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Protein Ontology report - Bcl2-associated agonist of cell death isoform 1 phosphorylated form
PR:000003084 - http://purl.obolibrary.org/obo/PR_000003084
 
  Protein Forms  Annotations      
Ontology Information Show OBO stanza
  PRO ID
PR:000003084   
  PRO nameBcl2-associated agonist of cell death isoform 1 phosphorylated form 
  Synonyms
PRO-Short-label: EXACT:BAD/iso:1/PhosRes+
  Definition"A Bcl2-associated agonist of cell death isoform 1 that includes at least one phosphorylated residue." [PRO:CNA] 
  PRO Categorymodification 
  ParentPR:000002280 Bcl2-associated agonist of cell death isoform 1
PR:000037070 phosphoprotein
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Modification9                                                  Organism-Modification 8                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Protein Forms Switch to Compact View   

Category  

PRO ID

Name

Short Name

Definition

Ann. Has Annotation?

Comp. In Complex?
modification



PR:000003084

Bcl2-associated agonist of cell death isoform 1 phosphorylated form

BAD/iso:1/PhosRes+


"A Bcl2-associated agonist of cell death isoform 1 that includes at least one phosphorylated residue." [PRO:CNA]


modification



PR:000003085

Bcl2-associated agonist of cell death isoform 1 phosphorylated 1

BAD/iso:1/Phos:1


"A Bcl2-associated agonist of cell death isoform 1 phosphorylated form in which the phosphorylation occurs at two Ser residues which are the major sites of phosphorylation by PKA and AKT signaling. The sites are the indicated serines within the RxRxxSxP motifs. Phosphorylation on these residues favors binding to 14-3-3 proteins. Example: UniProtKB:Q61337-1, Ser-112/Ser-136, MOD:00046." [PMID:10949026, PMID:8929531, PMID:9346240, PRO:CNA, PRO:DAN, PRO:JAN]


organism-modification



PR:000026167

Bcl2-associated agonist of cell death isoform 1 phosphorylated 1 (mouse)

mBAD/iso:1/Phos:1


"A Bcl2-associated agonist of cell death isoform 1 phosphorylated 1 in mouse. UniProtKB:Q61337-1, Ser-112/Ser-136, MOD:00046." [PMID:10949026, PMID:8929531, PMID:9346240, PRO:JAN]

Yes

modification



PR:000003086

Bcl2-associated agonist of cell death isoform 1 phosphorylated 2

BAD/iso:1/Phos:2


"A Bcl2-associated agonist of cell death isoform 1 phosphorylated form in which the phosphorylation occurs at the indicated Ser residues within each of two RxRxxSxP motifs, and within the RRxS motif located in the BH3 domain. Example: UniProtKB:Q61337-1, Ser-112/Ser-136/Ser-155, MOD:00046." [PMID:10880354, PMID:10949026, PRO:CNA, PRO:DAN, PRO:JAN]


organism-modification



PR:000026133

Bcl2-associated agonist of cell death isoform 1 phosphorylated 2 (mouse)

mBAD/iso:1/Phos:2


"A Bcl2-associated agonist of cell death isoform 1 phosphorylated 2 in mouse. UniProtKB:Q61337-1, Ser-112/Ser-136/Ser-155, MOD:00046." [PMID:10880354, PMID:10949026, PRO:JAN]

Yes

modification



PR:000003087

Bcl2-associated agonist of cell death isoform 1 phosphorylated 3

BAD/iso:1/Phos:3


"A Bcl2-associated agonist of cell death isoform 1 phosphorylated form in which the phosphorylation occurs upon activation of the MAPK pathway. Phosphorylation on this residue favors binding to 14-3-3 proteins. Example: UniProtKB:Q61337-1, Ser-112, MOD:00046." [PMID:10195903, PMID:10597268, PMID:10880354, PRO:JAN]


organism-modification



PR:000026134

Bcl2-associated agonist of cell death isoform 1 phosphorylated 3 (rat)

rBAD/iso:1/Phos:3


"A Bcl2-associated agonist of cell death isoform 1 phosphorylated 3 in rat. UniProtKB:O35147-1, Ser-112, MOD:00046." [PMID:10195903, PMID:10597268, PRO:JAN]

Yes

modification



PR:000003233

Bcl2-associated agonist of cell death isoform 1 phosphorylated 4

BAD/iso:1/Phos:4


"A Bcl2-associated agonist of cell death isoform 1 phosphorylated form in which the phosphorylation occurs at a Thr residue by the action of JNK1. Example: UniProtKB:Q61337-1, Thr-201, MOD:00047." [PMID:14967141, PRO:JAN]


organism-modification



PR:000026135

Bcl2-associated agonist of cell death isoform 1 phosphorylated 4 (mouse)

mBAD/iso:1/Phos:4


"A Bcl2-associated agonist of cell death isoform 1 phosphorylated 4 in mouse. UniProtKB:Q61337-1, Thr-201, MOD:00047." [PMID:14967141, PRO:JAN]

Yes

modification



PR:000003238

Bcl2-associated agonist of cell death isoform 1 phosphorylated 5

BAD/iso:1/Phos:5


"A Bcl2-associated agonist of cell death isoform 1 phosphorylated form in which the phosphorylation occurs at one of the two Ser residues which are the major sites of phosphorylation by MAPK and AKT signaling. Phosphorylation on this residue favors binding to 14-3-3 proteins. Example: UniProtKB:Q61337-1, Ser-136, MOD:00046." [PMID:12049737, PRO:JAN]


organism-modification



PR:000026136

Bcl2-associated agonist of cell death isoform 1 phosphorylated 5 (mouse)

mBAD/iso:1/Phos:5


"A Bcl2-associated agonist of cell death isoform 1 phosphorylated 5 in mouse. UniProtKB:Q61337-1, Ser-136, MOD:00046." [PMID:12049737, PRO:JAN]

Yes

modification



PR:000003269

Bcl2-associated agonist of cell death isoform 1 phosphorylated 6

BAD/iso:1/Phos:6


"A Bcl2-associated agonist of cell death isoform 1 phosphorylated form in which the phosphorylation occurs by the action of cdc-2. Example: UniProtKB:Q61337-1, Ser-128/Ser-136, MOD:00046." [PMID:12049737, PRO:JAN]


organism-modification



PR:000026137

Bcl2-associated agonist of cell death isoform 1 phosphorylated 6 (mouse)

mBAD/iso:1/Phos:6


"A Bcl2-associated agonist of cell death isoform 1 phosphorylated 6 in mouse. UniProtKB:Q61337-1, Ser-128/Ser-136, MOD:00046." [PMID:12049737, PRO:JAN]

Yes

modification



PR:000025849

Bcl2-associated agonist of cell death isoform 1 phosphorylated 7

BAD/iso:1/Phos:7


"A Bcl2-associated agonist of cell death isoform 1 phosphorylated form in which the phosphorylation occurs at two Ser residues by activation of RSK. Phosphorylation on these residues favors binding to 14-3-3 proteins. Example: UniProtKB:Q61337-1, Ser-112/Ser-155, MOD:00046." [PMID:10880354, PRO:CNA]


organism-modification



PR:000026138

Bcl2-associated agonist of cell death isoform 1 phosphorylated 7 (mouse)

mBAD/iso:1/Phos:7


"A Bcl2-associated agonist of cell death isoform 1 phosphorylated 7 in mouse. UniProtKB:Q61337-1, Ser-112/Ser-155, MOD:00046." [PMID:10880354, PRO:CNA]


modification



PR:000025850

Bcl2-associated agonist of cell death isoform 1 phosphorylated 8

BAD/iso:1/Phos:8


"A Bcl2-associated agonist of cell death isoform 1 phosphorylated form in which the phosphorylation occurs at a Ser residue at the PKA/RSK consensus sequence RRxS. Phosphorylation on this residue favors binding to 14-3-3 proteins. Example: UniProtKB:Q61337-1, Ser-155, MOD:00046." [PMID:10880354, PRO:CNA]


organism-modification



PR:000026139

Bcl2-associated agonist of cell death isoform 1 phosphorylated 8 (mouse)

mBAD/iso:1/Phos:8


"A Bcl2-associated agonist of cell death isoform 1 phosphorylated 8 in mouse. UniProtKB:Q61337-1, Ser-155, MOD:00046." [PMID:10880354, PRO:CNA]

Yes

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Functional Annotation (PRO-centric view) Switch to GO Centric View   
PRO Term GO Annotation Evidence
PR:000026133 mBAD/iso:1/Phos:2
UniProtKB:Q61337-1, Ser-112/Ser-136/Ser-155, MOD:00046
acts_upstream_of_or_withinGO:0043066 negative regulation of apoptotic process PMID:10949026
enablesNOT GO:0005515 protein binding with PR:000003237 fam:14-3-3 PMID:10949026
NOT GO:0005515 protein binding with PR:P63101-1 PMID:10949026
NOT GO:0005515 protein binding with PR:Q64373-1 PMID:10949026
NOT GO:0005515 protein binding with PR:Q07817-1 PMID:10949026
PR:000026134 rBAD/iso:1/Phos:3
UniProtKB:O35147-1, Ser-112, MOD:00046
enablesdecreased GO:0005515 protein binding with PR:P53563-1 PMID:10195903
GO:0019902 phosphatase binding PMID:10195903
located_inGO:0005829 cytosol PMID:10195903
PR:000026135 mBAD/iso:1/Phos:4
UniProtKB:Q61337-1, Thr-201, MOD:00047
acts_upstream_of_or_withinGO:0043066 negative regulation of apoptotic process PMID:14967141
enablesdecreased GO:0005515 protein binding with PR:Q64373-1 PMID:14967141
PR:000026136 mBAD/iso:1/Phos:5
UniProtKB:Q61337-1, Ser-136, MOD:00046
enablesGO:0005515 protein binding with PR:P63101 KCIP-1 (mouse) PMID:12049737
PR:000026137 mBAD/iso:1/Phos:6
UniProtKB:Q61337-1, Ser-128/Ser-136, MOD:00046
acts_upstream_of_or_withinGO:0051402 neuron apoptotic process PMID:12049737
PR:000026139 mBAD/iso:1/Phos:8
UniProtKB:Q61337-1, Ser-155, MOD:00046
enablesGO:0071889 14-3-3 protein binding with PR:P61982 mYWHAG PMID:10880354
PR:000026167 mBAD/iso:1/Phos:1
UniProtKB:Q61337-1, Ser-112/Ser-136, MOD:00046
enablesdecreased GO:0005515 protein binding with PR:P62258-1 PMID:12049737
decreased GO:0005515 protein binding with PR:Q07817-1 PMID:12049737
decreased GO:0005515 protein binding with PR:Q9CQV8 KCIP-1 (mouse) PMID:12049737
decreased GO:0005515 protein binding with PR:P63101 KCIP-1 (mouse) PMID:12049737