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Protein Ontology report - fms-related tyrosine kinase 3 ligand
PR:000007564 - http://purl.obolibrary.org/obo/PR_000007564
 
  Protein Forms  Annotations      
Ontology Information Show OBO stanza
  PRO ID
PR:000007564   
  PRO namefms-related tyrosine kinase 3 ligand 
  Synonyms
PRO-Short-label: EXACT:FLT3LG
Other: EXACT:flt3 ligand | Flt3L | SL cytokine
  Definition"A protein that is a translation product of the human FLT3LG gene or a 1:1 ortholog thereof." [PRO:DNx] 
  PRO Categorygene 
  ParentPR:000000001 protein
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Gene1                                                  Organism-Gene 2                                        
         Sequence0                                                  Organism-Sequence 7                                        
         Modification0                                                  Organism-Modification 2                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Protein Forms Switch to Compact View   

Category  

PRO ID

Name

Short Name

Definition

Ann. Has Annotation?

Comp. In Complex?
gene



PR:000007564

fms-related tyrosine kinase 3 ligand

FLT3LG


"A protein that is a translation product of the human FLT3LG gene or a 1:1 ortholog thereof." [PRO:DNx]


organism-gene



PR:P49771

fms-related tyrosine kinase 3 ligand (human)

hFLT3LG


"An fms-related tyrosine kinase 3 ligand that is encoded in the genome of human." [PRO:DNx, UniProtKB:P49771]


organism-sequence



PR:P49771-1

fms-related tyrosine kinase 3 ligand isoform h1 (human)

hFLT3LG/iso:h1


"An fms-related tyrosine kinase 3 ligand (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P49771-1." [PRO:DNx, UniProtKB:P49771]


organism-sequence



PR:P49771-2

fms-related tyrosine kinase 3 ligand isoform h2 (human)

hFLT3LG/iso:h2


"An fms-related tyrosine kinase 3 ligand (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P49771-2." [PRO:DNx, UniProtKB:P49771]


organism-sequence



PR:P49771-3

fms-related tyrosine kinase 3 ligand isoform h3 (human)

hFLT3LG/iso:h3


"An fms-related tyrosine kinase 3 ligand (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P49771-3." [PRO:DNx, UniProtKB:P49771]


organism-modification



PR:000047431

fms-related tyrosine kinase 3 ligand, signal peptide removed form (human)

hFLT3LG/SigPep-


"An fms-related tyrosine kinase 3 ligand (human) that has had the signal peptide removed. UniProtKB:P49771, 27-235." [PRO:DNx, Reactome:R-HSA-6786793]


organism-modification



PR:000074183

fms-related tyrosine kinase 3 ligand cysteinylated 1 (human)

hFLT3LG/Cyst:1


"An fms-related tyrosine kinase 3 ligand (human) that has been cysteinylated on the residue at the position equivalent to Cys-111 of the amino acid sequence represented by UniProtKB:P49771-1. Example: UniProtKB:P49771-1, Cys-111, MOD:00765." [IEDB_epitope:2129923, PRO:DNx]


organism-gene



PR:P49772

fms-related tyrosine kinase 3 ligand (mouse)

mFLT3LG


"An fms-related tyrosine kinase 3 ligand that is encoded in the genome of mouse." [OMA:P49772, PRO:DNx]


organism-sequence



PR:P49772-1

fms-related tyrosine kinase 3 ligand isoform 1 (mouse)

mFLT3LG/iso:1


"An fms-related tyrosine kinase 3 ligand (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P49772-1." [PMID:16141072, PRO:HJD]

Yes

organism-sequence



PR:P49772-2

fms-related tyrosine kinase 3 ligand isoform 2 (mouse)

mFLT3LG/iso:2


"An fms-related tyrosine kinase 3 ligand (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P49772-2." [PMID:16141072, PRO:HJD]

Yes

organism-sequence



PR:P49772-3

fms-related tyrosine kinase 3 ligand isoform 3 (mouse)

mFLT3LG/iso:3


"An fms-related tyrosine kinase 3 ligand (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P49772-3." [PMID:16141072, PRO:HJD]

Yes

organism-sequence



PR:P49772-4

fms-related tyrosine kinase 3 ligand isoform 4 (mouse)

mFLT3LG/iso:4


"An fms-related tyrosine kinase 3 ligand (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P49772-4." [PMID:16141072, PRO:HJD]


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Functional Annotation (PRO-centric view) Switch to GO Centric View   
PRO Term GO Annotation Evidence
PR:P49772-1 mFLT3LG/iso:1 enablesGO:0030971 receptor tyrosine kinase binding with PR:Q00342 CD135 (mouse) MGI_ref:83693; PMID:8896402
located_inGO:0009897 external side of plasma membrane MGI_ref:83693; PMID:8896402
PR:P49772-2 mFLT3LG/iso:2 enablesGO:0030971 receptor tyrosine kinase binding with PR:Q00342 CD135 (mouse) MGI_ref:83693; PMID:8896402
located_inGO:0009897 external side of plasma membrane MGI_ref:83693; PMID:8896402
PR:P49772-3 mFLT3LG/iso:3 enablesGO:0030971 receptor tyrosine kinase binding with PR:Q00342 CD135 (mouse) MGI_ref:83693; PMID:8896402
GO:0042803 protein homodimerization activity MGI_ref:83693; PMID:8896402
located_inGO:0005615 extracellular space MGI_ref:83693; PMID:8896402