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Protein Ontology report - segment polarity protein dishevelled homolog DVL-2
PR:000006767 - http://purl.obolibrary.org/obo/PR_000006767
 
  Protein Forms  Annotations      
Ontology Information Show OBO stanza
  PRO ID
PR:000006767   
  PRO namesegment polarity protein dishevelled homolog DVL-2 
  Synonyms
PRO-Short-label: EXACT:DVL2
Other: EXACT:dishevelled-2 | DSH homolog 2
  Definition"A protein that is a translation product of the human DVL2 gene or a 1:1 ortholog thereof." [PRO:DNx] 
  PRO Categorygene 
  ParentPR:000000001 protein
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Gene1                                                  Organism-Gene 2                                        
         Sequence1                                                  Organism-Sequence 2                                        
         Modification3                                                  Organism-Modification 7                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Protein Forms  Switch to Extended View   

Category  
PRO Form Name
Short Name
Ann. Has Annotation?

Comp. In Complex?
gene


PR:000006767 segment polarity protein dishevelled homolog DVL-2
DVL2

organism-gene


PR:O14641 segment polarity protein dishevelled homolog DVL-2 (human)
hDVL2
Yes
organism-sequence


PR:O14641-1 segment polarity protein dishevelled homolog DVL-2 isoform 1 (human)
hDVL2/iso:1

organism-modification


PR:000035550 segment polarity protein dishevelled homolog DVL-2 unphosphorylated form (human)
hDVL2/PhosRes-
Yes
organism-modification


PR:000047225 segment polarity protein dishevelled homolog DVL-2 phosphorylated form (human)
hDVL2/PhosRes+

organism-modification


PR:000035549 segment polarity protein dishevelled homolog DVL-2 phosphorylated 1 (human)
hDVL2/Phos:1
Yes
organism-modification


PR:000047226 segment polarity protein dishevelled homolog DVL-2 ubiquitinated form (human)
hDVL2/UbiqLys+

organism-modification


PR:000064079 segment polarity protein dishevelled homolog DVL-2 phosphorylated(2+) form (human)
hDVL2/PhosRes(2+)

organism-modification


PR:000074434 segment polarity protein dishevelled homolog DVL-2 cysteinylated 1 (human)
hDVL2/Cyst:1

organism-modification


PR:000083432 segment polarity protein dishevelled homolog DVL-2 methylated 1 (human)
hDVL2/Me:1

organism-gene


PR:Q60838 segment polarity protein dishevelled homolog DVL-2 (mouse)
mDVL2

organism-sequence


PR:Q60838-1 segment polarity protein dishevelled homolog DVL-2 isoform 1 (mouse)
mDVL2/iso:1

sequence


PR:000037983 segment polarity protein dishevelled homolog DVL-2 isoform 1
DVL2/iso:1

organism-sequence


PR:O14641-1 segment polarity protein dishevelled homolog DVL-2 isoform 1 (human)
hDVL2/iso:1

organism-sequence


PR:Q60838-1 segment polarity protein dishevelled homolog DVL-2 isoform 1 (mouse)
mDVL2/iso:1

modification


PR:000019714 segment polarity protein dishevelled homolog DVL-2, initiator methionine removed form
DVL2/InitMet-

modification


PR:000035547 segment polarity protein dishevelled homolog DVL-2 unphosphorylated form
DVL2/PhosRes-

organism-modification


PR:000035550 segment polarity protein dishevelled homolog DVL-2 unphosphorylated form (human)
hDVL2/PhosRes-
Yes
modification


PR:000035548 segment polarity protein dishevelled homolog DVL-2 phosphorylated 1
DVL2/Phos:1

organism-modification


PR:000035549 segment polarity protein dishevelled homolog DVL-2 phosphorylated 1 (human)
hDVL2/Phos:1
Yes
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Functional Annotation (PRO-centric view) Switch to GO Centric View   
PRO Term GO Annotation Evidence
PR:000035549 hDVL2/Phos:1
UniProtKB:O14641, Thr-206, MOD:00047		 acts_upstream_of_or_withinGO:0031577 spindle checkpoint signaling PMID:20823832
increased GO:0051294 establishment of spindle orientation relative to PR:000035550 hDVL2/PhosRes- PMID:20823832
PR:000035550 hDVL2/PhosRes- acts_upstream_of_or_withinGO:0031577 spindle checkpoint signaling PMID:20823832
located_inGO:0000776 kinetochore PMID:20823832
PR:O14641 hDVL2 acts_upstream_of_or_withinGO:0008608 attachment of spindle microtubules to kinetochore PMID:20823832
GO:0031589 cell-substrate adhesion PMID:20823832
GO:0033674 positive regulation of kinase activity PMID:20823832
GO:0034501 protein localization to kinetochore PMID:20823832
GO:0034501 protein localization to kinetochore PMID:20823832
GO:0051310 metaphase chromosome alignment PMID:20823832
enablesGO:0005515 protein binding with PR:P25054 APC PMID:20823832
GO:0005515 protein binding with PR:P33981 hTTK PMID:20823832
GO:0005515 protein binding with PR:P53350 hPLK1 PMID:20823832
located_inGO:0000776 kinetochore PMID:20823832
GO:0000922 spindle pole PMID:20823832
GO:0005819 spindle PMID:20823832
GO:0032154 cleavage furrow PMID:20823832