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Protein Ontology report - sphingolipid Delta(4)-desaturase/C4-monooxygenase DES2
PR:000006414 - http://purl.obolibrary.org/obo/PR_000006414
 
  Protein Forms  Annotations      
Ontology Information Show OBO stanza
  PRO ID
PR:000006414   
  PRO namesphingolipid Delta(4)-desaturase/C4-monooxygenase DES2 
  Synonyms
PRO-Short-label: EXACT:DEGS2
Gene-based: RELATED:C14orf66
Other: EXACT:degenerative spermatocyte homolog 2 | sphingolipid 4-desaturase | sphingolipid C4-monooxygenase | sphingolipid Delta(4)-desaturase/C4-hydroxylase DES2
  Definition"A protein that is a translation product of the human DEGS2 gene or a 1:1 ortholog thereof." [PRO:DNx] 
  PRO Categorygene 
  ParentPR:000000001 protein
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Gene1                                                  Organism-Gene 3                                        
         Sequence2                                                  Organism-Sequence 3                                        
         Modification0                                                  Organism-Modification 1                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Related Cross References

  Db identifiers
IUPHARobj:2485
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Protein Forms  Switch to Extended View   

Category  
PRO Form Name
Short Name
Ann. Has Annotation?

Comp. In Complex?
gene


PR:000006414 sphingolipid Delta(4)-desaturase/C4-monooxygenase DES2
DEGS2

organism-gene


PR:Q564G3 sphingolipid Delta(4)-desaturase/C4-monooxygenase DES2 (rat)
rDEGS2

organism-gene


PR:Q6QHC5 sphingolipid Delta(4)-desaturase/C4-monooxygenase DES2 (human)
hDEGS2

organism-sequence


PR:Q6QHC5-1 sphingolipid Delta(4)-desaturase/C4-monooxygenase DES2 isoform 1 (human)
hDEGS2/iso:1

organism-modification


PR:000061533 sphingolipid Delta(4)-desaturase/C4-monooxygenase DES2, initiator methionine removed form (human)
hDEGS2/InitMet-

organism-gene


PR:Q8R2F2 sphingolipid Delta(4)-desaturase/C4-monooxygenase DES2 (mouse)
mDEGS2
Yes
organism-sequence


PR:Q8R2F2-1 sphingolipid Delta(4)-desaturase/C4-hydroxylase DES2 isoform 1 (mouse)
mDEGS2/iso:1
Yes
organism-sequence


PR:Q8R2F2-2 sphingolipid Delta(4)-desaturase/C4-hydroxylase DES2 isoform 2 (mouse)
mDEGS2/iso:2

sequence


PR:000022016 sphingolipid Delta(4)-desaturase/C4-monooxygenase DES2 isoform 1
DEGS2/iso:1
Yes
organism-sequence


PR:Q6QHC5-1 sphingolipid Delta(4)-desaturase/C4-monooxygenase DES2 isoform 1 (human)
hDEGS2/iso:1

organism-sequence


PR:Q8R2F2-1 sphingolipid Delta(4)-desaturase/C4-hydroxylase DES2 isoform 1 (mouse)
mDEGS2/iso:1
Yes
sequence


PR:000022017 sphingolipid Delta(4)-desaturase/C4-monooxygenase DES2 isoform 2
DEGS2/iso:2

organism-sequence


PR:Q8R2F2-2 sphingolipid Delta(4)-desaturase/C4-hydroxylase DES2 isoform 2 (mouse)
mDEGS2/iso:2

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Functional Annotation (PRO-centric view) Switch to GO Centric View   
PRO Term GO Annotation Evidence
PR:000022016 DEGS2/iso:1 acts_upstream_of_or_withinGO:0006667 sphinganine metabolic process MGI_ref:3694278; PMID:16571104
GO:0046513 ceramide biosynthetic process MGI_ref:3694278; PMID:16571104
enablesGO:0102772 sphingolipid C4-monooxygenase activity MGI_ref:3694278; PMID:16571104
GO:0102772 sphingolipid C4-monooxygenase activity MGI_ref:3694278; PMID:16571104
PR:Q8R2F2 mDEGS2 acts_upstream_of_or_withinGO:0006667 sphinganine metabolic process PMID:11937514
GO:0030148 sphingolipid biosynthetic process PMID:11937514
enablesGO:0042284 sphingolipid delta-4 desaturase activity PMID:11937514
PR:Q8R2F2-1 mDEGS2/iso:1 acts_upstream_of_or_withinGO:0006667 sphinganine metabolic process MGI_ref:3694278; PMID:16571104
GO:0046513 ceramide biosynthetic process MGI_ref:3694278; PMID:16571104
enablesGO:0102772 sphingolipid C4-monooxygenase activity MGI_ref:3056825; PMID:15474011
GO:0102772 sphingolipid C4-monooxygenase activity MGI_ref:3056825; PMID:15474011