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Protein Ontology report - chymotrypsin-like elastase family member 2A
PR:000007010 - http://purl.obolibrary.org/obo/PR_000007010
 
  Protein Forms  Annotations      
Ontology Information Show OBO stanza
  PRO ID
PR:000007010   
  PRO namechymotrypsin-like elastase family member 2A 
  Synonyms
PRO-Short-label: EXACT:CELA2A
Gene-based: RELATED:Ela-2 | Ela2 | ELA2A
Other: EXACT:elastase-2A
  Definition"A trypsin that is a translation product of the human CELA2A gene or a 1:1 ortholog thereof." [PRO:DNx] 
  PRO Categorygene 
  ParentPR:000027795 trypsin
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Gene1                                                  Organism-Gene 4                                        
         Sequence1                                                  Organism-Sequence 2                                        
         Modification3                                                  Organism-Modification 4                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Protein Forms Switch to Compact View   

Category  

PRO ID

Name

Short Name

Definition

Ann. Has Annotation?

Comp. In Complex?
gene



PR:000007010

chymotrypsin-like elastase family member 2A

CELA2A


"A trypsin that is a translation product of the human CELA2A gene or a 1:1 ortholog thereof." [PRO:DNx]


organism-gene



PR:P00774

chymotrypsin-like elastase family member 2A (rat)

rCELA2A


"A chymotrypsin-like elastase family member 2A that is encoded in the genome of rat." [OMA:P00774, PRO:DNx]


organism-sequence



PR:P00774-1

chymotrypsin-like elastase family member 2A isoform 1 (rat)

rCELA2A/iso:1


"A chymotrypsin-like elastase family member 2A isoform 1 that is encoded in the genome of rat." [PRO:DNx]


organism-gene



PR:P05208

chymotrypsin-like elastase family member 2A (mouse)

mCELA2A


"A chymotrypsin-like elastase family member 2A that is encoded in the genome of mouse." [PRO:DNx]


organism-sequence



PR:P05208-1

chymotrypsin-like elastase family member 2A isoform 1 (mouse)

mCELA2A/iso:1


"A chymotrypsin-like elastase family member 2A isoform 1 that is encoded in the genome of mouse." [PRO:DNx]


organism-modification



PR:000037243

chymotrypsin-like elastase family member 2A, precursor (mouse)

mCELA2A/pre-pro


"A chymotrypsin-like elastase family member 2A, full-length form in mouse." [PMID:3641189, PRO:KRC]


organism-modification



PR:000037244

chymotrypsin-like elastase family member 2A, pro-form (mouse)

mCELA2A/pro


"A chymotrypsin-like elastase family member 2A, signal peptide removed form in mouse. UniProtKB:P05208, 17-271." [PMID:20179351, PRO:KRC]


organism-modification



PR:000037245

chymotrypsin-like elastase family member 2A, mature form (mouse)

mCELA2A/mature


"A chymotrypsin-like elastase family member 2A, pro-form (mouse) that has had the activation peptide removed by proteolytic cleavage. UniProtKB:P05208, 31-271." [PMID:20179351, PMID:3641189, PRO:KRC]

Yes

organism-gene



PR:P08217

chymotrypsin-like elastase family member 2A (human)

hCELA2A


"A chymotrypsin-like elastase family member 2A that is encoded in the genome of human." [PRO:DNx, UniProtKB:P08217]


organism-modification



PR:000071040

chymotrypsin-like elastase family member 2A, mature form (human)

hCELA2A/mature


"A chymotrypsin-like elastase family member 2A (human) that has had the signal peptide and propeptide removed. UniProtKB:P08217, 29-269." [PRO:DNx, Reactome:R-HSA-8849616, Reactome:R-HSA-8934818]


organism-gene



PR:P08419

chymotrypsin-like elastase family member 2A (pig)

pig-CELA2A


"A chymotrypsin-like elastase family member 2A that is encoded in the genome of pig." [OMA:P08419, PRO:DNx]


sequence



PR:000038672

chymotrypsin-like elastase family member 2A isoform 1

CELA2A/iso:1


"A chymotrypsin-like elastase family member 2A that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P05208-1 or a 1:1 ortholog thereof." [PRO:DNx]


organism-sequence



PR:P00774-1

chymotrypsin-like elastase family member 2A isoform 1 (rat)

rCELA2A/iso:1


"A chymotrypsin-like elastase family member 2A isoform 1 that is encoded in the genome of rat." [PRO:DNx]


organism-sequence



PR:P05208-1

chymotrypsin-like elastase family member 2A isoform 1 (mouse)

mCELA2A/iso:1


"A chymotrypsin-like elastase family member 2A isoform 1 that is encoded in the genome of mouse." [PRO:DNx]


modification



PR:000019774

chymotrypsin-like elastase family member 2A, full-length form

ELA2A/Full


"A chymotrypsin-like elastase family member 2A that contains all the amino acids specified by its template mRNA." [PRO:DNx]


organism-modification



PR:000037243

chymotrypsin-like elastase family member 2A, precursor (mouse)

mCELA2A/pre-pro


"A chymotrypsin-like elastase family member 2A, full-length form in mouse." [PMID:3641189, PRO:KRC]


modification



PR:000019775

chymotrypsin-like elastase family member 2A, signal peptide removed form

ELA2A/SigPep-


"A chymotrypsin-like elastase family member 2A that has had the signal peptide removed." [PRO:DNx]


organism-modification



PR:000037244

chymotrypsin-like elastase family member 2A, pro-form (mouse)

mCELA2A/pro


"A chymotrypsin-like elastase family member 2A, signal peptide removed form in mouse. UniProtKB:P05208, 17-271." [PMID:20179351, PRO:KRC]


organism-modification



PR:000037245

chymotrypsin-like elastase family member 2A, mature form (mouse)

mCELA2A/mature


"A chymotrypsin-like elastase family member 2A, pro-form (mouse) that has had the activation peptide removed by proteolytic cleavage. UniProtKB:P05208, 31-271." [PMID:20179351, PMID:3641189, PRO:KRC]

Yes

organism-modification



PR:000071040

chymotrypsin-like elastase family member 2A, mature form (human)

hCELA2A/mature


"A chymotrypsin-like elastase family member 2A (human) that has had the signal peptide and propeptide removed. UniProtKB:P08217, 29-269." [PRO:DNx, Reactome:R-HSA-8849616, Reactome:R-HSA-8934818]


modification



PR:000019776

chymotrypsin-like elastase family member 2A proteolytic cleavage product

ELA2A/ClvPrd


"A chymotrypsin-like elastase family member 2A that has been processed by proteolytic cleavage." [PRO:DNx]


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Functional Annotation (PRO-centric view) Switch to GO Centric View   
PRO Term GO Annotation Evidence
PR:000037245 mCELA2A/mature
UniProtKB:P05208, 31-271
acts_upstream_of_or_withinGO:0006508 proteolysis MGI_ref:4440399; PMID:20179351
GO:0061436 establishment of skin barrier MGI_ref:4440399; PMID:20179351
enablesGO:0017171 serine hydrolase activity MGI_ref:4440399; PMID:20179351
GO:0017171 serine hydrolase activity MGI_ref:4440399; PMID:20179351