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Protein Ontology report - outer kinetochore KNL1 complex subunit KNL1
PR:000005050 - http://purl.obolibrary.org/obo/PR_000005050
 
  Protein Forms  Annotations      
Ontology Information Show OBO stanza
  PRO ID
PR:000005050   
  PRO nameouter kinetochore KNL1 complex subunit KNL1 
  Synonyms
PRO-Short-label: EXACT:KNL1
Gene-based: RELATED:CASC5 | KIAA1570
Other: EXACT:AF15q14 | ALL1-fused gene from chromosome 15q14 | blinkin | Bub-linking kinetochore protein | cancer susceptibility candidate gene 5 protein | cancer/testis antigen 29 | CT29 | kinetochore scaffold 1 | kinetochore-null protein 1 | protein CASC5 | protein D40/AF15q14
  Definition"A protein that is a translation product of the human KNL1 gene or a 1:1 ortholog thereof." [PRO:DNx] 
  PRO Categorygene 
  ParentPR:000000001 protein
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Gene1                                                  Organism-Gene 3                                        
         Sequence2                                                  Organism-Sequence 6                                        
         Modification2                                                  Organism-Modification 6                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Protein Forms  Switch to Extended View   

Category  
PRO Form Name
Short Name
Ann. Has Annotation?

Comp. In Complex?
gene


PR:000005050 outer kinetochore KNL1 complex subunit KNL1
KNL1

organism-gene


PR:D3Z896 protein LOC100911204 (rat)
rKNL1

organism-gene


PR:Q66JQ7 outer kinetochore KNL1 complex subunit KNL1 (mouse)
mKNL1

organism-sequence


PR:Q66JQ7-1 outer kinetochore KNL1 complex subunit KNL1 isoform m1 (mouse)
mKNL1/iso:m1

organism-sequence


PR:Q66JQ7-2 outer kinetochore KNL1 complex subunit KNL1 isoform m2 (mouse)
mKNL1/iso:m2

organism-gene


PR:Q8NG31 outer kinetochore KNL1 complex subunit KNL1 (human)
hKNL1
Yes
organism-sequence


PR:Q8NG31-1 outer kinetochore KNL1 complex subunit KNL1 isoform 1 (human)
hKNL1/iso:1

organism-sequence


PR:Q8NG31-2 outer kinetochore KNL1 complex subunit KNL1 isoform 2 (human)
hKNL1/iso:2

organism-modification


PR:000035558 outer kinetochore KNL1 complex subunit KNL1 isoform 2 phosphorylated 1 (human)
hKNL1/iso:2/Phos:1
Yes
organism-modification


PR:000035560 outer kinetochore KNL1 complex subunit KNL1 isoform 2 unphosphorylated form (human)
hKNL1/iso:2/PhosRes-

organism-sequence


PR:Q8NG31-3 outer kinetochore KNL1 complex subunit KNL1 isoform h3 (human)
hKNL1/iso:h3

organism-sequence


PR:Q8NG31-4 outer kinetochore KNL1 complex subunit KNL1 isoform h4 (human)
hKNL1/iso:h4

organism-modification


PR:000071007 outer kinetochore KNL1 complex subunit KNL1 methylated 1 (human)
hKNL1/Me:1

organism-modification


PR:000071490 outer kinetochore KNL1 complex subunit KNL1 cysteinylated 1 (human)
hKNL1/Cyst:1

organism-modification


PR:000077771 outer kinetochore KNL1 complex subunit KNL1 phosphorylated 1 (human)
hKNL1/Phos:1

organism-modification


PR:000083702 outer kinetochore KNL1 complex subunit KNL1 deaminated 1 (human)
hKNL1/Deam:1

sequence


PR:000035553 outer kinetochore KNL1 complex subunit KNL1 isoform 1
KNL1/iso:1

organism-sequence


PR:Q8NG31-1 outer kinetochore KNL1 complex subunit KNL1 isoform 1 (human)
hKNL1/iso:1

sequence


PR:000035555 outer kinetochore KNL1 complex subunit KNL1 isoform 2
KNL1/iso:2

organism-sequence


PR:Q8NG31-2 outer kinetochore KNL1 complex subunit KNL1 isoform 2 (human)
hKNL1/iso:2

organism-modification


PR:000035558 outer kinetochore KNL1 complex subunit KNL1 isoform 2 phosphorylated 1 (human)
hKNL1/iso:2/Phos:1
Yes
organism-modification


PR:000035560 outer kinetochore KNL1 complex subunit KNL1 isoform 2 unphosphorylated form (human)
hKNL1/iso:2/PhosRes-

modification


PR:000035557 outer kinetochore KNL1 complex subunit KNL1 isoform 2 phosphorylated 1
KNL1/iso:2/Phos:1

organism-modification


PR:000035558 outer kinetochore KNL1 complex subunit KNL1 isoform 2 phosphorylated 1 (human)
hKNL1/iso:2/Phos:1
Yes
modification


PR:000035559 outer kinetochore KNL1 complex subunit KNL1 isoform 2 unphosphorylated form
KNL1/iso:2/PhosRes-

organism-modification


PR:000035560 outer kinetochore KNL1 complex subunit KNL1 isoform 2 unphosphorylated form (human)
hKNL1/iso:2/PhosRes-

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Functional Annotation (PRO-centric view) Switch to GO Centric View   
PRO Term GO Annotation Evidence
PR:000035558 hKNL1/iso:2/Phos:1
UniProtKB:Q8NG31-2, Thr-875/Thr-1075/Thr-1089/Thr-1129/Thr-1154/Thr-1167, MOD:00047|Ser-1022/Ser-1037, MOD:00046		 acts_upstream_of_or_withinincreased GO:0034501 protein localization to kinetochore relative to PR:000035560 hKNL1/iso:2/PhosRes- PMID:22660415
PR:Q8NG31 hKNL1 enablesGO:0005515 protein binding with PR:O14777 HEC BioGRID:BG-697221
GO:0005515 protein binding with PR:O43683 BUB1 BioGRID:BG-697221
GO:0005515 protein binding with PR:O60566 BUB1B BioGRID:BG-697221
located_inGO:0000776 kinetochore PMID:20624902