back to PRO homepage
  Home |   Linked Open Data |   Browse |  
Search

|   Statistics |   Download
 RACE-PRO
 PRO tracker
 Community
 PRO Consortium
 Publications
 Documentation

Protein Ontology report - hydroxymethylglutaryl-CoA lyase, mitochondrial
PR:000008635 - http://purl.obolibrary.org/obo/PR_000008635
 
  Protein Forms  Annotations      
Ontology Information Show OBO stanza
  PRO ID
PR:000008635   
  PRO namehydroxymethylglutaryl-CoA lyase, mitochondrial 
  Synonyms
PRO-Short-label: EXACT:HMGCL
Other: EXACT:3-hydroxy-3-methylglutarate-CoA lyase | HMG-CoA lyase
RELATED:HL
  Definition"A protein that is a translation product of the human HMGCL gene or a 1:1 ortholog thereof." [PRO:DNx] 
  PRO Categorygene 
  ParentPR:000000001 protein
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Gene1                                                  Organism-Gene 3                                        
         Sequence1                                                  Organism-Sequence 4                                        
         Modification1                                                  Organism-Modification 3                                        
  Term Hierarchy
  Visualization
DAG: OLS:
Back to top
Protein Forms Switch to Compact View   

Category  

PRO ID

Name

Short Name

Definition

Ann. Has Annotation?

Comp. In Complex?
gene



PR:000008635

hydroxymethylglutaryl-CoA lyase, mitochondrial

HMGCL


"A protein that is a translation product of the human HMGCL gene or a 1:1 ortholog thereof." [PRO:DNx]


organism-gene



PR:P35914

hydroxymethylglutaryl-CoA lyase, mitochondrial (human)

hHMGCL


"A hydroxymethylglutaryl-CoA lyase, mitochondrial that is encoded in the genome of human." [PRO:DNx, UniProtKB:P35914]


organism-sequence



PR:P35914-1

hydroxymethylglutaryl-CoA lyase, mitochondrial isoform 1 (human)

hHMGCL/iso:1


"A hydroxymethylglutaryl-CoA lyase, mitochondrial isoform 1 that is encoded in the genome of human." [PMID:8440722, PRO:CNA]


organism-modification



PR:000025736

hydroxymethylglutaryl-CoA lyase, mitochondrial isoform 1 acetylated 1 (human)

hHMGCL/iso:1/Ac:1


"A hydroxymethylglutaryl-CoA lyase, mitochondrial isoform 1 acetylated 1 in human. UniProtKB:P35914-1, Lys-48, MOD:00064." [PMID:19608861, PRO:CNA]


organism-sequence



PR:P35914-2

hydroxymethylglutaryl-CoA lyase, mitochondrial isoform h2 (human)

hHMGCL/iso:h2


"A hydroxymethylglutaryl-CoA lyase, mitochondrial (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P35914-2." [PRO:DNx, UniProtKB:P35914]


organism-sequence



PR:P35914-3

hydroxymethylglutaryl-CoA lyase, mitochondrial isoform h3 (human)

hHMGCL/iso:h3


"A hydroxymethylglutaryl-CoA lyase, mitochondrial (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P35914-3." [PRO:DNx, UniProtKB:P35914]


organism-modification



PR:000047879

hydroxymethylglutaryl-CoA lyase, mitochondrial, transit peptide removed form (human)

hHMGCL/TransPep-


"A hydroxymethylglutaryl-CoA lyase, mitochondrial (human) that has had the transit peptide removed. UniProtKB:P35914, 28-325." [PRO:DNx, Reactome:R-HSA-74172]


organism-gene



PR:P38060

hydroxymethylglutaryl-CoA lyase, mitochondrial (mouse)

mHMGCL


"A hydroxymethylglutaryl-CoA lyase, mitochondrial that is encoded in the genome of mouse." [OMA:P38060, PRO:DNx]


organism-sequence



PR:P38060-1

hydroxymethylglutaryl-CoA lyase, mitochondrial isoform 1 (mouse)

mHMGCL/iso:1


"A hydroxymethylglutaryl-CoA lyase, mitochondrial isoform 1 that is encoded in the genome of mouse." [PMID:8102917, PRO:HJD]

Yes

organism-modification



PR:000025737

hydroxymethylglutaryl-CoA lyase, mitochondrial isoform 1 acetylated 1 (mouse)

mHMGCL/iso:1/Ac:1


"A hydroxymethylglutaryl-CoA lyase, mitochondrial isoform 1 acetylated 1 in mouse. UniProtKB:P38060-1, Lys-48, MOD:00064." [PMID:16916647, PRO:HJD]


organism-gene



PR:P97519

hydroxymethylglutaryl-CoA lyase, mitochondrial (rat)

rHMGCL


"A hydroxymethylglutaryl-CoA lyase, mitochondrial that is encoded in the genome of rat." [OMA:P97519, PRO:DNx]


sequence



PR:000025732

hydroxymethylglutaryl-CoA lyase, mitochondrial isoform 1

HMGCL/iso:1


"A hydroxymethylglutaryl-CoA lyase, mitochondrial that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P38060-1 or a 1:1 ortholog thereof." [PRO:CNA]


organism-sequence



PR:P35914-1

hydroxymethylglutaryl-CoA lyase, mitochondrial isoform 1 (human)

hHMGCL/iso:1


"A hydroxymethylglutaryl-CoA lyase, mitochondrial isoform 1 that is encoded in the genome of human." [PMID:8440722, PRO:CNA]


organism-modification



PR:000025736

hydroxymethylglutaryl-CoA lyase, mitochondrial isoform 1 acetylated 1 (human)

hHMGCL/iso:1/Ac:1


"A hydroxymethylglutaryl-CoA lyase, mitochondrial isoform 1 acetylated 1 in human. UniProtKB:P35914-1, Lys-48, MOD:00064." [PMID:19608861, PRO:CNA]


organism-sequence



PR:P38060-1

hydroxymethylglutaryl-CoA lyase, mitochondrial isoform 1 (mouse)

mHMGCL/iso:1


"A hydroxymethylglutaryl-CoA lyase, mitochondrial isoform 1 that is encoded in the genome of mouse." [PMID:8102917, PRO:HJD]

Yes

organism-modification



PR:000025737

hydroxymethylglutaryl-CoA lyase, mitochondrial isoform 1 acetylated 1 (mouse)

mHMGCL/iso:1/Ac:1


"A hydroxymethylglutaryl-CoA lyase, mitochondrial isoform 1 acetylated 1 in mouse. UniProtKB:P38060-1, Lys-48, MOD:00064." [PMID:16916647, PRO:HJD]


modification



PR:000025735

hydroxymethylglutaryl-CoA lyase, mitochondrial isoform 1 acetylated 1

HMGCL/iso:1/Ac:1


"A hydroxymethylglutaryl-CoA lyase, mitochondrial isoform 1 that has been post-translationally modified to include an N6-acetyllysine at the position equivalent to Lys-48 of the amino acid sequence represented by UniProtKB:P35914-1. Example: UniProtKB:P35914-1, Lys-48, MOD:00064." [PMID:16916647, PMID:19608861, PRO:CNA]


organism-modification



PR:000025736

hydroxymethylglutaryl-CoA lyase, mitochondrial isoform 1 acetylated 1 (human)

hHMGCL/iso:1/Ac:1


"A hydroxymethylglutaryl-CoA lyase, mitochondrial isoform 1 acetylated 1 in human. UniProtKB:P35914-1, Lys-48, MOD:00064." [PMID:19608861, PRO:CNA]


organism-modification



PR:000025737

hydroxymethylglutaryl-CoA lyase, mitochondrial isoform 1 acetylated 1 (mouse)

mHMGCL/iso:1/Ac:1


"A hydroxymethylglutaryl-CoA lyase, mitochondrial isoform 1 acetylated 1 in mouse. UniProtKB:P38060-1, Lys-48, MOD:00064." [PMID:16916647, PRO:HJD]


Back to top
Functional Annotation (PRO-centric view) Switch to GO Centric View   
PRO Term GO Annotation Evidence
PR:P38060-1 mHMGCL/iso:1 located_inGO:0005739 mitochondrion PMID:14651853; PMID:18614015
GO:0005743 mitochondrial inner membrane PMID:12865426