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Protein Ontology report - erythroid transcription factor
PR:000007857 - http://purl.obolibrary.org/obo/PR_000007857
 
  Protein Forms  Annotations      
Ontology Information Show OBO stanza
  PRO ID
PR:000007857   
  PRO nameerythroid transcription factor 
  Synonyms
PRO-Short-label: EXACT:GATA1
Gene-based: RELATED:ERYF1 | GF1
Other: EXACT:Eryf1 | GATA-1 | GATA-binding factor 1 | NF-E1 DNA-binding protein
RELATED:GF-1
  Definition"A protein that is a translation product of the human GATA1 gene or a 1:1 ortholog thereof." [PRO:DNx] 
  CommentRequested by=CL. 
  PRO Categorygene 
  ParentPR:000000001 protein
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Gene1                                                  Organism-Gene 4                                        
         Sequence2                                                  Organism-Sequence 5                                        
         Modification3                                                  Organism-Modification 6                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Protein Forms Switch to Compact View   

Category  
PRO ID
Name
Short Name
Definition
Ann. Has Annotation?

Comp. In Complex?
gene


PR:000007857
erythroid transcription factor
GATA1
"A protein that is a translation product of the human GATA1 gene or a 1:1 ortholog thereof." [PRO:DNx]

organism-gene


PR:P15976
erythroid transcription factor (human)
hGATA1
"An erythroid transcription factor that is encoded in the genome of human." [PRO:DNx, UniProtKB:P15976]

organism-sequence


PR:P15976-1
erythroid transcription factor isoform 1 (human)
hGATA1/iso:1
"An erythroid transcription factor isoform 1 that is encoded in the genome of human." [PRO:HJD]

organism-modification


PR:000027073
erythroid transcription factor isoform 1 phosphorylated and sumoylated 1 (human)
hGATA1/iso:1/PhosSumo:1
"An erythroid transcription factor isoform 1 phosphorylated and sumoylated 1 in human. UniProtKB:P15976-1, Lys-137, MOD:01149|Ser-142, MOD:00046." [PMID:16371476, PRO:CNA]

organism-sequence


PR:P15976-2
erythroid transcription factor isoform h2 (human)
hGATA1/iso:h2
"An erythroid transcription factor (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P15976-2." [PRO:DNx, UniProtKB:P15976]

organism-sequence


PR:P15976-3
erythroid transcription factor isoform 2 (human)
hGATA1/iso:2
"An erythroid transcription factor isoform 2 that is encoded in the genome of human. This isoform is produced by alternative initiation." [PMID:8524811, PRO:CNA]

organism-modification


PR:000068620
erythroid transcription factor cysteinylated 1 (human)
hGATA1/Cyst:1
"An erythroid transcription factor (human) that has been cysteinylated on the residue at the position equivalent to Cys-282 of the amino acid sequence represented by UniProtKB:P15976-1. Example: UniProtKB:P15976-1, Cys-282, MOD:00765." [IEDB_epitope:2116600, PRO:DNx]

organism-modification


PR:000071218
erythroid transcription factor methylated 1 (human)
hGATA1/Me:1
"An erythroid transcription factor (human) that has been methylated on the residue at the position equivalent to Cys-228 of the amino acid sequence represented by UniProtKB:P15976-1. Example: UniProtKB:P15976-1, Cys-228, MOD:00660." [IEDB_epitope:1034875, PRO:DNx]

organism-modification


PR:000073677
erythroid transcription factor methylated 2 (human)
hGATA1/Me:2
"An erythroid transcription factor (human) that has been methylated on the residue at the position equivalent to Cys-282 of the amino acid sequence represented by UniProtKB:P15976-1. Example: UniProtKB:P15976-1, Cys-282, MOD:00660." [IEDB_epitope:1034876, PRO:DNx]

organism-gene


PR:P17678
erythroid transcription factor (chicken)
chick-GATA1
"An erythroid transcription factor that is encoded in the genome of chicken." [PANTHER:PTHR10071:SF26, PRO:DNx]

organism-gene


PR:P17679
erythroid transcription factor (mouse)
mGATA1
"An erythroid transcription factor that is encoded in the genome of mouse." [OMA:P17679, PRO:DNx]

organism-sequence


PR:P17679-1
erythroid transcription factor isoform 1 (mouse)
mGATA1/iso:1
"An erythroid transcription factor isoform 1 that is encoded in the genome of mouse." [PMID:2725678, PRO:HJD]
Yes
organism-modification


PR:000027066
erythroid transcription factor isoform 1 phosphorylated 1 (mouse)
mGATA1/iso:1/Phos:1
"An erythroid transcription factor isoform 1 phosphorylated 1 in mouse. Phosphorylation of Ser-310 is increased upon inducing erythrocyte maturation. UniProtKB:P17679-1, Ser-26/Ser-49/Ser-72/Ser-142/Ser-178/Ser-187/Ser-310, MOD:00046." [PMID:8206977, PRO:HJD]

organism-modification


PR:000027068
erythroid transcription factor isoform 1 sumoylated 1 (mouse)
mGATA1/iso:1/Sumo:1
"An erythroid transcription factor isoform 1 sumoylated 1 in mouse. This form has been sumoylated by PIAS4, a SUMO ligase, on the Lys residue within the motif LKTE located within the transactivation domain. UniProtKB:P17679-1, Lys-137, MOD:01149." [PMID:15173587, PRO:HJD]

organism-sequence


PR:P17679-2
erythroid transcription factor isoform 2 (mouse)
mGATA1/iso:2
"An erythroid transcription factor isoform 2 that is encoded in the genome of mouse. This isoform is produced by alternative initiation." [PMID:8524811, PRO:HJD]
Yes
organism-gene


PR:P43429
erythroid transcription factor (rat)
rGATA1
"An erythroid transcription factor that is encoded in the genome of rat." [OMA:P43429, PRO:DNx]

sequence


PR:000027063
erythroid transcription factor isoform 1
GATA1/iso:1
"An erythroid transcription factor that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P17679-1 or a 1:1 ortholog thereof." [PMID:2725678, PRO:HJD]

organism-sequence


PR:P15976-1
erythroid transcription factor isoform 1 (human)
hGATA1/iso:1
"An erythroid transcription factor isoform 1 that is encoded in the genome of human." [PRO:HJD]

organism-modification


PR:000027073
erythroid transcription factor isoform 1 phosphorylated and sumoylated 1 (human)
hGATA1/iso:1/PhosSumo:1
"An erythroid transcription factor isoform 1 phosphorylated and sumoylated 1 in human. UniProtKB:P15976-1, Lys-137, MOD:01149|Ser-142, MOD:00046." [PMID:16371476, PRO:CNA]

organism-sequence


PR:P17679-1
erythroid transcription factor isoform 1 (mouse)
mGATA1/iso:1
"An erythroid transcription factor isoform 1 that is encoded in the genome of mouse." [PMID:2725678, PRO:HJD]
Yes
organism-modification


PR:000027066
erythroid transcription factor isoform 1 phosphorylated 1 (mouse)
mGATA1/iso:1/Phos:1
"An erythroid transcription factor isoform 1 phosphorylated 1 in mouse. Phosphorylation of Ser-310 is increased upon inducing erythrocyte maturation. UniProtKB:P17679-1, Ser-26/Ser-49/Ser-72/Ser-142/Ser-178/Ser-187/Ser-310, MOD:00046." [PMID:8206977, PRO:HJD]

organism-modification


PR:000027068
erythroid transcription factor isoform 1 sumoylated 1 (mouse)
mGATA1/iso:1/Sumo:1
"An erythroid transcription factor isoform 1 sumoylated 1 in mouse. This form has been sumoylated by PIAS4, a SUMO ligase, on the Lys residue within the motif LKTE located within the transactivation domain. UniProtKB:P17679-1, Lys-137, MOD:01149." [PMID:15173587, PRO:HJD]

modification


PR:000027065
erythroid transcription factor isoform 1 phosphorylated 1
GATA1/iso:1/Phos:1
"An erythroid transcription factor isoform 1 that has been phosphorylated on multiple Ser residues. Example: UniProtKB:P17679-1, Ser-26/Ser-49/Ser-72/Ser-142/Ser-178/Ser-187/Ser-310, MOD:00046." [PMID:8206977, PRO:HJD]

organism-modification


PR:000027066
erythroid transcription factor isoform 1 phosphorylated 1 (mouse)
mGATA1/iso:1/Phos:1
"An erythroid transcription factor isoform 1 phosphorylated 1 in mouse. Phosphorylation of Ser-310 is increased upon inducing erythrocyte maturation. UniProtKB:P17679-1, Ser-26/Ser-49/Ser-72/Ser-142/Ser-178/Ser-187/Ser-310, MOD:00046." [PMID:8206977, PRO:HJD]

modification


PR:000027067
erythroid transcription factor isoform 1 sumoylated 1
GATA1/iso:1/Sumo:1
"An erythroid transcription factor isoform 1 that has been post-translationally modified by sumoylation on the Lys residue within the consensus LKxE motif located within the transactivation domain. Example: UniProtKB:P17679-1, Lys-137, MOD:01149." [PMID:15173587, PRO:HJD]

organism-modification


PR:000027068
erythroid transcription factor isoform 1 sumoylated 1 (mouse)
mGATA1/iso:1/Sumo:1
"An erythroid transcription factor isoform 1 sumoylated 1 in mouse. This form has been sumoylated by PIAS4, a SUMO ligase, on the Lys residue within the motif LKTE located within the transactivation domain. UniProtKB:P17679-1, Lys-137, MOD:01149." [PMID:15173587, PRO:HJD]

modification


PR:000027072
erythroid transcription factor isoform 1 phosphorylated and sumoylated 1
GATA1/iso:1/PhosSumo:1
"An erythroid transcription factor isoform 1 that has been phosphorylated in at least a critical Ser residue within the PsiKxExxSP motif (PDSM motif), and enhancing the sumoylation of the Lys residue within that motif. Example: UniProtKB:P15976-1, Lys-137, MOD:01149|Ser-142, MOD:00046." [PMID:16371476, PRO:CNA]

organism-modification


PR:000027073
erythroid transcription factor isoform 1 phosphorylated and sumoylated 1 (human)
hGATA1/iso:1/PhosSumo:1
"An erythroid transcription factor isoform 1 phosphorylated and sumoylated 1 in human. UniProtKB:P15976-1, Lys-137, MOD:01149|Ser-142, MOD:00046." [PMID:16371476, PRO:CNA]

sequence


PR:000027069
erythroid transcription factor isoform 2
GATA1/iso:2
"An erythroid transcription factor that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P17679-2 or a 1:1 ortholog thereof. This form is created by alternative initiation." [PMID:8524811, PRO:HJD]

organism-sequence


PR:P15976-3
erythroid transcription factor isoform 2 (human)
hGATA1/iso:2
"An erythroid transcription factor isoform 2 that is encoded in the genome of human. This isoform is produced by alternative initiation." [PMID:8524811, PRO:CNA]

organism-sequence


PR:P17679-2
erythroid transcription factor isoform 2 (mouse)
mGATA1/iso:2
"An erythroid transcription factor isoform 2 that is encoded in the genome of mouse. This isoform is produced by alternative initiation." [PMID:8524811, PRO:HJD]
Yes
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Functional Annotation (PRO-centric view) Switch to GO Centric View   
PRO Term GO Annotation Evidence
PR:P17679-1 mGATA1/iso:1 acts_upstream_of_or_withinGO:0045944 positive regulation of transcription by RNA polymerase II MGI_ref:77668; PMID:8524811
enablesGO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific MGI_ref:77668; PMID:8524811
GO:0003712 transcription coregulator activity MGI_ref:77668; PMID:8524811
GO:0008301 DNA binding, bending MGI_ref:4946306; PMID:21436399
GO:0043565 sequence-specific DNA binding MGI_ref:77668; PMID:8524811
located_inGO:0005634 nucleus MGI_ref:77668; PMID:8524811
PR:P17679-2 mGATA1/iso:2
This isoform is produced by alternative initiation		 acts_upstream_of_or_withinGO:0045944 positive regulation of transcription by RNA polymerase II PMID:8524811
enablesGO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific PMID:8524811
GO:0003712 transcription coregulator activity PMID:8524811
GO:0043565 sequence-specific DNA binding PMID:8524811
located_inGO:0005634 nucleus PMID:8524811