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Protein Ontology report - disrupted in schizophrenia 1 protein
PR:000006494 - http://purl.obolibrary.org/obo/PR_000006494
 
  Protein Forms  Annotations      
Ontology Information Show OBO stanza
  PRO ID
PR:000006494   
  PRO namedisrupted in schizophrenia 1 protein 
  Synonyms
PRO-Short-label: EXACT:DISC1
Gene-based: RELATED:KIAA0457
  Definition"A protein that is a translation product of the human DISC1 gene or a 1:1 ortholog thereof." [PRO:DNx] 
  PRO Categorygene 
  ParentPR:000000001 protein
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Gene1                                                  Organism-Gene 3                                        
         Sequence1                                                  Organism-Sequence 17                                        
         Modification2                                                  Organism-Modification 2                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Protein Forms  Switch to Extended View   

Category  
PRO Form Name
Short Name
Ann. Has Annotation?

Comp. In Complex?
gene


PR:000006494 disrupted in schizophrenia 1 protein
DISC1

organism-gene


PR:Q810H6 disrupted in schizophrenia 1 homolog (rat)
rDISC1

organism-sequence


PR:Q810H6-1 disrupted in schizophrenia 1 homolog isoform r1 (rat)
rDISC1/iso:r1

organism-sequence


PR:Q810H6-2 disrupted in schizophrenia 1 homolog isoform r2 (rat)
rDISC1/iso:r2

organism-gene


PR:Q811T9 disrupted in schizophrenia 1 homolog (mouse)
mDISC1

organism-sequence


PR:Q811T9-1 disrupted in schizophrenia 1 protein isoform 1 (mouse)
mDISC1/iso:1

organism-modification


PR:000035602 disrupted in schizophrenia 1 protein isoform 1 phosphorylated 1 (mouse)
mDISC1/iso:1/Phos:1
Yes
organism-modification


PR:000035654 disrupted in schizophrenia 1 protein isoform 1 unphosphorylated form (mouse)
mDISC1/iso:1/PhosRes-
Yes
organism-sequence


PR:Q811T9-2 disrupted in schizophrenia 1 protein isoform 2 (mouse)
mDISC1/iso:2

organism-sequence


PR:Q811T9-3 disrupted in schizophrenia 1 protein isoform 3 (mouse)
mDISC1/iso:3

organism-sequence


PR:Q811T9-4 disrupted in schizophrenia 1 protein isoform 4 (mouse)
mDISC1/iso:4

organism-gene


PR:Q9NRI5 disrupted in schizophrenia 1 protein (human)
hDISC1

organism-sequence


PR:Q9NRI5-1 disrupted in schizophrenia 1 protein isoform h1 (human)
hDISC1/iso:h1

organism-sequence


PR:Q9NRI5-10 disrupted in schizophrenia 1 protein isoform h10 (human)
hDISC1/iso:h10

organism-sequence


PR:Q9NRI5-11 disrupted in schizophrenia 1 protein isoform h11 (human)
hDISC1/iso:h11

organism-sequence


PR:Q9NRI5-2 disrupted in schizophrenia 1 protein isoform h2 (human)
hDISC1/iso:h2

organism-sequence


PR:Q9NRI5-3 disrupted in schizophrenia 1 protein isoform h3 (human)
hDISC1/iso:h3

organism-sequence


PR:Q9NRI5-4 disrupted in schizophrenia 1 protein isoform h4 (human)
hDISC1/iso:h4

organism-sequence


PR:Q9NRI5-5 disrupted in schizophrenia 1 protein isoform h5 (human)
hDISC1/iso:h5

organism-sequence


PR:Q9NRI5-6 disrupted in schizophrenia 1 protein isoform h6 (human)
hDISC1/iso:h6

organism-sequence


PR:Q9NRI5-7 disrupted in schizophrenia 1 protein isoform h7 (human)
hDISC1/iso:h7

organism-sequence


PR:Q9NRI5-8 disrupted in schizophrenia 1 protein isoform h8 (human)
hDISC1/iso:h8

organism-sequence


PR:Q9NRI5-9 disrupted in schizophrenia 1 protein isoform h9 (human)
hDISC1/iso:h9

sequence


PR:000035601 disrupted in schizophrenia 1 protein isoform 1
DISC1/iso:1

organism-sequence


PR:Q811T9-1 disrupted in schizophrenia 1 protein isoform 1 (mouse)
mDISC1/iso:1

organism-modification


PR:000035602 disrupted in schizophrenia 1 protein isoform 1 phosphorylated 1 (mouse)
mDISC1/iso:1/Phos:1
Yes
organism-modification


PR:000035654 disrupted in schizophrenia 1 protein isoform 1 unphosphorylated form (mouse)
mDISC1/iso:1/PhosRes-
Yes
modification


PR:000035600 disrupted in schizophrenia 1 protein isoform 1 phosphorylated 1
DISC1/iso:1/Phos:1

organism-modification


PR:000035602 disrupted in schizophrenia 1 protein isoform 1 phosphorylated 1 (mouse)
mDISC1/iso:1/Phos:1
Yes
modification


PR:000035653 disrupted in schizophrenia 1 protein isoform 1 unphosphorylated form
DISC1/iso:1/PhosRes-

organism-modification


PR:000035654 disrupted in schizophrenia 1 protein isoform 1 unphosphorylated form (mouse)
mDISC1/iso:1/PhosRes-
Yes
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Functional Annotation (PRO-centric view) Switch to GO Centric View   
PRO Term GO Annotation Evidence
PR:000035602 mDISC1/iso:1/Phos:1
UniProtKB:Q811T9-1, Ser-710, MOD:00046		 acts_upstream_of_or_withinGO:0008104 intracellular protein localization MGI_ref:5002731; PMID:21471969
enablesGO:0005515 protein binding with PR:Q3V3N7 Bardet-Biedl syndrome 1 protein homolog (mouse) MGI_ref:5002731; PMID:21471969
located_inGO:0005813 centrosome MGI_ref:5002731; PMID:21471969
PR:000035654 mDISC1/iso:1/PhosRes- acts_upstream_of_or_withinGO:0060070 canonical Wnt signaling pathway MGI_ref:5002731; PMID:21471969
enablesGO:0005515 protein binding with PR:Q9WV60 GSK-3 beta (mouse) MGI_ref:5002731; PMID:21471969