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Protein Ontology report - subtilisin/kexin-type proprotein convertase
PR:000003136 - http://purl.obolibrary.org/obo/PR_000003136
 
  Protein Forms  Annotations      
Ontology Information Show OBO stanza
  PRO ID
PR:000003136   
  PRO namesubtilisin/kexin-type proprotein convertase 
  PRO Categoryfamily 
  ParentPR:000000001 protein
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Family1                                                  Organism-Family 0                                        
         Gene6                                                  Organism-Gene 22                                        
         Sequence5                                                  Organism-Sequence 53                                        
         Modification8                                                  Organism-Modification 13                                        
  Term Hierarchy
  Visualization
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Related Cross References

  Db identifiers
PIRSF:PIRSF001179
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Protein Forms Switch to Compact View   

Category  

PRO ID

Name

Short Name

Definition

Ann. Has Annotation?

Comp. In Complex?
family



PR:000003136

subtilisin/kexin-type proprotein convertase

DIABLO/iso:1/TransPep-





gene



PR:000003137

furin

FURIN


"A subtilisin/kexin-type proprotein convertase that is a translation product of the human FURIN gene or a 1:1 ortholog thereof." [PRO:CNA]


organism-gene



PR:O17798

furin-like protease kpc-1 (worm)

FURIN (worm)


"A furin that is encoded in the genome of worm." [OMA:O17798, PRO:CNA]


organism-gene



PR:P09958

furin (human)

hFURIN


"A furin that is encoded in the genome of human." [PRO:CNA, UniProtKB:P09958]


organism-sequence



PR:P09958-1

furin isoform 1 (human)

hFURIN/iso:1


"A furin isoform 1 that is encoded in the genome of human." [PRO:CNA]


organism-modification



PR:000035903

furin active form (human)

hFURIN/active


"A furin active form in human. UniProtKB:P09958, 108-794." [PMID:1629222, Reactome:R-HSA-1181103, Reactome:R-HSA-157049, Reactome:R-HSA-2159856, Reactome:R-HSA-448351]


organism-modification



PR:000082386

furin cysteinylated 1 (human)

hFURIN/Cyst:1


"A furin (human) that has been cysteinylated on the residue at the position equivalent to Cys-450 of the amino acid sequence represented by UniProtKB:P09958. UniProtKB:P09958, Cys-450, MOD:00765." [IEDB_epitope:2117361, PRO:DNx]


organism-gene



PR:P23188

furin (mouse)

mFURIN


"A furin that is encoded in the genome of mouse." [OMA:P23188, PRO:DNx]


organism-sequence



PR:P23188-1

furin isoform 1 (mouse)

mFURIN/iso:1


"A furin isoform 1 that is encoded in the genome of mouse." [PRO:CNA]


organism-gene



PR:P23377

furin (rat)

rFURIN


"A furin that is encoded in the genome of rat." [OMA:P23377, PRO:DNx]


sequence



PR:000003147

furin isoform 1

FURIN/iso:1


"A furin that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P09958-1 or a 1:1 ortholog thereof." [PRO:CNA]


organism-sequence



PR:P09958-1

furin isoform 1 (human)

hFURIN/iso:1


"A furin isoform 1 that is encoded in the genome of human." [PRO:CNA]


organism-sequence



PR:P23188-1

furin isoform 1 (mouse)

mFURIN/iso:1


"A furin isoform 1 that is encoded in the genome of mouse." [PRO:CNA]


modification



PR:000018787

furin proteolytic cleavage product

FURIN/ClvPrd


"A furin that has been processed by proteolytic cleavage." [PRO:DNx]


modification



PR:000021921

furin, signal peptide removed form

FURIN/SigPep-


"A furin that has had the signal peptide removed." [PRO:DNx]


modification



PR:000003150

furin active form

FURIN/active


"A furin, signal peptide removed form that has been processed by subsequent removal of the inhibition peptide." [PRO:DAN]


modification



PR:000003151

furin active form phosphorylated form

FURIN/active/PhosRes+


"A furin active form that includes at least one phosphorylated residue." [PRO:CNA, PRO:DAN]


modification



PR:000003152

furin active form phosphorylated 1

FURIN/active/Phos:1


"A furin active form phosphorylated form in which the phosphorylation occurs at two Ser residues located in the acid cytoplasmic tail. Phosphorylation of mature furin is required for TGN localization of the endoprotease. Example: UniProtKB:P09958-1, 108-794, Ser-773/Ser-775, MOD:00046." [PMID:8846780, UniProtKB:P09958]


organism-modification



PR:000035903

furin active form (human)

hFURIN/active


"A furin active form in human. UniProtKB:P09958, 108-794." [PMID:1629222, Reactome:R-HSA-1181103, Reactome:R-HSA-157049, Reactome:R-HSA-2159856, Reactome:R-HSA-448351]


gene



PR:000012433

neuroendocrine convertase 1

PCSK1


"A subtilisin/kexin-type proprotein convertase that is a translation product of the human PCSK1 gene or a 1:1 ortholog thereof." [PRO:DNx]


organism-gene



PR:P28840

neuroendocrine convertase 1 (rat)

rPCSK1


"A neuroendocrine convertase 1 that is encoded in the genome of rat." [OMA:P28840, PRO:DNx]


organism-gene



PR:P29120

neuroendocrine convertase 1 (human)

hPCSK1


"A neuroendocrine convertase 1 that is encoded in the genome of human." [PRO:DNx, UniProtKB:P29120]


organism-sequence



PR:P29120-1

neuroendocrine convertase 1 isoform 1 (human)

hPCSK1/iso:1


"A neuroendocrine convertase 1 isoform 1 that is encoded in the genome of human." [PRO:DNx]


organism-sequence



PR:P29120-2

neuroendocrine convertase 1 isoform h2 (human)

hPCSK1/iso:h2


"A neuroendocrine convertase 1 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P29120-2." [PRO:DNx, UniProtKB:P29120]


organism-modification



PR:000056327

neuroendocrine convertase 1 O-glycosylated 1 (human)

hPCSK1/OGlyco:1


"A neuroendocrine convertase 1 (human) that has been O-glycosylated at the residue equivalent to Thr-632 of the amino acid sequence represented by UniProtKB:P29120-1, in which the glycan composition is represented by GlyTouCan:G43417UB. Example: UniProtKB:P29120-1, Thr-632, MOD:00005~GNO:G43417UB." [GlyGen:P29120-1, PMID:23234360, PRO:DNx]


organism-modification



PR:000075281

neuroendocrine convertase 1, mature form (human)

hPCSK1/mature


"A neuroendocrine convertase 1 (human) that has had the signal peptide and propeptide removed. Example: UniProtKB:P29120-1, 111-753." [PRO:DNx, Reactome:R-HSA-378951]


organism-gene



PR:P63239

neuroendocrine convertase 1 (mouse)

mPCSK1


"A neuroendocrine convertase 1 that is encoded in the genome of mouse." [OMA:P63239, PRO:DNx]


organism-sequence



PR:P63239-1

neuroendocrine convertase 1 isoform 1 (mouse)

mPCSK1/iso:1


"A neuroendocrine convertase 1 isoform 1 that is encoded in the genome of mouse." [PRO:DNx]


sequence



PR:000039210

neuroendocrine convertase 1 isoform 1

PCSK1/iso:1


"A neuroendocrine convertase 1 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P29120-1 or a 1:1 ortholog thereof." [PRO:DNx]


organism-sequence



PR:P29120-1

neuroendocrine convertase 1 isoform 1 (human)

hPCSK1/iso:1


"A neuroendocrine convertase 1 isoform 1 that is encoded in the genome of human." [PRO:DNx]


organism-sequence



PR:P63239-1

neuroendocrine convertase 1 isoform 1 (mouse)

mPCSK1/iso:1


"A neuroendocrine convertase 1 isoform 1 that is encoded in the genome of mouse." [PRO:DNx]


gene



PR:000012435

neuroendocrine convertase 2

PCSK2


"A subtilisin/kexin-type proprotein convertase that is a translation product of the human PCSK2 gene or a 1:1 ortholog thereof." [PRO:DNx]


organism-gene



PR:G5ECN9

neuroendocrine convertase 2 (worm)

PCSK2 (worm)


"A neuroendocrine convertase 2 that is encoded in the genome of worm." [OMA:G5ECN9, PRO:DNx]


organism-sequence



PR:G5ECN9-1

neuroendocrine convertase 2 isoform a (worm)

PCSK2/iso:a (worm)


"A neuroendocrine convertase 2 (worm) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:G5ECN9-1." [PRO:DNx, UniProtKB:G5ECN9]


organism-sequence



PR:G5ECN9-3

neuroendocrine convertase 2 isoform c (worm)

PCSK2/iso:c (worm)


"A neuroendocrine convertase 2 (worm) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:G5ECN9-3." [PRO:DNx, UniProtKB:G5ECN9]


organism-gene



PR:P16519

neuroendocrine convertase 2 (human)

hPCSK2


"A neuroendocrine convertase 2 that is encoded in the genome of human." [PRO:DNx, UniProtKB:P16519]


organism-sequence



PR:P16519-1

neuroendocrine convertase 2 isoform h1 (human)

hPCSK2/iso:h1


"A neuroendocrine convertase 2 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P16519-1." [PRO:DNx, UniProtKB:P16519]


organism-sequence



PR:P16519-2

neuroendocrine convertase 2 isoform h2 (human)

hPCSK2/iso:h2


"A neuroendocrine convertase 2 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P16519-2." [PRO:DNx, UniProtKB:P16519]


organism-sequence



PR:P16519-3

neuroendocrine convertase 2 isoform h3 (human)

hPCSK2/iso:h3


"A neuroendocrine convertase 2 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P16519-3." [PRO:DNx, UniProtKB:P16519]


organism-modification



PR:000073554

neuroendocrine convertase 2, mature form (human)

hPCSK2/mature


"A neuroendocrine convertase 2 (human) that has had the signal peptide and propeptide removed. Example: UniProtKB:P16519-1, 110-638." [PRO:DNx, Reactome:R-HSA-265156]


organism-modification



PR:000083080

neuroendocrine convertase 2 deaminated 1 (human)

hPCSK2/Deam:1


"A neuroendocrine convertase 2 (human) that has been deaminated on the residue at the position equivalent to Asn-192 of the amino acid sequence represented by UniProtKB:P16519-1. Example: UniProtKB:P16519-1, Asn-192, MOD:00684." [IEDB_epitope:1625815, PRO:DNx]


organism-gene



PR:P21661

neuroendocrine convertase 2 (mouse)

mPCSK2


"A neuroendocrine convertase 2 that is encoded in the genome of mouse." [OMA:P21661, PRO:DNx]


organism-sequence



PR:P21661-1

neuroendocrine convertase 2 isoform 1 (mouse)

mPCSK2/iso:1


"A neuroendocrine convertase 2 isoform 1 that is encoded in the genome of mouse." [PRO:DNx]


organism-gene



PR:P28841

neuroendocrine convertase 2 (rat)

rPCSK2


"A neuroendocrine convertase 2 that is encoded in the genome of rat." [OMA:P28841, PRO:DNx]


organism-sequence



PR:P28841-1

neuroendocrine convertase 2 isoform 1 (rat)

rPCSK2/iso:1


"A neuroendocrine convertase 2 isoform 1 that is encoded in the genome of rat." [PRO:DNx]


organism-modification



PR:000058870

neuroendocrine convertase 2 N-glycosylated 1 (rat)

rPCSK2/NGlyco:1


"A neuroendocrine convertase 2 (rat) that has been N-glycosylated at the residue equivalent to Asn-523 of the amino acid sequence represented by UniProtKB:P28841-1, in which the glycan structure is represented by GlyTouCan:G09775CH. Example: UniProtKB:P28841-1, Asn-523, MOD:00160~GNO:G09775CH." [GlyGen:P28841-1, PMID:24090084, PRO:DNx]


organism-modification



PR:000058871

neuroendocrine convertase 2 N-glycosylated 2 (rat)

rPCSK2/NGlyco:2


"A neuroendocrine convertase 2 (rat) that has been N-glycosylated at the residue equivalent to Asn-523 of the amino acid sequence represented by UniProtKB:P28841-1, in which the glycan composition is represented by GlyTouCan:G31852PQ. Example: UniProtKB:P28841-1, Asn-523, MOD:00160~GNO:G31852PQ." [GlyGen:P28841-1, PMID:24090084, PRO:DNx]


organism-modification



PR:000058872

neuroendocrine convertase 2 N-glycosylated 3 (rat)

rPCSK2/NGlyco:3


"A neuroendocrine convertase 2 (rat) that has been N-glycosylated at the residue equivalent to Asn-523 of the amino acid sequence represented by UniProtKB:P28841-1, in which the glycan structure is represented by GlyTouCan:G37135JQ. Example: UniProtKB:P28841-1, Asn-523, MOD:00160~GNO:G37135JQ." [GlyGen:P28841-1, PMID:24090084, PRO:DNx]


organism-modification



PR:000058873

neuroendocrine convertase 2 N-glycosylated 4 (rat)

rPCSK2/NGlyco:4


"A neuroendocrine convertase 2 (rat) that has been N-glycosylated at the residue equivalent to Asn-523 of the amino acid sequence represented by UniProtKB:P28841-1, in which the glycan composition is represented by GlyTouCan:G41247ZX. Example: UniProtKB:P28841-1, Asn-523, MOD:00160~GNO:G41247ZX." [GlyGen:P28841-1, PMID:24090084, PRO:DNx]


organism-modification



PR:000058874

neuroendocrine convertase 2 N-glycosylated 5 (rat)

rPCSK2/NGlyco:5


"A neuroendocrine convertase 2 (rat) that has been N-glycosylated at the residue equivalent to Asn-523 of the amino acid sequence represented by UniProtKB:P28841-1, in which the glycan structure is represented by GlyTouCan:G80966KZ. Example: UniProtKB:P28841-1, Asn-523, MOD:00160~GNO:G80966KZ." [GlyGen:P28841-1, PMID:24090084, PRO:DNx]


organism-gene



PR:Q9VBC7

neuroendocrine convertase 2 (fruit fly)

fly-PCSK2


"A neuroendocrine convertase 2 that is encoded in the genome of fruit fly." [OMA:Q9VBC7, PRO:DNx]


sequence



PR:000039057

neuroendocrine convertase 2 isoform 1

PCSK2/iso:1


"A neuroendocrine convertase 2 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P21661-1 or a 1:1 ortholog thereof." [PRO:DNx]


organism-sequence



PR:P21661-1

neuroendocrine convertase 2 isoform 1 (mouse)

mPCSK2/iso:1


"A neuroendocrine convertase 2 isoform 1 that is encoded in the genome of mouse." [PRO:DNx]


organism-sequence



PR:P28841-1

neuroendocrine convertase 2 isoform 1 (rat)

rPCSK2/iso:1


"A neuroendocrine convertase 2 isoform 1 that is encoded in the genome of rat." [PRO:DNx]


gene



PR:000012436

proprotein convertase subtilisin/kexin type 4

PCSK4


"A subtilisin/kexin-type proprotein convertase that is a translation product of the human PCSK4 gene or a 1:1 ortholog thereof." [PRO:DNx]


organism-gene



PR:P29121

proprotein convertase subtilisin/kexin type 4 (mouse)

mPCSK4


"A proprotein convertase subtilisin/kexin type 4 that is encoded in the genome of mouse." [OMA:P29121, PRO:DNx]


organism-sequence



PR:P29121-1

proprotein convertase subtilisin/kexin type 4 isoform m1 (mouse)

mPCSK4/iso:m1


"A proprotein convertase subtilisin/kexin type 4 (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P29121-1." [PRO:DNx, UniProtKB:P29121]


organism-sequence



PR:P29121-2

proprotein convertase subtilisin/kexin type 4 isoform m2 (mouse)

mPCSK4/iso:m2


"A proprotein convertase subtilisin/kexin type 4 (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P29121-2." [PRO:DNx, UniProtKB:P29121]


organism-sequence



PR:P29121-3

proprotein convertase subtilisin/kexin type 4 isoform 3 (mouse)

mPCSK4/iso:3


"A proprotein convertase subtilisin/kexin type 4 isoform 3 that is encoded in the genome of mouse." [PRO:DNx]


organism-sequence



PR:P29121-4

proprotein convertase subtilisin/kexin type 4 isoform 4 (mouse)

mPCSK4/iso:4


"A proprotein convertase subtilisin/kexin type 4 isoform 4 that is encoded in the genome of mouse." [PRO:DNx]


organism-sequence



PR:P29121-5

proprotein convertase subtilisin/kexin type 4 isoform m5 (mouse)

mPCSK4/iso:m5


"A proprotein convertase subtilisin/kexin type 4 (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P29121-5." [PRO:DNx, UniProtKB:P29121]


organism-sequence



PR:P29121-6

proprotein convertase subtilisin/kexin type 4 isoform m6 (mouse)

mPCSK4/iso:m6


"A proprotein convertase subtilisin/kexin type 4 (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P29121-6." [PRO:DNx, UniProtKB:P29121]


organism-sequence



PR:P29121-7

proprotein convertase subtilisin/kexin type 4 isoform m7 (mouse)

mPCSK4/iso:m7


"A proprotein convertase subtilisin/kexin type 4 (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P29121-7." [PRO:DNx, UniProtKB:P29121]


organism-sequence



PR:P29121-8

proprotein convertase subtilisin/kexin type 4 isoform m8 (mouse)

mPCSK4/iso:m8


"A proprotein convertase subtilisin/kexin type 4 (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P29121-8." [PRO:DNx, UniProtKB:P29121]


organism-gene



PR:P51559

endoprotease bli-4 (worm)

PCSK4 (worm)


"A proprotein convertase subtilisin/kexin type 4 that is encoded in the genome of worm." [PRO:DNx]


organism-sequence



PR:P51559-10

endoprotease bli-4 isoform f (worm)

PCSK4/iso:f (worm)


"An endoprotease bli-4 (worm) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P51559-10." [PRO:DNx, UniProtKB:P51559]


organism-sequence



PR:P51559-11

endoprotease bli-4 isoform g (worm)

PCSK4/iso:g (worm)


"An endoprotease bli-4 (worm) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P51559-11." [PRO:DNx, UniProtKB:P51559]


organism-sequence



PR:P51559-12

endoprotease bli-4 isoform h (worm)

PCSK4/iso:h (worm)


"An endoprotease bli-4 (worm) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P51559-12." [PRO:DNx, UniProtKB:P51559]


organism-sequence



PR:P51559-13

endoprotease bli-4 isoform i (worm)

PCSK4/iso:i (worm)


"An endoprotease bli-4 (worm) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P51559-13." [PRO:DNx, UniProtKB:P51559]


organism-sequence



PR:P51559-14

endoprotease bli-4 isoform j (worm)

PCSK4/iso:j (worm)


"An endoprotease bli-4 (worm) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P51559-14." [PRO:DNx, UniProtKB:P51559]


organism-sequence



PR:P51559-15

endoprotease bli-4 isoform d (worm)

PCSK4/iso:d (worm)


"An endoprotease bli-4 (worm) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P51559-15." [PRO:DNx, UniProtKB:P51559]


organism-sequence



PR:P51559-6

endoprotease bli-4 isoform a (worm)

PCSK4/iso:a (worm)


"An endoprotease bli-4 (worm) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P51559-6." [PRO:DNx, UniProtKB:P51559]


organism-sequence



PR:P51559-7

endoprotease bli-4 isoform b (worm)

PCSK4/iso:b (worm)


"An endoprotease bli-4 (worm) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P51559-7." [PRO:DNx, UniProtKB:P51559]


organism-sequence



PR:P51559-8

endoprotease bli-4 isoform c (worm)

PCSK4/iso:c (worm)


"An endoprotease bli-4 (worm) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P51559-8." [PRO:DNx, UniProtKB:P51559]


organism-sequence



PR:P51559-9

endoprotease bli-4 isoform e (worm)

PCSK4/iso:e (worm)


"An endoprotease bli-4 (worm) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P51559-9." [PRO:DNx, UniProtKB:P51559]


organism-gene



PR:Q6UW60

proprotein convertase subtilisin/kexin type 4 (human)

hPCSK4


"A proprotein convertase subtilisin/kexin type 4 that is encoded in the genome of human." [PRO:DNx, UniProtKB:Q6UW60]


organism-sequence



PR:Q6UW60-1

proprotein convertase subtilisin/kexin type 4 isoform h1 (human)

hPCSK4/iso:h1


"A proprotein convertase subtilisin/kexin type 4 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q6UW60-1." [PRO:DNx, UniProtKB:Q6UW60]


organism-sequence



PR:Q6UW60-2

proprotein convertase subtilisin/kexin type 4 isoform h2 (human)

hPCSK4/iso:h2


"A proprotein convertase subtilisin/kexin type 4 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q6UW60-2." [PRO:DNx, UniProtKB:Q6UW60]


organism-gene



PR:Q78EH2

proprotein convertase subtilisin/kexin type 4 (rat)

rPCSK4


"A proprotein convertase subtilisin/kexin type 4 that is encoded in the genome of rat." [OMA:Q78EH2, PRO:DNx]


organism-sequence



PR:Q78EH2-1

proprotein convertase subtilisin/kexin type 4 isoform r1 (rat)

rPCSK4/iso:r1


"A proprotein convertase subtilisin/kexin type 4 (rat) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q78EH2-1." [PRO:DNx, UniProtKB:Q78EH2]


organism-sequence



PR:Q78EH2-2

proprotein convertase subtilisin/kexin type 4 isoform r2 (rat)

rPCSK4/iso:r2


"A proprotein convertase subtilisin/kexin type 4 (rat) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q78EH2-2." [PRO:DNx, UniProtKB:Q78EH2]


organism-sequence



PR:Q78EH2-3

proprotein convertase subtilisin/kexin type 4 isoform r3 (rat)

rPCSK4/iso:r3


"A proprotein convertase subtilisin/kexin type 4 (rat) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q78EH2-3." [PRO:DNx, UniProtKB:Q78EH2]


organism-sequence



PR:Q78EH2-4

proprotein convertase subtilisin/kexin type 4 isoform 4 (rat)

rPCSK4/iso:4


"A proprotein convertase subtilisin/kexin type 4 isoform 3 that is encoded in the genome of rat." [PRO:DNx]


organism-sequence



PR:Q78EH2-5

proprotein convertase subtilisin/kexin type 4 isoform 5 (rat)

rPCSK4/iso:5


"A proprotein convertase subtilisin/kexin type 4 isoform 4 that is encoded in the genome of rat." [PRO:DNx]


sequence



PR:000039211

proprotein convertase subtilisin/kexin type 4 isoform 3

PCSK4/iso:3


"A proprotein convertase subtilisin/kexin type 4 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P29121-3 or a 1:1 ortholog thereof." [PRO:DNx]


organism-sequence



PR:P29121-3

proprotein convertase subtilisin/kexin type 4 isoform 3 (mouse)

mPCSK4/iso:3


"A proprotein convertase subtilisin/kexin type 4 isoform 3 that is encoded in the genome of mouse." [PRO:DNx]


organism-sequence



PR:Q78EH2-4

proprotein convertase subtilisin/kexin type 4 isoform 4 (rat)

rPCSK4/iso:4


"A proprotein convertase subtilisin/kexin type 4 isoform 3 that is encoded in the genome of rat." [PRO:DNx]


sequence



PR:000039212

proprotein convertase subtilisin/kexin type 4 isoform 4

PCSK4/iso:4


"A proprotein convertase subtilisin/kexin type 4 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P29121-4 or a 1:1 ortholog thereof." [PRO:DNx]


organism-sequence



PR:P29121-4

proprotein convertase subtilisin/kexin type 4 isoform 4 (mouse)

mPCSK4/iso:4


"A proprotein convertase subtilisin/kexin type 4 isoform 4 that is encoded in the genome of mouse." [PRO:DNx]


organism-sequence



PR:Q78EH2-5

proprotein convertase subtilisin/kexin type 4 isoform 5 (rat)

rPCSK4/iso:5


"A proprotein convertase subtilisin/kexin type 4 isoform 4 that is encoded in the genome of rat." [PRO:DNx]


gene



PR:000012437

proprotein convertase subtilisin/kexin type 5

PCSK5


"A subtilisin/kexin-type proprotein convertase that is a translation product of the human PCSK5 gene or a 1:1 ortholog thereof." [PRO:DNx]


organism-gene



PR:P30432

furin-like protease 2 (fruit fly)

fly-PCSK5


"A proprotein convertase subtilisin/kexin type 5 that is encoded in the genome of fruit fly." [PRO:DNx]


organism-sequence



PR:P30432-1

furin-like protease 2 isoform D (fruit fly)

fly-PCSK5/iso:D


"A furin-like protease 2 (fruit fly) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P30432-1." [PRO:DNx, UniProtKB:P30432]


organism-sequence



PR:P30432-2

furin-like protease 2 isoform A (fruit fly)

fly-PCSK5/iso:A


"A furin-like protease 2 (fruit fly) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P30432-2." [PRO:DNx, UniProtKB:P30432]


organism-gene



PR:P41413

proprotein convertase subtilisin/kexin type 5 (rat)

rPCSK5


"A proprotein convertase subtilisin/kexin type 5 that is encoded in the genome of rat." [OMA:P41413, PRO:DNx]


organism-sequence



PR:P41413-1

proprotein convertase subtilisin/kexin type 5 isoform rPC5B (rat)

rPCSK5/iso:rPC5B


"A proprotein convertase subtilisin/kexin type 5 (rat) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P41413-1." [PRO:DNx, UniProtKB:P41413]


organism-sequence



PR:P41413-2

proprotein convertase subtilisin/kexin type 5 isoform rPC5A (rat)

rPCSK5/iso:rPC5A


"A proprotein convertase subtilisin/kexin type 5 (rat) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P41413-2." [PRO:DNx, UniProtKB:P41413]


organism-gene



PR:Q04592

proprotein convertase subtilisin/kexin type 5 (mouse)

mPCSK5


"A proprotein convertase subtilisin/kexin type 5 that is encoded in the genome of mouse." [OMA:Q04592, PRO:DNx]


organism-sequence



PR:Q04592-1

proprotein convertase subtilisin/kexin type 5 isoform PC5B (mouse)

mPCSK5/iso:PC5B


"A proprotein convertase subtilisin/kexin type 5 (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q04592-1." [PMID:8335106, PRO:HJD, UniProtKB:Q04592]

Yes

organism-sequence



PR:Q04592-2

proprotein convertase subtilisin/kexin type 5 isoform PC5A (mouse)

mPCSK5/iso:PC5A


"A proprotein convertase subtilisin/kexin type 5 (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q04592-2." [PMID:8468318, PRO:HJD, UniProtKB:Q04592]

Yes

organism-gene



PR:Q92824

proprotein convertase subtilisin/kexin type 5 (human)

hPCSK5


"A proprotein convertase subtilisin/kexin type 5 that is encoded in the genome of human." [PRO:DNx, UniProtKB:Q92824]


organism-sequence



PR:Q92824-1

proprotein convertase subtilisin/kexin type 5 isoform hPC6B (human)

hPCSK5/iso:hPC6B


"A proprotein convertase subtilisin/kexin type 5 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q92824-1." [PRO:DNx, UniProtKB:Q92824]


organism-sequence



PR:Q92824-2

proprotein convertase subtilisin/kexin type 5 isoform hPC6A (human)

hPCSK5/iso:hPC6A


"A proprotein convertase subtilisin/kexin type 5 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q92824-2." [PRO:DNx, UniProtKB:Q92824]


modification



PR:000020887

proprotein convertase subtilisin/kexin type 5, signal peptide removed form

PCSK5/SigPep-


"A proprotein convertase subtilisin/kexin type 5 that has had the signal peptide removed." [PRO:DNx]


modification



PR:000020888

proprotein convertase subtilisin/kexin type 5 proteolytic cleavage product

PCSK5/ClvPrd


"A proprotein convertase subtilisin/kexin type 5 that has been processed by proteolytic cleavage." [PRO:DNx]


gene



PR:000012438

proprotein convertase subtilisin/kexin type 6

PCSK6


"A subtilisin/kexin-type proprotein convertase that is a translation product of the human PCSK6 gene or a 1:1 ortholog thereof." [PRO:DNx]


organism-gene



PR:P29122

proprotein convertase subtilisin/kexin type 6 (human)

hPCSK6


"A proprotein convertase subtilisin/kexin type 6 that is encoded in the genome of human." [PRO:DNx, UniProtKB:P29122]


organism-sequence



PR:P29122-1

proprotein convertase subtilisin/kexin type 6 isoform hPACE4A-I (human)

hPCSK6/iso:hPACE4A-I


"A proprotein convertase subtilisin/kexin type 6 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P29122-1." [PRO:DNx, UniProtKB:P29122]


organism-sequence



PR:P29122-2

proprotein convertase subtilisin/kexin type 6 isoform hPACE4A-II (human)

hPCSK6/iso:hPACE4A-II


"A proprotein convertase subtilisin/kexin type 6 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P29122-2." [PRO:DNx, UniProtKB:P29122]


organism-sequence



PR:P29122-3

proprotein convertase subtilisin/kexin type 6 isoform hPACE4B (human)

hPCSK6/iso:hPACE4B


"A proprotein convertase subtilisin/kexin type 6 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P29122-3." [PRO:DNx, UniProtKB:P29122]


organism-sequence



PR:P29122-4

proprotein convertase subtilisin/kexin type 6 isoform hPACE4C (human)

hPCSK6/iso:hPACE4C


"A proprotein convertase subtilisin/kexin type 6 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P29122-4." [PRO:DNx, UniProtKB:P29122]


organism-sequence



PR:P29122-5

proprotein convertase subtilisin/kexin type 6 isoform hPACE4CS (human)

hPCSK6/iso:hPACE4CS


"A proprotein convertase subtilisin/kexin type 6 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P29122-5." [PRO:DNx, UniProtKB:P29122]


organism-sequence



PR:P29122-6

proprotein convertase subtilisin/kexin type 6 isoform hPACE4D (human)

hPCSK6/iso:hPACE4D


"A proprotein convertase subtilisin/kexin type 6 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P29122-6." [PRO:DNx, UniProtKB:P29122]


organism-sequence



PR:P29122-7

proprotein convertase subtilisin/kexin type 6 isoform hPACE4E-I (human)

hPCSK6/iso:hPACE4E-I


"A proprotein convertase subtilisin/kexin type 6 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P29122-7." [PRO:DNx, UniProtKB:P29122]


organism-sequence



PR:P29122-8

proprotein convertase subtilisin/kexin type 6 isoform hPACE4E-II (human)

hPCSK6/iso:hPACE4E-II


"A proprotein convertase subtilisin/kexin type 6 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P29122-8." [PRO:DNx, UniProtKB:P29122]


organism-modification



PR:000056328

proprotein convertase subtilisin/kexin type 6 O-glycosylated 1 (human)

hPCSK6/OGlyco:1


"A proprotein convertase subtilisin/kexin type 6 (human) that has been O-glycosylated at the residue equivalent to Thr-683 of the amino acid sequence represented by UniProtKB:P29122-1, in which the glycan composition is represented by GlyTouCan:G43417UB. Example: UniProtKB:P29122-1, Thr-683, MOD:00005~GNO:G43417UB." [GlyGen:P29122-1, PMID:30459171, PRO:DNx]


organism-modification



PR:000075312

proprotein convertase subtilisin/kexin type 6, mature form (human)

hPCSK6/mature


"A proprotein convertase subtilisin/kexin type 6 (human) that has had the signal peptide and propeptide removed. Example: UniProtKB:P29122-1, 150-969." [PRO:DNx, Reactome:R-HSA-1181107, Reactome:R-HSA-3009047, Reactome:R-HSA-8849792]


organism-gene



PR:Q63415

proprotein convertase subtilisin/kexin type 6 (rat)

rPCSK6


"A proprotein convertase subtilisin/kexin type 6 that is encoded in the genome of rat." [OMA:Q63415, PRO:DNx]


modification



PR:000020889

proprotein convertase subtilisin/kexin type 6 proteolytic cleavage product

PCSK6/ClvPrd


"A proprotein convertase subtilisin/kexin type 6 that has been processed by proteolytic cleavage." [PRO:DNx]


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Functional Annotation (PRO-centric view) Switch to GO Centric View   
PRO Term GO Annotation Evidence
PR:Q04592-1 mPCSK5/iso:PC5B located_inGO:0005794 Golgi apparatus MGI_ref:84424; PMID:8947550
PR:Q04592-2 mPCSK5/iso:PC5A located_inGO:0030141 secretory granule MGI_ref:84424; PMID:8947550