence


PR:O08738-1 caspase-6 isoform 1 (mouse)
mCASP6/iso:1

sequence


PR:000002408 caspase-6 isoform 3
CASP6/iso:3

organism-sequence


PR:P55212-2 caspase-6 isoform Beta (human)
hCASP6/iso:Beta

modification


PR:000018765 caspase-6 proteolytic cleavage product
CASP6/ClvPrd

modification


PR:000002456 caspase-6 subunit p11
CASP6/p11

organism-modification


PR:000050094 caspase-6 subunit p11 (human)
hCASP6/p11

modification


PR:000002457 caspase-6 subunit p18
CASP6/p18

organism-modification


PR:000050093 caspase-6 subunit p18 (human)
hCASP6/p18

gene


PR:000002316 caspase-7
CASP7

organism-gene


PR:F1NV61 caspase-7 (chicken)
chick-CASP7

organism-gene


PR:O01382 caspase drICE (fruit fly)
fly-CASP7

organism-gene


PR:P55210 caspase-7 (human)
hCASP7

organism-sequence


PR:P55210-1 caspase-7 isoform Alpha (human)
hCASP7/iso:Alpha

organism-modification


PR:000050105 caspase-7 subunit p20 (human)
hCASP7/p20

organism-modification


PR:000050106 caspase-7 subunit p11 (human)
hCASP7/p11

organism-sequence


PR:P55210-2 caspase-7 isoform Beta (human)
hCASP7/iso:Beta

organism-sequence


PR:P55210-3 caspase-7 isoform Alpha' (human)
hCASP7/iso:Alpha'

organism-sequence


PR:P55210-4 caspase-7 isoform h4 (human)
hCASP7/iso:h4

organism-gene


PR:P97864 caspase-7 (mouse)
mCASP7

organism-sequence


PR:P97864-1 caspase-7 isoform 1 (mouse)
mCASP7/iso:1

sequence


PR:000002409 caspase-7 isoform 1
CASP7/iso:1

organism-sequence


PR:P55210-1 caspase-7 isoform Alpha (human)
hCASP7/iso:Alpha

organism-modification


PR:000050105 caspase-7 subunit p20 (human)
hCASP7/p20

organism-modification


PR:000050106 caspase-7 subunit p11 (human)
hCASP7/p11

organism-sequence


PR:P97864-1 caspase-7 isoform 1 (mouse)
mCASP7/iso:1

modification


PR:000002458 caspase-7 subunit p11
CASP7/p11

organism-modification


PR:000050106 caspase-7 subunit p11 (human)
hCASP7/p11

modification


PR:000002459 caspase-7 subunit p20
CASP7/p20

organism-modification


PR:000050105 caspase-7 subunit p20 (human)
hCASP7/p20

sequence


PR:000002410 caspase-7 isoform 2
CASP7/iso:2

organism-sequence


PR:P55210-2 caspase-7 isoform Beta (human)
hCASP7/iso:Beta

sequence


PR:000002411 caspase-7 isoform 3
CASP7/iso:3

organism-sequence


PR:P55210-3 caspase-7 isoform Alpha' (human)
hCASP7/iso:Alpha'

modification


PR:000018766 caspase-7, initiator methionine removed form
CASP7/InitMet-

modification


PR:000018767 caspase-7 proteolytic cleavage product
CASP7/ClvPrd

modification


PR:000002458 caspase-7 subunit p11
CASP7/p11

organism-modification


PR:000050106 caspase-7 subunit p11 (human)
hCASP7/p11

modification


PR:000002459 caspase-7 subunit p20
CASP7/p20

organism-modification


PR:000050105 caspase-7 subunit p20 (human)
hCASP7/p20

gene


PR:000005054 caspase-14
CASP14

organism-gene


PR:O89094 caspase-14 (mouse)
mCASP14

organism-sequence


PR:O89094-1 caspase-14 isoform m1 (mouse)
mCASP14/iso:m1

organism-sequence


PR:O89094-2 caspase-14 isoform m2 (mouse)
mCASP14/iso:m2

organism-gene


PR:P31944 caspase-14 (human)
hCASP14

modification


PR:000019242 caspase-14 proteolytic cleavage product
CASP14/ClvPrd

Back to top
APAF1 forms found in complexes   

APAF1 Component
 Complexes
PR:000002454 CASP3/iso:1/Clv:1 PR:000026878 caspase-3 complex
PR:000002455 CASP3/iso:1/Clv:2 PR:000026878 caspase-3 complex
PR:000026876 hCASP3/iso:1/Clv:1 PR:000026879 caspase-3 complex (human)
PR:000026877 hCASP3/iso:1/Clv:2 PR:000026879 caspase-3 complex (human)