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Protein Ontology report - gamma-secretase subunit APH-1A
PR:000004129 - http://purl.obolibrary.org/obo/PR_000004129
 
  Protein Forms      
Ontology Information Show OBO stanza
  PRO ID
PR:000004129   
  PRO namegamma-secretase subunit APH-1A 
  Synonyms
PRO-Short-label: EXACT:APH1A
Gene-based: RELATED:CGI-78 | PSF | UNQ579/PRO1141
Other: EXACT:APH-1a | Aph-1alpha | presenilin-stabilization factor
  Definition"A protein that is a translation product of the human APH1A gene or a 1:1 ortholog thereof." [PRO:DNx] 
  CommentRequested by=Alzforum. 
  PRO Categorygene 
  ParentPR:000000001 protein
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Gene1                                                  Organism-Gene 2                                        
         Sequence2                                                  Organism-Sequence 5                                        
         Modification0                                                  Organism-Modification 3                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Protein Forms Switch to Compact View   

Category  
PRO ID
Name
Short Name
Definition
Ann. Has Annotation?

Comp. In Complex?
gene


PR:000004129
gamma-secretase subunit APH-1A
APH1A
"A protein that is a translation product of the human APH1A gene or a 1:1 ortholog thereof." [PRO:DNx]

organism-gene


PR:Q8BVF7
gamma-secretase subunit APH-1A (mouse)
mAPH1A
"A gamma-secretase subunit APH-1A that is encoded in the genome of mouse." [OMA:Q8BVF7, PRO:DNx]

organism-sequence


PR:Q8BVF7-1
gamma-secretase subunit APH-1A isoform 1 (mouse)
mAPH1A/iso:1
"A gamma-secretase subunit APH-1A isoform 1 that is encoded in the genome of mouse." [PRO:DNx]

organism-sequence


PR:Q8BVF7-2
gamma-secretase subunit APH-1A isoform 2 (mouse)
mAPH1A/iso:2
"A gamma-secretase subunit APH-1A isoform 2 that is encoded in the genome of mouse." [PRO:DNx]

organism-gene


PR:Q96BI3
gamma-secretase subunit APH-1A (human)
hAPH1A
"A gamma-secretase subunit APH-1A that is encoded in the genome of human." [PRO:DNx, UniProtKB:Q96BI3]

organism-sequence


PR:Q96BI3-1
gamma-secretase subunit APH-1A isoform 1 (human)
hAPH1A/iso:1
"A gamma-secretase subunit APH-1A isoform 1 that is encoded in the genome of human." [PRO:DNx]

organism-sequence


PR:Q96BI3-2
gamma-secretase subunit APH-1A isoform 2 (human)
hAPH1A/iso:2
"A gamma-secretase subunit APH-1A isoform 2 that is encoded in the genome of human." [PRO:DNx]

organism-sequence


PR:Q96BI3-3
gamma-secretase subunit APH-1A isoform h3 (human)
hAPH1A/iso:h3
"A gamma-secretase subunit APH-1A (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q96BI3-3." [PRO:DNx, UniProtKB:Q96BI3]

organism-modification


PR:000065326
gamma-secretase subunit APH-1A deaminated 1 (human)
hAPH1A/Deam:1
"A gamma-secretase subunit APH-1A (human) that has been deaminated on the residue at the position equivalent to Gln-83 of the amino acid sequence represented by UniProtKB:Q96BI3-1. Example: UniProtKB:Q96BI3-1, Gln-83, MOD:00685." [IEDB_epitope:1751020, PRO:DNx]

organism-modification


PR:000079251
gamma-secretase subunit APH-1A deaminated 2 (human)
hAPH1A/Deam:2
"A gamma-secretase subunit APH-1A (human) that has been deaminated on the residue at the position equivalent to Gln-68 of the amino acid sequence represented by UniProtKB:Q96BI3-1. Example: UniProtKB:Q96BI3-1, Gln-68, MOD:00685." [IEDB_epitope:432513, PRO:DNx]

organism-modification


PR:000079907
gamma-secretase subunit APH-1A methylated 1 (human)
hAPH1A/Me:1
"A gamma-secretase subunit APH-1A (human) that has been methylated on the residue at the position equivalent to Cys-9 of the amino acid sequence represented by UniProtKB:Q96BI3-1. Example: UniProtKB:Q96BI3-1, Cys-9, MOD:00660." [IEDB_epitope:1057301, PRO:DNx]

sequence


PR:000042444
gamma-secretase subunit APH-1A isoform 1
APH1A/iso:1
"A gamma-secretase subunit APH-1A that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q96BI3-1 or a 1:1 ortholog thereof." [PRO:DNx]

organism-sequence


PR:Q8BVF7-1
gamma-secretase subunit APH-1A isoform 1 (mouse)
mAPH1A/iso:1
"A gamma-secretase subunit APH-1A isoform 1 that is encoded in the genome of mouse." [PRO:DNx]

organism-sequence


PR:Q96BI3-1
gamma-secretase subunit APH-1A isoform 1 (human)
hAPH1A/iso:1
"A gamma-secretase subunit APH-1A isoform 1 that is encoded in the genome of human." [PRO:DNx]

sequence


PR:000042445
gamma-secretase subunit APH-1A isoform 2
APH1A/iso:2
"A gamma-secretase subunit APH-1A that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q96BI3-2 or a 1:1 ortholog thereof." [PRO:DNx]

organism-sequence


PR:Q8BVF7-2
gamma-secretase subunit APH-1A isoform 2 (mouse)
mAPH1A/iso:2
"A gamma-secretase subunit APH-1A isoform 2 that is encoded in the genome of mouse." [PRO:DNx]

organism-sequence


PR:Q96BI3-2
gamma-secretase subunit APH-1A isoform 2 (human)
hAPH1A/iso:2
"A gamma-secretase subunit APH-1A isoform 2 that is encoded in the genome of human." [PRO:DNx]