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Protein Ontology report - merlin isoform 1
PR:000003021 - http://purl.obolibrary.org/obo/PR_000003021
 
  Protein Forms  Annotations      
Ontology Information Show OBO stanza
  PRO ID
PR:000003021   
  PRO namemerlin isoform 1 
  Synonyms
PRO-Short-label: EXACT:NF2/iso:1
Other: EXACT:merlin isoform I
  Definition"A merlin that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P35240-1 or a 1:1 ortholog thereof." [PMID:18071304
  PRO Categorysequence 
  ParentPR:000003020 merlin
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Sequence1                                                  Organism-Sequence 2                                        
         Modification3                                                  Organism-Modification 0                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Protein Forms Switch to Compact View   

Category  

PRO ID

Name

Short Name

Definition

Ann. Has Annotation?

Comp. In Complex?
sequence



PR:000003021

merlin isoform 1

NF2/iso:1


"A merlin that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P35240-1 or a 1:1 ortholog thereof." [PMID:18071304]


organism-sequence



PR:P35240-1

merlin isoform 1 (human)

hNF2/iso:1


"A merlin isoform 1 that is encoded in the genome of human." [PMID:9430655, PRO:CNA]

Yes

organism-sequence



PR:P46662-1

merlin isoform 1 (mouse)

mNF2/iso:1


"A merlin isoform 1 that is encoded in the genome of mouse." [PRO:DNx, UniProtKB:P46662]


modification



PR:000003024

merlin isoform 1 phosphorylated form

NF2/iso:1/PhosRes+


"A merlin isoform 1 that includes at least one phosphorylated residue." [PRO:CNA]


modification



PR:000003025

merlin isoform 1 phosphorylated 1

NF2/iso:1/Phos:1


"A merlin isoform 1 phosphorylated form that is phosphorylated in a C-terminal Ser residue within the PKA consensus site. Example: UniProtKB:P35240-1, Ser-518, MOD:00046." [PMID:18071304, PRO:AL]


modification



PR:000003026

merlin isoform 1 phosphorylated 2

NF2/iso:1/Phos:2


"A merlin isoform 1 phosphorylated form that is phosphorylated in a Ser residue (PKA consensus site) located within the N-terminal actin binding site, and it is also phosphorylated on a C-terminal Ser residue." [PMID:18071304, PRO:AL]


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Functional Annotation (PRO-centric view) Switch to GO Centric View   
PRO Term GO Annotation Evidence
PR:P35240-1 hNF2/iso:1 enablesGO:0005515 protein binding with PR:O14745 EBP50 (human) PMID:15467741
GO:0005515 protein binding with PR:Q9H204 EG1 PMID:15467741
located_inGO:0005634 nucleus PMID:20178741