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Protein Ontology report - RAF proto-oncogene serine/threonine-protein kinase isoform 1 phosphorylated 2
PR:000003250 - http://purl.obolibrary.org/obo/PR_000003250
 
  Protein Forms  Annotations      
Ontology Information Show OBO stanza
  PRO ID
PR:000003250   
  PRO nameRAF proto-oncogene serine/threonine-protein kinase isoform 1 phosphorylated 2 
  Synonyms
PRO-Short-label: EXACT:RAF1/iso:1/Phos:2
  Definition"A RAF proto-oncogene serine/threonine-protein kinase isoform 1 phosphorylated form in which the phosphorylation occurs at two consecutive Ser residues by PAK1. Example: UniProtKB:P04049-1, Ser-338/Ser-339, MOD:00046." [PMID:15849194, PRO:JAN] 
  PRO Categorymodification 
  ParentPR:000003247 RAF proto-oncogene serine/threonine-protein kinase isoform 1 phosphorylated form
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Modification1                                                  Organism-Modification 1                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Protein Forms  Switch to Extended View   

Category  
PRO Form Name
Short Name
Ann. Has Annotation?

Comp. In Complex?
modification


PR:000003250 RAF proto-oncogene serine/threonine-protein kinase isoform 1 phosphorylated 2
RAF1/iso:1/Phos:2

organism-modification


PR:000036643 RAF proto-oncogene serine/threonine-protein kinase isoform 1 phosphorylated 2 (human)
hRAF1/iso:1/Phos:2
Yes
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Functional Annotation (PRO-centric view) Switch to GO Centric View   
PRO Term GO Annotation Evidence
PR:000036643 hRAF1/iso:1/Phos:2
UniProtKB:P04049-1, Ser-338/Ser-339, MOD:00046		 acts_upstream_of_or_withinGO:0043066 negative regulation of apoptotic process PMID:15849194
enablesGO:0004674 protein serine/threonine kinase activity PMID:15849194
GO:0005515 protein binding PMID:15849194
located_inGO:0005741 mitochondrial outer membrane PMID:15849194