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Protein Ontology report - hexokinase-1
PR:000008608 - http://purl.obolibrary.org/obo/PR_000008608
 
  Protein Forms  Annotations      
Ontology Information Show OBO stanza
  PRO ID
PR:000008608   
  PRO namehexokinase-1 
  Synonyms
PRO-Short-label: EXACT:HK1
Other: EXACT:brain form hexokinase | hexokinase type I | hexokinase, tumor isozyme | HK I
  Definition"A protein that is a translation product of the human HK1 gene or a 1:1 ortholog thereof." [PRO:DNx] 
  PRO Categorygene 
  ParentPR:000000001 protein
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Gene1                                                  Organism-Gene 3                                        
         Sequence0                                                  Organism-Sequence 10                                        
         Modification0                                                  Organism-Modification 3                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Protein Forms Switch to Compact View   

Category  

PRO ID

Name

Short Name

Definition

Ann. Has Annotation?

Comp. In Complex?
gene



PR:000008608

hexokinase-1

HK1


"A protein that is a translation product of the human HK1 gene or a 1:1 ortholog thereof." [PRO:DNx]


organism-gene



PR:P05708

hexokinase-1 (rat)

rHK1


"A hexokinase-1 that is encoded in the genome of rat." [OMA:P05708, PRO:DNx]


organism-gene



PR:P17710

hexokinase-1 (mouse)

mHK1


"A hexokinase-1 that is encoded in the genome of mouse." [OMA:P17710, PRO:DNx]


organism-sequence



PR:P17710-1

hexokinase-1 isoform 1 (mouse)

mHK1/iso:1


"A hexokinase-1 (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P17710-1." [PMID:8396993, PRO:HJD]

Yes

organism-sequence



PR:P17710-2

hexokinase-1 isoform 2 (mouse)

mHK1/iso:2


"A hexokinase-1 (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P17710-2." [PMID:8396993, PRO:HJD]


organism-sequence



PR:P17710-3

hexokinase-1 isoform 3 (mouse)

mHK1/iso:3


"A hexokinase-1 (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P17710-3." [PMID:2318862, PRO:HJD]


organism-sequence



PR:P17710-4

hexokinase-1 isoform 4 (mouse)

mHK1/iso:4


"A hexokinase-1 (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P17710-4." [PMID:8396993, PRO:HJD]


organism-gene



PR:P19367

hexokinase-1 (human)

hHK1


"A hexokinase-1 that is encoded in the genome of human." [PRO:DNx, UniProtKB:P19367]


organism-sequence



PR:000062264

hexokinase-1 sequence variant L529S (human)

hHK1/var:L529S


"A hexokinase-1 (human) that has a Ser residue at the position equivalent to Leu-529 of the amino acid sequence represented by UniProtKB:P19367-1. Example: UniProtKB:P19367-1, Leu-529, CHEBI:29999." [PRO:DNx, Reactome:R-HSA-5621861]


organism-sequence



PR:000064212

hexokinase-1 sequence variant T680S (human)

hHK1/var:T680S


"A hexokinase-1 (human) that has a Ser residue at the position equivalent to Thr-680 of the amino acid sequence represented by UniProtKB:P19367-1. Example: UniProtKB:P19367-1, Thr-680, CHEBI:29999." [PRO:DNx, Reactome:R-HSA-5621880]


organism-sequence



PR:P19367-1

hexokinase-1 isoform 1 (human)

hHK1/iso:1


"A hexokinase-1 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P19367-1." [PRO:DNx, UniProtKB:P19367]


organism-sequence



PR:P19367-2

hexokinase-1 isoform h2 (human)

hHK1/iso:h2


"A hexokinase-1 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P19367-2." [PRO:DNx, UniProtKB:P19367]


organism-sequence



PR:P19367-3

hexokinase-1 isoform h3 (human)

hHK1/iso:h3


"A hexokinase-1 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P19367-3." [PRO:DNx, UniProtKB:P19367]


organism-sequence



PR:P19367-4

hexokinase-1 isoform h4 (human)

hHK1/iso:h4


"A hexokinase-1 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P19367-4." [PRO:DNx, UniProtKB:P19367]


organism-modification



PR:000072576

hexokinase-1 methylated 1 (human)

hHK1/Me:1


"A hexokinase-1 (human) that has been methylated on the residue at the position equivalent to Cys-133 of the amino acid sequence represented by UniProtKB:P19367-1. Example: UniProtKB:P19367-1, Cys-133, MOD:00660." [IEDB_epitope:1029126, PRO:DNx]


organism-modification



PR:000073985

hexokinase-1 cysteinylated 1 (human)

hHK1/Cyst:1


"A hexokinase-1 (human) that has been cysteinylated on the residue at the position equivalent to Cys-133 of the amino acid sequence represented by UniProtKB:P19367-1. Example: UniProtKB:P19367-1, Cys-133, MOD:00765." [IEDB_epitope:1584192, IEDB_epitope:929740, PRO:DNx]


organism-modification



PR:000078067

hexokinase-1 deaminated 1 (human)

hHK1/Deam:1


"A hexokinase-1 (human) that has been deaminated on the residue at the position equivalent to Gln-125 of the amino acid sequence represented by UniProtKB:P19367-1. Example: UniProtKB:P19367-1, Gln-125, MOD:00685." [IEDB_epitope:1584191, PRO:DNx]


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Functional Annotation (PRO-centric view) Switch to GO Centric View   
PRO Term GO Annotation Evidence
PR:P17710-1 mHK1/iso:1 acts_upstream_of_or_withinGO:0061621 canonical glycolysis MGI_ref:3814792; PMID:18509164
enablesGO:0004340 glucokinase activity MGI_ref:3814792; PMID:18509164
located_inGO:0005739 mitochondrion MGI_ref:2445910; PMID:12420306
GO:0005929 cilium MGI_ref:3654822; PMID:16687649
GO:0097228 sperm principal piece MGI_ref:4443253; PMID:19889946