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Protein Ontology report - Bcl2-associated agonist of cell death isoform 1 phosphorylated form
PR:000003084 -
http://purl.obolibrary.org/obo/PR_000003084
Protein Forms
Annotations
Ontology Information
Show OBO stanza
PRO ID
PR:000003084
PRO name
Bcl2-associated agonist of cell death isoform 1 phosphorylated form
Synonyms
PRO-Short-label
:
EXACT:
BAD/iso:1/PhosRes+
Definition
"A Bcl2-associated agonist of cell death isoform 1 that includes at least one phosphorylated residue." [PRO:CNA]
PRO Category
modification
Parent
PR:000002280
Bcl2-associated agonist of cell death isoform 1
PR:000037070
phosphoprotein
Terms by PRO Category
Organism-Independent
Organism-Specific
Category
Number of Terms
Category
Number of Terms
Modification
9
Organism-Modification
8
Term Hierarchy
Visualization
DAG:
OLS:
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Protein Forms
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Compact View
Category
PRO ID
Name
Short Name
Definition
Ann.
Has Annotation?
Comp.
In Complex?
modification
PR:000003084
Bcl2-associated agonist of cell death isoform 1 phosphorylated form
BAD/iso:1/PhosRes+
"A Bcl2-associated agonist of cell death isoform 1 that includes at least one phosphorylated residue." [PRO:CNA]
modification
PR:000003085
Bcl2-associated agonist of cell death isoform 1 phosphorylated 1
BAD/iso:1/Phos:1
"A Bcl2-associated agonist of cell death isoform 1 phosphorylated form in which the phosphorylation occurs at two Ser residues which are the major sites of phosphorylation by PKA and AKT signaling. The sites are the indicated serines within the RxRxxSxP motifs. Phosphorylation on these residues favors binding to 14-3-3 proteins. Example: UniProtKB:Q61337-1, Ser-112/Ser-136, MOD:00046." [PMID:10949026, PMID:8929531, PMID:9346240, PRO:CNA, PRO:DAN, PRO:JAN]
organism-modification
PR:000026167
Bcl2-associated agonist of cell death isoform 1 phosphorylated 1 (mouse)
mBAD/iso:1/Phos:1
"A Bcl2-associated agonist of cell death isoform 1 phosphorylated 1 in mouse. UniProtKB:Q61337-1, Ser-112/Ser-136, MOD:00046." [PMID:10949026, PMID:8929531, PMID:9346240, PRO:JAN]
Yes
modification
PR:000003086
Bcl2-associated agonist of cell death isoform 1 phosphorylated 2
BAD/iso:1/Phos:2
"A Bcl2-associated agonist of cell death isoform 1 phosphorylated form in which the phosphorylation occurs at the indicated Ser residues within each of two RxRxxSxP motifs, and within the RRxS motif located in the BH3 domain. Example: UniProtKB:Q61337-1, Ser-112/Ser-136/Ser-155, MOD:00046." [PMID:10880354, PMID:10949026, PRO:CNA, PRO:DAN, PRO:JAN]
organism-modification
PR:000026133
Bcl2-associated agonist of cell death isoform 1 phosphorylated 2 (mouse)
mBAD/iso:1/Phos:2
"A Bcl2-associated agonist of cell death isoform 1 phosphorylated 2 in mouse. UniProtKB:Q61337-1, Ser-112/Ser-136/Ser-155, MOD:00046." [PMID:10880354, PMID:10949026, PRO:JAN]
Yes
modification
PR:000003087
Bcl2-associated agonist of cell death isoform 1 phosphorylated 3
BAD/iso:1/Phos:3
"A Bcl2-associated agonist of cell death isoform 1 phosphorylated form in which the phosphorylation occurs upon activation of the MAPK pathway. Phosphorylation on this residue favors binding to 14-3-3 proteins. Example: UniProtKB:Q61337-1, Ser-112, MOD:00046." [PMID:10195903, PMID:10597268, PMID:10880354, PRO:JAN]
organism-modification
PR:000026134
Bcl2-associated agonist of cell death isoform 1 phosphorylated 3 (rat)
rBAD/iso:1/Phos:3
"A Bcl2-associated agonist of cell death isoform 1 phosphorylated 3 in rat. UniProtKB:O35147-1, Ser-112, MOD:00046." [PMID:10195903, PMID:10597268, PRO:JAN]
Yes
modification
PR:000003233
Bcl2-associated agonist of cell death isoform 1 phosphorylated 4
BAD/iso:1/Phos:4
"A Bcl2-associated agonist of cell death isoform 1 phosphorylated form in which the phosphorylation occurs at a Thr residue by the action of JNK1. Example: UniProtKB:Q61337-1, Thr-201, MOD:00047." [PMID:14967141, PRO:JAN]
organism-modification
PR:000026135
Bcl2-associated agonist of cell death isoform 1 phosphorylated 4 (mouse)
mBAD/iso:1/Phos:4
"A Bcl2-associated agonist of cell death isoform 1 phosphorylated 4 in mouse. UniProtKB:Q61337-1, Thr-201, MOD:00047." [PMID:14967141, PRO:JAN]
Yes
modification
PR:000003238
Bcl2-associated agonist of cell death isoform 1 phosphorylated 5
BAD/iso:1/Phos:5
"A Bcl2-associated agonist of cell death isoform 1 phosphorylated form in which the phosphorylation occurs at one of the two Ser residues which are the major sites of phosphorylation by MAPK and AKT signaling. Phosphorylation on this residue favors binding to 14-3-3 proteins. Example: UniProtKB:Q61337-1, Ser-136, MOD:00046." [PMID:12049737, PRO:JAN]
organism-modification
PR:000026136
Bcl2-associated agonist of cell death isoform 1 phosphorylated 5 (mouse)
mBAD/iso:1/Phos:5
"A Bcl2-associated agonist of cell death isoform 1 phosphorylated 5 in mouse. UniProtKB:Q61337-1, Ser-136, MOD:00046." [PMID:12049737, PRO:JAN]
Yes
modification
PR:000003269
Bcl2-associated agonist of cell death isoform 1 phosphorylated 6
BAD/iso:1/Phos:6
"A Bcl2-associated agonist of cell death isoform 1 phosphorylated form in which the phosphorylation occurs by the action of cdc-2. Example: UniProtKB:Q61337-1, Ser-128/Ser-136, MOD:00046." [PMID:12049737, PRO:JAN]
organism-modification
PR:000026137
Bcl2-associated agonist of cell death isoform 1 phosphorylated 6 (mouse)
mBAD/iso:1/Phos:6
"A Bcl2-associated agonist of cell death isoform 1 phosphorylated 6 in mouse. UniProtKB:Q61337-1, Ser-128/Ser-136, MOD:00046." [PMID:12049737, PRO:JAN]
Yes
modification
PR:000025849
Bcl2-associated agonist of cell death isoform 1 phosphorylated 7
BAD/iso:1/Phos:7
"A Bcl2-associated agonist of cell death isoform 1 phosphorylated form in which the phosphorylation occurs at two Ser residues by activation of RSK. Phosphorylation on these residues favors binding to 14-3-3 proteins. Example: UniProtKB:Q61337-1, Ser-112/Ser-155, MOD:00046." [PMID:10880354, PRO:CNA]
organism-modification
PR:000026138
Bcl2-associated agonist of cell death isoform 1 phosphorylated 7 (mouse)
mBAD/iso:1/Phos:7
"A Bcl2-associated agonist of cell death isoform 1 phosphorylated 7 in mouse. UniProtKB:Q61337-1, Ser-112/Ser-155, MOD:00046." [PMID:10880354, PRO:CNA]
modification
PR:000025850
Bcl2-associated agonist of cell death isoform 1 phosphorylated 8
BAD/iso:1/Phos:8
"A Bcl2-associated agonist of cell death isoform 1 phosphorylated form in which the phosphorylation occurs at a Ser residue at the PKA/RSK consensus sequence RRxS. Phosphorylation on this residue favors binding to 14-3-3 proteins. Example: UniProtKB:Q61337-1, Ser-155, MOD:00046." [PMID:10880354, PRO:CNA]
organism-modification
PR:000026139
Bcl2-associated agonist of cell death isoform 1 phosphorylated 8 (mouse)
mBAD/iso:1/Phos:8
"A Bcl2-associated agonist of cell death isoform 1 phosphorylated 8 in mouse. UniProtKB:Q61337-1, Ser-155, MOD:00046." [PMID:10880354, PRO:CNA]
Yes
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Functional Annotation (PRO-centric view)
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GO Centric View
PRO Term
GO Annotation
Evidence
PR:000026133
mBAD/iso:1/Phos:2
UniProtKB:Q61337-1, Ser-112/Ser-136/Ser-155, MOD:00046
acts_upstream_of_or_within
GO:0043066
negative regulation of apoptotic process
PMID:10949026
enables
NOT
GO:0005515
protein binding
with
PR:000003237
fam:14-3-3
PMID:10949026
NOT
GO:0005515
protein binding
with
PR:P63101-1
PMID:10949026
NOT
GO:0005515
protein binding
with
PR:Q64373-1
PMID:10949026
NOT
GO:0005515
protein binding
with
PR:Q07817-1
PMID:10949026
PR:000026134
rBAD/iso:1/Phos:3
UniProtKB:O35147-1, Ser-112, MOD:00046
enables
decreased
GO:0005515
protein binding
with
PR:P53563-1
PMID:10195903
GO:0019902
phosphatase binding
PMID:10195903
located_in
GO:0005829
cytosol
PMID:10195903
PR:000026135
mBAD/iso:1/Phos:4
UniProtKB:Q61337-1, Thr-201, MOD:00047
acts_upstream_of_or_within
GO:0043066
negative regulation of apoptotic process
PMID:14967141
enables
decreased
GO:0005515
protein binding
with
PR:Q64373-1
PMID:14967141
PR:000026136
mBAD/iso:1/Phos:5
UniProtKB:Q61337-1, Ser-136, MOD:00046
enables
GO:0005515
protein binding
with
PR:P63101
KCIP-1 (mouse)
PMID:12049737
PR:000026137
mBAD/iso:1/Phos:6
UniProtKB:Q61337-1, Ser-128/Ser-136, MOD:00046
acts_upstream_of_or_within
GO:0051402
neuron apoptotic process
PMID:12049737
PR:000026139
mBAD/iso:1/Phos:8
UniProtKB:Q61337-1, Ser-155, MOD:00046
enables
GO:0071889
14-3-3 protein binding
with
PR:P61982
mYWHAG
PMID:10880354
PR:000026167
mBAD/iso:1/Phos:1
UniProtKB:Q61337-1, Ser-112/Ser-136, MOD:00046
enables
decreased
GO:0005515
protein binding
with
PR:P62258-1
PMID:12049737
decreased
GO:0005515
protein binding
with
PR:Q07817-1
PMID:12049737
decreased
GO:0005515
protein binding
with
PR:Q9CQV8
KCIP-1 (mouse)
PMID:12049737
decreased
GO:0005515
protein binding
with
PR:P63101
KCIP-1 (mouse)
PMID:12049737