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Protein Ontology report - CASP8 and FADD-like apoptosis regulator
PR:000002282 - http://purl.obolibrary.org/obo/PR_000002282
 
  Protein Forms      
Ontology Information Show OBO stanza
  PRO ID
PR:000002282   
  PRO nameCASP8 and FADD-like apoptosis regulator 
  Synonyms
PRO-Short-label: EXACT:CFLAR
Gene-based: RELATED:CASH | CASP8AP1 | CLARP | MRIT
Other: EXACT:c-FLIP | caspase homolog | caspase-eight-related protein | caspase-like apoptosis regulatory protein | casper | cellular FLICE-like inhibitory protein | FADD-like antiapoptotic molecule 1 | FLAME-1 | I-FLICE | inhibitor of FLICE | MACH-related inducer of toxicity | usurpin
  Definition"A caspase-8-like protease that is a translation product of the human CFLAR gene or a 1:1 ortholog thereof." [PRO:WCB] 
  PRO Categorygene 
  ParentPR:000002197 caspase-8-like protease
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Gene1                                                  Organism-Gene 2                                        
         Sequence0                                                  Organism-Sequence 17                                        
         Modification0                                                  Organism-Modification 2                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Protein Forms Switch to Compact View   

Category  
PRO ID
Name
Short Name
Definition
Ann. Has Annotation?

Comp. In Complex?
gene


PR:000002282
CASP8 and FADD-like apoptosis regulator
CFLAR
"A caspase-8-like protease that is a translation product of the human CFLAR gene or a 1:1 ortholog thereof." [PRO:WCB]

organism-gene


PR:O15519
CASP8 and FADD-like apoptosis regulator (human)
hCFLAR
"A CASP8 and FADD-like apoptosis regulator that is encoded in the genome of human." [PRO:WCB, UniProtKB:O15519]

organism-sequence


PR:O15519-1
CASP8 and FADD-like apoptosis regulator isoform h1 (human)
hCFLAR/iso:h1
"A CASP8 and FADD-like apoptosis regulator (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:O15519-1." [PRO:DNx, UniProtKB:O15519]

organism-modification


PR:000064786
CASP8 and FADD-like apoptosis regulator isoform h1 ubiquitinated 1 (human)
hCFLAR/iso:h1/Ubiq:1
"A CASP8 and FADD-like apoptosis regulator isoform h1 (human) that has been ubiquitinated on the residues at the positions equivalent to Lys-460, Lys-462, Lys-473, and Lys-474 of the amino acid sequence represented by UniProtKB:O15519-1. UniProtKB:O15519-1, Lys-460/Lys-462/Lys-473/Lys-474, MOD:01148." [PRO:DNx, Reactome:R-HSA-9818805]

organism-sequence


PR:O15519-10
CASP8 and FADD-like apoptosis regulator isoform h10 (human)
hCFLAR/iso:h10
"A CASP8 and FADD-like apoptosis regulator (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:O15519-10." [PRO:DNx, UniProtKB:O15519]

organism-sequence


PR:O15519-11
CASP8 and FADD-like apoptosis regulator isoform h11 (human)
hCFLAR/iso:h11
"A CASP8 and FADD-like apoptosis regulator (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:O15519-11." [PRO:DNx, UniProtKB:O15519]

organism-sequence


PR:O15519-12
CASP8 and FADD-like apoptosis regulator isoform h12 (human)
hCFLAR/iso:h12
"A CASP8 and FADD-like apoptosis regulator (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:O15519-12." [PRO:DNx, UniProtKB:O15519]

organism-sequence


PR:O15519-13
CASP8 and FADD-like apoptosis regulator isoform h13 (human)
hCFLAR/iso:h13
"A CASP8 and FADD-like apoptosis regulator (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:O15519-13." [PRO:DNx, UniProtKB:O15519]

organism-sequence


PR:O15519-14
CASP8 and FADD-like apoptosis regulator isoform h14 (human)
hCFLAR/iso:h14
"A CASP8 and FADD-like apoptosis regulator (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:O15519-14." [PRO:DNx, UniProtKB:O15519]

organism-sequence


PR:O15519-15
CASP8 and FADD-like apoptosis regulator isoform h15 (human)
hCFLAR/iso:h15
"A CASP8 and FADD-like apoptosis regulator (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:O15519-15." [PRO:DNx, UniProtKB:O15519]

organism-sequence


PR:O15519-2
CASP8 and FADD-like apoptosis regulator isoform h2 (human)
hCFLAR/iso:h2
"A CASP8 and FADD-like apoptosis regulator (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:O15519-2." [PRO:DNx, UniProtKB:O15519]

organism-sequence


PR:O15519-3
CASP8 and FADD-like apoptosis regulator isoform h3 (human)
hCFLAR/iso:h3
"A CASP8 and FADD-like apoptosis regulator (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:O15519-3." [PRO:DNx, UniProtKB:O15519]

organism-sequence


PR:O15519-4
CASP8 and FADD-like apoptosis regulator isoform h4 (human)
hCFLAR/iso:h4
"A CASP8 and FADD-like apoptosis regulator (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:O15519-4." [PRO:DNx, UniProtKB:O15519]

organism-sequence


PR:O15519-5
CASP8 and FADD-like apoptosis regulator isoform h5 (human)
hCFLAR/iso:h5
"A CASP8 and FADD-like apoptosis regulator (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:O15519-5." [PRO:DNx, UniProtKB:O15519]

organism-sequence


PR:O15519-6
CASP8 and FADD-like apoptosis regulator isoform h6 (human)
hCFLAR/iso:h6
"A CASP8 and FADD-like apoptosis regulator (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:O15519-6." [PRO:DNx, UniProtKB:O15519]

organism-sequence


PR:O15519-7
CASP8 and FADD-like apoptosis regulator isoform h7 (human)
hCFLAR/iso:h7
"A CASP8 and FADD-like apoptosis regulator (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:O15519-7." [PRO:DNx, UniProtKB:O15519]

organism-sequence


PR:O15519-8
CASP8 and FADD-like apoptosis regulator isoform h8 (human)
hCFLAR/iso:h8
"A CASP8 and FADD-like apoptosis regulator (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:O15519-8." [PRO:DNx, UniProtKB:O15519]

organism-sequence


PR:O15519-9
CASP8 and FADD-like apoptosis regulator isoform h9 (human)
hCFLAR/iso:h9
"A CASP8 and FADD-like apoptosis regulator (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:O15519-9." [PRO:DNx, UniProtKB:O15519]

organism-modification


PR:000081836
CASP8 and FADD-like apoptosis regulator deaminated 1 (human)
hCFLAR/Deam:1
"A CASP8 and FADD-like apoptosis regulator (human) that has been deaminated on the residue at the position equivalent to Asn-200 of the amino acid sequence represented by UniProtKB:O15519-1. Example: UniProtKB:O15519-1, Asn-200, MOD:00684." [IEDB_epitope:1587251, PRO:DNx]

organism-gene


PR:O35732
CASP8 and FADD-like apoptosis regulator (mouse)
mCFLAR
"A CASP8 and FADD-like apoptosis regulator that is encoded in the genome of mouse." [OMA:O35732, PRO:DNx]

organism-sequence


PR:O35732-1
CASP8 and FADD-like apoptosis regulator isoform m1 (mouse)
mCFLAR/iso:m1
"A CASP8 and FADD-like apoptosis regulator (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:O35732-1." [PRO:DNx, UniProtKB:O35732]

organism-sequence


PR:O35732-2
CASP8 and FADD-like apoptosis regulator isoform m2 (mouse)
mCFLAR/iso:m2
"A CASP8 and FADD-like apoptosis regulator (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:O35732-2." [PRO:DNx, UniProtKB:O35732]