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Protein Ontology report - eukaryotic translation initiation factor 4E
PR:000006990 - http://purl.obolibrary.org/obo/PR_000006990
 
  Protein Forms  Complex      
Ontology Information Show OBO stanza
  PRO ID
PR:000006990   
  PRO nameeukaryotic translation initiation factor 4E 
  Synonyms
PRO-Short-label: EXACT:EIF4E
Gene-based: RELATED:EIF4EL1 | EIF4F
Other: EXACT:eIF-4E | eIF-4F 25 kDa subunit | eIF4E | mRNA cap-binding protein
  Definition"A protein that is a translation product of the human EIF4E gene or a 1:1 ortholog thereof." [PRO:DNx] 
  PRO Categorygene 
  ParentPR:000000001 protein
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Gene1                                                  Organism-Gene 9                                        
         Sequence1                                                  Organism-Sequence 9                                        
         Modification1                                                  Organism-Modification 3                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Protein Forms Switch to Compact View   

Category  
PRO ID
Name
Short Name
Definition
Ann. Has Annotation?

Comp. In Complex?
gene


PR:000006990
eukaryotic translation initiation factor 4E
EIF4E
"A protein that is a translation product of the human EIF4E gene or a 1:1 ortholog thereof." [PRO:DNx]

organism-gene


PR:O61955
eukaryotic translation initiation factor 4E-3 (worm)
EIF4E (worm)
"A eukaryotic translation initiation factor 4E that is encoded in the genome of worm." [OMA:O61955, PRO:DNx]

organism-sequence


PR:O61955-1
eukaryotic translation initiation factor 4E-3 isoform b (worm)
EIF4E/iso:b (worm)
"A eukaryotic translation initiation factor 4E-3 (worm) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:O61955-1." [PRO:DNx, UniProtKB:O61955]

organism-sequence


PR:O61955-2
eukaryotic translation initiation factor 4E-3 isoform a (worm)
EIF4E/iso:a (worm)
"A eukaryotic translation initiation factor 4E-3 (worm) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:O61955-2." [PRO:DNx, UniProtKB:O61955]

organism-sequence


PR:O61955-3
eukaryotic translation initiation factor 4E-3 isoform c (worm)
EIF4E/iso:c (worm)
"A eukaryotic translation initiation factor 4E-3 (worm) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:O61955-3." [PRO:DNx, UniProtKB:O61955]

organism-gene


PR:P06730
eukaryotic translation initiation factor 4E (human)
hEIF4E
"A eukaryotic translation initiation factor 4E that is encoded in the genome of human." [PRO:DNx, UniProtKB:P06730]

organism-sequence


PR:P06730-1
eukaryotic translation initiation factor 4E isoform 1 (human)
hEIF4E/iso:1
"A eukaryotic translation initiation factor 4E isoform 1 that is encoded in the genome of human." [PRO:DNx]

organism-sequence


PR:P06730-2
eukaryotic translation initiation factor 4E isoform h2 (human)
hEIF4E/iso:h2
"A eukaryotic translation initiation factor 4E (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P06730-2." [PRO:DNx, UniProtKB:P06730]

organism-sequence


PR:P06730-3
eukaryotic translation initiation factor 4E isoform h3 (human)
hEIF4E/iso:h3
"A eukaryotic translation initiation factor 4E (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P06730-3." [PRO:DNx, UniProtKB:P06730]

organism-modification


PR:000028426
eukaryotic translation initiation factor 4E, initiator methionine removed form (human)
hEIF4E/InitMet-
"A eukaryotic translation initiation factor 4E, initiator methionine removed form in human. Example: UniProtKB:P06730-1, 2-217." [PRO:DNx]

Yes
organism-modification


PR:000045646
eukaryotic translation initiation factor 4E phosphorylated 1 (human)
hEIF4E/Phos:1
"A eukaryotic translation initiation factor 4E (human) that has been phosphorylated on the residue at the position equivalent to Ser-53 of the amino acid sequence represented by UniProtKB:P06730-1. Example: UniProtKB:P06730-1, Ser-53, MOD:00046." [iPTMnet:P06730, PMID:3112145]

organism-gene


PR:P07260
eukaryotic translation initiation factor 4E (yeast)
yEIF4E
"A eukaryotic translation initiation factor 4E that is encoded in the genome of yeast." [OMA:P07260, PRO:DNx]

organism-gene


PR:P29338
eukaryotic translation initiation factor 4E (rabbit)
rabbit-EIF4E
"A eukaryotic translation initiation factor 4E that is encoded in the genome of rabbit." [OMA:P29338, PRO:DNx]

organism-gene


PR:P48598
eukaryotic translation initiation factor 4E1 (fruit fly)
fly-EIF4E
"A eukaryotic translation initiation factor 4E that is encoded in the genome of fruit fly." [OMA:P48598, PRO:DNx]

organism-sequence


PR:P48598-1
eukaryotic translation initiation factor 4E1 isoform I (fruit fly)
fly-EIF4E/iso:I
"A eukaryotic translation initiation factor 4E1 (fruit fly) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P48598-1." [PRO:DNx, UniProtKB:P48598]

organism-sequence


PR:P48598-2
eukaryotic translation initiation factor 4E1 isoform II (fruit fly)
fly-EIF4E/iso:II
"A eukaryotic translation initiation factor 4E1 (fruit fly) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P48598-2." [PRO:DNx, UniProtKB:P48598]

organism-gene


PR:P63073
eukaryotic translation initiation factor 4E (mouse)
mEIF4E
"A eukaryotic translation initiation factor 4E that is encoded in the genome of mouse." [OMA:P63073, PRO:DNx]

organism-sequence


PR:P63073-1
eukaryotic translation initiation factor 4E isoform 1 (mouse)
mEIF4E/iso:1
"A eukaryotic translation initiation factor 4E isoform 1 that is encoded in the genome of mouse." [PRO:DNx]

organism-modification


PR:000045850
eukaryotic translation initiation factor 4E phosphorylated 1 (mouse)
mEIF4E/Phos:1
"A eukaryotic translation initiation factor 4E (mouse) that has been phosphorylated at Ser-209. UniProtKB:P63073, Ser-209, MOD:00046." [iPTMnet:P63073, PMID:17689282]

organism-gene


PR:P63074
eukaryotic translation initiation factor 4E (rat)
rEIF4E
"A eukaryotic translation initiation factor 4E that is encoded in the genome of rat." [PRO:DNx]

organism-gene


PR:P78954
eukaryotic translation initiation factor 4E-1 (Schizosaccharomyces pombe 972h-)
Spom972h-EIF4E
"A eukaryotic translation initiation factor 4E that is encoded in the genome of Schizosaccharomyces pombe 972h-." [OMA:P78954, PRO:DNx]

organism-gene


PR:Q55FE0
eukaryotic translation initiation factor 4E (Dictyostelium discoideum)
Dicty-EIF4E
"A eukaryotic translation initiation factor 4E that is encoded in the genome of Dictyostelium discoideum." [OMA:Q55FE0, PRO:DNx]

sequence


PR:000038694
eukaryotic translation initiation factor 4E isoform 1
EIF4E/iso:1
"A eukaryotic translation initiation factor 4E that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P06730-1 or a 1:1 ortholog thereof." [PRO:DNx]

organism-sequence


PR:P06730-1
eukaryotic translation initiation factor 4E isoform 1 (human)
hEIF4E/iso:1
"A eukaryotic translation initiation factor 4E isoform 1 that is encoded in the genome of human." [PRO:DNx]

organism-sequence


PR:P63073-1
eukaryotic translation initiation factor 4E isoform 1 (mouse)
mEIF4E/iso:1
"A eukaryotic translation initiation factor 4E isoform 1 that is encoded in the genome of mouse." [PRO:DNx]

modification


PR:000019768
eukaryotic translation initiation factor 4E, initiator methionine removed form
EIF4E/InitMet-
"A eukaryotic translation initiation factor 4E that has had the initiator methionine removed." [PRO:DNx]

organism-modification


PR:000028426
eukaryotic translation initiation factor 4E, initiator methionine removed form (human)
hEIF4E/InitMet-
"A eukaryotic translation initiation factor 4E, initiator methionine removed form in human. Example: UniProtKB:P06730-1, 2-217." [PRO:DNx]

Yes
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EIF4E forms found in complexes   

EIF4E Component
 Complexes
PR:000028426 hEIF4E/InitMet- PR:000028454 eIF4E:4E-BP (human)