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Protein Ontology report - transcriptional activator GLI3
PR:000008028 - http://purl.obolibrary.org/obo/PR_000008028
 
  Protein Forms      
Ontology Information Show OBO stanza
  PRO ID
PR:000008028   
  PRO nametranscriptional activator GLI3 
  Synonyms
PRO-Short-label: EXACT:GLI3
Other: EXACT:GLI3 form of 190 kDa | GLI3 full-length protein | GLI3FL | zinc finger protein GLI3
  Definition"A GLI protein that is a translation product of the human GLI3 gene or a 1:1 ortholog thereof." [PRO:DNx] 
  PRO Categorygene 
  ParentPR:000050018 GLI protein
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Gene1                                                  Organism-Gene 2                                        
         Sequence0                                                  Organism-Sequence 0                                        
         Modification1                                                  Organism-Modification 9                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Protein Forms Switch to Compact View   

Category  
PRO ID
Name
Short Name
Definition
Ann. Has Annotation?

Comp. In Complex?
gene


PR:000008028
transcriptional activator GLI3
GLI3
"A GLI protein that is a translation product of the human GLI3 gene or a 1:1 ortholog thereof." [PRO:DNx]

organism-gene


PR:P10071
transcriptional activator GLI3 (human)
hGLI3
"A transcriptional activator GLI3 that is encoded in the genome of human." [PRO:DNx, UniProtKB:P10071]

organism-modification


PR:000047549
transcriptional activator GLI3 phosphorylated form (human)
hGLI3/PhosRes+
"A transcriptional activator GLI3 (human) that includes at least one phosphorylated residue. UniProtKB:P10071, MOD:00696." [PRO:DNx, Reactome:R-HSA-5635048]

organism-modification


PR:000047548
transcriptional activator GLI3 phosphorylated 1 (human)
hGLI3/Phos:1
"A transcriptional activator GLI3 (human) that has been post-translationally modified to include phosphoserine at positions 849, 865, 877, 907, 980 and 1006 of the amino acid sequence represented by UniProtKB:P10071. UniProtKB:P10071, Ser-849/Ser-865/Ser-877/Ser-907/Ser-980/Ser-1006, MOD:00046." [PRO:DNx, Reactome:R-HSA-5610492]

organism-modification


PR:000061591
transcriptional activator GLI3 phosphorylated 2 (human)
hGLI3/Phos:2
"A transcriptional activator GLI3 (human) that has been phosphorylated on the residues at the positions equivalent to Ser-849, Ser-865, Ser-877, Ser-907, Ser-980, and Ser-1006 of the amino acid sequence represented by UniProtKB:P10071 and that includes at least four additional phosphorylated serines. UniProtKB:P10071, Ser-849/Ser-865/Ser-877/Ser-907/Ser-980/Ser-1006, MOD:00046|MOD:00046(4+)." [PRO:DNx, Reactome:R-HSA-5610454]

organism-modification


PR:000064323
transcriptional activator GLI3 phosphorylated 3 (human)
hGLI3/Phos:3
"A transcriptional activator GLI3 (human) that has been phosphorylated on the residues at the positions equivalent to Ser-849, Ser-865, Ser-877, Ser-907, Ser-980, and Ser-1006 of the amino acid sequence represented by UniProtKB:P10071 and that includes at least seven additional phosphorylated serines. UniProtKB:P10071, Ser-849/Ser-865/Ser-877/Ser-907/Ser-980/Ser-1006, MOD:00046|MOD:00046(7+)." [PRO:DNx, Reactome:R-HSA-5610485]

organism-modification


PR:000064628
transcriptional activator GLI3 phosphorylated and ubiquitinated 1 (human)
hGLI3/PhosUbiq:1
"A transcriptional activator GLI3 (human) that has been phosphorylated on the residues at the positions equivalent to Ser-849, Ser-865, Ser-877, Ser-907, Ser-980 and Ser-1006, and ubiquitinated on the residues at the positions equivalent to Lys-773, Lys-779, Lys-784, and Lys-800 of the amino acid sequence represented by UniProtKB:P10071 and that includes at least seven additional phosphorylated serines. UniProtKB:P10071, Lys-773/Lys-779/Lys-784/Lys-800, MOD:01148|Ser-849/Ser-865/Ser-877/Ser-907/Ser-980/Ser-1006, MOD:00046|MOD:00046(7+)." [PRO:DNx, Reactome:R-HSA-5610506]

organism-modification


PR:000047550
transcriptional activator GLI3 phosphorylated(2+) and ubiquitinated form (human)
hGLI3/Phos(2+)Ubiq+
"A transcriptional activator GLI3 (human) that includes at least two phosphorylated residues and at least one ubiquitinated lysine. UniProtKB:P10071, MOD:00696(2+)|MOD:01148." [PRO:DNx, Reactome:R-HSA-5635060]

organism-modification


PR:000063350
transcriptional activator GLI3 phosphorylated(2+) form (human)
hGLI3/PhosRes(2+)
"A transcriptional activator GLI3 (human) that includes at least two phosphorylated residues. UniProtKB:P10071, MOD:00696(2+)." [PRO:DNx, Reactome:R-HSA-5635052]

organism-gene


PR:Q61602
transcriptional activator GLI3 (mouse)
mGLI3
"A transcriptional activator GLI3 that is encoded in the genome of mouse." [OMA:Q61602, PRO:DNx]

organism-modification


PR:000037267
transcriptional activator GLI3 precursor (mouse)
mGLI3/precursor
"A transcriptional activator GLI3 (mouse) that has not been subjected to any proteolytic cleavage. UniProtKB:Q61602, 1-1583." [PMID:10693759, PRO:KRC]

organism-modification


PR:000037268
transcriptional repressor GLI3R (mouse)
mGLI3/Clv:GLI3R
"A transcriptional activator GLI3 precursor (mouse) that has been processed by proteolytic cleavage, removing the C-terminal region. UniProtKB:Q61602, 1-?." [PMID:10693759, PRO:KRC]

modification


PR:000037271
transcriptional activator GLI3 proteolytic cleavage product
GLI3/ClvPrd
"A transcriptional activator GLI3 that has been processed by proteolytic cleavage." [PRO:CNA, PRO:DAN]

organism-modification


PR:000037268
transcriptional repressor GLI3R (mouse)
mGLI3/Clv:GLI3R
"A transcriptional activator GLI3 precursor (mouse) that has been processed by proteolytic cleavage, removing the C-terminal region. UniProtKB:Q61602, 1-?." [PMID:10693759, PRO:KRC]