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Protein Ontology report - thyroid hormone receptor alpha isoform Alpha-2
PR:000003429 - http://purl.obolibrary.org/obo/PR_000003429
 
  Protein Forms  Annotations      
Ontology Information Show OBO stanza
  PRO ID
PR:000003429   
  PRO namethyroid hormone receptor alpha isoform Alpha-2 
  Synonyms
PRO-Short-label: EXACT:THRA/iso:Alpha-2
Other: EXACT:thyroid hormone receptor isoform 1 | thyroid hormone receptor isoform alpha-2 | TR-alpha isoform 1
  Definition"A thyroid hormone receptor alpha that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P63058-1 or a 1:1 ortholog thereof." [PRO:CNA] 
  PRO Categorysequence 
  ParentPR:000003428 thyroid hormone receptor alpha
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Sequence1                                                  Organism-Sequence 3                                        
         Modification0                                                  Organism-Modification 0                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Protein Forms  Switch to Extended View   

Category  
PRO Form Name
Short Name
Ann. Has Annotation?

Comp. In Complex?
sequence


PR:000003429 thyroid hormone receptor alpha isoform Alpha-2
THRA/iso:Alpha-2

organism-sequence


PR:P10827-1 thyroid hormone receptor alpha isoform Alpha-2 (human)
hTHRA/iso:Alpha-2

organism-sequence


PR:P63058-1 thyroid hormone receptor alpha isoform Alpha-2 (mouse)
mTHRA/iso:Alpha-2
Yes
organism-sequence


PR:P63059-1 thyroid hormone receptor alpha isoform Alpha-2 (rat)
rTHRA/iso:Alpha-2

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Functional Annotation (GO-centric view) Switch to PRO Centric View     

Biological Process GO Term
Protein Forms & Complexes
Evidence
GO:0045892 negative regulation of DNA-templated transcriptionPR:P63058-1 mTHRA/iso:Alpha-2 PMID:11641275; PMID:15062575

Molecular Function GO Term
Protein Forms & Complexes
Evidence
GO:0005515 protein bindingPR:P63058-1 mTHRA/iso:Alpha-2 PMID:15322135
PR:P63058-1 mTHRA/iso:Alpha-2 PMID:15322135
PR:P63058-1 mTHRA/iso:Alpha-2 PMID:15322135
PR:P63058-1 mTHRA/iso:Alpha-2 PMID:15322135