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Protein Ontology report - low-density lipoprotein receptor-related protein 6
PR:000009927 - http://purl.obolibrary.org/obo/PR_000009927
 
  Protein Forms      
Ontology Information Show OBO stanza
  PRO ID
PR:000009927   
  PRO namelow-density lipoprotein receptor-related protein 6 
  Synonyms
PRO-Short-label: EXACT:LRP6
Other: EXACT:LRP-6
  Definition"A protein that is a translation product of the human LRP6 gene or a 1:1 ortholog thereof." [PRO:DNx] 
  PRO Categorygene 
  ParentPR:000000001 protein
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Gene1                                                  Organism-Gene 2                                        
         Sequence1                                                  Organism-Sequence 2                                        
         Modification0                                                  Organism-Modification 7                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Protein Forms Switch to Compact View   

Category  

PRO ID

Name

Short Name

Definition

Ann. Has Annotation?

Comp. In Complex?
gene



PR:000009927

low-density lipoprotein receptor-related protein 6

LRP6


"A protein that is a translation product of the human LRP6 gene or a 1:1 ortholog thereof." [PRO:DNx]


organism-gene



PR:O75581

low-density lipoprotein receptor-related protein 6 (human)

hLRP6


"A low-density lipoprotein receptor-related protein 6 that is encoded in the genome of human." [PRO:DNx, UniProtKB:O75581]


organism-sequence



PR:O75581-1

low-density lipoprotein receptor-related protein 6 isoform 1 (human)

hLRP6/iso:1


"A low-density lipoprotein receptor-related protein 6 isoform 1 that is encoded in the genome of human." [PRO:DNx]


organism-modification



PR:000048251

low-density lipoprotein receptor-related protein 6, signal peptide removed form (human)

hLRP6/SigPep-


"A low-density lipoprotein receptor-related protein 6 (human) that has had the signal peptide removed. UniProtKB:O75581, 20-1613." [PRO:DNx, Reactome:R-HSA-206252, Reactome:R-HSA-5368481]


organism-modification



PR:000060381

low-density lipoprotein receptor-related protein 6, signal peptide removed phosphorylated 1 (human)

hLRP6/SigPep-/Phos:1


"A low-density lipoprotein receptor-related protein 6 (human) that has had the signal peptide removed and that has been phosphorylated on the residue at the position equivalent to Ser-1490 of the amino acid sequence represented by UniProtKB:O75581. UniProtKB:O75581, 20-1613, Ser-1490, MOD:00046." [PRO:DNx, Reactome:R-HSA-206156]


organism-modification



PR:000061242

low-density lipoprotein receptor-related protein 6, signal peptide removed phosphorylated 2 (human)

hLRP6/SigPep-/Phos:2


"A low-density lipoprotein receptor-related protein 6 (human) that has had the signal peptide removed and that has been phosphorylated on the residues at the positions equivalent to Thr-1479, Ser-1490, and Thr-1493 of the amino acid sequence represented by UniProtKB:O75581. UniProtKB:O75581, 20-1613, Thr-1479/Thr-1493, MOD:00047|Ser-1490, MOD:00046." [PRO:DNx, Reactome:R-HSA-205884]


organism-modification



PR:000061765

low-density lipoprotein receptor-related protein 6, signal peptide removed phosphoserine(5+) and phosphothreonine(5+) form (human)

hLRP6/SigPep-/Phos:3


"A low-density lipoprotein receptor-related protein 6 (human) that has had the signal peptide removed, that has been phosphorylated on the residues at the positions equivalent to Thr-1479, Ser-1490, and Thr-1493 of the amino acid sequence represented by UniProtKB:O75581, and that includes at least three additional phosphorylated threonines and at least four additional phosphorylated serines. UniProtKB:O75581, 20-1613, Thr-1479/Thr-1493, MOD:00047|Ser-1490, MOD:00046|MOD:00046(4+)|MOD:00047(3+)." [PRO:DNx, Reactome:R-HSA-1458895, Reactome:R-HSA-5368496]


organism-modification



PR:000063545

low-density lipoprotein receptor-related protein 6, signal peptide removed phosphoserine(2+) and phosphothreonine(2+) form (human)

hLRP6/SigPep-/Phos:4


"A low-density lipoprotein receptor-related protein 6 (human) that has had the signal peptide removed, that has been phosphorylated on the residue at the position equivalent to Ser-1490 of the amino acid sequence represented by UniProtKB:O75581, and that includes at least two additional phosphorylated serines and at least two phosphorylated threonines. UniProtKB:O75581, 20-1613, Ser-1490, MOD:00046|MOD:00046(2+)|MOD:00047(2+)." [PRO:DNx, Reactome:R-HSA-1458894]


organism-modification



PR:000084283

low-density lipoprotein receptor-related protein 6 cysteinylated 1 (human)

hLRP6/Cyst:1


"A low-density lipoprotein receptor-related protein 6 (human) that has been cysteinylated on the residue at the position equivalent to Cys-627 of the amino acid sequence represented by UniProtKB:O75581. UniProtKB:O75581, Cys-627, MOD:00765." [IEDB_epitope:2123483, IEDB_epitope:2123484, PRO:DNx]


organism-gene



PR:O88572

low-density lipoprotein receptor-related protein 6 (mouse)

mLRP6


"A low-density lipoprotein receptor-related protein 6 that is encoded in the genome of mouse." [OMA:O88572, PRO:DNx]


organism-sequence



PR:O88572-1

low-density lipoprotein receptor-related protein 6 isoform 1 (mouse)

mLRP6/iso:1


"A low-density lipoprotein receptor-related protein 6 isoform 1 that is encoded in the genome of mouse." [PRO:DNx]


organism-modification



PR:000046118

low-density lipoprotein receptor-related protein 6 phosphorylated 1 (mouse)

mLrp6/Phos:1


"A low-density lipoprotein receptor-related protein 6 (mouse) that has been phosphorylated at Ser-1579. UniProtKB:O88572, Ser-1579, MOD:00046." [iPTMnet:O88572, PMID:22491013]


sequence



PR:000038376

low-density lipoprotein receptor-related protein 6 isoform 1

LRP6/iso:1


"A low-density lipoprotein receptor-related protein 6 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:O75581-1 or a 1:1 ortholog thereof." [PRO:DNx]


organism-sequence



PR:O75581-1

low-density lipoprotein receptor-related protein 6 isoform 1 (human)

hLRP6/iso:1


"A low-density lipoprotein receptor-related protein 6 isoform 1 that is encoded in the genome of human." [PRO:DNx]


organism-sequence



PR:O88572-1

low-density lipoprotein receptor-related protein 6 isoform 1 (mouse)

mLRP6/iso:1


"A low-density lipoprotein receptor-related protein 6 isoform 1 that is encoded in the genome of mouse." [PRO:DNx]