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Protein Ontology report - cathepsin D
PR:000006025 - http://purl.obolibrary.org/obo/PR_000006025
 
  Protein Forms      
Ontology Information Show OBO stanza
  PRO ID
PR:000006025   
  PRO namecathepsin D 
  Synonyms
PRO-Short-label: EXACT:CTSD
Gene-based: RELATED:CPSD
  Definition"A cathepsin-like protease that is a translation product of the human CTSD gene or a 1:1 ortholog thereof." [PRO:DNx] 
  PRO Categorygene 
  ParentPR:000040662 cathepsin-like protease
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Gene1                                                  Organism-Gene 7                                        
         Sequence0                                                  Organism-Sequence 0                                        
         Modification2                                                  Organism-Modification 12                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Related Cross References

  Db identifiers
IUPHARobj:2345
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Protein Forms Switch to Compact View   

Category  

PRO ID

Name

Short Name

Definition

Ann. Has Annotation?

Comp. In Complex?
gene



PR:000006025

cathepsin D

CTSD


"A cathepsin-like protease that is a translation product of the human CTSD gene or a 1:1 ortholog thereof." [PRO:DNx]


organism-gene



PR:O76856

cathepsin D (Dictyostelium discoideum)

Dicty-CTSD


"A cathepsin D that is encoded in the genome of Dictyostelium discoideum." [OMA:O76856, PRO:DNx]


organism-gene



PR:P07339

cathepsin D (human)

hCTSD


"A cathepsin D that is encoded in the genome of human." [PRO:DNx, UniProtKB:P07339]


organism-modification



PR:000053727

cathepsin D O-glycosylated 1 (human)

hCTSD/OGlyco:1


"A cathepsin D (human) that has been O-glycosylated at the residue equivalent to Thr-63 of the amino acid sequence represented by UniProtKB:P07339-1, in which the glycan composition is represented by GlyTouCan:G43417UB. Example: UniProtKB:P07339-1, Thr-63, MOD:00005~GNO:G43417UB." [GlyGen:P07339-1, PMID:30459171, PRO:DNx]


organism-modification



PR:000065667

cathepsin D glutathionylated 1 (human)

hCTSD/SGlt:1


"A cathepsin D (human) that has been glutathionylated on the residue at the position equivalent to Cys-329 of the amino acid sequence represented by UniProtKB:P07339. UniProtKB:P07339, Cys-329, MOD:00234." [IEDB_epitope:422431, IEDB_epitope:422432, PRO:DNx]


organism-modification



PR:000074474

cathepsin D cysteinylated 1 (human)

hCTSD/Cyst:1


"A cathepsin D (human) that has been cysteinylated on the residue at the position equivalent to Cys-117 of the amino acid sequence represented by UniProtKB:P07339. UniProtKB:P07339, Cys-117, MOD:00765." [IEDB_epitope:1563036, IEDB_epitope:1563037, IEDB_epitope:2118358, PRO:DNx]


organism-modification



PR:000076876

cathepsin D cysteinylated 2 (human)

hCTSD/Cyst:2


"A cathepsin D (human) that has been cysteinylated on the residue at the position equivalent to Cys-329 of the amino acid sequence represented by UniProtKB:P07339. UniProtKB:P07339, Cys-329, MOD:00765." [IEDB_epitope:2117893, IEDB_epitope:2117894, IEDB_epitope:2122206, IEDB_epitope:2122207, IEDB_epitope:2125877, IEDB_epitope:773727, PRO:DNx]


organism-modification



PR:000079343

cathepsin D deaminated 1 (human)

hCTSD/Deam:1


"A cathepsin D (human) that has been deaminated on the residue at the position equivalent to Asn-217 of the amino acid sequence represented by UniProtKB:P07339. UniProtKB:P07339, Asn-217, MOD:00684." [IEDB_epitope:1850728, PRO:DNx]


organism-modification



PR:000085149

cathepsin D cysteinylated 3 (human)

hCTSD/Cyst:3


"A cathepsin D (human) that has been cysteinylated on the residue at the position equivalent to Cys-366 of the amino acid sequence represented by UniProtKB:P07339. UniProtKB:P07339, Cys-366, MOD:00765." [IEDB_epitope:2130721, PRO:DNx]


organism-gene



PR:P18242

cathepsin D (mouse)

mCTSD


"A cathepsin D that is encoded in the genome of mouse." [PRO:DNx]


organism-gene



PR:P24268

cathepsin D (rat)

rCTSD


"A cathepsin D that is encoded in the genome of rat." [PANTHER:PTHR13683:SF84, PRO:DNx]


organism-modification



PR:000058851

cathepsin D N-glycosylated 1 (rat)

rCTSD/NGlyco:1


"A cathepsin D (rat) that has been N-glycosylated at the residue equivalent to Asn-134 of the amino acid sequence represented by UniProtKB:P24268-1, in which the glycan composition is represented by GlyTouCan:G02815KT. Example: UniProtKB:P24268-1, Asn-134, MOD:00160~GNO:G02815KT." [GlyGen:P24268-1, PMID:24090084, PRO:DNx]


organism-modification



PR:000058852

cathepsin D N-glycosylated 2 (rat)

rCTSD/NGlyco:2


"A cathepsin D (rat) that has been N-glycosylated at the residue equivalent to Asn-134 of the amino acid sequence represented by UniProtKB:P24268-1, in which the glycan composition is represented by GlyTouCan:G41247ZX. Example: UniProtKB:P24268-1, Asn-134, MOD:00160~GNO:G41247ZX." [GlyGen:P24268-1, PMID:24090084, PRO:DNx]


organism-modification



PR:000058853

cathepsin D N-glycosylated 3 (rat)

rCTSD/NGlyco:3


"A cathepsin D (rat) that has been N-glycosylated at the residue equivalent to Asn-134 of the amino acid sequence represented by UniProtKB:P24268-1, in which the glycan structure is represented by GlyTouCan:G55220VL. Example: UniProtKB:P24268-1, Asn-134, MOD:00160~GNO:G55220VL." [GlyGen:P24268-1, PMID:24090084, PRO:DNx]


organism-modification



PR:000058854

cathepsin D N-glycosylated 4 (rat)

rCTSD/NGlyco:4


"A cathepsin D (rat) that has been N-glycosylated at the residue equivalent to Asn-134 of the amino acid sequence represented by UniProtKB:P24268-1, in which the glycan structure is represented by GlyTouCan:G80966KZ. Example: UniProtKB:P24268-1, Asn-134, MOD:00160~GNO:G80966KZ." [GlyGen:P24268-1, PMID:24090084, PRO:DNx]


organism-modification



PR:000058855

cathepsin D N-glycosylated 5 (rat)

rCTSD/NGlyco:5


"A cathepsin D (rat) that has been N-glycosylated at the residue equivalent to Asn-258 of the amino acid sequence represented by UniProtKB:P24268-1, in which the glycan composition is represented by GlyTouCan:G02815KT. Example: UniProtKB:P24268-1, Asn-258, MOD:00160~GNO:G02815KT." [GlyGen:P24268-1, PMID:24090084, PRO:DNx]


organism-modification



PR:000058856

cathepsin D N-glycosylated 6 (rat)

rCTSD/NGlyco:6


"A cathepsin D (rat) that has been N-glycosylated at the residue equivalent to Asn-258 of the amino acid sequence represented by UniProtKB:P24268-1, in which the glycan composition is represented by GlyTouCan:G41247ZX. Example: UniProtKB:P24268-1, Asn-258, MOD:00160~GNO:G41247ZX." [GlyGen:P24268-1, PMID:24090084, PRO:DNx]


organism-gene



PR:P32834

aspartic proteinase sxa1 (Schizosaccharomyces pombe 972h-)

Spom972h-CTSD


"A cathepsin D that is encoded in the genome of Schizosaccharomyces pombe 972h-." [OMA:P32834, PRO:DNx]


organism-gene



PR:Q05744

cathepsin D (chicken)

chick-CTSD


"A cathepsin D that is encoded in the genome of chicken." [PRO:DNx]


organism-gene



PR:Q21966

aspartic protease 4 (worm)

CTSD (worm)


"A cathepsin D that is encoded in the genome of worm." [OMA:Q21966, PRO:DNx]


modification



PR:000019560

cathepsin D, signal peptide removed form

CTSD/SigPep-


"A cathepsin D that has had the signal peptide removed." [PRO:DNx]


modification



PR:000019561

cathepsin D proteolytic cleavage product

CTSD/ClvPrd


"A cathepsin D that has been processed by proteolytic cleavage." [PRO:DNx]