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Protein Ontology report - baculoviral IAP repeat-containing protein 5
PR:000004753 - http://purl.obolibrary.org/obo/PR_000004753
 
  Protein Forms  Annotations      
Ontology Information Show OBO stanza
  PRO ID
PR:000004753   
  PRO namebaculoviral IAP repeat-containing protein 5 
  Synonyms
PRO-Short-label: EXACT:BIRC5
Gene-based: RELATED:API4 | IAP4
Other: EXACT:apoptosis inhibitor 4 | apoptosis inhibitor survivin | TIAP
  Definition"A protein that is a translation product of the human BIRC5 gene or a 1:1 ortholog thereof." [PRO:DNx] 
  PRO Categorygene 
  ParentPR:000000001 protein
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Gene1                                                  Organism-Gene 3                                        
         Sequence2                                                  Organism-Sequence 10                                        
         Modification2                                                  Organism-Modification 5                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Related Cross References

  Db identifiers
IUPHARobj:2795
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Protein Forms Switch to Compact View   

Category  
PRO ID
Name
Short Name
Definition
Ann. Has Annotation?

Comp. In Complex?
gene


PR:000004753
baculoviral IAP repeat-containing protein 5
BIRC5
"A protein that is a translation product of the human BIRC5 gene or a 1:1 ortholog thereof." [PRO:DNx]

organism-gene


PR:O15392
baculoviral IAP repeat-containing protein 5 (human)
hBIRC5
"A baculoviral IAP repeat-containing protein 5 that is encoded in the genome of human." [PMID:12719470, PMID:15917996, PMID:20929775, PRO:KER]
Yes
organism-sequence


PR:O15392-1
baculoviral IAP repeat-containing protein 5 isoform 1 (human)
hBIRC5/iso:1
"A baculoviral IAP repeat-containing protein 5 isoform 1 that is encoded in the genome of human." [PMID:10626797, UniProtKB:O15392]

organism-modification


PR:000026283
baculoviral IAP repeat-containing protein 5 isoform 1 phosphorylated 1 (human)
hBIRC5/iso:1/Phos:1
"A baculoviral IAP repeat-containing protein 5 isoform 1 phosphorylated 1 in human. UniProtKB:O15392-1, Thr-34, MOD:00047." [PMID:11069302, PRO:CNA]

organism-modification


PR:000026285
baculoviral IAP repeat-containing protein 5 isoform 1 phosphorylated 2 (human)
hBIRC5/iso:1/Phos:2
"A baculoviral IAP repeat-containing protein 5 isoform 1 phosphorylated 2 in human. UniProtKB:O15392-1, Thr-117, MOD:00047." [PMID:14610074, PRO:CNA]

organism-sequence


PR:O15392-2
baculoviral IAP repeat-containing protein 5 isoform 2 (human)
hBIRC5/iso:2
"A baculoviral IAP repeat-containing protein 5 isoform 2 that is encoded in the genome of human." [PMID:10626797, UniProtKB:O15392]

organism-sequence


PR:O15392-3
baculoviral IAP repeat-containing protein 5 isoform h3 (human)
hBIRC5/iso:h3
"A baculoviral IAP repeat-containing protein 5 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:O15392-3." [PRO:DNx, UniProtKB:O15392]

organism-sequence


PR:O15392-4
baculoviral IAP repeat-containing protein 5 isoform h4 (human)
hBIRC5/iso:h4
"A baculoviral IAP repeat-containing protein 5 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:O15392-4." [PRO:DNx, UniProtKB:O15392]

organism-sequence


PR:O15392-5
baculoviral IAP repeat-containing protein 5 isoform h5 (human)
hBIRC5/iso:h5
"A baculoviral IAP repeat-containing protein 5 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:O15392-5." [PRO:DNx, UniProtKB:O15392]

organism-sequence


PR:O15392-6
baculoviral IAP repeat-containing protein 5 isoform h6 (human)
hBIRC5/iso:h6
"A baculoviral IAP repeat-containing protein 5 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:O15392-6." [PRO:DNx, UniProtKB:O15392]

organism-sequence


PR:O15392-7
baculoviral IAP repeat-containing protein 5 isoform h7 (human)
hBIRC5/iso:h7
"A baculoviral IAP repeat-containing protein 5 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:O15392-7." [PRO:DNx, UniProtKB:O15392]

organism-modification


PR:000064644
baculoviral IAP repeat-containing protein 5 ubiquitinated form (human)
hBIRC5/UbiqLys+
"A baculoviral IAP repeat-containing protein 5 (human) that includes at least one ubiquitinated lysine. UniProtKB:O15392, MOD:01148." [PRO:DNx, Reactome:R-HSA-8955933]

organism-modification


PR:000067014
baculoviral IAP repeat-containing protein 5 methylated 1 (human)
hBIRC5/Me:1
"A baculoviral IAP repeat-containing protein 5 (human) that has been methylated on the residue at the position equivalent to Cys-46 of the amino acid sequence represented by UniProtKB:O15392-1. Example: UniProtKB:O15392-1, Cys-46, MOD:00660." [IEDB_epitope:997978, PRO:DNx]

organism-modification


PR:000073616
baculoviral IAP repeat-containing protein 5 cysteinylated 1 (human)
hBIRC5/Cyst:1
"A baculoviral IAP repeat-containing protein 5 (human) that has been cysteinylated on the residue at the position equivalent to Cys-46 of the amino acid sequence represented by UniProtKB:O15392-1. Example: UniProtKB:O15392-1, Cys-46, MOD:00765." [IEDB_epitope:1561472, PRO:DNx]

organism-gene


PR:O70201
baculoviral IAP repeat-containing protein 5 (mouse)
mBIRC5
"A baculoviral IAP repeat-containing protein 5 that is encoded in the genome of mouse." [OMA:O70201, PRO:DNx]

organism-sequence


PR:O70201-1
baculoviral IAP repeat-containing protein 5 isoform 1 (mouse)
mBIRC5/iso:1
"A baculoviral IAP repeat-containing protein 5 isoform 1 that is encoded in the genome of mouse." [PRO:CNx]

organism-sequence


PR:O70201-2
baculoviral IAP repeat-containing protein 5 isoform m2 (mouse)
mBIRC5/iso:m2
"A baculoviral IAP repeat-containing protein 5 (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:O70201-2." [PRO:DNx, UniProtKB:O70201]

organism-sequence


PR:O70201-3
baculoviral IAP repeat-containing protein 5 isoform m3 (mouse)
mBIRC5/iso:m3
"A baculoviral IAP repeat-containing protein 5 (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:O70201-3." [PRO:DNx, UniProtKB:O70201]

organism-gene


PR:Q9JHY7
baculoviral IAP repeat-containing protein 5 (rat)
rBIRC5
"A baculoviral IAP repeat-containing protein 5 that is encoded in the genome of rat." [OMA:Q9JHY7, PRO:DNx]

sequence


PR:000026278
baculoviral IAP repeat-containing protein 5 isoform 1
BIRC5/iso:1
"A baculoviral IAP repeat-containing protein 5 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:O15392-1 or a 1:1 ortholog thereof." [PRO:CNx]

organism-sequence


PR:O15392-1
baculoviral IAP repeat-containing protein 5 isoform 1 (human)
hBIRC5/iso:1
"A baculoviral IAP repeat-containing protein 5 isoform 1 that is encoded in the genome of human." [PMID:10626797, UniProtKB:O15392]

organism-modification


PR:000026283
baculoviral IAP repeat-containing protein 5 isoform 1 phosphorylated 1 (human)
hBIRC5/iso:1/Phos:1
"A baculoviral IAP repeat-containing protein 5 isoform 1 phosphorylated 1 in human. UniProtKB:O15392-1, Thr-34, MOD:00047." [PMID:11069302, PRO:CNA]

organism-modification


PR:000026285
baculoviral IAP repeat-containing protein 5 isoform 1 phosphorylated 2 (human)
hBIRC5/iso:1/Phos:2
"A baculoviral IAP repeat-containing protein 5 isoform 1 phosphorylated 2 in human. UniProtKB:O15392-1, Thr-117, MOD:00047." [PMID:14610074, PRO:CNA]

organism-sequence


PR:O70201-1
baculoviral IAP repeat-containing protein 5 isoform 1 (mouse)
mBIRC5/iso:1
"A baculoviral IAP repeat-containing protein 5 isoform 1 that is encoded in the genome of mouse." [PRO:CNx]

modification


PR:000026282
baculoviral IAP repeat-containing protein 5 isoform 1 phosphorylated 1
BIRC5/iso:1/Phos:1
"A baculoviral IAP repeat-containing protein 5 isoform 1 that has been phosphorylated by CDK1 (cyclin-dependent kinase p34cdc2). Example: UniProtKB:O15392-1, Thr-34, MOD:00047." [PMID:11069302, PRO:CNA]

organism-modification


PR:000026283
baculoviral IAP repeat-containing protein 5 isoform 1 phosphorylated 1 (human)
hBIRC5/iso:1/Phos:1
"A baculoviral IAP repeat-containing protein 5 isoform 1 phosphorylated 1 in human. UniProtKB:O15392-1, Thr-34, MOD:00047." [PMID:11069302, PRO:CNA]

modification


PR:000026284
baculoviral IAP repeat-containing protein 5 isoform 1 phosphorylated 2
BIRC5/iso:1/Phos:2
"A baculoviral IAP repeat-containing protein 5 isoform 1 that has been phosphorylated by aurora-B kinase in its carboxyl alpha-helical coil. Example: UniProtKB:O15392-1, Thr-117, MOD:00047." [PMID:14610074, PRO:CNA]

organism-modification


PR:000026285
baculoviral IAP repeat-containing protein 5 isoform 1 phosphorylated 2 (human)
hBIRC5/iso:1/Phos:2
"A baculoviral IAP repeat-containing protein 5 isoform 1 phosphorylated 2 in human. UniProtKB:O15392-1, Thr-117, MOD:00047." [PMID:14610074, PRO:CNA]

sequence


PR:000026280
baculoviral IAP repeat-containing protein 5 isoform 2
BIRC5/iso:2
"A baculoviral IAP repeat-containing protein 5 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:O15392-2 or a 1:1 ortholog thereof." [PRO:CNx]

organism-sequence


PR:O15392-2
baculoviral IAP repeat-containing protein 5 isoform 2 (human)
hBIRC5/iso:2
"A baculoviral IAP repeat-containing protein 5 isoform 2 that is encoded in the genome of human." [PMID:10626797, UniProtKB:O15392]

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Functional Annotation (PRO-centric view) Switch to GO Centric View   
PRO Term GO Annotation Evidence
PR:O15392 hBIRC5 acts_upstream_of_or_withinGO:0071459 protein localization to chromosome, centromeric region PMID:20929775
located_inGO:0000779 condensed chromosome, centromeric region PMID:12719470; PMID:15917996
GO:0030496 midbody PMID:15917996
GO:0051233 spindle midzone PMID:15917996