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RACE-PRO
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Protein Ontology report - fractalkine isoform 1
PR:000002982 -
http://purl.obolibrary.org/obo/PR_000002982
Protein Forms
Annotations
Ontology Information
Show OBO stanza
PRO ID
PR:000002982
PRO name
fractalkine isoform 1
Synonyms
PRO-Short-label
:
EXACT:
CX3CL1/iso:1
Definition
"A fractalkine that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by
UniProtKB:Q9Z0D9-1
or a 1:1 ortholog thereof." [PRO:HJD]
PRO Category
sequence
Parent
PR:000001855
fractalkine
Terms by PRO Category
Organism-Independent
Organism-Specific
Category
Number of Terms
Category
Number of Terms
Sequence
1
Organism-Sequence
1
Modification
1
Organism-Modification
0
Term Hierarchy
Visualization
DAG:
OLS:
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Protein Forms
Switch to
Compact View
Category
PRO ID
Name
Short Name
Definition
Ann.
Has Annotation?
Comp.
In Complex?
sequence
PR:000002982
fractalkine isoform 1
CX3CL1/iso:1
"A fractalkine that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9Z0D9-1 or a 1:1 ortholog thereof." [PRO:HJD]
organism-sequence
PR:Q9Z0D9-1
CX3C chemokine receptor 1 isoform 1 (mouse)
mCX3CR1/iso:1
"A fractalkine isoform 1 that is encoded in the genome of mouse." [PRO:HJD]
Yes
modification
PR:000021941
fractalkine isoform 1, signal peptide removed form
CX3CL1/iso:1/SigPep-
"A fractalkine isoform 1 that has had the signal peptide removed." [PRO:DAN]
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Functional Annotation (PRO-centric view)
Switch to
GO Centric View
PRO Term
GO Annotation
Evidence
PR:Q9Z0D9-1
mCX3CR1/iso:1
acts_upstream_of_or_within
GO:0002282
microglial cell activation involved in immune response
MGI_ref:3639805;
PMID:16732273
GO:0019221
cytokine-mediated signaling pathway
MGI_ref:3833195;
PMID:18971423
GO:0021795
cerebral cortex cell migration
MGI_ref:3639805;
PMID:16732273
GO:0048246
macrophage chemotaxis
MGI_ref:3777228;
PMID:18322241
GO:2001240
negative regulation of extrinsic apoptotic signaling pathway in absence of ligand
MGI_ref:3833195;
PMID:18971423
