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Protein Ontology report - L-lactate dehydrogenase A chain
PR:000009739 - http://purl.obolibrary.org/obo/PR_000009739
 
  Protein Forms  Complex      
Ontology Information Show OBO stanza
  PRO ID
PR:000009739   
  PRO nameL-lactate dehydrogenase A chain 
  Synonyms
PRO-Short-label: EXACT:LDHA
Gene-based: RELATED:Ldh-1 | Ldh1 | PIG19
Other: EXACT:cell proliferation-inducing gene 19 protein | LDH muscle subunit | LDH-A | LDH-M | renal carcinoma antigen NY-REN-59
  Definition"An L-lactate dehydrogenase, cytoplasmic that is a translation product of the human LDHA gene or a 1:1 ortholog thereof." [PRO:DNx] 
  PRO Categorygene 
  ParentPR:000050332 L-lactate dehydrogenase, cytoplasmic
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Gene1                                                  Organism-Gene 8                                        
         Sequence0                                                  Organism-Sequence 5                                        
         Modification1                                                  Organism-Modification 7                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Protein Forms Switch to Compact View   

Category  

PRO ID

Name

Short Name

Definition

Ann. Has Annotation?

Comp. In Complex?
gene



PR:000009739

L-lactate dehydrogenase A chain

LDHA


"An L-lactate dehydrogenase, cytoplasmic that is a translation product of the human LDHA gene or a 1:1 ortholog thereof." [PRO:DNx]


Yes
organism-gene



PR:P00338

L-lactate dehydrogenase A chain (human)

hLDHA


"An L-lactate dehydrogenase A chain that is encoded in the genome of human." [PRO:DNx, UniProtKB:P00338]


organism-sequence



PR:P00338-1

L-lactate dehydrogenase A chain isoform h1 (human)

hLDHA/iso:h1


"An L-lactate dehydrogenase A chain (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P00338-1." [PRO:DNx, UniProtKB:P00338]


organism-sequence



PR:P00338-2

L-lactate dehydrogenase A chain isoform h2 (human)

hLDHA/iso:h2


"An L-lactate dehydrogenase A chain (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P00338-2." [PRO:DNx, UniProtKB:P00338]


organism-sequence



PR:P00338-3

L-lactate dehydrogenase A chain isoform h3 (human)

hLDHA/iso:h3


"An L-lactate dehydrogenase A chain (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P00338-3." [PRO:DNx, UniProtKB:P00338]


organism-sequence



PR:P00338-4

L-lactate dehydrogenase A chain isoform h4 (human)

hLDHA/iso:h4


"An L-lactate dehydrogenase A chain (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P00338-4." [PRO:DNx, UniProtKB:P00338]


organism-sequence



PR:P00338-5

L-lactate dehydrogenase A chain isoform h5 (human)

hLDHA/iso:h5


"An L-lactate dehydrogenase A chain (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P00338-5." [PRO:DNx, UniProtKB:P00338]


organism-modification



PR:000048179

L-lactate dehydrogenase A chain, initiator methionine removed form (human)

hLDHA/InitMet-


"An L-lactate dehydrogenase A chain (human) that has had the initiator methionine removed. UniProtKB:P00338, 2-332." [PRO:DNx, Reactome:R-HSA-70502]


Yes
organism-modification



PR:000068524

L-lactate dehydrogenase A chain methylated 1 (human)

hLDHA/Me:1


"An L-lactate dehydrogenase A chain (human) that has been methylated on the residue at the position equivalent to Cys-293 of the amino acid sequence represented by UniProtKB:P00338-1. Example: UniProtKB:P00338-1, Cys-293, MOD:00660." [IEDB_epitope:1057360, PRO:DNx]


organism-modification



PR:000072366

L-lactate dehydrogenase A chain glutathionylated 1 (human)

hLDHA/SGlt:1


"An L-lactate dehydrogenase A chain (human) that has been glutathionylated on the residue at the position equivalent to Cys-131 of the amino acid sequence represented by UniProtKB:P00338-1. Example: UniProtKB:P00338-1, Cys-131, MOD:00234." [IEDB_epitope:744608, PRO:DNx]


organism-modification



PR:000074825

L-lactate dehydrogenase A chain deaminated 1 (human)

hLDHA/Deam:1


"An L-lactate dehydrogenase A chain (human) that has been deaminated on the residue at the position equivalent to Gln-111 of the amino acid sequence represented by UniProtKB:P00338-1. Example: UniProtKB:P00338-1, Gln-111, MOD:00685." [IEDB_epitope:1990225, PRO:DNx]


organism-modification



PR:000082679

L-lactate dehydrogenase A chain hydroxylated 1 (human)

hLDHA/Hy:1


"An L-lactate dehydrogenase A chain (human) that has been hydroxylated on the residue at the position equivalent to Trp-324 of the amino acid sequence represented by UniProtKB:P00338-1. Example: UniProtKB:P00338-1, Trp-324, MOD:01622." [IEDB_epitope:1325702, PRO:DNx]


organism-modification



PR:000082816

L-lactate dehydrogenase A chain methylated 2 (human)

hLDHA/Me:2


"An L-lactate dehydrogenase A chain (human) that has been methylated on the residue at the position equivalent to Cys-131 of the amino acid sequence represented by UniProtKB:P00338-1. Example: UniProtKB:P00338-1, Cys-131, MOD:00660." [IEDB_epitope:1027996, IEDB_epitope:1027997, IEDB_epitope:1050797, IEDB_epitope:1062532, PRO:DNx]


organism-modification



PR:000083019

L-lactate dehydrogenase A chain cysteinylated 1 (human)

hLDHA/Cyst:1


"An L-lactate dehydrogenase A chain (human) that has been cysteinylated on the residue at the position equivalent to Cys-293 of the amino acid sequence represented by UniProtKB:P00338-1. Example: UniProtKB:P00338-1, Cys-293, MOD:00765." [IEDB_epitope:1057359, PRO:DNx]


organism-gene



PR:P00340

L-lactate dehydrogenase A chain (chicken)

chick-LDHA


"An L-lactate dehydrogenase A chain that is encoded in the genome of chicken." [OMA:P00340, PRO:DNx]


organism-gene



PR:P04642

L-lactate dehydrogenase A chain (rat)

rLDHA


"An L-lactate dehydrogenase A chain that is encoded in the genome of rat." [OMA:P04642, PRO:DNx]


organism-gene



PR:P06151

L-lactate dehydrogenase A chain (mouse)

mLDHA


"An L-lactate dehydrogenase A chain that is encoded in the genome of mouse." [OMA:P06151, PRO:DAN]


organism-gene



PR:Q27888

L-lactate dehydrogenase (worm)

LDHA (worm)


"An L-lactate dehydrogenase A chain that is encoded in the genome of worm." [OMA:Q27888, PRO:DNx]


organism-gene



PR:Q95028

L-lactate dehydrogenase (fruit fly)

fly-LDHA


"An L-lactate dehydrogenase A chain that is encoded in the genome of fruit fly." [OMA:Q95028, PRO:DNx]


organism-gene



PR:Q9P7P7

probable L-lactate dehydrogenase (Schizosaccharomyces pombe 972h-)

Spom972h-LDHA


"An L-lactate dehydrogenase A chain that is encoded in the genome of Schizosaccharomyces pombe 972h-." [PRO:DNx]


organism-gene



PR:Q9PVK5

L-lactate dehydrogenase A chain (zebrafish)

z-ldha


"An L-lactate dehydrogenase A chain that is a translation product of the ldha gene in zebrafish." [PRO:DNx, UniProtKB:Q9PVK5]


modification



PR:000020451

L-lactate dehydrogenase A chain, initiator methionine removed form

LDHA/InitMet-


"An L-lactate dehydrogenase A chain that has had the initiator methionine removed." [PRO:DNx]


organism-modification



PR:000048179

L-lactate dehydrogenase A chain, initiator methionine removed form (human)

hLDHA/InitMet-


"An L-lactate dehydrogenase A chain (human) that has had the initiator methionine removed. UniProtKB:P00338, 2-332." [PRO:DNx, Reactome:R-HSA-70502]


Yes
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LDHA forms found in complexes   

LDHA Component
Complexes
PR:000009739 LDHA PR:000050327 lactate dehydrogenase complex 2
PR:000050328 lactate dehydrogenase complex 3
PR:000050329 lactate dehydrogenase complex 4
PR:000050330 lactate dehydrogenase complex 5
PR:000048179 hLDHA/InitMet- PR:000050363 lactate dehydrogenase complex 2 (human)
PR:000050364 lactate dehydrogenase complex 3 (human)
PR:000050365 lactate dehydrogenase complex 4 (human)
PR:000050366 lactate dehydrogenase complex 5 (human)