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Documentation
Protein Ontology report - sphingolipid Delta(4)-desaturase/C4-monooxygenase DES2
PR:000006414 -
http://purl.obolibrary.org/obo/PR_000006414
Protein Forms
Annotations
Ontology Information
Show OBO stanza
PRO ID
PR:000006414
PRO name
sphingolipid Delta(4)-desaturase/C4-monooxygenase DES2
Synonyms
PRO-Short-label
:
EXACT:
DEGS2
Gene-based
:
RELATED:
C14orf66
Other
:
EXACT:
degenerative spermatocyte homolog 2 | sphingolipid 4-desaturase | sphingolipid C4-monooxygenase | sphingolipid Delta(4)-desaturase/C4-hydroxylase DES2
Definition
"A protein that is a translation product of the human DEGS2 gene or a 1:1 ortholog thereof." [PRO:DNx]
PRO Category
gene
Parent
PR:000000001
protein
Terms by PRO Category
Organism-Independent
Organism-Specific
Category
Number of Terms
Category
Number of Terms
Gene
1
Organism-Gene
3
Sequence
2
Organism-Sequence
3
Modification
0
Organism-Modification
1
Term Hierarchy
Visualization
DAG:
OLS:
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Related Cross References
Db identifiers
IUPHARobj:2485
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Protein Forms
Switch to
Extended View
Category
PRO Form Name
Short Name
Ann.
Has Annotation?
Comp.
In Complex?
gene
PR:000006414
sphingolipid Delta(4)-desaturase/C4-monooxygenase DES2
DEGS2
organism-gene
PR:Q564G3
sphingolipid Delta(4)-desaturase/C4-monooxygenase DES2 (rat)
rDEGS2
organism-gene
PR:Q6QHC5
sphingolipid Delta(4)-desaturase/C4-monooxygenase DES2 (human)
hDEGS2
organism-sequence
PR:Q6QHC5-1
sphingolipid Delta(4)-desaturase/C4-monooxygenase DES2 isoform 1 (human)
hDEGS2/iso:1
organism-modification
PR:000061533
sphingolipid Delta(4)-desaturase/C4-monooxygenase DES2, initiator methionine removed form (human)
hDEGS2/InitMet-
organism-gene
PR:Q8R2F2
sphingolipid Delta(4)-desaturase/C4-monooxygenase DES2 (mouse)
mDEGS2
Yes
organism-sequence
PR:Q8R2F2-1
sphingolipid Delta(4)-desaturase/C4-hydroxylase DES2 isoform 1 (mouse)
mDEGS2/iso:1
Yes
organism-sequence
PR:Q8R2F2-2
sphingolipid Delta(4)-desaturase/C4-hydroxylase DES2 isoform 2 (mouse)
mDEGS2/iso:2
sequence
PR:000022016
sphingolipid Delta(4)-desaturase/C4-monooxygenase DES2 isoform 1
DEGS2/iso:1
Yes
organism-sequence
PR:Q6QHC5-1
sphingolipid Delta(4)-desaturase/C4-monooxygenase DES2 isoform 1 (human)
hDEGS2/iso:1
organism-sequence
PR:Q8R2F2-1
sphingolipid Delta(4)-desaturase/C4-hydroxylase DES2 isoform 1 (mouse)
mDEGS2/iso:1
Yes
sequence
PR:000022017
sphingolipid Delta(4)-desaturase/C4-monooxygenase DES2 isoform 2
DEGS2/iso:2
organism-sequence
PR:Q8R2F2-2
sphingolipid Delta(4)-desaturase/C4-hydroxylase DES2 isoform 2 (mouse)
mDEGS2/iso:2
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Functional Annotation (GO-centric view)
Switch to
PRO Centric View
Biological Process GO Term
Protein Forms & Complexes
Evidence
GO:0006667
sphinganine metabolic process
PR:000022016
DEGS2/iso:1
MGI_ref:3694278;
PMID:16571104
PR:Q8R2F2
mDEGS2
PMID:11937514
PR:Q8R2F2-1
mDEGS2/iso:1
MGI_ref:3694278;
PMID:16571104
GO:0030148
sphingolipid biosynthetic process
PR:Q8R2F2
mDEGS2
PMID:11937514
GO:0046513
ceramide biosynthetic process
PR:000022016
DEGS2/iso:1
MGI_ref:3694278;
PMID:16571104
PR:Q8R2F2-1
mDEGS2/iso:1
MGI_ref:3694278;
PMID:16571104
Molecular Function GO Term
Protein Forms & Complexes
Evidence
GO:0042284
sphingolipid delta-4 desaturase activity
PR:Q8R2F2
mDEGS2
PMID:11937514
GO:0102772
sphingolipid C4-monooxygenase activity
PR:000022016
DEGS2/iso:1
MGI_ref:3694278;
PMID:16571104
PR:000022016
DEGS2/iso:1
MGI_ref:3694278;
PMID:16571104
PR:000022016
DEGS2/iso:1
MGI_ref:3694278;
PMID:16571104
PR:000022016
DEGS2/iso:1
MGI_ref:3694278;
PMID:16571104
PR:000022016
DEGS2/iso:1
MGI_ref:3694278;
PMID:16571104
PR:000022016
DEGS2/iso:1
MGI_ref:3694278;
PMID:16571104
PR:000022016
DEGS2/iso:1
MGI_ref:3694278;
PMID:16571104
PR:000022016
DEGS2/iso:1
MGI_ref:3694278;
PMID:16571104
PR:000022016
DEGS2/iso:1
MGI_ref:3694278;
PMID:16571104
PR:000022016
DEGS2/iso:1
MGI_ref:3694278;
PMID:16571104
PR:Q8R2F2-1
mDEGS2/iso:1
MGI_ref:3056825;
PMID:15474011
PR:Q8R2F2-1
mDEGS2/iso:1
MGI_ref:3056825;
PMID:15474011
PR:Q8R2F2-1
mDEGS2/iso:1
MGI_ref:3056825;
PMID:15474011
PR:Q8R2F2-1
mDEGS2/iso:1
MGI_ref:3056825;
PMID:15474011
PR:Q8R2F2-1
mDEGS2/iso:1
MGI_ref:3056825;
PMID:15474011
PR:Q8R2F2-1
mDEGS2/iso:1
MGI_ref:3056825;
PMID:15474011
