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Protein Ontology report - cell division cycle protein 20 homolog
PR:000005188 - http://purl.obolibrary.org/obo/PR_000005188
 
  Protein Forms  Complex  Annotations      
Ontology Information Show OBO stanza
  PRO ID
PR:000005188   
  PRO namecell division cycle protein 20 homolog 
  Synonyms
PRO-Short-label: EXACT:CDC20
Other: EXACT:mmCdc20 | p55CDC
  Definition"A protein that is a translation product of the human CDC20 gene or a 1:1 ortholog thereof." [PRO:DNx] 
  PRO Categorygene 
  ParentPR:000000001 protein
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Gene1                                                  Organism-Gene 6                                        
         Sequence1                                                  Organism-Sequence 3                                        
         Modification5                                                  Organism-Modification 11                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Protein Forms  Switch to Extended View   

Category  
PRO Form Name
Short Name
Ann. Has Annotation?

Comp. In Complex?
gene


PR:000005188 cell division cycle protein 20 homolog
CDC20

organism-gene


PR:P26309 APC/C activator protein CDC20 (yeast)
yCDC20

organism-gene


PR:P78972 WD repeat-containing protein slp1 (Schizosaccharomyces pombe 972h-)
Spom972h-CDC20

organism-gene


PR:Q12834 cell division cycle protein 20 homolog (human)
hCDC20
Yes
Yes
organism-sequence


PR:Q12834-1 cell division cycle protein 20 homolog isoform 1 (human)
hCDC20/iso:1

organism-modification


PR:000035369 cell division cycle protein 20 homolog unphosphorylated form (human)
hCDC20/PhosRes-
Yes
organism-modification


PR:000035371 cell division cycle protein 20 homolog phosphorylated 1 (human)
hCDC20/Phos:1
Yes
organism-modification


PR:000035440 cell division cycle protein 20 homolog phosphorylated 2 (human)
hCDC20/Phos:2

organism-modification


PR:000035442 cell division cycle protein 20 homolog phosphorylated 3 (human)
hCDC20/Phos:3
Yes
organism-modification


PR:000046658 cell division cycle protein 20 homolog ubiquitinated form (human)
hCDC20/UbiqLys+

organism-modification


PR:000066860 cell division cycle protein 20 homolog cysteinylated 1 (human)
hCDC20/Cyst:1

organism-modification


PR:000076113 cell division cycle protein 20 homolog methylated 1 (human)
hCDC20/Me:1

organism-modification


PR:000079638 cell division cycle protein 20 homolog methylated 2 (human)
hCDC20/Me:2

organism-modification


PR:000082105 cell division cycle protein 20 homolog deaminated 1 (human)
hCDC20/Deam:1

organism-gene


PR:Q62623 cell division cycle protein 20 homolog (rat)
rCDC20

organism-sequence


PR:Q62623-1 cell division cycle protein 20 homolog isoform 1 (rat)
rCDC20/iso:1

organism-gene


PR:Q6DFD4 cell division cycle protein 20 homolog (frog)
frog-CDC20

Yes
organism-modification


PR:000035444 cell division cycle protein 20 homolog phosphorylated 4 (frog)
frog-CDC20/Phos:4
Yes
organism-modification


PR:000035628 cell division cycle protein 20 homolog unphosphorylated form (frog)
frog-CDC20/PhosRes-

organism-gene


PR:Q9JJ66 cell division cycle protein 20 homolog (mouse)
mCDC20

organism-sequence


PR:Q9JJ66-1 cell division cycle protein 20 homolog isoform 1 (mouse)
mCDC20/iso:1

sequence


PR:000040367 cell division cycle protein 20 homolog isoform 1
CDC20/iso:1

organism-sequence


PR:Q12834-1 cell division cycle protein 20 homolog isoform 1 (human)
hCDC20/iso:1

organism-sequence


PR:Q62623-1 cell division cycle protein 20 homolog isoform 1 (rat)
rCDC20/iso:1

organism-sequence


PR:Q9JJ66-1 cell division cycle protein 20 homolog isoform 1 (mouse)
mCDC20/iso:1

modification


PR:000035368 cell division cycle protein 20 homolog unphosphorylated form
CDC20/PhosRes-

organism-modification


PR:000035369 cell division cycle protein 20 homolog unphosphorylated form (human)
hCDC20/PhosRes-
Yes
organism-modification


PR:000035628 cell division cycle protein 20 homolog unphosphorylated form (frog)
frog-CDC20/PhosRes-

modification


PR:000035370 cell division cycle protein 20 homolog phosphorylated 1
CDC20/Phos:1

organism-modification


PR:000035371 cell division cycle protein 20 homolog phosphorylated 1 (human)
hCDC20/Phos:1
Yes
modification


PR:000035439 cell division cycle protein 20 homolog phosphorylated 2
CDC20/Phos:2

organism-modification


PR:000035440 cell division cycle protein 20 homolog phosphorylated 2 (human)
hCDC20/Phos:2

modification


PR:000035441 cell division cycle protein 20 homolog phosphorylated 3
CDC20/Phos:3

organism-modification


PR:000035442 cell division cycle protein 20 homolog phosphorylated 3 (human)
hCDC20/Phos:3
Yes
modification


PR:000035443 cell division cycle protein 20 homolog phosphorylated 4
CDC20/Phos:4

organism-modification


PR:000035444 cell division cycle protein 20 homolog phosphorylated 4 (frog)
frog-CDC20/Phos:4
Yes
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CDC20 forms found in complexes   

CDC20 Component
 Complexes
PR:Q12834 hCDC20 PR:000035511 BUB1B:BUB3:MAD2:CDC20 complex (human)
PR:000035575 BUB1B:CDC20 complex (human)
PR:Q6DFD4 frog-CDC20 PR:000035512 BUB1B:BUB3:MAD2:CDC20 complex (frog)
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Functional Annotation (PRO-centric view) Switch to GO Centric View   
PRO Term GO Annotation Evidence
PR:000035369 hCDC20/PhosRes- acts_upstream_of_or_withinGO:0031577 spindle checkpoint signaling PMID:15525512
enablesGO:0004842 ubiquitin-protein transferase activity PMID:15525512
GO:0005515 protein binding with PR:Q13257 hMAD2L1 PMID:15525512
GO:0005515 protein binding PMID:15525512
located_inGO:0000776 kinetochore PMID:15525512
PR:000035371 hCDC20/Phos:1
UniProtKB:Q12834, Ser-41/Ser-72/Ser-92/Ser-153/Ser-161, MOD:00046|Thr-157, MOD:00047		 acts_upstream_of_or_withinincreased GO:0031577 spindle checkpoint signaling relative to PR:000035369 cdc20 unphosphorylated (human) PMID:15525512
enablesdecreased GO:0004842 ubiquitin-protein transferase activity relative to PR:000035369 cdc20 unphosphorylated (human) PMID:15525512
GO:0005515 protein binding with PR:Q13257 hMAD2L1 PMID:15525512
GO:0005515 protein binding PMID:15525512
located_inGO:0000776 kinetochore PMID:15525512
PR:000035442 hCDC20/Phos:3
Potential sites Ser-41, Ser-408, Ser-452, Thr-55, Thr-59, Thr-70, Thr-106, Thr-157		 enablesdecreased GO:0005515 protein binding with PR:O60566 BUB1B PMID:22566641
PR:000035444 frog-CDC20/Phos:4
UniProtKB:Q6DFD4, Ser-50, MOD:00046|Thr-64/Thr-68/Thr-79, MOD:00047		 acts_upstream_of_or_withinincreased GO:0031577 spindle checkpoint signaling relative to PR:000035628 cdc20 unphosphorylated (frog) PMID:12855955
enablesincreased GO:0005515 protein binding with PR:O60566 BUB1B PMID:12855955
increased GO:0005515 protein binding with PR:P79935 frog-MAD2L1 PMID:12855955
PR:Q12834 hCDC20 enablesGO:0005515 protein binding with PR:O60566 BUB1B PMID:20624902
GO:0005515 protein binding with PR:Q13257 hMAD2L1 PMID:20624902