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Protein Ontology report - vascular endothelial growth factor receptor 1
PR:000007563 - http://purl.obolibrary.org/obo/PR_000007563
 
  Protein Forms  Annotations      
Ontology Information Show OBO stanza
  PRO ID
PR:000007563   
  PRO namevascular endothelial growth factor receptor 1 
  Synonyms
PRO-Short-label: EXACT:FLT1
Gene-based: RELATED:Emrk2 | FLT | FRT | VEGFR1
Other: EXACT:embryonic receptor kinase 2 | FLT-1 | Fms-like tyrosine kinase 1 | tyrosine-protein kinase FRT | tyrosine-protein kinase receptor FLT | vascular permeability factor receptor | VEGFR-1
  Definition"A vascular endothelial growth factor receptor that is a translation product of the human FLT1 gene or a 1:1 ortholog thereof." [PRO:DNx] 
  PRO Categorygene 
  ParentPR:000001971 vascular endothelial growth factor receptor
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Gene1                                                  Organism-Gene 5                                        
         Sequence2                                                  Organism-Sequence 12                                        
         Modification2                                                  Organism-Modification 6                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Related Cross References

  Db identifiers
IUPHARobj:1812
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Protein Forms Switch to Compact View   

Category  

PRO ID

Name

Short Name

Definition

Ann. Has Annotation?

Comp. In Complex?
gene



PR:000007563

vascular endothelial growth factor receptor 1

FLT1


"A vascular endothelial growth factor receptor that is a translation product of the human FLT1 gene or a 1:1 ortholog thereof." [PRO:DNx]


organism-gene



PR:P17948

vascular endothelial growth factor receptor 1 (human)

hFLT1


"A vascular endothelial growth factor receptor 1 that is encoded in the genome of human." [PRO:CNA]


organism-sequence



PR:P17948-1

vascular endothelial growth factor receptor 1 isoform 1 (human)

hFLT1/iso:1


"A vascular endothelial growth factor receptor 1 isoform 1 that is encoded in the genome of human." [PMID:2110562, PRO:CNA]


organism-sequence



PR:P17948-2

vascular endothelial growth factor receptor 1 isoform 2 (human)

hFLT1/iso:2


"A vascular endothelial growth factor receptor 1 isoform 2 that is encoded in the genome of human." [PMID:8248162, PRO:CNA]


organism-sequence



PR:P17948-3

vascular endothelial growth factor receptor 1 isoform h3 (human)

hFLT1/iso:h3


"A vascular endothelial growth factor receptor 1 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P17948-3." [PRO:DNx, UniProtKB:P17948]


organism-sequence



PR:P17948-4

vascular endothelial growth factor receptor 1 isoform h4 (human)

hFLT1/iso:h4


"A vascular endothelial growth factor receptor 1 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P17948-4." [PRO:DNx, UniProtKB:P17948]


organism-sequence



PR:P17948-5

vascular endothelial growth factor receptor 1 isoform h5 (human)

hFLT1/iso:h5


"A vascular endothelial growth factor receptor 1 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P17948-5." [PRO:DNx, UniProtKB:P17948]


organism-sequence



PR:P17948-6

vascular endothelial growth factor receptor 1 isoform h6 (human)

hFLT1/iso:h6


"A vascular endothelial growth factor receptor 1 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P17948-6." [PRO:DNx, UniProtKB:P17948]


organism-sequence



PR:P17948-7

vascular endothelial growth factor receptor 1 isoform h7 (human)

hFLT1/iso:h7


"A vascular endothelial growth factor receptor 1 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P17948-7." [PRO:DNx, UniProtKB:P17948]


organism-sequence



PR:P17948-8

vascular endothelial growth factor receptor 1 isoform h8 (human)

hFLT1/iso:h8


"A vascular endothelial growth factor receptor 1 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P17948-8." [PRO:DNx, UniProtKB:P17948]


organism-modification



PR:000047429

vascular endothelial growth factor receptor 1, signal peptide removed form (human)

hFLT1/SigPep-


"A vascular endothelial growth factor receptor 1 (human) that has had the signal peptide removed. UniProtKB:P17948, 27-1338." [PRO:DNx, Reactome:R-HSA-3004464]


organism-modification



PR:000055957

vascular endothelial growth factor receptor 1 N-glycosylated 1 (human)

hFLT1/NGlyco:1


"A vascular endothelial growth factor receptor 1 (human) that has been N-glycosylated at the residue equivalent to Asn-196 of the amino acid sequence represented by UniProtKB:P17948-1, in which the glycan composition is represented by GlyTouCan:G28681TP. Example: UniProtKB:P17948-1, Asn-196, MOD:00160~GNO:G28681TP." [GlyGen:P17948-1, PMID:23345538, PRO:DNx]


organism-modification



PR:000055958

vascular endothelial growth factor receptor 1 N-glycosylated 2 (human)

hFLT1/NGlyco:2


"A vascular endothelial growth factor receptor 1 (human) that has been N-glycosylated at the residue equivalent to Asn-323 of the amino acid sequence represented by UniProtKB:P17948-1, in which the glycan composition is represented by GlyTouCan:G28681TP. Example: UniProtKB:P17948-1, Asn-323, MOD:00160~GNO:G28681TP." [GlyGen:P17948-1, PMID:23345538, PRO:DNx]


organism-modification



PR:000055959

vascular endothelial growth factor receptor 1 N-glycosylated 3 (human)

hFLT1/NGlyco:3


"A vascular endothelial growth factor receptor 1 (human) that has been N-glycosylated at the residue equivalent to Asn-474 of the amino acid sequence represented by UniProtKB:P17948-1, in which the glycan composition is represented by GlyTouCan:G39446WN. Example: UniProtKB:P17948-1, Asn-474, MOD:00160~GNO:G39446WN." [GlyGen:P17948-1, PMID:23345538, PRO:DNx]


organism-modification



PR:000055960

vascular endothelial growth factor receptor 1 N-glycosylated 4 (human)

hFLT1/NGlyco:4


"A vascular endothelial growth factor receptor 1 (human) that has been N-glycosylated at the residue equivalent to Asn-625 of the amino acid sequence represented by UniProtKB:P17948-1, in which the glycan composition is represented by GlyTouCan:G57776ZU. Example: UniProtKB:P17948-1, Asn-625, MOD:00160~GNO:G57776ZU." [GlyGen:P17948-1, PMID:23345538, PRO:DNx]


organism-modification



PR:000072589

vascular endothelial growth factor receptor 1 deaminated 1 (human)

hFLT1/Deam:1


"A vascular endothelial growth factor receptor 1 (human) that has been deaminated on the residue at the position equivalent to Asn-100 of the amino acid sequence represented by UniProtKB:P17948-1. Example: UniProtKB:P17948-1, Asn-100, MOD:00684." [IEDB_epitope:929455, PRO:DNx]


organism-gene



PR:P35969

vascular endothelial growth factor receptor 1 (mouse)

mFLT1


"A vascular endothelial growth factor receptor 1 that is encoded in the genome of mouse." [MGI:95558, OMA:P35969, PRO:HJD]

Yes

organism-sequence



PR:O55095

vascular endothelial growth factor receptor 1 isoform 2 (mouse)

mFLT1/iso:2


"A vascular endothelial growth factor receptor 1 isoform 2 that is encoded in the genome of mouse." [EMBL:D88690, PMID:1498287, PMID:8248162, PMID:8393164, PMID:9524283, PRO:HJD]

Yes

organism-sequence



PR:P35969-1

vascular endothelial growth factor receptor 1 isoform 1 (mouse)

mFLT1/iso:1


"A vascular endothelial growth factor receptor 1 isoform 1 that is encoded in the genome of mouse." [PMID:14982871, PRO:HJD]

Yes

organism-gene



PR:P53767

vascular endothelial growth factor receptor 1 (rat)

rFLT1


"A vascular endothelial growth factor receptor 1 that is encoded in the genome of rat." [OMA:P53767, PRO:DNx]


organism-gene



PR:Q21038

tyrosine-protein kinase receptor ver-3 (worm)

FLT1 (worm)


"A vascular endothelial growth factor receptor 1 that is encoded in the genome of worm." [OMA:Q21038, PRO:DNx]


organism-gene



PR:Q8QHL3

vascular endothelial growth factor receptor 1 (chicken)

chick-FLT1


"A vascular endothelial growth factor receptor 1 that is encoded in the genome of chicken." [PRO:DNx]


organism-sequence



PR:Q8QHL3-1

vascular endothelial growth factor receptor 1 isoform 1 (chicken)

chick-FLT1/iso:1


"A vascular endothelial growth factor receptor 1 (chicken) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q8QHL3-1." [PRO:DNx, UniProtKB:Q8QHL3]


organism-sequence



PR:Q8QHL3-2

vascular endothelial growth factor receptor 1 isoform 2 (chicken)

chick-FLT1/iso:2


"A vascular endothelial growth factor receptor 1 (chicken) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q8QHL3-2." [PRO:DNx, UniProtKB:Q8QHL3]


sequence



PR:000025514

vascular endothelial growth factor receptor 1 isoform 1

FLT1/iso:1


"A vascular endothelial growth factor receptor 1 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P17948-1 or a 1:1 ortholog thereof." [PMID:2158038, PRO:CNA]


organism-sequence



PR:P17948-1

vascular endothelial growth factor receptor 1 isoform 1 (human)

hFLT1/iso:1


"A vascular endothelial growth factor receptor 1 isoform 1 that is encoded in the genome of human." [PMID:2110562, PRO:CNA]


organism-sequence



PR:P35969-1

vascular endothelial growth factor receptor 1 isoform 1 (mouse)

mFLT1/iso:1


"A vascular endothelial growth factor receptor 1 isoform 1 that is encoded in the genome of mouse." [PMID:14982871, PRO:HJD]

Yes

modification



PR:000026707

vascular endothelial growth factor receptor 1 isoform 1, signal peptide removed form

FLT1/iso:1/SigPep-


"A vascular endothelial growth factor receptor 1 isoform 1 that has had the signal peptide removed." [PRO:DNx]


sequence



PR:000025515

vascular endothelial growth factor receptor 1 isoform 2

FLT1/iso:2


"A vascular endothelial growth factor receptor 1 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P17948-2 or a 1:1 ortholog thereof." [PMID:8248162, PRO:CNA]


organism-sequence



PR:O55095

vascular endothelial growth factor receptor 1 isoform 2 (mouse)

mFLT1/iso:2


"A vascular endothelial growth factor receptor 1 isoform 2 that is encoded in the genome of mouse." [EMBL:D88690, PMID:1498287, PMID:8248162, PMID:8393164, PMID:9524283, PRO:HJD]

Yes

organism-sequence



PR:P17948-2

vascular endothelial growth factor receptor 1 isoform 2 (human)

hFLT1/iso:2


"A vascular endothelial growth factor receptor 1 isoform 2 that is encoded in the genome of human." [PMID:8248162, PRO:CNA]


modification



PR:000019913

vascular endothelial growth factor receptor 1, signal peptide removed form

FLT1/SigPep-


"A vascular endothelial growth factor receptor 1 that has had the signal peptide removed." [PRO:DNx]


modification



PR:000026707

vascular endothelial growth factor receptor 1 isoform 1, signal peptide removed form

FLT1/iso:1/SigPep-


"A vascular endothelial growth factor receptor 1 isoform 1 that has had the signal peptide removed." [PRO:DNx]


organism-modification



PR:000047429

vascular endothelial growth factor receptor 1, signal peptide removed form (human)

hFLT1/SigPep-


"A vascular endothelial growth factor receptor 1 (human) that has had the signal peptide removed. UniProtKB:P17948, 27-1338." [PRO:DNx, Reactome:R-HSA-3004464]


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Functional Annotation (PRO-centric view) Switch to GO Centric View   
PRO Term GO Annotation Evidence
PR:O55095 mFLT1/iso:2 acts_upstream_of_or_withinGO:0002040 sprouting angiogenesis PMID:19758562
PR:P35969 mFLT1 acts_upstream_of_or_withinGO:0001569 branching involved in blood vessel morphogenesis PMID:14982871
GO:0002040 sprouting angiogenesis PMID:19758562
GO:0048010 vascular endothelial growth factor receptor signaling pathway PMID:9689083
PR:P35969-1 mFLT1/iso:1 acts_upstream_of_or_withinNOT GO:0002040 sprouting angiogenesis PMID:19758562