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Protein Ontology report - lanosterol synthase
PR:000009969 - http://purl.obolibrary.org/obo/PR_000009969
 
  Protein Forms      
Ontology Information Show OBO stanza
  PRO ID
PR:000009969   
  PRO namelanosterol synthase 
  Synonyms
PRO-Short-label: EXACT:LSS
Gene-based: RELATED:OSC
Other: EXACT:2,3-epoxysqualene--lanosterol cyclase | oxidosqualene--lanosterol cyclase
  Definition"A protein that is a translation product of the human LSS gene or a 1:1 ortholog thereof." [PRO:DNx] 
  PRO Categorygene 
  ParentPR:000000001 protein
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Gene1                                                  Organism-Gene 7                                        
         Sequence1                                                  Organism-Sequence 5                                        
         Modification1                                                  Organism-Modification 13                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Related Cross References

  Db identifiers
IUPHARobj:2434
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Protein Forms Switch to Compact View   

Category  
PRO ID
Name
Short Name
Definition
Ann. Has Annotation?

Comp. In Complex?
gene


PR:000009969
lanosterol synthase
LSS
"A protein that is a translation product of the human LSS gene or a 1:1 ortholog thereof." [PRO:DNx]

organism-gene


PR:P33247
squalene--hopene cyclase (Alicyclobacillus acidocaldarius subsp. acidocaldarius DSM 446)
LSS (ALIAD)
"A lanosterol synthase that is encoded in the genome of Alicyclobacillus acidocaldarius subsp. acidocaldarius DSM 446." [OMA:P33247, PRO:DNx]

organism-gene


PR:P38604
lanosterol synthase ERG7 (yeast)
yLSS
"A lanosterol synthase that is encoded in the genome of yeast." [OMA:P38604, PRO:DNx]

organism-gene


PR:P48449
lanosterol synthase (human)
hLSS
"A lanosterol synthase that is encoded in the genome of human." [PRO:DNx, UniProtKB:P48449]

organism-sequence


PR:P48449-1
lanosterol synthase isoform h1 (human)
hLSS/iso:h1
"A lanosterol synthase (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P48449-1." [PRO:DNx, UniProtKB:P48449]

organism-sequence


PR:P48449-2
lanosterol synthase isoform h2 (human)
hLSS/iso:h2
"A lanosterol synthase (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P48449-2." [PRO:DNx, UniProtKB:P48449]

organism-sequence


PR:P48449-3
lanosterol synthase isoform h3 (human)
hLSS/iso:h3
"A lanosterol synthase (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P48449-3." [PRO:DNx, UniProtKB:P48449]

organism-modification


PR:000048264
lanosterol synthase, initiator methionine removed form (human)
hLSS/InitMet-
"A lanosterol synthase (human) that has had the initiator methionine removed. UniProtKB:P48449, 2-732." [PRO:DNx, Reactome:R-HSA-191371]

organism-modification


PR:000066269
lanosterol synthase methylated 1 (human)
hLSS/Me:1
"A lanosterol synthase (human) that has been methylated on the residue at the position equivalent to Cys-676 of the amino acid sequence represented by UniProtKB:P48449-1. Example: UniProtKB:P48449-1, Cys-676, MOD:00660." [IEDB_epitope:1001672, PRO:DNx]

organism-modification


PR:000066477
lanosterol synthase methylated 2 (human)
hLSS/Me:2
"A lanosterol synthase (human) that has been methylated on the residue at the position equivalent to Cys-653 of the amino acid sequence represented by UniProtKB:P48449-1. Example: UniProtKB:P48449-1, Cys-653, MOD:00660." [IEDB_epitope:1002007, IEDB_epitope:1039427, PRO:DNx]

organism-modification


PR:000067863
lanosterol synthase methylated 3 (human)
hLSS/Me:3
"A lanosterol synthase (human) that has been methylated on the residue at the position equivalent to Cys-243 of the amino acid sequence represented by UniProtKB:P48449-1. Example: UniProtKB:P48449-1, Cys-243, MOD:00660." [IEDB_epitope:1060160, PRO:DNx]

organism-modification


PR:000069138
lanosterol synthase cysteinylated 1 (human)
hLSS/Cyst:1
"A lanosterol synthase (human) that has been cysteinylated on the residue at the position equivalent to Cys-410 of the amino acid sequence represented by UniProtKB:P48449-1. Example: UniProtKB:P48449-1, Cys-410, MOD:00765." [IEDB_epitope:1019195, PRO:DNx]

organism-modification


PR:000069521
lanosterol synthase cysteinylated 2 (human)
hLSS/Cyst:2
"A lanosterol synthase (human) that has been cysteinylated on the residue at the position equivalent to Cys-243 of the amino acid sequence represented by UniProtKB:P48449-1. Example: UniProtKB:P48449-1, Cys-243, MOD:00765." [IEDB_epitope:1060159, PRO:DNx]

organism-modification


PR:000070500
lanosterol synthase methylated 4 (human)
hLSS/Me:4
"A lanosterol synthase (human) that has been methylated on the residue at the position equivalent to Cys-616 of the amino acid sequence represented by UniProtKB:P48449-1. Example: UniProtKB:P48449-1, Cys-616, MOD:00660." [IEDB_epitope:999106, PRO:DNx]

organism-modification


PR:000071138
lanosterol synthase methylated 5 (human)
hLSS/Me:5
"A lanosterol synthase (human) that has been methylated on the residue at the position equivalent to Cys-410 of the amino acid sequence represented by UniProtKB:P48449-1. Example: UniProtKB:P48449-1, Cys-410, MOD:00660." [IEDB_epitope:1019196, PRO:DNx]

organism-modification


PR:000072802
lanosterol synthase methylated 6 (human)
hLSS/Me:6
"A lanosterol synthase (human) that has been methylated on the residue at the position equivalent to Cys-29 of the amino acid sequence represented by UniProtKB:P48449-1. Example: UniProtKB:P48449-1, Cys-29, MOD:00660." [IEDB_epitope:1043201, PRO:DNx]

organism-modification


PR:000078372
lanosterol synthase deaminated 1 (human)
hLSS/Deam:1
"A lanosterol synthase (human) that has been deaminated on the residue at the position equivalent to Gln-257 of the amino acid sequence represented by UniProtKB:P48449-1. Example: UniProtKB:P48449-1, Gln-257, MOD:00685." [IEDB_epitope:1738042, IEDB_epitope:1738045, PRO:DNx]

organism-modification


PR:000079601
lanosterol synthase methylated 7 (human)
hLSS/Me:7
"A lanosterol synthase (human) that has been methylated on the residue at the position equivalent to Cys-598 of the amino acid sequence represented by UniProtKB:P48449-1. Example: UniProtKB:P48449-1, Cys-598, MOD:00660." [IEDB_epitope:999189, PRO:DNx]

organism-modification


PR:000082157
lanosterol synthase cysteinylated 3 (human)
hLSS/Cyst:3
"A lanosterol synthase (human) that has been cysteinylated on the residue at the position equivalent to Cys-609 of the amino acid sequence represented by UniProtKB:P48449-1. Example: UniProtKB:P48449-1, Cys-609, MOD:00765." [IEDB_epitope:2126585, PRO:DNx]

organism-modification


PR:000085114
lanosterol synthase methylated 8 (human)
hLSS/Me:8
"A lanosterol synthase (human) that has been methylated on the residue at the position equivalent to Cys-700 of the amino acid sequence represented by UniProtKB:P48449-1. Example: UniProtKB:P48449-1, Cys-700, MOD:00660." [IEDB_epitope:1003856, PRO:DNx]

organism-gene


PR:P48450
lanosterol synthase (rat)
rLSS
"A lanosterol synthase that is encoded in the genome of rat." [OMA:P48450, PRO:DNx]

organism-sequence


PR:P48450-1
lanosterol synthase isoform 1 (rat)
rLSS/iso:1
"A lanosterol synthase isoform 1 that is encoded in the genome of rat." [PRO:DNx]

organism-gene


PR:Q10231
lanosterol synthase erg7 (Schizosaccharomyces pombe 972h-)
Spom972h-LSS
"A lanosterol synthase that is encoded in the genome of Schizosaccharomyces pombe 972h-." [OMA:Q10231, PRO:DNx]

organism-gene


PR:Q55D85
cycloartenol synthase (Dictyostelium discoideum)
Dicty-LSS
"A lanosterol synthase that is encoded in the genome of Dictyostelium discoideum." [OMA:Q55D85, PRO:DNx]

organism-gene


PR:Q8BLN5
lanosterol synthase (mouse)
mLSS
"A lanosterol synthase that is encoded in the genome of mouse." [OMA:Q8BLN5, PRO:DNx]

organism-sequence


PR:Q8BLN5-1
lanosterol synthase isoform 1 (mouse)
mLSS/iso:1
"A lanosterol synthase isoform 1 that is encoded in the genome of mouse." [PRO:DNx]

sequence


PR:000041595
lanosterol synthase isoform 1
LSS/iso:1
"A lanosterol synthase that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q8BLN5-1 or a 1:1 ortholog thereof." [PRO:DNx]

organism-sequence


PR:P48450-1
lanosterol synthase isoform 1 (rat)
rLSS/iso:1
"A lanosterol synthase isoform 1 that is encoded in the genome of rat." [PRO:DNx]

organism-sequence


PR:Q8BLN5-1
lanosterol synthase isoform 1 (mouse)
mLSS/iso:1
"A lanosterol synthase isoform 1 that is encoded in the genome of mouse." [PRO:DNx]

modification


PR:000026640
lanosterol synthase, initiator methionine removed form
LSS/InitMet-
"A lanosterol synthase that has had the initiator methionine removed." [PRO:DNx]

organism-modification


PR:000048264
lanosterol synthase, initiator methionine removed form (human)
hLSS/InitMet-
"A lanosterol synthase (human) that has had the initiator methionine removed. UniProtKB:P48449, 2-732." [PRO:DNx, Reactome:R-HSA-191371]