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Protein Ontology report - complement factor B
PR:000005374 - http://purl.obolibrary.org/obo/PR_000005374
 
  Protein Forms      
Ontology Information Show OBO stanza
  PRO ID
PR:000005374   
  PRO namecomplement factor B 
  Synonyms
PRO-Short-label: EXACT:CFB
Gene-based: RELATED:BF | BFD | H2-Bf
Other: EXACT:GBG | glycine-rich beta glycoprotein | PBF2 | properdin factor B
RELATED:C3/C5 convertase
  Definition"A protein that is a translation product of the human CFB gene or a 1:1 ortholog thereof." [PRO:DNx] 
  PRO Categorygene 
  ParentPR:000000001 protein
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Gene1                                                  Organism-Gene 2                                        
         Sequence0                                                  Organism-Sequence 2                                        
         Modification2                                                  Organism-Modification 6                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Related Cross References

  Db identifiers
IUPHARobj:2339
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Protein Forms Switch to Compact View   

Category  

PRO ID

Name

Short Name

Definition

Ann. Has Annotation?

Comp. In Complex?
gene



PR:000005374

complement factor B

CFB


"A protein that is a translation product of the human CFB gene or a 1:1 ortholog thereof." [PRO:DNx]


organism-gene



PR:P00751

complement factor B (human)

hCFB


"A complement factor B that is encoded in the genome of human." [PRO:DNx, UniProtKB:P00751]


organism-sequence



PR:P00751-1

complement factor B isoform h1 (human)

hCFB/iso:h1


"A complement factor B (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P00751-1." [PRO:DNx, UniProtKB:P00751]


organism-sequence



PR:P00751-2

complement factor B isoform h2 (human)

hCFB/iso:h2


"A complement factor B (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P00751-2." [PRO:DNx, UniProtKB:P00751]


organism-modification



PR:000046693

complement factor B, signal peptide removed form (human)

hCFB/SigPep-


"A complement factor B (human) that has had the signal peptide removed. UniProtKB:P00751, 26-764." [PRO:DNx, Reactome:R-HSA-173738]


organism-modification



PR:000051363

complement factor B N-glycosylated 1 (human)

hCFB/NGlyco:1


"A complement factor B (human) that has been N-glycosylated at the residue equivalent to Asn-285 of the amino acid sequence represented by UniProtKB:P00751-1, in which the glycan composition is represented by GlyTouCan:G00912UN. Example: UniProtKB:P00751-1, Asn-285, MOD:00160~GNO:G00912UN." [GlyGen:P00751-1, PMID:29671580, PRO:DNx]


organism-modification



PR:000051364

complement factor B O-glycosylated 1 (human)

hCFB/OGlyco:1


"A complement factor B (human) that has been O-glycosylated at the residue equivalent to Thr-25 of the amino acid sequence represented by UniProtKB:P00751-1, in which the glycan composition is represented by GlyTouCan:G53434XO. Example: UniProtKB:P00751-1, Thr-25, MOD:00005~GNO:G53434XO." [GlyGen:P00751-1, PMID:30459171, PRO:DNx]


organism-modification



PR:000051365

complement factor B O-glycosylated 2 (human)

hCFB/OGlyco:2


"A complement factor B (human) that has been O-glycosylated at the residue equivalent to Thr-26 of the amino acid sequence represented by UniProtKB:P00751-1, in which the glycan composition is represented by GlyTouCan:G43417UB. Example: UniProtKB:P00751-1, Thr-26, MOD:00005~GNO:G43417UB." [GlyGen:P00751-1, PMID:30459171, PRO:DNx]


organism-modification



PR:000073212

complement factor B phosphorylated 1 (human)

hCFB/Phos:1


"A complement factor B (human) that has been phosphorylated on the residue at the position equivalent to Ser-709 of the amino acid sequence represented by UniProtKB:P00751-1. Example: UniProtKB:P00751-1, Ser-709, MOD:00046." [IEDB_epitope:2148354, PRO:DNx]


organism-modification



PR:000080735

complement factor B deaminated 1 (human)

hCFB/Deam:1


"A complement factor B (human) that has been deaminated on the residue at the position equivalent to Gln-626 of the amino acid sequence represented by UniProtKB:P00751-1. Example: UniProtKB:P00751-1, Gln-626, MOD:00685." [IEDB_epitope:1990556, PRO:DNx]


organism-gene



PR:P04186

complement factor B (mouse)

mCFB


"A complement factor B that is encoded in the genome of mouse." [OMA:P04186, PRO:DNx]


modification



PR:000019307

complement factor B, signal peptide removed form

CFB/SigPep-


"A complement factor B that has had the signal peptide removed." [PRO:DNx]


organism-modification



PR:000046693

complement factor B, signal peptide removed form (human)

hCFB/SigPep-


"A complement factor B (human) that has had the signal peptide removed. UniProtKB:P00751, 26-764." [PRO:DNx, Reactome:R-HSA-173738]


modification



PR:000019308

complement factor B proteolytic cleavage product

CFB/ClvPrd


"A complement factor B that has been processed by proteolytic cleavage." [PRO:DNx]