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Protein Ontology report - apoptosis regulator Bcl-2 isoform 1 phosphorylated 1

PR:000003089 - http://purl.obolibrary.org/obo/PR_000003089

Protein Forms

Annotations

Ontology Information

Show OBO stanza

PRO ID

PR:000003089

PRO name

apoptosis regulator Bcl-2 isoform 1 phosphorylated 1

Synonyms

PRO-Short-label:

EXACT:

BCL2/iso:1/Phos:1

Definition

"An apoptosis regulator Bcl-2 isoform 1 phosphorylated form in which the phosphorylation occurs by the action of PKC. Example: UniProtKB:P10417-1, Ser-70, MOD:00046." [PMID:9115213, PMID:9852076, PRO:JAN]

PRO Category

modification

Parent

PR:000003088 apoptosis regulator Bcl-2 isoform 1 phosphorylated form

Terms by PRO Category

Organism-Independent		Organism-Specific
Category	Number of Terms	Category	Number of Terms
Modification	1	Organism-Modification	1

Term Hierarchy
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DAG:

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Protein Forms

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Category

PRO Form Name

Short Name

Ann. Has Annotation?

Comp. In Complex?

modification

PR:000003089 apoptosis regulator Bcl-2 isoform 1 phosphorylated 1

BCL2/iso:1/Phos:1

organism-modification

PR:000036633 apoptosis regulator Bcl-2 isoform 1 phosphorylated 1 (mouse)

mBCL2/iso:1/Phos:1

Yes

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Functional Annotation (PRO-centric view)

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PRO Term	GO Annotation		Evidence
PR:000036633 mBCL2/iso:1/Phos:1 UniProtKB:P10417-1, Ser-70, MOD:00046	acts_upstream_of_or_within	GO:0043066 negative regulation of apoptotic process	PMID:9115213; PMID:9852076
	enables	GO:0005515 protein binding with PR:Q07813 Bax	PMID:9115213; PMID:9852076
	enables	GO:0019902 phosphatase binding	PMID:9115213; PMID:9852076
	located_in	GO:0016020 membrane	PMID:9115213; PMID:9852076