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Protein Ontology report - early growth response protein 2

PR:000003469 - http://purl.obolibrary.org/obo/PR_000003469

Protein Forms

Annotations

Ontology Information

Show OBO stanza

PRO ID

PR:000003469

PRO name

early growth response protein 2

Synonyms

PRO-Short-label:	EXACT:	EGR2
Gene-based:	RELATED:	Krox-20 \| KROX20 \| Zfp-25
Other:	EXACT:	AT591 \| E3 SUMO-protein transferase ERG2 \| EGR-2 \| zinc finger protein Krox-20

Definition

"A protein that is a translation product of the human EGR2 gene or a 1:1 ortholog thereof." [PRO:CNA]

Comment

Requested by=CL.

PRO Category

gene

Parent

PR:000000001 protein

Terms by PRO Category

Organism-Independent		Organism-Specific
Category	Number of Terms	Category	Number of Terms
Gene	1	Organism-Gene	4
Sequence	2	Organism-Sequence	6
Modification	0	Organism-Modification	0

Term Hierarchy
Visualization

DAG:

OLS:

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Protein Forms

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Category

PRO Form Name

Short Name

Ann. Has Annotation?

Comp. In Complex?

gene

PR:000003469 early growth response protein 2

EGR2

organism-gene

PR:P08152 E3 SUMO-protein ligase EGR2 (mouse)

mEGR2

Yes

organism-sequence

PR:P08152-1 E3 SUMO-protein ligase EGR2 isoform Long (mouse)

mEGR2/iso:Long

Yes

organism-sequence

PR:P08152-2 E3 SUMO-protein ligase EGR2 isoform Short (mouse)

mEGR2/iso:Short

Yes

organism-gene

PR:P11161 E3 SUMO-protein ligase EGR2 (human)

hEGR2

organism-sequence

PR:P11161-1 E3 SUMO-protein ligase EGR2 isoform Long (human)

hEGR2/iso:Long

organism-sequence

PR:P11161-2 E3 SUMO-protein ligase EGR2 isoform Short (human)

hEGR2/iso:Short

organism-gene

PR:P51774 E3 SUMO-protein ligase EGR2 (rat)

rEGR2

organism-sequence

PR:P51774-1 E3 SUMO-protein ligase EGR2 isoform Long (rat)

rEGR2/iso:Long

organism-sequence

PR:P51774-2 E3 SUMO-protein ligase EGR2 isoform Short (rat)

rEGR2/iso:Short

organism-gene

PR:Q05159 early growth response protein 2b (zebrafish)

z-EGR2

sequence

PR:000003470 early growth response protein 2 isoform Long

EGR2/iso:Long

organism-sequence

PR:P08152-1 E3 SUMO-protein ligase EGR2 isoform Long (mouse)

mEGR2/iso:Long

Yes

organism-sequence

PR:P11161-1 E3 SUMO-protein ligase EGR2 isoform Long (human)

hEGR2/iso:Long

sequence

PR:000022018 early growth response protein 2 isoform Short

EGR2/iso:Short

organism-sequence

PR:P11161-2 E3 SUMO-protein ligase EGR2 isoform Short (human)

hEGR2/iso:Short

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Functional Annotation (PRO-centric view)

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PRO Term	GO Annotation		Evidence
PR:P08152 mEGR2	acts_upstream_of_or_within	GO:0006355 regulation of DNA-templated transcription	PMID:16136673
		GO:0006355 regulation of DNA-templated transcription	PMID:16136673
		GO:0007622 rhythmic behavior	PMID:8893031
		GO:0008045 motor neuron axon guidance	PMID:9806922
		GO:0014037 Schwann cell differentiation	PMID:16136673
		GO:0021569 rhombomere 3 development	PMID:9806922
		GO:0021612 facial nerve structural organization	PMID:9806922
		GO:0021660 rhombomere 3 formation	PMID:7903221
		GO:0021666 rhombomere 5 formation	PMID:7903221
		GO:0030278 regulation of ossification	PMID:8565822
		GO:0042552 myelination	PMID:16136673
		GO:0042552 myelination	PMID:16136673
PR:P08152-1 mEGR2/iso:Long	acts_upstream_of_or_within	GO:0007622 rhythmic behavior	PMID:8893031
	acts_upstream_of_or_within	GO:0045944 positive regulation of transcription by RNA polymerase II	PMID:8093858
	enables	GO:0003677 DNA binding	PMID:8093858; PMID:8895582
	enables	GO:0003700 DNA-binding transcription factor activity	PMID:8093858
	located_in	GO:0005634 nucleus	PMID:15282162
PR:P08152-2 mEGR2/iso:Short	enables	GO:0005515 protein binding with PR:Q8C5D8-1	MGI_ref:3629292; PMID:16675951
PR:P08152-2 mEGR2/iso:Short	located_in	GO:0005634 nucleus	MGI_ref:3629292; PMID:16675951