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Protein Ontology report - tyrosine-protein kinase Lyn
PR:000010002 - http://purl.obolibrary.org/obo/PR_000010002
 
  Protein Forms      
Ontology Information Show OBO stanza
  PRO ID
PR:000010002   
  PRO nametyrosine-protein kinase Lyn 
  Synonyms
PRO-Short-label: EXACT:LYN
Gene-based: RELATED:JTK8
Other: EXACT:p53Lyn | p56Lyn | V-yes-1 Yamaguchi sarcoma viral related oncogene homolog
  Definition"A proto-oncogene SRC-like tyrosine-protein kinase that is a translation product of the human LYN gene or a 1:1 ortholog thereof." [PRO:DNx] 
  PRO Categorygene 
  ParentPR:000002997 proto-oncogene SRC-like tyrosine-protein kinase
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Gene1                                                  Organism-Gene 3                                        
         Sequence2                                                  Organism-Sequence 6                                        
         Modification0                                                  Organism-Modification 6                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Related Cross References

  Db identifiers
IUPHARobj:2060
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Protein Forms Switch to Compact View   

Category  
PRO ID
Name
Short Name
Definition
Ann. Has Annotation?

Comp. In Complex?
gene


PR:000010002
tyrosine-protein kinase Lyn
LYN
"A proto-oncogene SRC-like tyrosine-protein kinase that is a translation product of the human LYN gene or a 1:1 ortholog thereof." [PRO:DNx]

organism-gene


PR:P07948
tyrosine-protein kinase Lyn (human)
hLYN
"A tyrosine-protein kinase Lyn that is encoded in the genome of human." [PRO:DNx, UniProtKB:P07948]

organism-sequence


PR:P07948-1
tyrosine-protein kinase Lyn isoform 1 (human)
hLYN/iso:1
"A tyrosine-protein kinase Lyn isoform 1 that is encoded in the genome of human." [PRO:DNx]

organism-sequence


PR:P07948-2
tyrosine-protein kinase Lyn isoform 2 (human)
hLYN/iso:2
"A tyrosine-protein kinase Lyn isoform 2 that is encoded in the genome of human." [PRO:DNx]

organism-modification


PR:000045652
tyrosine-protein kinase Lyn phosphorylated 1 (human)
hLYN/Phos:1
"A tyrosine-protein kinase Lyn (human) that has been phosphorylated on the residue at the position equivalent to Tyr-32 of the amino acid sequence represented by UniProtKB:P07948-1. Example: UniProtKB:P07948-1, Tyr-32, MOD:00048." [iPTMnet:P07948, PMID:23764002]

organism-modification


PR:000048278
tyrosine-protein kinase Lyn, initiator methionine removed form (human)
hLYN/InitMet-
"A tyrosine-protein kinase Lyn (human) that has had the initiator methionine removed. UniProtKB:P07948, 2-512." [PRO:DNx, Reactome:R-HSA-197943, Reactome:R-HSA-354251]

organism-modification


PR:000048279
tyrosine-protein kinase Lyn, initiator methionine removed phosphorylated 2 (human)
hLYN/InitMet-/Phos:2
"A tyrosine-protein kinase Lyn (human) that has had the initiator methionine removed and has been post-translationally modified to include phosphotyrosine at position 397 of the amino acid sequence represented by UniProtKB:P07948. UniProtKB:P07948, 2-512, Tyr-397, MOD:00048." [PRO:DAN, Reactome:R-HSA-2454229]

organism-modification


PR:000063476
tyrosine-protein kinase Lyn, initiator methionine removed myristoylated and palmitoylated 1 (human)
hLYN/InitMet-/MyrPalm:1
"A tyrosine-protein kinase Lyn (human) that has had the initiator methionine removed and that has been myristoylated on the residue at the position equivalent to Gly-2 and palmitoylated on the residue at the position equivalent to Cys-3 of the amino acid sequence represented by UniProtKB:P07948-1. Example: UniProtKB:P07948-1, 2-512, Gly-2, MOD:00068|Cys-3, MOD:00115." [PRO:DNx, Reactome:R-HSA-9606875, Reactome:R-HSA-9705728, Reactome:R-HSA-9707903]

organism-modification


PR:000072851
tyrosine-protein kinase Lyn methylated 1 (human)
hLYN/Me:1
"A tyrosine-protein kinase Lyn (human) that has been methylated on the residue at the position equivalent to Cys-381 of the amino acid sequence represented by UniProtKB:P07948-1. Example: UniProtKB:P07948-1, Cys-381, MOD:00660." [IEDB_epitope:1058333, PRO:DNx]

organism-modification


PR:000077386
tyrosine-protein kinase Lyn deaminated 1 (human)
hLYN/Deam:1
"A tyrosine-protein kinase Lyn (human) that has been deaminated on the residue at the position equivalent to Asn-190 of the amino acid sequence represented by UniProtKB:P07948-1. Example: UniProtKB:P07948-1, Asn-190, MOD:00684." [IEDB_epitope:1775776, IEDB_epitope:1775777, IEDB_epitope:1775778, PRO:DNx]

organism-gene


PR:P25911
tyrosine-protein kinase Lyn (mouse)
mLYN
"A tyrosine-protein kinase Lyn that is encoded in the genome of mouse." [OMA:P25911, PRO:DNx]

organism-sequence


PR:P25911-1
tyrosine-protein kinase Lyn isoform 1 (mouse)
mLYN/iso:1
"A tyrosine-protein kinase Lyn isoform 1 that is encoded in the genome of mouse." [PRO:DNx]

organism-sequence


PR:P25911-2
tyrosine-protein kinase Lyn isoform 2 (mouse)
mLYN/iso:2
"A tyrosine-protein kinase Lyn isoform 2 that is encoded in the genome of mouse." [PRO:DNx]

organism-gene


PR:Q07014
tyrosine-protein kinase Lyn (rat)
rLYN
"A tyrosine-protein kinase Lyn that is encoded in the genome of rat." [OMA:Q07014, PRO:DNx]

organism-sequence


PR:Q07014-1
tyrosine-protein kinase Lyn isoform LYN A (rat)
rLYN/iso:LYN A
"A tyrosine-protein kinase Lyn isoform 1 that is encoded in the genome of rat." [PRO:DNx]

organism-sequence


PR:Q07014-2
tyrosine-protein kinase Lyn isoform LYN B (rat)
rLYN/iso:LYN B
"A tyrosine-protein kinase Lyn isoform 2 that is encoded in the genome of rat." [PRO:DNx]

sequence


PR:000038724
tyrosine-protein kinase Lyn isoform 1
LYN/iso:1
"A tyrosine-protein kinase Lyn that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P07948-1 or a 1:1 ortholog thereof." [PRO:DNx]

organism-sequence


PR:P07948-1
tyrosine-protein kinase Lyn isoform 1 (human)
hLYN/iso:1
"A tyrosine-protein kinase Lyn isoform 1 that is encoded in the genome of human." [PRO:DNx]

organism-sequence


PR:P25911-1
tyrosine-protein kinase Lyn isoform 1 (mouse)
mLYN/iso:1
"A tyrosine-protein kinase Lyn isoform 1 that is encoded in the genome of mouse." [PRO:DNx]

organism-sequence


PR:Q07014-1
tyrosine-protein kinase Lyn isoform LYN A (rat)
rLYN/iso:LYN A
"A tyrosine-protein kinase Lyn isoform 1 that is encoded in the genome of rat." [PRO:DNx]

sequence


PR:000038725
tyrosine-protein kinase Lyn isoform 2
LYN/iso:2
"A tyrosine-protein kinase Lyn that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P07948-2 or a 1:1 ortholog thereof." [PRO:DNx]

organism-sequence


PR:P07948-2
tyrosine-protein kinase Lyn isoform 2 (human)
hLYN/iso:2
"A tyrosine-protein kinase Lyn isoform 2 that is encoded in the genome of human." [PRO:DNx]

organism-sequence


PR:P25911-2
tyrosine-protein kinase Lyn isoform 2 (mouse)
mLYN/iso:2
"A tyrosine-protein kinase Lyn isoform 2 that is encoded in the genome of mouse." [PRO:DNx]

organism-sequence


PR:Q07014-2
tyrosine-protein kinase Lyn isoform LYN B (rat)
rLYN/iso:LYN B
"A tyrosine-protein kinase Lyn isoform 2 that is encoded in the genome of rat." [PRO:DNx]