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Protein Ontology report - apolipoprotein E
PR:000004155 - http://purl.obolibrary.org/obo/PR_000004155
 
  Protein Forms      
Ontology Information Show OBO stanza
  PRO ID
PR:000004155   
  PRO nameapolipoprotein E 
  Synonyms
PRO-Short-label: EXACT:APOE
Other: EXACT:apo-E
  Definition"A protein that is a translation product of the human APOE gene or a 1:1 ortholog thereof." [PRO:DNx] 
  PRO Categorygene 
  ParentPR:000000001 protein
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Gene1                                                  Organism-Gene 4                                        
         Sequence0                                                  Organism-Sequence 0                                        
         Modification1                                                  Organism-Modification 18                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Protein Forms Switch to Compact View   

Category  

PRO ID

Name

Short Name

Definition

Ann. Has Annotation?

Comp. In Complex?
gene



PR:000004155

apolipoprotein E

APOE


"A protein that is a translation product of the human APOE gene or a 1:1 ortholog thereof." [PRO:DNx]


organism-gene



PR:P02649

apolipoprotein E (human)

hAPOE


"An apolipoprotein E that is encoded in the genome of human." [PRO:DNx, UniProtKB:P02649]


organism-modification



PR:000046364

apolipoprotein E, signal peptide removed form (human)

hAPOE/SigPep-


"An apolipoprotein E (human) that has had the signal peptide removed. UniProtKB:P02649, 19-317." [PRO:DNx, Reactome:R-HSA-174615, Reactome:R-HSA-174646, Reactome:R-HSA-174651, Reactome:R-HSA-174766, Reactome:R-HSA-174804, Reactome:R-HSA-2429687, Reactome:R-HSA-3221641]


organism-modification



PR:000061688

apolipoprotein E, signal peptide removed phosphorylated form (human)

hAPOE/SigPep-/PhosRes+


"An apolipoprotein E (human) that has had the signal peptide removed and that includes at least one phosphorylated residue. UniProtKB:P02649, 19-317, MOD:00696." [PRO:DNx, Reactome:R-HSA-8956980]


organism-modification



PR:000062648

apolipoprotein E sequence variant S112R, signal peptide removed form (human)

hAPOE/var:S112R/SigPep-


"An apolipoprotein E (human) that has an Arg residue at the position equivalent to Ser-112 of the amino acid sequence represented by UniProtKB:P02649 and that has had the signal peptide removed. UniProtKB:P02649, 19-317, Ser-112, CHEBI:29952." [PRO:DNx, Reactome:R-HSA-9711070]


organism-modification



PR:000052484

apolipoprotein E O-glycosylated 1 (human)

hAPOE/OGlyco:1


"An apolipoprotein E (human) that has been O-glycosylated at the residue equivalent to Ser-215 of the amino acid sequence represented by UniProtKB:P02649-1, in which the glycan composition is represented by GlyTouCan:G43417UB. Example: UniProtKB:P02649-1, Ser-215, MOD:00002~GNO:G43417UB." [GlyGen:P02649-1, PMID:30459171, PRO:DNx]


organism-modification



PR:000052485

apolipoprotein E O-glycosylated 2 (human)

hAPOE/OGlyco:2


"An apolipoprotein E (human) that has been O-glycosylated at the residue equivalent to Ser-308 of the amino acid sequence represented by UniProtKB:P02649-1, in which the glycan composition is represented by GlyTouCan:G29068FM. Example: UniProtKB:P02649-1, Ser-308, MOD:00002~GNO:G29068FM." [GlyGen:P02649-1, PMID:30459171, PRO:DNx]


organism-modification



PR:000052486

apolipoprotein E O-glycosylated 3 (human)

hAPOE/OGlyco:3


"An apolipoprotein E (human) that has been O-glycosylated at the residue equivalent to Ser-308 of the amino acid sequence represented by UniProtKB:P02649-1, in which the glycan composition is represented by GlyTouCan:G43417UB. Example: UniProtKB:P02649-1, Ser-308, MOD:00002~GNO:G43417UB." [GlyGen:P02649-1, PMID:23234360, PMID:30459171, PRO:DNx]


organism-modification



PR:000052487

apolipoprotein E O-glycosylated 4 (human)

hAPOE/OGlyco:4


"An apolipoprotein E (human) that has been O-glycosylated at the residue equivalent to Ser-314 of the amino acid sequence represented by UniProtKB:P02649-1, in which the glycan composition is represented by GlyTouCan:G43417UB. Example: UniProtKB:P02649-1, Ser-314, MOD:00002~GNO:G43417UB." [GlyGen:P02649-1, PMID:23234360, PRO:DNx]


organism-modification



PR:000052488

apolipoprotein E O-glycosylated 5 (human)

hAPOE/OGlyco:5


"An apolipoprotein E (human) that has been O-glycosylated at the residue equivalent to Thr-212 of the amino acid sequence represented by UniProtKB:P02649-1, in which the glycan composition is represented by GlyTouCan:G29068FM. Example: UniProtKB:P02649-1, Thr-212, MOD:00005~GNO:G29068FM." [GlyGen:P02649-1, PMID:30459171, PRO:DNx]


organism-modification



PR:000052489

apolipoprotein E O-glycosylated 6 (human)

hAPOE/OGlyco:6


"An apolipoprotein E (human) that has been O-glycosylated at the residue equivalent to Thr-212 of the amino acid sequence represented by UniProtKB:P02649-1, in which the glycan composition is represented by GlyTouCan:G43417UB. Example: UniProtKB:P02649-1, Thr-212, MOD:00005~GNO:G43417UB." [GlyGen:P02649-1, PMID:23234360, PMID:30459171, PRO:DNx]


organism-modification



PR:000052490

apolipoprotein E O-glycosylated 7 (human)

hAPOE/OGlyco:7


"An apolipoprotein E (human) that has been O-glycosylated at the residue equivalent to Thr-212 of the amino acid sequence represented by UniProtKB:P02649-1, in which the glycan composition is represented by GlyTouCan:G53434XO. Example: UniProtKB:P02649-1, Thr-212, MOD:00005~GNO:G53434XO." [GlyGen:P02649-1, PMID:23234360, PRO:DNx]


organism-modification



PR:000052491

apolipoprotein E O-glycosylated 8 (human)

hAPOE/OGlyco:8


"An apolipoprotein E (human) that has been O-glycosylated at the residue equivalent to Thr-26 of the amino acid sequence represented by UniProtKB:P02649-1, in which the glycan composition is represented by GlyTouCan:G43417UB. Example: UniProtKB:P02649-1, Thr-26, MOD:00005~GNO:G43417UB." [GlyGen:P02649-1, PMID:23234360, PRO:DNx]


organism-modification



PR:000052492

apolipoprotein E O-glycosylated 9 (human)

hAPOE/OGlyco:9


"An apolipoprotein E (human) that has been O-glycosylated at the residue equivalent to Thr-307 of the amino acid sequence represented by UniProtKB:P02649-1, in which the glycan composition is represented by GlyTouCan:G43417UB. Example: UniProtKB:P02649-1, Thr-307, MOD:00005~GNO:G43417UB." [GlyGen:P02649-1, PMID:30459171, PRO:DNx]


organism-modification



PR:000052493

apolipoprotein E O-glycosylated 10 (human)

hAPOE/OGlyco:10


"An apolipoprotein E (human) that has been O-glycosylated at the residue equivalent to Thr-36 of the amino acid sequence represented by UniProtKB:P02649-1, in which the glycan composition is represented by GlyTouCan:G43417UB. Example: UniProtKB:P02649-1, Thr-36, MOD:00005~GNO:G43417UB." [GlyGen:P02649-1, PMID:23234360, PMID:30459171, PRO:DNx]


organism-modification



PR:000061688

apolipoprotein E, signal peptide removed phosphorylated form (human)

hAPOE/SigPep-/PhosRes+


"An apolipoprotein E (human) that has had the signal peptide removed and that includes at least one phosphorylated residue. UniProtKB:P02649, 19-317, MOD:00696." [PRO:DNx, Reactome:R-HSA-8956980]


organism-modification



PR:000068329

apolipoprotein E cysteinylated 1 (human)

hAPOE/Cyst:1


"An apolipoprotein E (human) that has been cysteinylated on the residue at the position equivalent to Cys-130 of the amino acid sequence represented by UniProtKB:P02649. UniProtKB:P02649, Cys-130, MOD:00765." [IEDB_epitope:2117409, PRO:DNx]


organism-modification



PR:000082081

apolipoprotein E citrullinated 1 (human)

hAPOE/Cit:1


"An apolipoprotein E (human) that has been citrullinated on the residue at the position equivalent to Arg-199 of the amino acid sequence represented by UniProtKB:P02649. UniProtKB:P02649, Arg-199, MOD:00219." [IEDB_epitope:178128, PRO:DNx]


organism-gene



PR:P02650

apolipoprotein E (rat)

rAPOE


"An apolipoprotein E that is encoded in the genome of rat." [OMA:P02650, PRO:DNx]


organism-gene



PR:P08226

apolipoprotein E (mouse)

mAPOE


"An apolipoprotein E that is encoded in the genome of mouse." [OMA:P08226, PRO:DNx]


organism-modification



PR:000072020

apolipoprotein E deaminated 1 (mouse)

mAPOE/Deam:1


"An apolipoprotein E (mouse) that has been deaminated on the residue at the position equivalent to Asn-310 of the amino acid sequence represented by UniProtKB:P08226. UniProtKB:P08226, Asn-310, MOD:00684." [IEDB_epitope:2135778, IEDB_epitope:2136812, PRO:DNx]


organism-modification



PR:000074025

apolipoprotein E deaminated 2 (mouse)

mAPOE/Deam:2


"An apolipoprotein E (mouse) that has been deaminated on the residue at the position equivalent to Gln-91 of the amino acid sequence represented by UniProtKB:P08226. UniProtKB:P08226, Gln-91, MOD:00685." [IEDB_epitope:2136012, IEDB_epitope:2136434, PRO:DNx]


organism-modification



PR:000074621

apolipoprotein E deaminated 3 (mouse)

mAPOE/Deam:3


"An apolipoprotein E (mouse) that has been deaminated on the residue at the position equivalent to Gln-311 of the amino acid sequence represented by UniProtKB:P08226. UniProtKB:P08226, Gln-311, MOD:00685." [IEDB_epitope:2135780, PRO:DNx]


organism-gene



PR:Q03247

apolipoprotein E (cow)

cow-APOE


"An apolipoprotein E that is encoded in the genome of cow." [OMA:Q03247, PRO:DNx]


modification



PR:000019028

apolipoprotein E, signal peptide removed form

APOE/SigPep-


"An apolipoprotein E that has had the signal peptide removed." [PRO:DNx]


organism-modification



PR:000046364

apolipoprotein E, signal peptide removed form (human)

hAPOE/SigPep-


"An apolipoprotein E (human) that has had the signal peptide removed. UniProtKB:P02649, 19-317." [PRO:DNx, Reactome:R-HSA-174615, Reactome:R-HSA-174646, Reactome:R-HSA-174651, Reactome:R-HSA-174766, Reactome:R-HSA-174804, Reactome:R-HSA-2429687, Reactome:R-HSA-3221641]


organism-modification



PR:000061688

apolipoprotein E, signal peptide removed phosphorylated form (human)

hAPOE/SigPep-/PhosRes+


"An apolipoprotein E (human) that has had the signal peptide removed and that includes at least one phosphorylated residue. UniProtKB:P02649, 19-317, MOD:00696." [PRO:DNx, Reactome:R-HSA-8956980]


organism-modification



PR:000062648

apolipoprotein E sequence variant S112R, signal peptide removed form (human)

hAPOE/var:S112R/SigPep-


"An apolipoprotein E (human) that has an Arg residue at the position equivalent to Ser-112 of the amino acid sequence represented by UniProtKB:P02649 and that has had the signal peptide removed. UniProtKB:P02649, 19-317, Ser-112, CHEBI:29952." [PRO:DNx, Reactome:R-HSA-9711070]