|
|
 |
|
| | |
| | | | | | | |
gene
|
|
PR:000003244 |
RAF proto-oncogene serine/threonine-protein kinase
|
RAF1
|
"A protein that is a translation product of the human RAF1 gene or a 1:1 ortholog thereof." [PRO:CNA]
|
|
|
|
|
|
|
| | | | |
| | | | | |
organism-gene
|
|
PR:O94235 |
serine/threonine-protein kinase mph1 (Schizosaccharomyces pombe 972h-)
|
Spom972h-RAF1
|
"A RAF proto-oncogene serine/threonine-protein kinase that is encoded in the genome of Schizosaccharomyces pombe 972h-." [OMA:O94235, PRO:DNx]
|
|
|
|
|
|
|
| | | | |
| | | | | |
organism-gene
|
|
PR:P04049 |
RAF proto-oncogene serine/threonine-protein kinase (human)
|
hRAF1
|
"A RAF proto-oncogene serine/threonine-protein kinase that is encoded in the genome of human." [PMID:20703093, PRO:KER]
|
Yes |
|
|
|
|
|
| | | | | | |
| | | |
organism-sequence
|
|
PR:P04049-1 |
RAF proto-oncogene serine/threonine-protein kinase isoform 1 (human)
|
hRAF1/iso:1
|
"A RAF proto-oncogene serine/threonine-protein kinase isoform 1 that is encoded in the genome of human." [PRO:CNA]
|
|
|
|
|
|
|
| | | | | | | | |
| |
organism-modification
|
|
PR:000026210 |
RAF proto-oncogene serine/threonine-protein kinase isoform 1 phosphorylated 3 (human)
|
hRAF1/iso:1/Phos:3
|
"A RAF proto-oncogene serine/threonine-protein kinase isoform 1 phosphorylated 3 in human. UniProtKB:P04049-1, Ser-259/Ser-621, MOD:00046." [PMID:14688280, PRO:CNA]
|
|
|
|
|
|
|
| | | | | | | | |
| |
organism-modification
|
|
PR:000036643 |
RAF proto-oncogene serine/threonine-protein kinase isoform 1 phosphorylated 2 (human)
|
hRAF1/iso:1/Phos:2
|
"A RAF proto-oncogene serine/threonine-protein kinase isoform 1 phosphorylated 2 in human. UniProtKB:P04049-1, Ser-338/Ser-339, MOD:00046." [PMID:15849194, PRO:JAN]
|
Yes |
|
|
|
|
|
| | | | | | |
| | | |
organism-sequence
|
|
PR:P04049-2 |
RAF proto-oncogene serine/threonine-protein kinase isoform 2 (human)
|
hRAF1/iso:2
|
"A RAF proto-oncogene serine/threonine-protein kinase isoform 2 that is encoded in the genome of human." [PRO:CNA]
|
|
|
|
|
|
|
| | | | | | |
| | | |
organism-modification
|
|
PR:000045631 |
RAF proto-oncogene serine/threonine-protein kinase phosphorylated 1 (human)
|
hRAF1/Phos:1
|
"A RAF proto-oncogene serine/threonine-protein kinase (human) that has been phosphorylated on the residue at the position equivalent to Thr-269 of the amino acid sequence represented by UniProtKB:P04049-1. Example: UniProtKB:P04049-1, Thr-269, MOD:00047." [iPTMnet:P04049, PMID:7477354]
|
|
|
|
|
|
|
| | | | | | |
| | | |
organism-modification
|
|
PR:000048997 |
RAF proto-oncogene serine/threonine-protein kinase phosphorylated 3 (human)
|
hRAF1/Phos:3
|
"A RAF proto-oncogene serine/threonine-protein kinase (human) that has been post-translationally modified to include phosphoserine at positions 259 and 621 of the amino acid sequence represented by UniProtKB:P04049. UniProtKB:P04049, Ser-259/Ser-621, MOD:00046." [PRO:DNx, Reactome:R-HSA-109786]
|
|
|
|
|
|
|
| | | | | | |
| | | |
organism-modification
|
|
PR:000048998 |
RAF proto-oncogene serine/threonine-protein kinase phosphorylated 4 (human)
|
hRAF1/Phos:4
|
"A RAF proto-oncogene serine/threonine-protein kinase (human) that has been post-translationally modified to include phosphoserine at positions 29, 43, 259, 296, 301, 338, 494, 621 and 642, phosphotyrosine at position 341, and phosphothreonine at position 491 of the amino acid sequence represented by UniProtKB:P04049. UniProtKB:P04049, Ser-29/Ser-43/Ser-259/Ser-296/Ser-301/Ser-338/Ser-494/Ser-621/Ser-642, MOD:00046|Tyr-341, MOD:00048|Thr-491, MOD:00047." [PRO:DNx, Reactome:R-HSA-5675193]
|
|
|
|
|
|
|
| | | | | | |
| | | |
organism-modification
|
|
PR:000048999 |
RAF proto-oncogene serine/threonine-protein kinase phosphorylated 5 (human)
|
hRAF1/Phos:5
|
"A RAF proto-oncogene serine/threonine-protein kinase (human) that has been phosphorylated on the residue at the position equivalent to Ser-338 of the amino acid sequence represented by UniProtKB:P04049. UniProtKB:P04049, Ser-338, MOD:00046." [PRO:DNx, Reactome:R-HSA-5624469]
|
|
|
|
|
|
|
| | | | | | |
| | | |
organism-modification
|
|
PR:000049000 |
RAF proto-oncogene serine/threonine-protein kinase phosphorylated 6 (human)
|
hRAF1/Phos:6
|
"A RAF proto-oncogene serine/threonine-protein kinase (human) that has been phosphorylated on the residue at the position equivalent to Ser-338, and phosphotyrosine at positions 340 and 341 of the amino acid sequence represented by UniProtKB:P04049. UniProtKB:P04049, Ser-338, MOD:00046|Tyr-340/Tyr-341, MOD:00048." [PRO:DNx, Reactome:R-HSA-5624465]
|
|
|
|
|
|
|
| | | | | | |
| | | |
organism-modification
|
|
PR:000049001 |
RAF proto-oncogene serine/threonine-protein kinase phosphorylated 7 (human)
|
hRAF1/Phos:7
|
"A RAF proto-oncogene serine/threonine-protein kinase (human) that has been post-translationally modified to include phosphoserine at positions 338, 494 and 621, phosphotyrosine at position 341, and phosphothreonine at position 491 of the amino acid sequence represented by UniProtKB:P04049. UniProtKB:P04049, Ser-338/Ser-494/Ser-621, MOD:00046|Tyr-341, MOD:00048|Thr-491, MOD:00047." [PRO:DNx, Reactome:R-HSA-5672664, Reactome:R-HSA-5672665]
|
|
|
|
|
|
|
| | | | | | |
| | | |
organism-modification
|
|
PR:000049002 |
RAF proto-oncogene serine/threonine-protein kinase phosphorylated 8 (human)
|
hRAF1/Phos:8
|
"A RAF proto-oncogene serine/threonine-protein kinase (human) that has been phosphorylated on the residue at the position equivalent to Ser-621 of the amino acid sequence represented by UniProtKB:P04049. UniProtKB:P04049, Ser-621, MOD:00046." [PRO:DNx, Reactome:R-HSA-206028, Reactome:R-HSA-206222]
|
|
|
|
|
|
|
| | | | | | |
| | | |
organism-modification
|
|
PR:000049003 |
RAF proto-oncogene serine/threonine-protein kinase phosphorylated 9 (human)
|
hRAF1/Phos:9
|
"A RAF proto-oncogene serine/threonine-protein kinase (human) that has been phosphorylated on the residue at the position equivalent to Tyr-341, phosphothreonine at position 491, and phosphoserine at positions 494 and 621 of the amino acid sequence represented by UniProtKB:P04049. UniProtKB:P04049, Tyr-341, MOD:00048|Thr-491, MOD:00047|Ser-494/Ser-621, MOD:00046." [PRO:DNx, Reactome:R-HSA-5675420]
|
|
|
|
|
|
|
| | | | | | |
| | | |
organism-modification
|
|
PR:000060294 |
RAF proto-oncogene serine/threonine-protein kinase sequence variant V263A phosphorylated 1 (human)
|
hRAF1/var:V263A/Phos:1
|
"A RAF proto-oncogene serine/threonine-protein kinase (human) that has an Ala residue at the position equivalent to Val-263 of the amino acid sequence represented by UniProtKB:P04049-1 and that has been phosphorylated on the residues at the positions equivalent to Ser-338, Tyr-341, Thr-491, Ser-494, and Ser-621. Example: UniProtKB:P04049-1, Val-263, CHEBI:46217|Ser-338/Ser-494/Ser-621, MOD:00046|Tyr-341, MOD:00048|Thr-491, MOD:00047." [PRO:DNx, Reactome:R-HSA-9656080]
|
|
|
|
|
|
|
| | | | | | |
| | | |
organism-modification
|
|
PR:000060304 |
RAF proto-oncogene serine/threonine-protein kinase sequence variant N262L phosphorylated 1 (human)
|
hRAF1/var:N262L/Phos:1
|
"A RAF proto-oncogene serine/threonine-protein kinase (human) that has a Leu residue at the position equivalent to Asn-262 of the amino acid sequence represented by UniProtKB:P04049-1 and that has been phosphorylated on the residue at the position equivalent to Ser-621. Example: UniProtKB:P04049-1, Asn-262, CHEBI:30006|Ser-621, MOD:00046." [PRO:DNx, Reactome:R-HSA-9656101]
|
|
|
|
|
|
|
| | | | | | |
| | | |
organism-modification
|
|
PR:000060342 |
RAF proto-oncogene serine/threonine-protein kinase sequence variant L613V phosphorylated 1 (human)
|
hRAF1/var:L613V/Phos:1
|
"A RAF proto-oncogene serine/threonine-protein kinase (human) that has a Val residue at the position equivalent to Leu-613 of the amino acid sequence represented by UniProtKB:P04049-1 and that has been phosphorylated on the residues at the positions equivalent to Ser-338, Tyr-341, Thr-491, Ser-494, and Ser-621. Example: UniProtKB:P04049-1, Ser-338/Ser-494/Ser-621, MOD:00046|Tyr-341, MOD:00048|Thr-491, MOD:00047|Leu-613, CHEBI:30015." [PRO:DNx, Reactome:R-HSA-9656035]
|
|
|
|
|
|
|
| | | | | | |
| | | |
organism-modification
|
|
PR:000060487 |
RAF proto-oncogene serine/threonine-protein kinase sequence variant S259T phosphorylated 1 (human)
|
hRAF1/var:S259T/Phos:1
|
"A RAF proto-oncogene serine/threonine-protein kinase (human) that has a Thr residue at the position equivalent to Ser-259 of the amino acid sequence represented by UniProtKB:P04049-1 and that has been phosphorylated on the residues at the positions equivalent to Ser-338, Tyr-341, Thr-491, Ser-494, and Ser-621. Example: UniProtKB:P04049-1, Ser-259, CHEBI:30013|Ser-338/Ser-494/Ser-621, MOD:00046|Tyr-341, MOD:00048|Thr-491, MOD:00047." [PRO:DNx, Reactome:R-HSA-9656067]
|
|
|
|
|
|
|
| | | | | | |
| | | |
organism-modification
|
|
PR:000060534 |
RAF proto-oncogene serine/threonine-protein kinase sequence variant P261A phosphorylated 1 (human)
|
hRAF1/var:P261A/Phos:1
|
"A RAF proto-oncogene serine/threonine-protein kinase (human) that has an Ala residue at the position equivalent to Pro-261 of the amino acid sequence represented by UniProtKB:P04049-1 and that has been phosphorylated on the residue at the position equivalent to Ser-621. Example: UniProtKB:P04049-1, Pro-261, CHEBI:46217|Ser-621, MOD:00046." [PRO:DNx, Reactome:R-HSA-9656103]
|
|
|
|
|
|
|
| | | | | | |
| | | |
organism-modification
|
|
PR:000060574 |
RAF proto-oncogene serine/threonine-protein kinase sequence variant G370R phosphorylated 1 (human)
|
hRAF1/var:G370R/Phos:1
|
"A RAF proto-oncogene serine/threonine-protein kinase (human) that has an Arg residue at the position equivalent to Gly-370 of the amino acid sequence represented by UniProtKB:P04049-1 and that has been phosphorylated on the residue at the position equivalent to Ser-621. Example: UniProtKB:P04049-1, Gly-370, CHEBI:29952|Ser-621, MOD:00046." [PRO:DNx, Reactome:R-HSA-9656094]
|
|
|
|
|
|
|
| | | | | | |
| | | |
organism-modification
|
|
PR:000060735 |
RAF proto-oncogene serine/threonine-protein kinase sequence variant R256S phosphorylated 1 (human)
|
hRAF1/var:R256S/Phos:1
|
"A RAF proto-oncogene serine/threonine-protein kinase (human) that has a Ser residue at the position equivalent to Arg-256 of the amino acid sequence represented by UniProtKB:P04049-1 and that has been phosphorylated on the residues at the positions equivalent to Ser-338, Tyr-341, Thr-491, Ser-494, and Ser-621. Example: UniProtKB:P04049-1, Arg-256, CHEBI:29999|Ser-338/Ser-494/Ser-621, MOD:00046|Tyr-341, MOD:00048|Thr-491, MOD:00047." [PRO:DNx, Reactome:R-HSA-9656056]
|
|
|
|
|
|
|
| | | | | | |
| | | |
organism-modification
|
|
PR:000060783 |
RAF proto-oncogene serine/threonine-protein kinase sequence variant S427G phosphorylated 1 (human)
|
hRAF1/var:S427G/Phos:1
|
"A RAF proto-oncogene serine/threonine-protein kinase (human) that has a Gly residue at the position equivalent to Ser-427 of the amino acid sequence represented by UniProtKB:P04049-1 and that has been phosphorylated on the residues at the positions equivalent to Ser-338, Tyr-341, Thr-491, Ser-494, and Ser-621. Example: UniProtKB:P04049-1, Ser-338/Ser-494/Ser-621, MOD:00046|Tyr-341, MOD:00048|Ser-427, CHEBI:29947|Thr-491, MOD:00047." [PRO:DNx, Reactome:R-HSA-9656070]
|
|
|
|
|
|
|
| | | | | | |
| | | |
organism-modification
|
|
PR:000060875 |
RAF proto-oncogene serine/threonine-protein kinase sequence variant S427G phosphorylated 2 (human)
|
hRAF1/var:S427G/Phos:2
|
"A RAF proto-oncogene serine/threonine-protein kinase (human) that has a Gly residue at the position equivalent to Ser-427 of the amino acid sequence represented by UniProtKB:P04049-1 and that has been phosphorylated on the residue at the position equivalent to Ser-621. Example: UniProtKB:P04049-1, Ser-427, CHEBI:29947|Ser-621, MOD:00046." [PRO:DNx, Reactome:R-HSA-9656134]
|
|
|
|
|
|
|
| | | | | | |
| | | |
organism-modification
|
|
PR:000060889 |
RAF proto-oncogene serine/threonine-protein kinase sequence variant P261N phosphorylated 1 (human)
|
hRAF1/var:P261N/Phos:1
|
"A RAF proto-oncogene serine/threonine-protein kinase (human) that has an Asn residue at the position equivalent to Pro-261 of the amino acid sequence represented by UniProtKB:P04049-1 and that has been phosphorylated on the residue at the position equivalent to Ser-621. Example: UniProtKB:P04049-1, Pro-261, CHEBI:50347|Ser-621, MOD:00046." [PRO:DNx, Reactome:R-HSA-9656110]
|
|
|
|
|
|
|
| | | | | | |
| | | |
organism-modification
|
|
PR:000061147 |
RAF proto-oncogene serine/threonine-protein kinase sequence variant T260I phosphorylated 1 (human)
|
hRAF1/var:T260I/Phos:1
|
"A RAF proto-oncogene serine/threonine-protein kinase (human) that has an Ile residue at the position equivalent to Thr-260 of the amino acid sequence represented by UniProtKB:P04049-1 and that has been phosphorylated on the residue at the position equivalent to Ser-621. Example: UniProtKB:P04049-1, Thr-260, CHEBI:30009|Ser-621, MOD:00046." [PRO:DNx, Reactome:R-HSA-9656136]
|
|
|
|
|
|
|
| | | | | | |
| | | |
organism-modification
|
|
PR:000061178 |
RAF proto-oncogene serine/threonine-protein kinase sequence variant S259P phosphorylated 1 (human)
|
hRAF1/var:S259P/Phos:1
|
"A RAF proto-oncogene serine/threonine-protein kinase (human) that has a Pro residue at the position equivalent to Ser-259 of the amino acid sequence represented by UniProtKB:P04049-1 and that has been phosphorylated on the residues at the positions equivalent to Ser-338, Tyr-341, Thr-491, Ser-494, and Ser-621. Example: UniProtKB:P04049-1, Ser-259, CHEBI:50342|Ser-338/Ser-494/Ser-621, MOD:00046|Tyr-341, MOD:00048|Thr-491, MOD:00047." [PRO:DNx, Reactome:R-HSA-9656065]
|
|
|
|
|
|
|
| | | | | | |
| | | |
organism-modification
|
|
PR:000061258 |
RAF proto-oncogene serine/threonine-protein kinase sequence variant P261L phosphorylated 1 (human)
|
hRAF1/var:P261L/Phos:1
|
"A RAF proto-oncogene serine/threonine-protein kinase (human) that has a Leu residue at the position equivalent to Pro-261 of the amino acid sequence represented by UniProtKB:P04049-1 and that has been phosphorylated on the residue at the position equivalent to Ser-621. Example: UniProtKB:P04049-1, Pro-261, CHEBI:30006|Ser-621, MOD:00046." [PRO:DNx, Reactome:R-HSA-9656106]
|
|
|
|
|
|
|
| | | | | | |
| | | |
organism-modification
|
|
PR:000061438 |
RAF proto-oncogene serine/threonine-protein kinase sequence variant P261T phosphorylated 1 (human)
|
hRAF1/var:P261T/Phos:1
|
"A RAF proto-oncogene serine/threonine-protein kinase (human) that has a Thr residue at the position equivalent to Pro-261 of the amino acid sequence represented by UniProtKB:P04049-1 and that has been phosphorylated on the residue at the position equivalent to Ser-621. Example: UniProtKB:P04049-1, Pro-261, CHEBI:30013|Ser-621, MOD:00046." [PRO:DNx, Reactome:R-HSA-9656115]
|
|
|
|
|
|
|
| | | | | | |
| | | |
organism-modification
|
|
PR:000061913 |
RAF proto-oncogene serine/threonine-protein kinase sequence variant S259P phosphorylated 2 (human)
|
hRAF1/var:S259P/Phos:2
|
"A RAF proto-oncogene serine/threonine-protein kinase (human) that has a Pro residue at the position equivalent to Ser-259 of the amino acid sequence represented by UniProtKB:P04049-1 and that has been phosphorylated on the residue at the position equivalent to Ser-621. Example: UniProtKB:P04049-1, Ser-259, CHEBI:50342|Ser-621, MOD:00046." [PRO:DNx, Reactome:R-HSA-9656127]
|
|
|
|
|
|
|
| | | | | | |
| | | |
organism-modification
|
|
PR:000061916 |
RAF proto-oncogene serine/threonine-protein kinase sequence variant P261A phosphorylated 2 (human)
|
hRAF1/var:P261A/Phos:2
|
"A RAF proto-oncogene serine/threonine-protein kinase (human) that has an Ala residue at the position equivalent to Pro-261 of the amino acid sequence represented by UniProtKB:P04049-1 and that has been phosphorylated on the residues at the positions equivalent to Ser-338, Tyr-341, Thr-491, Ser-494, and Ser-621. Example: UniProtKB:P04049-1, Pro-261, CHEBI:46217|Ser-338/Ser-494/Ser-621, MOD:00046|Tyr-341, MOD:00048|Thr-491, MOD:00047." [PRO:DNx, Reactome:R-HSA-9656041]
|
|
|
|
|
|
|
| | | | | | |
| | | |
organism-modification
|
|
PR:000062212 |
RAF proto-oncogene serine/threonine-protein kinase sequence variant P261L phosphorylated 2 (human)
|
hRAF1/var:P261L/Phos:2
|
"A RAF proto-oncogene serine/threonine-protein kinase (human) that has a Leu residue at the position equivalent to Pro-261 of the amino acid sequence represented by UniProtKB:P04049-1 and that has been phosphorylated on the residues at the positions equivalent to Ser-338, Tyr-341, Thr-491, Ser-494, and Ser-621. Example: UniProtKB:P04049-1, Pro-261, CHEBI:30006|Ser-338/Ser-494/Ser-621, MOD:00046|Tyr-341, MOD:00048|Thr-491, MOD:00047." [PRO:DNx, Reactome:R-HSA-9656043]
|
|
|
|
|
|
|
| | | | | | |
| | | |
organism-modification
|
|
PR:000062247 |
RAF proto-oncogene serine/threonine-protein kinase sequence variant D486N phosphorylated 1 (human)
|
hRAF1/var:D486N/Phos:1
|
"A RAF proto-oncogene serine/threonine-protein kinase (human) that has an Asn residue at the position equivalent to Asp-486 of the amino acid sequence represented by UniProtKB:P04049-1 and that has been phosphorylated on the residues at the positions equivalent to Ser-338, Tyr-341, Thr-491, Ser-494, and Ser-621. Example: UniProtKB:P04049-1, Ser-338/Ser-494/Ser-621, MOD:00046|Tyr-341, MOD:00048|Asp-486, CHEBI:50347|Thr-491, MOD:00047." [PRO:DNx, Reactome:R-HSA-9656026]
|
|
|
|
|
|
|
| | | | | | |
| | | |
organism-modification
|
|
PR:000062287 |
RAF proto-oncogene serine/threonine-protein kinase sequence variant D486N phosphorylated 2 (human)
|
hRAF1/var:D486N/Phos:2
|
"A RAF proto-oncogene serine/threonine-protein kinase (human) that has an Asn residue at the position equivalent to Asp-486 of the amino acid sequence represented by UniProtKB:P04049-1 and that has been phosphorylated on the residue at the position equivalent to Ser-621. Example: UniProtKB:P04049-1, Asp-486, CHEBI:50347|Ser-621, MOD:00046." [PRO:DNx, Reactome:R-HSA-9656088]
|
|
|
|
|
|
|
| | | | | | |
| | | |
organism-modification
|
|
PR:000062301 |
RAF proto-oncogene serine/threonine-protein kinase sequence variant G370R phosphorylated 2 (human)
|
hRAF1/var:G370R/Phos:2
|
"A RAF proto-oncogene serine/threonine-protein kinase (human) that has an Arg residue at the position equivalent to Gly-370 of the amino acid sequence represented by UniProtKB:P04049-1 and that has been phosphorylated on the residues at the positions equivalent to Ser-338, Tyr-341, Thr-491, Ser-494, and Ser-621. Example: UniProtKB:P04049-1, Ser-338/Ser-494/Ser-621, MOD:00046|Tyr-341, MOD:00048|Gly-370, CHEBI:29952|Thr-491, MOD:00047." [PRO:DNx, Reactome:R-HSA-9656031]
|
|
|
|
|
|
|
| | | | | | |
| | | |
organism-modification
|
|
PR:000062538 |
RAF proto-oncogene serine/threonine-protein kinase sequence variant P261S phosphorylated 1 (human)
|
hRAF1/var:P261S/Phos:1
|
"A RAF proto-oncogene serine/threonine-protein kinase (human) that has a Ser residue at the position equivalent to Pro-261 of the amino acid sequence represented by UniProtKB:P04049-1 and that has been phosphorylated on the residue at the position equivalent to Ser-621. Example: UniProtKB:P04049-1, Pro-261, CHEBI:29999|Ser-621, MOD:00046." [PRO:DNx, Reactome:R-HSA-9656113]
|
|
|
|
|
|
|
| | | | | | |
| | | |
organism-modification
|
|
PR:000062644 |
RAF proto-oncogene serine/threonine-protein kinase sequence variant D486G phosphorylated 1 (human)
|
hRAF1/var:D486G/Phos:1
|
"A RAF proto-oncogene serine/threonine-protein kinase (human) that has a Gly residue at the position equivalent to Asp-486 of the amino acid sequence represented by UniProtKB:P04049-1 and that has been phosphorylated on the residue at the position equivalent to Ser-621. Example: UniProtKB:P04049-1, Asp-486, CHEBI:29947|Ser-621, MOD:00046." [PRO:DNx, Reactome:R-HSA-9656085]
|
|
|
|
|
|
|
| | | | | | |
| | | |
organism-modification
|
|
PR:000062694 |
RAF proto-oncogene serine/threonine-protein kinase sequence variant L613V phosphorylated 2 (human)
|
hRAF1/var:L613V/Phos:2
|
"A RAF proto-oncogene serine/threonine-protein kinase (human) that has a Val residue at the position equivalent to Leu-613 of the amino acid sequence represented by UniProtKB:P04049-1 and that has been phosphorylated on the residue at the position equivalent to Ser-621. Example: UniProtKB:P04049-1, Leu-613, CHEBI:30015|Ser-621, MOD:00046." [PRO:DNx, Reactome:R-HSA-9656098]
|
|
|
|
|
|
|
| | | | | | |
| | | |
organism-modification
|
|
PR:000062754 |
RAF proto-oncogene serine/threonine-protein kinase sequence variant S257L phosphorylated 1 (human)
|
hRAF1/var:S257L/Phos:1
|
"A RAF proto-oncogene serine/threonine-protein kinase (human) that has a Leu residue at the position equivalent to Ser-257 of the amino acid sequence represented by UniProtKB:P04049-1 and that has been phosphorylated on the residue at the position equivalent to Ser-621. Example: UniProtKB:P04049-1, Ser-257, CHEBI:30006|Ser-621, MOD:00046." [PRO:DNx, Reactome:R-HSA-9656121]
|
|
|
|
|
|
|
| | | | | | |
| | | |
organism-modification
|
|
PR:000062783 |
RAF proto-oncogene serine/threonine-protein kinase sequence variant P261S phosphorylated 2 (human)
|
hRAF1/var:P261S/Phos:2
|
"A RAF proto-oncogene serine/threonine-protein kinase (human) that has a Ser residue at the position equivalent to Pro-261 of the amino acid sequence represented by UniProtKB:P04049-1 and that has been phosphorylated on the residues at the positions equivalent to Ser-338, Tyr-341, Thr-491, Ser-494, and Ser-621. Example: UniProtKB:P04049-1, Pro-261, CHEBI:29999|Ser-338/Ser-494/Ser-621, MOD:00046|Tyr-341, MOD:00048|Thr-491, MOD:00047." [PRO:DNx, Reactome:R-HSA-9656050]
|
|
|
|
|
|
|
| | | | | | |
| | | |
organism-modification
|
|
PR:000062809 |
RAF proto-oncogene serine/threonine-protein kinase sequence variant T491R phosphorylated 1 (human)
|
hRAF1/var:T491R/Phos:1
|
"A RAF proto-oncogene serine/threonine-protein kinase (human) that has an Arg residue at the position equivalent to Thr-491 of the amino acid sequence represented by UniProtKB:P04049-1 and that has been phosphorylated on the residues at the positions equivalent to Ser-338, Tyr-341, Ser-494, and Ser-621. Example: UniProtKB:P04049-1, Ser-338/Ser-494/Ser-621, MOD:00046|Tyr-341, MOD:00048|Thr-491, CHEBI:29952." [PRO:DNx, Reactome:R-HSA-9656017]
|
|
|
|
|
|
|
| | | | | | |
| | | |
organism-modification
|
|
PR:000062928 |
RAF proto-oncogene serine/threonine-protein kinase sequence variant T260I phosphorylated 2 (human)
|
hRAF1/var:T260I/Phos:2
|
"A RAF proto-oncogene serine/threonine-protein kinase (human) that has an Ile residue at the position equivalent to Thr-260 of the amino acid sequence represented by UniProtKB:P04049-1 and that has been phosphorylated on the residues at the positions equivalent to Ser-338, Tyr-341, Thr-491, Ser-494, and Ser-621. Example: UniProtKB:P04049-1, Thr-260, CHEBI:30009|Ser-338/Ser-494/Ser-621, MOD:00046|Tyr-341, MOD:00048|Thr-491, MOD:00047." [PRO:DNx, Reactome:R-HSA-9656074]
|
|
|
|
|
|
|
| | | | | | |
| | | |
organism-modification
|
|
PR:000063034 |
RAF proto-oncogene serine/threonine-protein kinase sequence variant V263A phosphorylated 2 (human)
|
hRAF1/var:V263A/Phos:2
|
"A RAF proto-oncogene serine/threonine-protein kinase (human) that has an Ala residue at the position equivalent to Val-263 of the amino acid sequence represented by UniProtKB:P04049-1 and that has been phosphorylated on the residue at the position equivalent to Ser-621. Example: UniProtKB:P04049-1, Val-263, CHEBI:46217|Ser-621, MOD:00046." [PRO:DNx, Reactome:R-HSA-9656148]
|
|
|
|
|
|
|
| | | | | | |
| | | |
organism-modification
|
|
PR:000063172 |
RAF proto-oncogene serine/threonine-protein kinase sequence variant T491R phosphorylated 2 (human)
|
hRAF1/var:T491R/Phos:2
|
"A RAF proto-oncogene serine/threonine-protein kinase (human) that has an Arg residue at the position equivalent to Thr-491 of the amino acid sequence represented by UniProtKB:P04049-1 and that has been phosphorylated on the residue at the position equivalent to Ser-621. Example: UniProtKB:P04049-1, Thr-491, CHEBI:29952|Ser-621, MOD:00046." [PRO:DNx, Reactome:R-HSA-9656145]
|
|
|
|
|
|
|
| | | | | | |
| | | |
organism-modification
|
|
PR:000063187 |
RAF proto-oncogene serine/threonine-protein kinase sequence variant S257L phosphorylated 2 (human)
|
hRAF1/var:S257L/Phos:2
|
"A RAF proto-oncogene serine/threonine-protein kinase (human) that has a Leu residue at the position equivalent to Ser-257 of the amino acid sequence represented by UniProtKB:P04049-1 and that has been phosphorylated on the residues at the positions equivalent to Ser-338, Tyr-341, Thr-491, Ser-494, and Ser-621. Example: UniProtKB:P04049-1, Ser-257, CHEBI:30006|Ser-338/Ser-494/Ser-621, MOD:00046|Tyr-341, MOD:00048|Thr-491, MOD:00047." [PRO:DNx, Reactome:R-HSA-9656058]
|
|
|
|
|
|
|
| | | | | | |
| | | |
organism-modification
|
|
PR:000063405 |
RAF proto-oncogene serine/threonine-protein kinase sequence variant D486G phosphorylated 2 (human)
|
hRAF1/var:D486G/Phos:2
|
"A RAF proto-oncogene serine/threonine-protein kinase (human) that has a Gly residue at the position equivalent to Asp-486 of the amino acid sequence represented by UniProtKB:P04049-1 and that has been phosphorylated on the residues at the positions equivalent to Ser-338, Tyr-341, Thr-491, Ser-494, and Ser-621. Example: UniProtKB:P04049-1, Ser-338/Ser-494/Ser-621, MOD:00046|Tyr-341, MOD:00048|Asp-486, CHEBI:29947|Thr-491, MOD:00047." [PRO:DNx, Reactome:R-HSA-9656023]
|
|
|
|
|
|
|
| | | | | | |
| | | |
organism-modification
|
|
PR:000063408 |
RAF proto-oncogene serine/threonine-protein kinase sequence variant G361A phosphorylated 1 (human)
|
hRAF1/var:G361A/Phos:1
|
"A RAF proto-oncogene serine/threonine-protein kinase (human) that has an Ala residue at the position equivalent to Gly-361 of the amino acid sequence represented by UniProtKB:P04049-1 and that has been phosphorylated on the residue at the position equivalent to Ser-621. Example: UniProtKB:P04049-1, Gly-361, CHEBI:46217|Ser-621, MOD:00046." [PRO:DNx, Reactome:R-HSA-9656092]
|
|
|
|
|
|
|
| | | | | | |
| | | |
organism-modification
|
|
PR:000063432 |
RAF proto-oncogene serine/threonine-protein kinase sequence variant R256S phosphorylated 2 (human)
|
hRAF1/var:R256S/Phos:2
|
"A RAF proto-oncogene serine/threonine-protein kinase (human) that has a Ser residue at the position equivalent to Arg-256 of the amino acid sequence represented by UniProtKB:P04049-1 and that has been phosphorylated on the residue at the position equivalent to Ser-621. Example: UniProtKB:P04049-1, Arg-256, CHEBI:29999|Ser-621, MOD:00046." [PRO:DNx, Reactome:R-HSA-9656119]
|
|
|
|
|
|
|
| | | | | | |
| | | |
organism-modification
|
|
PR:000063451 |
RAF proto-oncogene serine/threonine-protein kinase sequence variant T491I phosphorylated 1 (human)
|
hRAF1/var:T491I/Phos:1
|
"A RAF proto-oncogene serine/threonine-protein kinase (human) that has an Ile residue at the position equivalent to Thr-491 of the amino acid sequence represented by UniProtKB:P04049-1 and that has been phosphorylated on the residues at the positions equivalent to Ser-338, Tyr-341, Ser-494, and Ser-621. Example: UniProtKB:P04049-1, Ser-338/Ser-494/Ser-621, MOD:00046|Tyr-341, MOD:00048|Thr-491, CHEBI:30009." [PRO:DNx, Reactome:R-HSA-9656019]
|
|
|
|
|
|
|
| | | | | | |
| | | |
organism-modification
|
|
PR:000063537 |
RAF proto-oncogene serine/threonine-protein kinase sequence variant T260R phosphorylated 1 (human)
|
hRAF1/var:T260R/Phos:1
|
"A RAF proto-oncogene serine/threonine-protein kinase (human) that has an Arg residue at the position equivalent to Thr-260 of the amino acid sequence represented by UniProtKB:P04049-1 and that has been phosphorylated on the residue at the position equivalent to Ser-621. Example: UniProtKB:P04049-1, Thr-260, CHEBI:29952|Ser-621, MOD:00046." [PRO:DNx, Reactome:R-HSA-9656139]
|
|
|
|
|
|
|
| | | | | | |
| | | |
organism-modification
|
|
PR:000063579 |
RAF proto-oncogene serine/threonine-protein kinase sequence variant P261T phosphorylated 2 (human)
|
hRAF1/var:P261T/Phos:2
|
"A RAF proto-oncogene serine/threonine-protein kinase (human) that has a Thr residue at the position equivalent to Pro-261 of the amino acid sequence represented by UniProtKB:P04049-1 and that has been phosphorylated on the residues at the positions equivalent to Ser-338, Tyr-341, Thr-491, Ser-494, and Ser-621. Example: UniProtKB:P04049-1, Pro-261, CHEBI:30013|Ser-338/Ser-494/Ser-621, MOD:00046|Tyr-341, MOD:00048|Thr-491, MOD:00047." [PRO:DNx, Reactome:R-HSA-9656053]
|
|
|
|
|
|
|
| | | | | | |
| | | |
organism-modification
|
|
PR:000063663 |
RAF proto-oncogene serine/threonine-protein kinase sequence variant S259T phosphorylated 2 (human)
|
hRAF1/var:S259T/Phos:2
|
"A RAF proto-oncogene serine/threonine-protein kinase (human) that has a Thr residue at the position equivalent to Ser-259 of the amino acid sequence represented by UniProtKB:P04049-1 and that has been phosphorylated on the residue at the position equivalent to Ser-621. Example: UniProtKB:P04049-1, Ser-259, CHEBI:30013|Ser-621, MOD:00046." [PRO:DNx, Reactome:R-HSA-9656130]
|
|
|
|
|
|
|
| | | | | | |
| | | |
organism-modification
|
|
PR:000063974 |
RAF proto-oncogene serine/threonine-protein kinase sequence variant T491I phosphorylated 2 (human)
|
hRAF1/var:T491I/Phos:2
|
"A RAF proto-oncogene serine/threonine-protein kinase (human) that has an Ile residue at the position equivalent to Thr-491 of the amino acid sequence represented by UniProtKB:P04049-1 and that has been phosphorylated on the residue at the position equivalent to Ser-621. Example: UniProtKB:P04049-1, Thr-491, CHEBI:30009|Ser-621, MOD:00046." [PRO:DNx, Reactome:R-HSA-9656143]
|
|
|
|
|
|
|
| | | | | | |
| | | |
organism-modification
|
|
PR:000064065 |
RAF proto-oncogene serine/threonine-protein kinase sequence variant T260R phosphorylated 2 (human)
|
hRAF1/var:T260R/Phos:2
|
"A RAF proto-oncogene serine/threonine-protein kinase (human) that has an Arg residue at the position equivalent to Thr-260 of the amino acid sequence represented by UniProtKB:P04049-1 and that has been phosphorylated on the residues at the positions equivalent to Ser-338, Tyr-341, Thr-491, Ser-494, and Ser-621. Example: UniProtKB:P04049-1, Thr-260, CHEBI:29952|Ser-338/Ser-494/Ser-621, MOD:00046|Tyr-341, MOD:00048|Thr-491, MOD:00047." [PRO:DNx, Reactome:R-HSA-9656077]
|
|
|
|
|
|
|
| | | | | | |
| | | |
organism-modification
|
|
PR:000064095 |
RAF proto-oncogene serine/threonine-protein kinase sequence variant P261N phosphorylated 2 (human)
|
hRAF1/var:P261N/Phos:2
|
"A RAF proto-oncogene serine/threonine-protein kinase (human) that has an Asn residue at the position equivalent to Pro-261 of the amino acid sequence represented by UniProtKB:P04049-1 and that has been phosphorylated on the residues at the positions equivalent to Ser-338, Tyr-341, Thr-491, Ser-494, and Ser-621. Example: UniProtKB:P04049-1, Pro-261, CHEBI:50347|Ser-338/Ser-494/Ser-621, MOD:00046|Tyr-341, MOD:00048|Thr-491, MOD:00047." [PRO:DNx, Reactome:R-HSA-9656047]
|
|
|
|
|
|
|
| | | | | | |
| | | |
organism-modification
|
|
PR:000064135 |
RAF proto-oncogene serine/threonine-protein kinase phosphotyrosine form (human)
|
hRAF1/PhosTyr+
|
"A RAF proto-oncogene serine/threonine-protein kinase (human) that includes at least one phosphorylated tyrosine. UniProtKB:P04049, MOD:00048." [PRO:DNx, Reactome:R-HSA-9732747]
|
|
|
|
|
|
|
| | | | | | |
| | | |
organism-modification
|
|
PR:000064182 |
RAF proto-oncogene serine/threonine-protein kinase sequence variant S259F phosphorylated 1 (human)
|
hRAF1/var:S259F/Phos:1
|
"A RAF proto-oncogene serine/threonine-protein kinase (human) that has a Phe residue at the position equivalent to Ser-259 of the amino acid sequence represented by UniProtKB:P04049-1 and that has been phosphorylated on the residue at the position equivalent to Ser-621. Example: UniProtKB:P04049-1, Ser-259, CHEBI:29997|Ser-621, MOD:00046." [PRO:DNx, Reactome:R-HSA-9656124]
|
|
|
|
|
|
|
| | | | | | |
| | | |
organism-modification
|
|
PR:000064238 |
RAF proto-oncogene serine/threonine-protein kinase sequence variant G361A phosphorylated 2 (human)
|
hRAF1/var:G361A/Phos:2
|
"A RAF proto-oncogene serine/threonine-protein kinase (human) that has an Ala residue at the position equivalent to Gly-361 of the amino acid sequence represented by UniProtKB:P04049-1 and that has been phosphorylated on the residues at the positions equivalent to Ser-338, Tyr-341, Thr-491, Ser-494, and Ser-621. Example: UniProtKB:P04049-1, Ser-338/Ser-494/Ser-621, MOD:00046|Tyr-341, MOD:00048|Gly-361, CHEBI:46217|Thr-491, MOD:00047." [PRO:DNx, Reactome:R-HSA-9656029]
|
|
|
|
|
|
|
| | | | | | |
| | | |
organism-modification
|
|
PR:000064242 |
RAF proto-oncogene serine/threonine-protein kinase sequence variant N262L phosphorylated 2 (human)
|
hRAF1/var:N262L/Phos:2
|
"A RAF proto-oncogene serine/threonine-protein kinase (human) that has a Leu residue at the position equivalent to Asn-262 of the amino acid sequence represented by UniProtKB:P04049-1 and that has been phosphorylated on the residues at the positions equivalent to Ser-338, Tyr-341, Thr-491, Ser-494, and Ser-621. Example: UniProtKB:P04049-1, Asn-262, CHEBI:30006|Ser-338/Ser-494/Ser-621, MOD:00046|Tyr-341, MOD:00048|Thr-491, MOD:00047." [PRO:DNx, Reactome:R-HSA-9656037]
|
|
|
|
|
|
|
| | | | | | |
| | | |
organism-modification
|
|
PR:000064564 |
RAF proto-oncogene serine/threonine-protein kinase sequence variant S259F phosphorylated 2 (human)
|
hRAF1/var:S259F/Phos:2
|
"A RAF proto-oncogene serine/threonine-protein kinase (human) that has a Phe residue at the position equivalent to Ser-259 of the amino acid sequence represented by UniProtKB:P04049-1 and that has been phosphorylated on the residues at the positions equivalent to Ser-338, Tyr-341, Thr-491, Ser-494, and Ser-621. Example: UniProtKB:P04049-1, Ser-259, CHEBI:29997|Ser-338/Ser-494/Ser-621, MOD:00046|Tyr-341, MOD:00048|Thr-491, MOD:00047." [PRO:DNx, Reactome:R-HSA-9656062]
|
|
|
|
|
|
|
| | | | | | |
| | | |
organism-modification
|
|
PR:000065842 |
RAF proto-oncogene serine/threonine-protein kinase phosphorylated 2 (human)
|
hRAF1/Phos:2
|
"A RAF proto-oncogene serine/threonine-protein kinase (human) that has been phosphorylated on the residue at the position equivalent to Ser-233 of the amino acid sequence represented by UniProtKB:P04049-1. Example: UniProtKB:P04049-1, Ser-233, MOD:00046." [IEDB_epitope:912120, PRO:DNx]
|
|
|
|
|
|
|
| | | | | | |
| | | |
organism-modification
|
|
PR:000070181 |
RAF proto-oncogene serine/threonine-protein kinase deaminated 1 (human)
|
hRAF1/Deam:1
|
"A RAF proto-oncogene serine/threonine-protein kinase (human) that has been deaminated on the residue at the position equivalent to Asn-13 of the amino acid sequence represented by UniProtKB:P04049-1. Example: UniProtKB:P04049-1, Asn-13, MOD:00684." [IEDB_epitope:860660, PRO:DNx]
|
|
|
|
|
|
|
| | | | | | |
| | | |
organism-modification
|
|
PR:000078506 |
RAF proto-oncogene serine/threonine-protein kinase cysteinylated 1 (human)
|
hRAF1/Cyst:1
|
"A RAF proto-oncogene serine/threonine-protein kinase (human) that has been cysteinylated on the residue at the position equivalent to Cys-27 of the amino acid sequence represented by UniProtKB:P04049-1. Example: UniProtKB:P04049-1, Cys-27, MOD:00765." [IEDB_epitope:1591920, PRO:DNx]
|
|
|
|
|
|
|
| | | | |
| | | | | |
organism-gene
|
|
PR:P05625 |
RAF proto-oncogene serine/threonine-protein kinase (chicken)
|
chick-RAF1
|
"A RAF proto-oncogene serine/threonine-protein kinase that is encoded in the genome of chicken." [OMA:P05625, PRO:DNx]
|
|
|
|
|
|
|
| | | | | | |
| | | |
organism-sequence
|
|
PR:P05625-1 |
RAF proto-oncogene serine/threonine-protein kinase isoform 1 (chicken)
|
chick-RAF1/iso:1
|
"A RAF proto-oncogene serine/threonine-protein kinase (chicken) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P05625-1." [PRO:DNx, UniProtKB:P05625]
|
|
|
|
|
|
|
| | | | | | |
| | | |
organism-sequence
|
|
PR:P05625-2 |
RAF proto-oncogene serine/threonine-protein kinase isoform 2 (chicken)
|
chick-RAF1/iso:2
|
"A RAF proto-oncogene serine/threonine-protein kinase (chicken) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P05625-2." [PRO:DNx, UniProtKB:P05625]
|
|
|
|
|
|
|
| | | | |
| | | | | |
organism-gene
|
|
PR:P06784 |
serine/threonine-protein kinase STE7 (yeast)
|
ySTE7
|
"A RAF proto-oncogene serine/threonine-protein kinase that is encoded in the genome of yeast." [OMA:P06784, PRO:DNx]
|
|
|
|
|
|
|
| | | | |
| | | | | |
organism-gene
|
|
PR:P11345 |
RAF proto-oncogene serine/threonine-protein kinase (rat)
|
rRAF1
|
"A RAF proto-oncogene serine/threonine-protein kinase that is encoded in the genome of rat." [OMA:P11345, PRO:DNx]
|
|
|
|
|
|
|
| | | | |
| | | | | |
organism-gene
|
|
PR:Q54TH6 |
probable serine/threonine-protein kinase DDB_G0281745 (Dictyostelium discoideum)
|
Dicty-RAF1
|
"A RAF proto-oncogene serine/threonine-protein kinase that is encoded in the genome of Dictyostelium discoideum." [PRO:CNA]
|
|
|
|
|
|
|
| | | | |
| | | | | |
organism-gene
|
|
PR:Q99N57 |
RAF proto-oncogene serine/threonine-protein kinase (mouse)
|
mRAF1
|
"A RAF proto-oncogene serine/threonine-protein kinase that is encoded in the genome of mouse." [OMA:Q99N57, PRO:DNx]
|
|
|
|
|
|
|
| | | | | | |
| | | |
organism-sequence
|
|
PR:Q99N57-1 |
RAF proto-oncogene serine/threonine-protein kinase isoform 1 (mouse)
|
mRAF1/iso:1
|
"A RAF proto-oncogene serine/threonine-protein kinase isoform 1 that is encoded in the genome of mouse." [PRO:CNA]
|
|
|
|
|
|
|
| | | | | | |
| | | |
organism-sequence
|
|
PR:Q99N57-2 |
RAF proto-oncogene serine/threonine-protein kinase isoform 2 (mouse)
|
mRAF1/iso:2
|
"A RAF proto-oncogene serine/threonine-protein kinase isoform 2 that is encoded in the genome of mouse." [PRO:CNA]
|
|
|
|
|
|
|
| | | | | | |
| | | |
organism-modification
|
|
PR:000046209 |
RAF proto-oncogene serine/threonine-protein kinase phosphorylated 1 (mouse)
|
mRAF1/Phos:1
|
"A RAF proto-oncogene serine/threonine-protein kinase (mouse) that has been phosphorylated on the residue at the position equivalent to Ser-621 of the amino acid sequence represented by UniProtKB:Q99N57-1. Example: UniProtKB:Q99N57-1, Ser-621, MOD:00046." [iPTMnet:Q99N57, PMID:18922468]
|
|
|
|
|
|
|
| | | | |
| | | | | |
sequence
|
|
PR:000003245 |
RAF proto-oncogene serine/threonine-protein kinase isoform 1
|
RAF1/iso:1
|
"A RAF proto-oncogene serine/threonine-protein kinase that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P04049-1 or a 1:1 ortholog thereof." [PRO:CNA]
|
|
|
|
|
|
|
| | | | | | |
| | | |
organism-sequence
|
|
PR:P04049-1 |
RAF proto-oncogene serine/threonine-protein kinase isoform 1 (human)
|
hRAF1/iso:1
|
"A RAF proto-oncogene serine/threonine-protein kinase isoform 1 that is encoded in the genome of human." [PRO:CNA]
|
|
|
|
|
|
|
| | | | | | | | |
| |
organism-modification
|
|
PR:000026210 |
RAF proto-oncogene serine/threonine-protein kinase isoform 1 phosphorylated 3 (human)
|
hRAF1/iso:1/Phos:3
|
"A RAF proto-oncogene serine/threonine-protein kinase isoform 1 phosphorylated 3 in human. UniProtKB:P04049-1, Ser-259/Ser-621, MOD:00046." [PMID:14688280, PRO:CNA]
|
|
|
|
|
|
|
| | | | | | | | |
| |
organism-modification
|
|
PR:000036643 |
RAF proto-oncogene serine/threonine-protein kinase isoform 1 phosphorylated 2 (human)
|
hRAF1/iso:1/Phos:2
|
"A RAF proto-oncogene serine/threonine-protein kinase isoform 1 phosphorylated 2 in human. UniProtKB:P04049-1, Ser-338/Ser-339, MOD:00046." [PMID:15849194, PRO:JAN]
|
Yes |
|
|
|
|
|
| | | | | | |
| | | |
organism-sequence
|
|
PR:Q99N57-1 |
RAF proto-oncogene serine/threonine-protein kinase isoform 1 (mouse)
|
mRAF1/iso:1
|
"A RAF proto-oncogene serine/threonine-protein kinase isoform 1 that is encoded in the genome of mouse." [PRO:CNA]
|
|
|
|
|
|
|
| | | | | | |
| | | |
modification
|
|
PR:000003247 |
RAF proto-oncogene serine/threonine-protein kinase isoform 1 phosphorylated form
|
RAF1/iso:1/PhosRes+
|
"A RAF proto-oncogene serine/threonine-protein kinase isoform 1 that includes at least one phosphorylated residue." [PRO:CNA]
|
|
|
|
|
|
|
| | | | | | | | |
| |
modification
|
|
PR:000003249 |
RAF proto-oncogene serine/threonine-protein kinase isoform 1 phosphorylated 1
|
RAF1/iso:1/Phos:1
|
"A RAF proto-oncogene serine/threonine-protein kinase isoform 1 phosphorylated form in which the phosphorylation occurs at two consecutive Tyr residues by active Src kinases. Example: UniProtKB:P04049-1, Tyr-340/Tyr-341, MOD:00048." [PMID:7692235]
|
|
|
|
|
|
|
| | | | | | | | |
| |
modification
|
|
PR:000003250 |
RAF proto-oncogene serine/threonine-protein kinase isoform 1 phosphorylated 2
|
RAF1/iso:1/Phos:2
|
"A RAF proto-oncogene serine/threonine-protein kinase isoform 1 phosphorylated form in which the phosphorylation occurs at two consecutive Ser residues by PAK1. Example: UniProtKB:P04049-1, Ser-338/Ser-339, MOD:00046." [PMID:15849194, PRO:JAN]
|
|
|
|
|
|
|
| | | | | | | | | | |
organism-modification
|
|
PR:000036643 |
RAF proto-oncogene serine/threonine-protein kinase isoform 1 phosphorylated 2 (human)
|
hRAF1/iso:1/Phos:2
|
"A RAF proto-oncogene serine/threonine-protein kinase isoform 1 phosphorylated 2 in human. UniProtKB:P04049-1, Ser-338/Ser-339, MOD:00046." [PMID:15849194, PRO:JAN]
|
Yes |
|
|
|
|
|
| | | | | | | | |
| |
modification
|
|
PR:000026174 |
RAF proto-oncogene serine/threonine-protein kinase isoform 1 phosphorylated 3
|
RAF1/iso:1/Phos:3
|
"A RAF proto-oncogene serine/threonine-protein kinase isoform 1 that has been phosphorylated on the two 14-3-3 binding sites. Example: UniProtKB:P04049-1, Ser-259/Ser-621, MOD:00046." [PMID:14688280, PRO:CNA]
|
|
|
|
|
|
|
| | | | | | | | | | |
organism-modification
|
|
PR:000026210 |
RAF proto-oncogene serine/threonine-protein kinase isoform 1 phosphorylated 3 (human)
|
hRAF1/iso:1/Phos:3
|
"A RAF proto-oncogene serine/threonine-protein kinase isoform 1 phosphorylated 3 in human. UniProtKB:P04049-1, Ser-259/Ser-621, MOD:00046." [PMID:14688280, PRO:CNA]
|
|
|
|
|
|
|
| | | | |
| | | | | |
sequence
|
|
PR:000003248 |
RAF proto-oncogene serine/threonine-protein kinase isoform 2
|
RAF1/iso:2
|
"A RAF proto-oncogene serine/threonine-protein kinase that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P04049-2 or a 1:1 ortholog thereof." [PRO:CNA]
|
|
|
|
|
|
|
| | | | | | |
| | | |
organism-sequence
|
|
PR:P04049-2 |
RAF proto-oncogene serine/threonine-protein kinase isoform 2 (human)
|
hRAF1/iso:2
|
"A RAF proto-oncogene serine/threonine-protein kinase isoform 2 that is encoded in the genome of human." [PRO:CNA]
|
|
|
|
|
|
|
| | | | | | |
| | | |
organism-sequence
|
|
PR:Q99N57-2 |
RAF proto-oncogene serine/threonine-protein kinase isoform 2 (mouse)
|
mRAF1/iso:2
|
"A RAF proto-oncogene serine/threonine-protein kinase isoform 2 that is encoded in the genome of mouse." [PRO:CNA]
|
|
|
|
|
