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Protein Ontology report - coagulation factor XII
PR:000007296 - http://purl.obolibrary.org/obo/PR_000007296
 
  Protein Forms      
Ontology Information Show OBO stanza
  PRO ID
PR:000007296   
  PRO namecoagulation factor XII 
  Synonyms
PRO-Short-label: EXACT:F12
Other: EXACT:HAF | hageman factor
  Definition"A protein that is a translation product of the human F12 gene or a 1:1 ortholog thereof." [PRO:DNx] 
  PRO Categorygene 
  ParentPR:000000001 protein
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Gene1                                                  Organism-Gene 3                                        
         Sequence0                                                  Organism-Sequence 0                                        
         Modification2                                                  Organism-Modification 15                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Related Cross References

  Db identifiers
IUPHARobj:2361
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Protein Forms Switch to Compact View   

Category  
PRO ID
Name
Short Name
Definition
Ann. Has Annotation?

Comp. In Complex?
gene


PR:000007296
coagulation factor XII
F12
"A protein that is a translation product of the human F12 gene or a 1:1 ortholog thereof." [PRO:DNx]

organism-gene


PR:D3ZTE0
coagulation factor XII (rat)
rF12
"A coagulation factor XII that is encoded in the genome of rat." [OMA:D3ZTE0, PRO:DNx]

organism-gene


PR:P00748
coagulation factor XII (human)
hF12
"A coagulation factor XII that is encoded in the genome of human." [PRO:DNx, UniProtKB:P00748]

organism-modification


PR:000047348
coagulation factor XII, signal peptide removed form (human)
hF12/SigPep-
"A coagulation factor XII (human) that has had the signal peptide removed. UniProtKB:P00748, 20-615." [PRO:DNx, Reactome:R-HSA-158214]

organism-modification


PR:000063138
coagulation factor XII sequence variant T328R, signal peptide removed form (human)
hF12/var:T328R/SigPep-
"A coagulation factor XII (human) that has an Arg residue at the position equivalent to Thr-328 of the amino acid sequence represented by UniProtKB:P00748 and that has had the signal peptide removed. UniProtKB:P00748, 20-615, Thr-328, CHEBI:29952." [PRO:DNx, Reactome:R-HSA-9653226]

organism-modification


PR:000063490
coagulation factor XII sequence variant T328K, signal peptide removed form (human)
hF12/var:T328K/SigPep-
"A coagulation factor XII (human) that has a Lys residue at the position equivalent to Thr-328 of the amino acid sequence represented by UniProtKB:P00748 and that has had the signal peptide removed. UniProtKB:P00748, 20-615, Thr-328, CHEBI:29967." [PRO:DNx, Reactome:R-HSA-9653238]

organism-modification


PR:000051237
coagulation factor XII O-glycosylated 1 (human)
hF12/OGlyco:1
"A coagulation factor XII (human) that has been O-glycosylated at the residue equivalent to Ser-335 of the amino acid sequence represented by UniProtKB:P00748-1, in which the glycan composition is represented by GlyTouCan:G29068FM. Example: UniProtKB:P00748-1, Ser-335, MOD:00002~GNO:G29068FM." [GlyGen:P00748-1, PMID:30459171, PRO:DNx]

organism-modification


PR:000051238
coagulation factor XII O-glycosylated 2 (human)
hF12/OGlyco:2
"A coagulation factor XII (human) that has been O-glycosylated at the residue equivalent to Ser-335 of the amino acid sequence represented by UniProtKB:P00748-1, in which the glycan composition is represented by GlyTouCan:G43417UB. Example: UniProtKB:P00748-1, Ser-335, MOD:00002~GNO:G43417UB." [GlyGen:P00748-1, PMID:30459171, PRO:DNx]

organism-modification


PR:000051239
coagulation factor XII O-glycosylated 3 (human)
hF12/OGlyco:3
"A coagulation factor XII (human) that has been O-glycosylated at the residue equivalent to Thr-299 of the amino acid sequence represented by UniProtKB:P00748-1, in which the glycan composition is represented by GlyTouCan:G29068FM. Example: UniProtKB:P00748-1, Thr-299, MOD:00005~GNO:G29068FM." [GlyGen:P00748-1, PMID:30459171, PRO:DNx]

organism-modification


PR:000051240
coagulation factor XII O-glycosylated 4 (human)
hF12/OGlyco:4
"A coagulation factor XII (human) that has been O-glycosylated at the residue equivalent to Thr-299 of the amino acid sequence represented by UniProtKB:P00748-1, in which the glycan composition is represented by GlyTouCan:G53434XO. Example: UniProtKB:P00748-1, Thr-299, MOD:00005~GNO:G53434XO." [GlyGen:P00748-1, PMID:30459171, PRO:DNx]

organism-modification


PR:000051241
coagulation factor XII O-glycosylated 5 (human)
hF12/OGlyco:5
"A coagulation factor XII (human) that has been O-glycosylated at the residue equivalent to Thr-299 of the amino acid sequence represented by UniProtKB:P00748-1, in which the glycan composition is represented by GlyTouCan:G58001LT. Example: UniProtKB:P00748-1, Thr-299, MOD:00005~GNO:G58001LT." [GlyGen:P00748-1, PMID:30459171, PRO:DNx]

organism-modification


PR:000051242
coagulation factor XII O-glycosylated 6 (human)
hF12/OGlyco:6
"A coagulation factor XII (human) that has been O-glycosylated at the residue equivalent to Thr-328 of the amino acid sequence represented by UniProtKB:P00748-1, in which the glycan composition is represented by GlyTouCan:G29068FM. Example: UniProtKB:P00748-1, Thr-328, MOD:00005~GNO:G29068FM." [GlyGen:P00748-1, PMID:30459171, PRO:DNx]

organism-modification


PR:000051243
coagulation factor XII O-glycosylated 7 (human)
hF12/OGlyco:7
"A coagulation factor XII (human) that has been O-glycosylated at the residue equivalent to Thr-328 of the amino acid sequence represented by UniProtKB:P00748-1, in which the glycan composition is represented by GlyTouCan:G53434XO. Example: UniProtKB:P00748-1, Thr-328, MOD:00005~GNO:G53434XO." [GlyGen:P00748-1, PMID:30459171, PRO:DNx]

organism-modification


PR:000051244
coagulation factor XII O-glycosylated 8 (human)
hF12/OGlyco:8
"A coagulation factor XII (human) that has been O-glycosylated at the residue equivalent to Thr-328 of the amino acid sequence represented by UniProtKB:P00748-1, in which the glycan composition is represented by GlyTouCan:G58001LT. Example: UniProtKB:P00748-1, Thr-328, MOD:00005~GNO:G58001LT." [GlyGen:P00748-1, PMID:30459171, PRO:DNx]

organism-modification


PR:000051245
coagulation factor XII O-glycosylated 9 (human)
hF12/OGlyco:9
"A coagulation factor XII (human) that has been O-glycosylated at the residue equivalent to Thr-337 of the amino acid sequence represented by UniProtKB:P00748-1, in which the glycan composition is represented by GlyTouCan:G29068FM. Example: UniProtKB:P00748-1, Thr-337, MOD:00005~GNO:G29068FM." [GlyGen:P00748-1, PMID:30459171, PRO:DNx]

organism-modification


PR:000051246
coagulation factor XII O-glycosylated 10 (human)
hF12/OGlyco:10
"A coagulation factor XII (human) that has been O-glycosylated at the residue equivalent to Thr-337 of the amino acid sequence represented by UniProtKB:P00748-1, in which the glycan composition is represented by GlyTouCan:G43417UB. Example: UniProtKB:P00748-1, Thr-337, MOD:00005~GNO:G43417UB." [GlyGen:P00748-1, PMID:30459171, PRO:DNx]

organism-modification


PR:000051247
coagulation factor XII O-glycosylated 11 (human)
hF12/OGlyco:11
"A coagulation factor XII (human) that has been O-glycosylated at the residue equivalent to Thr-43 of the amino acid sequence represented by UniProtKB:P00748-1, in which the glycan composition is represented by GlyTouCan:G43417UB. Example: UniProtKB:P00748-1, Thr-43, MOD:00005~GNO:G43417UB." [GlyGen:P00748-1, PMID:30459171, PRO:DNx]

organism-modification


PR:000070295
coagulation factor XII methylated 1 (human)
hF12/Me:1
"A coagulation factor XII (human) that has been methylated on the residue at the position equivalent to Cys-486 of the amino acid sequence represented by UniProtKB:P00748. UniProtKB:P00748, Cys-486, MOD:00660." [IEDB_epitope:1051027, PRO:DNx]

organism-gene


PR:Q80YC5
coagulation factor XII (mouse)
mF12
"A coagulation factor XII that is encoded in the genome of mouse." [OMA:Q80YC5, PRO:DNx]

modification


PR:000019828
coagulation factor XII, signal peptide removed form
F12/SigPep-
"A coagulation factor XII that has had the signal peptide removed." [PRO:DNx]

organism-modification


PR:000047348
coagulation factor XII, signal peptide removed form (human)
hF12/SigPep-
"A coagulation factor XII (human) that has had the signal peptide removed. UniProtKB:P00748, 20-615." [PRO:DNx, Reactome:R-HSA-158214]

organism-modification


PR:000063138
coagulation factor XII sequence variant T328R, signal peptide removed form (human)
hF12/var:T328R/SigPep-
"A coagulation factor XII (human) that has an Arg residue at the position equivalent to Thr-328 of the amino acid sequence represented by UniProtKB:P00748 and that has had the signal peptide removed. UniProtKB:P00748, 20-615, Thr-328, CHEBI:29952." [PRO:DNx, Reactome:R-HSA-9653226]

organism-modification


PR:000063490
coagulation factor XII sequence variant T328K, signal peptide removed form (human)
hF12/var:T328K/SigPep-
"A coagulation factor XII (human) that has a Lys residue at the position equivalent to Thr-328 of the amino acid sequence represented by UniProtKB:P00748 and that has had the signal peptide removed. UniProtKB:P00748, 20-615, Thr-328, CHEBI:29967." [PRO:DNx, Reactome:R-HSA-9653238]

modification


PR:000019829
coagulation factor XII proteolytic cleavage product
F12/ClvPrd
"A coagulation factor XII that has been processed by proteolytic cleavage." [PRO:DNx]