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Protein Ontology report - dual specificity mitogen-activated protein kinase kinase 4
PR:000003283 - http://purl.obolibrary.org/obo/PR_000003283
 
  Protein Forms      
Ontology Information Show OBO stanza
  PRO ID
PR:000003283   
  PRO namedual specificity mitogen-activated protein kinase kinase 4 
  Synonyms
PRO-Short-label: EXACT:MAP2K4
Gene-based: RELATED:JNKK1 | MEK4 | MKK4 | PRKMK4 | SEK1 | SERK1 | SKK1
Other: EXACT:c-Jun N-terminal kinase kinase 1 | JNK kinase 1 | JNK-activating kinase 1 | JNKK | JNKK 1 | MAP kinase kinase 4 | MAPK/ERK kinase 4 | MAPKK 4 | MEK 4 | SAPK/ERK kinase 1
  Definition"A protein that is a translation product of the human MAP2K4 gene or a 1:1 ortholog thereof." [TLR:AMM] 
  CommentRequested by=TLR. 
  PRO Categorygene 
  ParentPR:000000001 protein
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Gene1                                                  Organism-Gene 3                                        
         Sequence0                                                  Organism-Sequence 2                                        
         Modification3                                                  Organism-Modification 1                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Related Cross References

  Db identifiers
IUPHARobj:2065
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Protein Forms Switch to Compact View   

Category  

PRO ID

Name

Short Name

Definition

Ann. Has Annotation?

Comp. In Complex?
gene



PR:000003283

dual specificity mitogen-activated protein kinase kinase 4

MAP2K4


"A protein that is a translation product of the human MAP2K4 gene or a 1:1 ortholog thereof." [TLR:AMM]


organism-gene



PR:P45985

dual specificity mitogen-activated protein kinase kinase 4 (human)

hMAP2K4


"A dual specificity mitogen-activated protein kinase kinase 4 that is encoded in the genome of human." [TLR:AMM, UniProtKB:P45985]


organism-sequence



PR:P45985-1

dual specificity mitogen-activated protein kinase kinase 4 isoform h1 (human)

hMAP2K4/iso:h1


"A dual specificity mitogen-activated protein kinase kinase 4 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P45985-1." [PRO:DNx, UniProtKB:P45985]


organism-sequence



PR:P45985-2

dual specificity mitogen-activated protein kinase kinase 4 isoform h2 (human)

hMAP2K4/iso:h2


"A dual specificity mitogen-activated protein kinase kinase 4 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P45985-2." [PRO:DNx, UniProtKB:P45985]


organism-modification



PR:000048298

dual specificity mitogen-activated protein kinase kinase 4 phosphorylated 1 (human)

hMAP2K4/Phos:1


"A dual specificity mitogen-activated protein kinase kinase 4 (human) that has been phosphorylated on the residue at the position equivalent to Ser-257, and phosphothreonine at position 261 of the amino acid sequence represented by UniProtKB:P45985. UniProtKB:P45985, Ser-257, MOD:00046|Thr-261, MOD:00047." [PRO:DNx, Reactome:R-HSA-168170]


organism-gene



PR:P47809

dual specificity mitogen-activated protein kinase kinase 4 (mouse)

mMAP2K4


"A dual specificity mitogen-activated protein kinase kinase 4 that is encoded in the genome of mouse." [OMA:P47809, PRO:DNx]


organism-gene



PR:Q20347

MAP kinase kinase mkk-4 (worm)

MAP2K4 (worm)


"A dual specificity mitogen-activated protein kinase kinase 4 that is encoded in the genome of worm." [OMA:Q20347, PRO:DNx]


modification



PR:000018804

dual specificity mitogen-activated protein kinase kinase 4, initiator methionine removed form

MAP2K4/InitMet-


"A dual specificity mitogen-activated protein kinase kinase 4 that has had the initiator methionine removed." [PRO:DNx]


modification



PR:000021995

dual specificity mitogen-activated protein kinase kinase 4 phosphorylated form

MAP2K4/PhosRes+


"A dual specificity mitogen-activated protein kinase kinase 4 that includes at least one phosphorylated residue." [TLR:AMM]


modification



PR:000021996

dual specificity mitogen-activated protein kinase kinase 4 phosphorylated 1

MAP2K4/Phos:1


"A dual specificity mitogen-activated protein kinase kinase 4 phosphorylated form in which the phosphorylation occurs on Ser/Thr residues within the activation loop by MAP kinase kinase kinases." [PMID:10785355, TLR:AMM]


organism-modification



PR:000048298

dual specificity mitogen-activated protein kinase kinase 4 phosphorylated 1 (human)

hMAP2K4/Phos:1


"A dual specificity mitogen-activated protein kinase kinase 4 (human) that has been phosphorylated on the residue at the position equivalent to Ser-257, and phosphothreonine at position 261 of the amino acid sequence represented by UniProtKB:P45985. UniProtKB:P45985, Ser-257, MOD:00046|Thr-261, MOD:00047." [PRO:DNx, Reactome:R-HSA-168170]