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Protein Ontology report - phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase 1
PR:000003302 - http://purl.obolibrary.org/obo/PR_000003302
 
  Protein Forms  Annotations      
Ontology Information Show OBO stanza
  PRO ID
PR:000003302   
  PRO namephosphatidylinositol-3,4,5-trisphosphate 5-phosphatase 1 
  Synonyms
PRO-Short-label: EXACT:INPP5D
Gene-based: RELATED:7a33 | SHIP | SHIP1
Other: EXACT:hp51CN | inositol polyphosphate-5-phosphatase D | inositol polyphosphate-5-phosphatase of 145 kDa | p150Ship | SH2 domain-containing inositol 5'-phosphatase 1 | SH2 domain-containing inositol phosphatase 1 | SH2 domain-containing inositol-5'-phosphatase 1 | SHIP-1 | SIP-145
  Definition"A protein that is a translation product of the human INPP5D gene or a 1:1 ortholog thereof." [PRO:HJD] 
  PRO Categorygene 
  ParentPR:000000001 protein
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Gene1                                                  Organism-Gene 3                                        
         Sequence6                                                  Organism-Sequence 9                                        
         Modification4                                                  Organism-Modification 10                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Related Cross References

  Db identifiers
IUPHARobj:1455
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Protein Forms  Switch to Extended View   

Category  
PRO Form Name
Short Name
Ann. Has Annotation?

Comp. In Complex?
gene


PR:000003302 phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase 1
INPP5D

organism-gene


PR:P97573 phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1 (rat)
rINPP5D

organism-gene


PR:Q92835 phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1 (human)
hINPP5D

organism-sequence


PR:Q92835-1 phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1 isoform h1 (human)
hINPP5D/iso:h1

organism-sequence


PR:Q92835-2 phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1 isoform h2 (human)
hINPP5D/iso:h2

organism-sequence


PR:Q92835-3 phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1 isoform h3 (human)
hINPP5D/iso:h3

organism-modification


PR:000063670 phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1 phosphotyrosine form (human)
hINPP5D/PhosTyr+

organism-modification


PR:000065352 phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1 citrullinated 1 (human)
hINPP5D/Cit:1

organism-modification


PR:000068185 phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1 methylated 1 (human)
hINPP5D/Me:1

organism-modification


PR:000068569 phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1 methylated 2 (human)
hINPP5D/Me:2

organism-modification


PR:000069783 phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1 deaminated 1 (human)
hINPP5D/Deam:1

organism-modification


PR:000071487 phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1 methylated 3 (human)
hINPP5D/Me:3

organism-modification


PR:000071598 phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1 cysteinylated 1 (human)
hINPP5D/Cyst:1

organism-modification


PR:000075843 phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1 methylated 4 (human)
hINPP5D/Me:4

organism-modification


PR:000079399 phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1 methylated 5 (human)
hINPP5D/Me:5

organism-gene


PR:Q9ES52 phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1 (mouse)
mINPP5D

organism-sequence


PR:Q9ES52-1 phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1 isoform 1 (mouse)
mINPP5D/iso:1

organism-sequence


PR:Q9ES52-2 phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1 isoform 2 (mouse)
mINPP5D/iso:2
Yes
organism-modification


PR:000036644 phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase 1 isoform 2 phosphorylated 1 (mouse)
mINPP5D/iso:2/Phos:1
Yes
organism-sequence


PR:Q9ES52-3 phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1 isoform 3 (mouse)
mINPP5D/iso:3

organism-sequence


PR:Q9ES52-4 phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1 isoform 4 (mouse)
mINPP5D/iso:4

organism-sequence


PR:Q9ES52-5 phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1 isoform 5 (mouse)
mINPP5D/iso:5

organism-sequence


PR:Q9ES52-6 phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1 isoform 6 (mouse)
mINPP5D/iso:6

sequence


PR:000003303 phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase 1 isoform 1
INPP5D/iso:1

organism-sequence


PR:Q9ES52-1 phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1 isoform 1 (mouse)
mINPP5D/iso:1

sequence


PR:000003305 phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase 1 isoform 2
INPP5D/iso:2

organism-sequence


PR:Q9ES52-2 phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1 isoform 2 (mouse)
mINPP5D/iso:2
Yes
organism-modification


PR:000036644 phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase 1 isoform 2 phosphorylated 1 (mouse)
mINPP5D/iso:2/Phos:1
Yes
modification


PR:000003314 phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase 1 isoform 2 phosphorylated form
INPP5D/iso:2/PhosRes+

modification


PR:000003313 phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase 1 isoform 2 phosphorylated 1
INPP5D/iso:2/Phos:1

organism-modification


PR:000036644 phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase 1 isoform 2 phosphorylated 1 (mouse)
mINPP5D/iso:2/Phos:1
Yes
sequence


PR:000003307 phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase 1 isoform 3
INPP5D/iso:3

organism-sequence


PR:Q9ES52-3 phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1 isoform 3 (mouse)
mINPP5D/iso:3

modification


PR:000003318 phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase 1 isoform 3 phosphorylated form
INPP5D/iso:3/PhosRes+

modification


PR:000003319 phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase 1 isoform 3 phosphorylated 1
INPP5D/iso:3/Phos:1

sequence


PR:000003309 phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase 1 isoform 4
INPP5D/iso:4

organism-sequence


PR:Q9ES52-4 phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1 isoform 4 (mouse)
mINPP5D/iso:4

sequence


PR:000003311 phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase 1 isoform 5
INPP5D/iso:5

organism-sequence


PR:Q9ES52-5 phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1 isoform 5 (mouse)
mINPP5D/iso:5

sequence


PR:000003315 phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase 1 isoform 6
INPP5D/iso:6

organism-sequence


PR:Q9ES52-6 phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1 isoform 6 (mouse)
mINPP5D/iso:6

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Functional Annotation (PRO-centric view) Switch to GO Centric View   
PRO Term GO Annotation Evidence
PR:000036644 mINPP5D/iso:2/Phos:1 enablesGO:0005515 protein binding with PR:P98083 mSHC1 PMID:8643691
PR:Q9ES52-2 mINPP5D/iso:2 acts_upstream_of_or_withinGO:0008285 negative regulation of cell population proliferation MGI_ref:85574; PMID:8890215
enablesGO:0004445 inositol-polyphosphate 5-phosphatase activity MGI_ref:85578; PMID:8643691
GO:0017124 SH3 domain binding MGI_ref:85578; PMID:8643691
GO:0034594 phosphatidylinositol trisphosphate phosphatase activity MGI_ref:85574; PMID:8890215
GO:0051425 PTB domain binding MGI_ref:85577; PMID:8654924