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Protein Ontology report - E3 SUMO-protein ligase PIAS2
PR:000003436 - http://purl.obolibrary.org/obo/PR_000003436
 
  Protein Forms  Annotations      
Ontology Information Show OBO stanza
  PRO ID
PR:000003436   
  PRO nameE3 SUMO-protein ligase PIAS2 
  Synonyms
PRO-Short-label: EXACT:PIAS2
Gene-based: RELATED:PIASX
Other: EXACT:androgen receptor-interacting protein 3 | ARIP3 | miz1 | Msx-interacting zinc finger protein | PIAS-NY protein | protein inhibitor of activated STAT x | protein inhibitor of activated STAT2
RELATED:DAB2-interacting protein | DIP
  Definition"An E3 SUMO-protein ligase PIAS that is a translation product of the human PIAS2 gene or a 1:1 ortholog thereof." [MGI:1096566, PRO:HJD] 
  PRO Categorygene 
  ParentPR:000003444 E3 SUMO-protein ligase PIAS
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Gene1                                                  Organism-Gene 3                                        
         Sequence2                                                  Organism-Sequence 8                                        
         Modification0                                                  Organism-Modification 1                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Protein Forms  Switch to Extended View   

Category  
PRO Form Name
Short Name
Ann. Has Annotation?

Comp. In Complex?
gene


PR:000003436 E3 SUMO-protein ligase PIAS2
PIAS2

organism-gene


PR:O75928 E3 SUMO-protein ligase PIAS2 (human)
hPIAS2

organism-sequence


PR:O75928-1 E3 SUMO-protein ligase PIAS2 isoform hPIAS2-beta (human)
hPIAS2/iso:hPIAS2-beta

organism-sequence


PR:O75928-2 E3 SUMO-protein ligase PIAS2 isoform hPIAS2-alpha (human)
hPIAS2/iso:hPIAS2-alpha

organism-sequence


PR:O75928-3 E3 SUMO-protein ligase PIAS2 isoform h3 (human)
hPIAS2/iso:h3

organism-modification


PR:000076505 E3 SUMO-protein ligase PIAS2 cysteinylated 1 (human)
hPIAS2/Cyst:1

organism-gene


PR:Q6AZ28 E3 SUMO-protein ligase PIAS2 (rat)
rPIAS2

organism-gene


PR:Q8C5D8 E3 SUMO-protein ligase PIAS2 (mouse)
mPIAS2

organism-sequence


PR:Q8C5D8-1 E3 SUMO-protein ligase PIAS2 isoform 1 (mouse)
mPIAS2/iso:1
Yes
organism-sequence


PR:Q8C5D8-2 E3 SUMO-protein ligase PIAS2 isoform 2 (mouse)
mPIAS2/iso:2
Yes
organism-sequence


PR:Q8C5D8-3 E3 SUMO-protein ligase PIAS2 isoform 3 (mouse)
mPIAS2/iso:3

organism-sequence


PR:Q8C5D8-4 E3 SUMO-protein ligase PIAS2 isoform 4 (mouse)
mPIAS2/iso:4

organism-sequence


PR:Q8C5D8-5 E3 SUMO-protein ligase PIAS2 isoform 5 (mouse)
mPIAS2/iso:5

sequence


PR:000003437 E3 SUMO-protein ligase PIAS2 isoform 1
PIAS2/iso:1

organism-sequence


PR:Q8C5D8-1 E3 SUMO-protein ligase PIAS2 isoform 1 (mouse)
mPIAS2/iso:1
Yes
sequence


PR:000003442 E3 SUMO-protein ligase PIAS2 isoform 2
PIAS2/iso:2

organism-sequence


PR:Q8C5D8-2 E3 SUMO-protein ligase PIAS2 isoform 2 (mouse)
mPIAS2/iso:2
Yes
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Functional Annotation (PRO-centric view) Switch to GO Centric View   
PRO Term GO Annotation Evidence
PR:Q8C5D8-1 mPIAS2/iso:1 acts_upstream_of_or_withinGO:0006351 DNA-templated transcription MGI_ref:894957; PMID:9256341
GO:0006357 regulation of transcription by RNA polymerase II MGI_ref:894957; PMID:9256341
GO:0016925 protein sumoylation PMID:15767674
GO:0045667 regulation of osteoblast differentiation MGI_ref:3723333; PMID:17623776
GO:0045893 positive regulation of DNA-templated transcription MGI_ref:3723333; PMID:17623776
enablesGO:0003677 DNA binding MGI_ref:894957; PMID:9256341
GO:0005515 protein binding with PR:P29037 mTBP PMID:16522640
GO:0005515 protein binding PMID:16522640
GO:0019789 SUMO transferase activity PMID:15767674
located_inGO:0005634 nucleus PMID:16522640
GO:0016604 nuclear body MGI_ref:3629292; PMID:16675951
PR:Q8C5D8-2 mPIAS2/iso:2 acts_upstream_of_or_withinGO:0045944 positive regulation of transcription by RNA polymerase II MGI_ref:1929027; PMID:11104669
enablesGO:0005515 protein binding with PR:P98078-3 MGI_ref:1929027; PMID:11104669