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Protein Ontology report - G1/S-specific cyclin-D1
PR:000005121 - http://purl.obolibrary.org/obo/PR_000005121
 
  Protein Forms  Complex  Annotations      
Ontology Information Show OBO stanza
  PRO ID
PR:000005121   
  PRO nameG1/S-specific cyclin-D1 
  Synonyms
PRO-Short-label: EXACT:CCND1
Gene-based: RELATED:BCL1 | Cyl-1 | PRAD1
Other: EXACT:B-cell lymphoma 1 protein | BCL-1 | BCL-1 oncogene | PRAD1 oncogene
  Definition"A cyclin-D that is a translation product of the human CCND1 gene or a 1:1 ortholog thereof." [PRO:DNx] 
  PRO Categorygene 
  ParentPR:000050022 cyclin-D
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Gene1                                                  Organism-Gene 5                                        
         Sequence1                                                  Organism-Sequence 3                                        
         Modification1                                                  Organism-Modification 11                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Protein Forms  Switch to Extended View   

Category  
PRO Form Name
Short Name
Ann. Has Annotation?

Comp. In Complex?
gene


PR:000005121 G1/S-specific cyclin-D1
CCND1

Yes
organism-gene


PR:P24385 G1/S-specific cyclin-D1 (human)
hCCND1

Yes
organism-sequence


PR:P24385-1 G1/S-specific cyclin-D1 isoform 1 (human)
hCCND1/iso:1

organism-modification


PR:000027132 G1/S-specific cyclin-D1 phosphorylated 1 (human)
hCCND1/Phos:1
Yes
Yes
organism-modification


PR:000037511 G1/S-specific cyclin-D1 unphosphorylated 1 (human)
hCCND1/UnPhos:1
Yes
organism-modification


PR:000037512 G1/S-specific cyclin-D1 phosphorylated and multi-ubiquitinated 1 (human)
hCCND1/PhosUbiq:1

organism-modification


PR:000068517 G1/S-specific cyclin-D1 deaminated 1 (human)
hCCND1/Deam:1

organism-modification


PR:000068576 G1/S-specific cyclin-D1 methylated 1 (human)
hCCND1/Me:1

organism-modification


PR:000070754 G1/S-specific cyclin-D1 deaminated 2 (human)
hCCND1/Deam:2

organism-modification


PR:000072927 G1/S-specific cyclin-D1 cysteinylated 1 (human)
hCCND1/Cyst:1

organism-modification


PR:000075931 G1/S-specific cyclin-D1 cysteinylated 2 (human)
hCCND1/Cyst:2

organism-modification


PR:000076531 G1/S-specific cyclin-D1 cysteinylated 3 (human)
hCCND1/Cyst:3

organism-modification


PR:000080333 G1/S-specific cyclin-D1 phosphorylated 2 (human)
hCCND1/Phos:2

organism-gene


PR:P25322 G1/S-specific cyclin-D1 (mouse)
mCCND1

organism-sequence


PR:P25322-1 G1/S-specific cyclin-D1 isoform 1 (mouse)
mCCND1/iso:1

organism-modification


PR:000046156 G1/S-specific cyclin-D1 phosphorylated 1 (mouse)
mCCND1/Phos:1

organism-gene


PR:P39948 G1/S-specific cyclin-D1 (rat)
rCCND1

organism-sequence


PR:P39948-1 G1/S-specific cyclin-D1 isoform 1 (rat)
rCCND1/iso:1

organism-gene


PR:P55169 G1/S-specific cyclin-D1 (chicken)
chick-CCND1

organism-gene


PR:Q90459 G1/S-specific cyclin-D1 (zebrafish)
z-CCND1

sequence


PR:000039111 G1/S-specific cyclin-D1 isoform 1
CCND1/iso:1

organism-sequence


PR:P24385-1 G1/S-specific cyclin-D1 isoform 1 (human)
hCCND1/iso:1

organism-sequence


PR:P25322-1 G1/S-specific cyclin-D1 isoform 1 (mouse)
mCCND1/iso:1

organism-sequence


PR:P39948-1 G1/S-specific cyclin-D1 isoform 1 (rat)
rCCND1/iso:1

modification


PR:000027131 G1/S-specific cyclin-D1 phosphorylated 1
CCND1/Phos:1

Yes
organism-modification


PR:000027132 G1/S-specific cyclin-D1 phosphorylated 1 (human)
hCCND1/Phos:1
Yes
Yes
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CCND1 forms found in complexes   

CCND1 Component
 Complexes
PR:000005121 CCND1 PR:000026740 cyclin D1:Cdk4
PR:000027131 CCND1/Phos:1 PR:000027140 cyclin D1:Cdk4 complex phosphorylated 1
PR:000027132 hCCND1/Phos:1 PR:000027150 cyclin D1:Cdk4 complex phosphorylated 1 (human)
PR:P24385 hCCND1 PR:000026741 cyclin D1:Cdk4 (human)
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Functional Annotation (PRO-centric view) Switch to GO Centric View   
PRO Term GO Annotation Evidence
PR:000027132 hCCND1/Phos:1
UniProtKB:P24385, Thr-286, MOD:00047		 enablesincreased GO:0005515 protein binding with PR:000037513 SCF(FBX4-alphaB crystallin) complex (human) PMID:17407548
PR:000037511 hCCND1/UnPhos:1
UniProtKB:P24385, Thr-286, PR:000026291		 associated_with_disease_progressionDO:162 cancer PMID:17407548