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Protein Ontology report - insulin receptor substrate 1
PR:000009107 - http://purl.obolibrary.org/obo/PR_000009107
 
  Protein Forms      
Ontology Information Show OBO stanza
  PRO ID
PR:000009107   
  PRO nameinsulin receptor substrate 1 
  Synonyms
PRO-Short-label: EXACT:IRS1
Other: EXACT:IRS-1
  Definition"A protein that is a translation product of the human IRS1 gene or a 1:1 ortholog thereof." [PRO:DNx] 
  PRO Categorygene 
  ParentPR:000000001 protein
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Gene1                                                  Organism-Gene 3                                        
         Sequence0                                                  Organism-Sequence 0                                        
         Modification0                                                  Organism-Modification 7                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Protein Forms Switch to Compact View   

Category  

PRO ID

Name

Short Name

Definition

Ann. Has Annotation?

Comp. In Complex?
gene



PR:000009107

insulin receptor substrate 1

IRS1


"A protein that is a translation product of the human IRS1 gene or a 1:1 ortholog thereof." [PRO:DNx]


organism-gene



PR:P35568

insulin receptor substrate 1 (human)

hIRS1


"An insulin receptor substrate 1 that is encoded in the genome of human." [PRO:DNx, UniProtKB:P35568]


organism-modification



PR:000045764

insulin receptor substrate 1 phosphorylated 1 (human)

hIRS1/Phos:1


"An insulin receptor substrate 1 (human) that has been phosphorylated at Ser-794. UniProtKB:P35568, Ser-794, MOD:00046." [iPTMnet:P35568, PMID:12624099]


organism-modification



PR:000048052

insulin receptor substrate 1 phosphotyrosine form (human)

hIRS1/PhosTyr+


"An insulin receptor substrate 1 (human) that includes at least one phosphorylated tyrosine. UniProtKB:P35568, MOD:00048." [PRO:DNx, Reactome:R-HSA-198366, Reactome:R-HSA-74772]


organism-modification



PR:000048051

insulin receptor substrate 1 phosphorylated 2 (human)

hIRS1/Phos:2


"An insulin receptor substrate 1 (human) that has been post-translationally modified to include phosphotyrosine at positions 612, 662, 732, 896, 941 and 1179 of the amino acid sequence represented by UniProtKB:P35568. UniProtKB:P35568, Tyr-612/Tyr-662/Tyr-732/Tyr-896/Tyr-941/Tyr-1179, MOD:00048." [PRO:DNx, Reactome:R-HSA-2445090]


organism-modification



PR:000067069

insulin receptor substrate 1 phosphorylated 3 (human)

hIRS1/Phos:3


"An insulin receptor substrate 1 (human) that has been phosphorylated on the residue at the position equivalent to Tyr-1229 of the amino acid sequence represented by UniProtKB:P35568. UniProtKB:P35568, Tyr-1229, MOD:00048." [IEDB_epitope:1363086, PRO:DNx]


organism-modification



PR:000084284

insulin receptor substrate 1 methylated 1 (human)

hIRS1/Me:1


"An insulin receptor substrate 1 (human) that has been methylated on the residue at the position equivalent to Cys-728 of the amino acid sequence represented by UniProtKB:P35568. UniProtKB:P35568, Cys-728, MOD:00660." [IEDB_epitope:1009283, PRO:DNx]


organism-gene



PR:P35569

insulin receptor substrate 1 (mouse)

mIRS1


"An insulin receptor substrate 1 that is encoded in the genome of mouse." [OMA:P35569, PRO:DNx]


organism-modification



PR:000046171

insulin receptor substrate 1 phosphorylated 1 (mouse)

mIRS1/Phos:1


"An insulin receptor substrate 1 (mouse) that has been phosphorylated at Ser-307. UniProtKB:P35569, Ser-307, MOD:00046." [iPTMnet:P35569, PMID:14998989, PMID:15314024]


organism-gene



PR:P35570

insulin receptor substrate 1 (rat)

rIRS1


"An insulin receptor substrate 1 that is encoded in the genome of rat." [OMA:P35570, PRO:DNx]


organism-modification



PR:000046172

insulin receptor substrate 1 phosphorylated 1 (rat)

rIRS1/Phos:1


"An insulin receptor substrate 1 (rat) that has been phosphorylated at Ser-522. UniProtKB:P35570, Ser-522, MOD:00046." [iPTMnet:P35570, PMID:17579213]