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Protein Ontology report - mitogen-activated protein kinase kinase kinase 7
PR:000003158 - http://purl.obolibrary.org/obo/PR_000003158
 
  Protein Forms  Complex      
Ontology Information Show OBO stanza
  PRO ID
PR:000003158   
  PRO namemitogen-activated protein kinase kinase kinase 7 
  Synonyms
PRO-Short-label: EXACT:MAP3K7
Gene-based: RELATED:TAK1
Other: EXACT:TGF-beta-activated kinase 1 | transforming growth factor-beta-activated kinase 1
  Definition"A protein that is a translation product of the human MAP3K7 gene or a 1:1 ortholog thereof." [PRO:CNA] 
  PRO Categorygene 
  ParentPR:000000001 protein
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Gene1                                                  Organism-Gene 4                                        
         Sequence1                                                  Organism-Sequence 5                                        
         Modification3                                                  Organism-Modification 8                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Related Cross References

  Db identifiers
PIRSF:PIRSF038168;IUPHARobj:2082
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Protein Forms  Switch to Extended View   

Category  
PRO Form Name
Short Name
Ann. Has Annotation?

Comp. In Complex?
gene


PR:000003158 mitogen-activated protein kinase kinase kinase 7
MAP3K7

organism-gene


PR:O43318 mitogen-activated protein kinase kinase kinase 7 (human)
hMAP3K7

Yes
organism-sequence


PR:O43318-1 mitogen-activated protein kinase kinase kinase 7 isoform h1B (human)
hMAP3K7/iso:h1B

organism-sequence


PR:O43318-2 mitogen-activated protein kinase kinase kinase 7 isoform 1A (human)
hMAP3K7/iso:1A

organism-sequence


PR:O43318-3 mitogen-activated protein kinase kinase kinase 7 isoform h1C (human)
hMAP3K7/iso:h1C

organism-sequence


PR:O43318-4 mitogen-activated protein kinase kinase kinase 7 isoform h1D (human)
hMAP3K7/iso:h1D

organism-modification


PR:000048308 mitogen-activated protein kinase kinase kinase 7 phosphorylated form (human)
hMAP3K7/PhosRes+

organism-modification


PR:000035736 mitogen-activated protein kinase kinase kinase 7 phosphorylated 1 (human)
hMAP3K7/Phos:1

Yes
organism-modification


PR:000048307 mitogen-activated protein kinase kinase kinase 7 phosphorylated 2 (human)
hMAP3K7/Phos:2

organism-modification


PR:000064767 mitogen-activated protein kinase kinase kinase 7 phosphorylated and ubiquitinated 1 (human)
hMAP3K7/PhosUbiq:1

organism-modification


PR:000048310 mitogen-activated protein kinase kinase kinase 7 ubiquitinated form (human)
hMAP3K7/UbiqLys+

organism-modification


PR:000048309 mitogen-activated protein kinase kinase kinase 7 ubiquitinated 1 (human)
hMAP3K7/Ubiq:1

organism-modification


PR:000064767 mitogen-activated protein kinase kinase kinase 7 phosphorylated and ubiquitinated 1 (human)
hMAP3K7/PhosUbiq:1

organism-modification


PR:000072531 mitogen-activated protein kinase kinase kinase 7 methylated 1 (human)
hMAP3K7/Me:1

organism-gene


PR:P0C8E4 mitogen-activated protein kinase kinase kinase 7 (rat)
rMAP3K7

organism-gene


PR:Q62073 mitogen-activated protein kinase kinase kinase 7 (mouse)
mMAP3K7

Yes
organism-sequence


PR:Q62073-1 mitogen-activated protein kinase kinase kinase 7 isoform 1 (mouse)
mMAP3K7/iso:1

organism-modification


PR:000045971 mitogen-activated protein kinase kinase kinase 7 phosphorylated 1 (mouse)
mMAP3K7/Phos:1

organism-gene


PR:Q8RX66 serine/threonine-protein kinase Nek3 (Arabidopsis thaliana)
At-MAP3K7

sequence


PR:000003159 mitogen-activated protein kinase kinase kinase 7 isoform 1
MAP3K7/iso:1

organism-sequence


PR:O43318-2 mitogen-activated protein kinase kinase kinase 7 isoform 1A (human)
hMAP3K7/iso:1A

organism-sequence


PR:Q62073-1 mitogen-activated protein kinase kinase kinase 7 isoform 1 (mouse)
mMAP3K7/iso:1

modification


PR:000003161 mitogen-activated protein kinase kinase kinase 7 isoform 1 ubiquitinated form
MAP3K7/iso:1/UbiqLys+

modification


PR:000003162 mitogen-activated protein kinase kinase kinase 7 isoform 1 ubiquitinated 1
MAP3K7/iso:1/Ubiq:1

modification


PR:000035735 mitogen-activated protein kinase kinase kinase 7 phosphorylated 1
MAP3K7/Phos:1

organism-modification


PR:000035736 mitogen-activated protein kinase kinase kinase 7 phosphorylated 1 (human)
hMAP3K7/Phos:1

Yes
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MAP3K7 forms found in complexes   

MAP3K7 Component
 Complexes
PR:000035736 hMAP3K7/Phos:1 PR:000035738 free K63-linked pUb:activated TAK1 complex:pUbtraf6:ticam1:ticam2:activated TLR4 complex (human)
PR:000035740 free K63-linked pUb:activated TAK1 complex:pUbtraf6 complex (human)
PR:000037338 free K63-linked pUb:activated TAK1 complex:pUbtraf6:ticam1:activated TLR3 complex (human)
PR:O43318 hMAP3K7 PR:000028440 TAB2/TAK1 complex (human)
PR:000035730 TAK1 kinase complex (human)
PR:000035734 free K63-linked pUb:TAK1complex:pUbtraf6:ticam1:ticam2:activated TLR4 complex (human)
PR:000037342 free K63-linked pUb:TAK1complex:pUbtraf6:ticam1:activated TLR3 complex (human)
PR:Q62073 mMAP3K7 PR:000027102 TAK1 kinase complex (mouse)
PR:000027105 TRIKA2 complex (mouse)
PR:000036111 K63-poly-Ub-rip1:traf6:TAK1 kinase complex (mouse)
PR:000036114 IkappaB kinase:K63-poly-Ub-rip1:traf6:TAK1 kinase complex (mouse)
PR:000036117 pIKBK:K63-poly-Ub-rip1:traf6:TAK1 kinase complex (mouse)