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gene
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 PR:000010125 |
   dual specificity mitogen-activated protein kinase kinase 1
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   MAP2K1
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  "A protein that is a translation product of the human MAP2K1 gene or a 1:1 ortholog thereof." [PRO:DNx]
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organism-gene
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 PR:P29678 |
   dual specificity mitogen-activated protein kinase kinase 1 (rabbit)
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   rabbit-MAP2K1
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  "A dual specificity mitogen-activated protein kinase kinase 1 that is encoded in the genome of rabbit." [OMA:P29678, PRO:DNx]
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organism-gene
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|
 PR:P31938 |
   dual specificity mitogen-activated protein kinase kinase 1 (mouse)
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   mMAP2K1
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  "A dual specificity mitogen-activated protein kinase kinase 1 that is encoded in the genome of mouse." [OMA:P31938, PRO:DNx]
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organism-sequence
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|
 PR:P31938-1 |
   dual specificity mitogen-activated protein kinase kinase 1 isoform 1 (mouse)
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   mMAP2K1/iso:1
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  "A dual specificity mitogen-activated protein kinase kinase 1 isoform 1 that is encoded in the genome of mouse." [PRO:CNx]
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organism-gene
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|
 PR:Q01986 |
   dual specificity mitogen-activated protein kinase kinase 1 (rat)
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   rMAP2K1
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  "A dual specificity mitogen-activated protein kinase kinase 1 that is encoded in the genome of rat." [OMA:Q01986, PRO:DNx]
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organism-gene
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|
 PR:Q02750 |
   dual specificity mitogen-activated protein kinase kinase 1 (human)
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   hMAP2K1
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  "A dual specificity mitogen-activated protein kinase kinase 1 that is encoded in the genome of human." [PRO:DNx, UniProtKB:Q02750]
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organism-sequence
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|
 PR:Q02750-1 |
   dual specificity mitogen-activated protein kinase kinase 1 isoform 1 (human)
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   hMAP2K1/iso:1
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  "A dual specificity mitogen-activated protein kinase kinase 1 isoform 1 that is encoded in the genome of human." [PRO:CNx]
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organism-modification
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|
 PR:000026220 |
   dual specificity mitogen-activated protein kinase kinase 1 isoform 1 phosphorylated 1 (human)
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   hMAP2K1/iso:1/Phos:1
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  "A dual specificity mitogen-activated protein kinase kinase 1 isoform 1 phosphorylated 1 in human. UniProtKB:Q02750-1, Ser-218/Ser-222, MOD:00046." [PMID:8131746, PRO:CNA]
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organism-sequence
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|
 PR:Q02750-2 |
   dual specificity mitogen-activated protein kinase kinase 1 isoform h2 (human)
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   hMAP2K1/iso:h2
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  "A dual specificity mitogen-activated protein kinase kinase 1 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q02750-2." [PRO:DNx, UniProtKB:Q02750]
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organism-modification
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|
 PR:000045873 |
   dual specificity mitogen-activated protein kinase kinase 1 phosphorylated 1 (human)
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   hMAP2K1/Phos:1
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  "A dual specificity mitogen-activated protein kinase kinase 1 (human) that has been phosphorylated on the residue at the position equivalent to Ser-298 of the amino acid sequence represented by UniProtKB:Q02750-1. Example: UniProtKB:Q02750-1, Ser-298, MOD:00046." [iPTMnet:Q02750, PMID:11948406, PMID:18593598]
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organism-modification
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 PR:000048292 |
   dual specificity mitogen-activated protein kinase kinase 1, initiator methionine removed phosphorylated 1 (human)
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   hMAP2K1/InitMet-/Phos:1
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  "A dual specificity mitogen-activated protein kinase kinase 1 (human) that has had the initiator methionine removed and has been post-translationally modified to include phosphoserine at positions 218 and 222 of the amino acid sequence represented by UniProtKB:Q02750. UniProtKB:Q02750, 2-393, Ser-218/Ser-222, MOD:00046." [PRO:DNx, Reactome:R-HSA-109837]
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organism-modification
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|
 PR:000048293 |
   dual specificity mitogen-activated protein kinase kinase 1, initiator methionine removed phosphorylated 2 (human)
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   hMAP2K1/InitMet-/Phos:2
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  "A dual specificity mitogen-activated protein kinase kinase 1 (human) that has had the initiator methionine removed and has been post-translationally modified to include phosphoserine at positions 218 and 222, and phosphothreonine at positions 286 and 292 of the amino acid sequence represented by UniProtKB:Q02750. UniProtKB:Q02750, 2-393, Ser-218/Ser-222, MOD:00046|Thr-286/Thr-292, MOD:00047." [PRO:DNx, Reactome:R-HSA-112339]
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organism-modification
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|
 PR:000048294 |
   dual specificity mitogen-activated protein kinase kinase 1, initiator methionine removed phosphorylated 3 (human)
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   hMAP2K1/InitMet-/Phos:3
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  "A dual specificity mitogen-activated protein kinase kinase 1 (human) that has had the initiator methionine removed and has been post-translationally modified to include phosphoserine at positions 218 and 222, and phosphothreonine at position 292 of the amino acid sequence represented by UniProtKB:Q02750. UniProtKB:Q02750, 2-393, Ser-218/Ser-222, MOD:00046|Thr-292, MOD:00047." [PRO:DNx, Reactome:R-HSA-5674490]
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organism-modification
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 PR:000048295 |
   dual specificity mitogen-activated protein kinase kinase 1, initiator methionine removed phosphorylated 4 (human)
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   hMAP2K1/InitMet-/Phos:4
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  "A dual specificity mitogen-activated protein kinase kinase 1 (human) that has had the initiator methionine removed and has been post-translationally modified to include phosphothreonine at positions 286 and 292 of the amino acid sequence represented by UniProtKB:Q02750. UniProtKB:Q02750, 2-393, Thr-286/Thr-292, MOD:00047." [PRO:DNx, Reactome:R-HSA-112374]
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organism-modification
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|
 PR:000060664 |
   dual specificity mitogen-activated protein kinase kinase 1 sequence variant Q56P, initiator methionine removed form (human)
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   hMAP2K1/var:Q56P/InitMet-
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  "A dual specificity mitogen-activated protein kinase kinase 1 (human) that has a Pro residue at the position equivalent to Gln-56 of the amino acid sequence represented by UniProtKB:Q02750-1 and that has had the initiator methionine removed. Example: UniProtKB:Q02750-1, 2-393, Gln-56, CHEBI:50342." [PRO:DNx, Reactome:R-HSA-9652064]
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organism-modification
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|
 PR:000061077 |
   dual specificity mitogen-activated protein kinase kinase 1 sequence variant D67N, initiator methionine removed form (human)
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   hMAP2K1/var:D67N/InitMet-
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  "A dual specificity mitogen-activated protein kinase kinase 1 (human) that has an Asn residue at the position equivalent to Asp-67 of the amino acid sequence represented by UniProtKB:Q02750-1 and that has had the initiator methionine removed. Example: UniProtKB:Q02750-1, 2-393, Asp-67, CHEBI:50347." [PRO:DNx, Reactome:R-HSA-9652016]
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organism-modification
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|
 PR:000061139 |
   dual specificity mitogen-activated protein kinase kinase 1 sequence variant C121S, initiator methionine removed form (human)
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   hMAP2K1/var:C121S/InitMet-
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  "A dual specificity mitogen-activated protein kinase kinase 1 (human) that has a Ser residue at the position equivalent to Cys-121 of the amino acid sequence represented by UniProtKB:Q02750-1 and that has had the initiator methionine removed. Example: UniProtKB:Q02750-1, 2-393, Cys-121, CHEBI:29999." [PRO:DNx, Reactome:R-HSA-9652013]
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organism-modification
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|
 PR:000061271 |
   dual specificity mitogen-activated protein kinase kinase 1 sequence variant D67Y, initiator methionine removed form (human)
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   hMAP2K1/var:D67Y/InitMet-
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  "A dual specificity mitogen-activated protein kinase kinase 1 (human) that has a Tyr residue at the position equivalent to Asp-67 of the amino acid sequence represented by UniProtKB:Q02750-1 and that has had the initiator methionine removed. Example: UniProtKB:Q02750-1, 2-393, Asp-67, CHEBI:46858." [PRO:DNx, Reactome:R-HSA-9652019]
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organism-modification
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|
 PR:000061444 |
   dual specificity mitogen-activated protein kinase kinase 1 sequence variant F53V, initiator methionine removed form (human)
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   hMAP2K1/var:F53V/InitMet-
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  "A dual specificity mitogen-activated protein kinase kinase 1 (human) that has a Val residue at the position equivalent to Phe-53 of the amino acid sequence represented by UniProtKB:Q02750-1 and that has had the initiator methionine removed. Example: UniProtKB:Q02750-1, 2-393, Phe-53, CHEBI:30015." [PRO:DNx, Reactome:R-HSA-9652038]
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organism-modification
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|
 PR:000061741 |
   dual specificity mitogen-activated protein kinase kinase 1 sequence variant E203K, initiator methionine removed form (human)
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   hMAP2K1/var:E203K/InitMet-
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  "A dual specificity mitogen-activated protein kinase kinase 1 (human) that has a Lys residue at the position equivalent to Glu-203 of the amino acid sequence represented by UniProtKB:Q02750-1 and that has had the initiator methionine removed. Example: UniProtKB:Q02750-1, 2-393, Glu-203, CHEBI:29967." [PRO:DNx, Reactome:R-HSA-9652023]
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organism-modification
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|
 PR:000061927 |
   dual specificity mitogen-activated protein kinase kinase 1 sequence variant G128V, initiator methionine removed form (human)
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   hMAP2K1/var:G128V/InitMet-
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  "A dual specificity mitogen-activated protein kinase kinase 1 (human) that has a Val residue at the position equivalent to Gly-128 of the amino acid sequence represented by UniProtKB:Q02750-1 and that has had the initiator methionine removed. Example: UniProtKB:Q02750-1, 2-393, Gly-128, CHEBI:30015." [PRO:DNx, Reactome:R-HSA-9652047]
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organism-modification
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|
 PR:000062169 |
   dual specificity mitogen-activated protein kinase kinase 1 sequence variant F53Y, initiator methionine removed form (human)
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   hMAP2K1/var:F53Y/InitMet-
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  "A dual specificity mitogen-activated protein kinase kinase 1 (human) that has a Tyr residue at the position equivalent to Phe-53 of the amino acid sequence represented by UniProtKB:Q02750-1 and that has had the initiator methionine removed. Example: UniProtKB:Q02750-1, 2-393, Phe-53, CHEBI:46858." [PRO:DNx, Reactome:R-HSA-9652041]
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organism-modification
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|
 PR:000062375 |
   dual specificity mitogen-activated protein kinase kinase 1 sequence variant K57N, initiator methionine removed form (human)
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   hMAP2K1/var:K57N/InitMet-
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  "A dual specificity mitogen-activated protein kinase kinase 1 (human) that has an Asn residue at the position equivalent to Lys-57 of the amino acid sequence represented by UniProtKB:Q02750-1 and that has had the initiator methionine removed. Example: UniProtKB:Q02750-1, 2-393, Lys-57, CHEBI:50347." [PRO:DNx, Reactome:R-HSA-9652050]
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organism-modification
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|
 PR:000062727 |
   dual specificity mitogen-activated protein kinase kinase 1 sequence variant P124L, initiator methionine removed form (human)
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   hMAP2K1/var:P124L/InitMet-
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  "A dual specificity mitogen-activated protein kinase kinase 1 (human) that has a Leu residue at the position equivalent to Pro-124 of the amino acid sequence represented by UniProtKB:Q02750-1 and that has had the initiator methionine removed. Example: UniProtKB:Q02750-1, 2-393, Pro-124, CHEBI:30006." [PRO:DNx, Reactome:R-HSA-9652056]
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organism-modification
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|
 PR:000062811 |
   dual specificity mitogen-activated protein kinase kinase 1 sequence variant K57T, initiator methionine removed form (human)
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   hMAP2K1/var:K57T/InitMet-
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  "A dual specificity mitogen-activated protein kinase kinase 1 (human) that has a Thr residue at the position equivalent to Lys-57 of the amino acid sequence represented by UniProtKB:Q02750-1 and that has had the initiator methionine removed. Example: UniProtKB:Q02750-1, 2-393, Lys-57, CHEBI:30013." [PRO:DNx, Reactome:R-HSA-9652052]
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organism-modification
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 PR:000062854 |
   dual specificity mitogen-activated protein kinase kinase 1 sequence variant V60E, initiator methionine removed form (human)
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   hMAP2K1/var:V60E/InitMet-
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  "A dual specificity mitogen-activated protein kinase kinase 1 (human) that has a Glu residue at the position equivalent to Val-60 of the amino acid sequence represented by UniProtKB:Q02750-1 and that has had the initiator methionine removed. Example: UniProtKB:Q02750-1, 2-393, Val-60, CHEBI:29972." [PRO:DNx, Reactome:R-HSA-9652067]
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organism-modification
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 PR:000063158 |
   dual specificity mitogen-activated protein kinase kinase 1 sequence variant P124Q, initiator methionine removed form (human)
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   hMAP2K1/var:P124Q/InitMet-
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  "A dual specificity mitogen-activated protein kinase kinase 1 (human) that has a Gln residue at the position equivalent to Pro-124 of the amino acid sequence represented by UniProtKB:Q02750-1 and that has had the initiator methionine removed. Example: UniProtKB:Q02750-1, 2-393, Pro-124, CHEBI:30011." [PRO:DNx, Reactome:R-HSA-9652058]
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organism-modification
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 PR:000063546 |
   dual specificity mitogen-activated protein kinase kinase 1 sequence variant F53L, initiator methionine removed form (human)
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   hMAP2K1/var:F53L/InitMet-
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  "A dual specificity mitogen-activated protein kinase kinase 1 (human) that has a Leu residue at the position equivalent to Phe-53 of the amino acid sequence represented by UniProtKB:Q02750-1 and that has had the initiator methionine removed. Example: UniProtKB:Q02750-1, 2-393, Phe-53, CHEBI:30006." [PRO:DNx, Reactome:R-HSA-9652031]
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organism-modification
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|
 PR:000063595 |
   dual specificity mitogen-activated protein kinase kinase 1 sequence variant F53S, initiator methionine removed form (human)
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   hMAP2K1/var:F53S/InitMet-
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  "A dual specificity mitogen-activated protein kinase kinase 1 (human) that has a Ser residue at the position equivalent to Phe-53 of the amino acid sequence represented by UniProtKB:Q02750-1 and that has had the initiator methionine removed. Example: UniProtKB:Q02750-1, 2-393, Phe-53, CHEBI:29999." [PRO:DNx, Reactome:R-HSA-9652034]
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organism-modification
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|
 PR:000063606 |
   dual specificity mitogen-activated protein kinase kinase 1 sequence variant G128D, initiator methionine removed form (human)
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   hMAP2K1/var:G128D/InitMet-
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  "A dual specificity mitogen-activated protein kinase kinase 1 (human) that has an Asp residue at the position equivalent to Gly-128 of the amino acid sequence represented by UniProtKB:Q02750-1 and that has had the initiator methionine removed. Example: UniProtKB:Q02750-1, 2-393, Gly-128, CHEBI:29958." [PRO:DNx, Reactome:R-HSA-9652043]
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organism-modification
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|
 PR:000063710 |
   dual specificity mitogen-activated protein kinase kinase 1 sequence variant Y130C, initiator methionine removed form (human)
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   hMAP2K1/var:Y130C/InitMet-
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  "A dual specificity mitogen-activated protein kinase kinase 1 (human) that has a Cys residue at the position equivalent to Tyr-130 of the amino acid sequence represented by UniProtKB:Q02750-1 and that has had the initiator methionine removed. Example: UniProtKB:Q02750-1, 2-393, Tyr-130, CHEBI:29950." [PRO:DNx, Reactome:R-HSA-9652101]
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organism-modification
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|
 PR:000064073 |
   dual specificity mitogen-activated protein kinase kinase 1 sequence variant F53C, initiator methionine removed form (human)
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   hMAP2K1/var:F53C/InitMet-
 |
  "A dual specificity mitogen-activated protein kinase kinase 1 (human) that has a Cys residue at the position equivalent to Phe-53 of the amino acid sequence represented by UniProtKB:Q02750-1 and that has had the initiator methionine removed. Example: UniProtKB:Q02750-1, 2-393, Phe-53, CHEBI:29950." [PRO:DNx, Reactome:R-HSA-9652028]
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organism-modification
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|
 PR:000064213 |
   dual specificity mitogen-activated protein kinase kinase 1 sequence variant P124S, initiator methionine removed form (human)
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   hMAP2K1/var:P124S/InitMet-
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  "A dual specificity mitogen-activated protein kinase kinase 1 (human) that has a Ser residue at the position equivalent to Pro-124 of the amino acid sequence represented by UniProtKB:Q02750-1 and that has had the initiator methionine removed. Example: UniProtKB:Q02750-1, 2-393, Pro-124, CHEBI:29999." [PRO:DNx, Reactome:R-HSA-9652062]
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organism-modification
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|
 PR:000077881 |
   dual specificity mitogen-activated protein kinase kinase 1 deaminated 1 (human)
 |
   hMAP2K1/Deam:1
 |
  "A dual specificity mitogen-activated protein kinase kinase 1 (human) that has been deaminated on the residue at the position equivalent to Gln-354 of the amino acid sequence represented by UniProtKB:Q02750-1. Example: UniProtKB:Q02750-1, Gln-354, MOD:00685." [IEDB_epitope:1779907, PRO:DNx]
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sequence
 |


|
 PR:000026194 |
   dual specificity mitogen-activated protein kinase kinase 1 isoform 1
 |
   MAP2K1/iso:1
 |
  "A dual specificity mitogen-activated protein kinase kinase 1 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q02750-1 or a 1:1 ortholog thereof." [PRO:CNx]
 |

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organism-sequence
 |


|
 PR:P31938-1 |
   dual specificity mitogen-activated protein kinase kinase 1 isoform 1 (mouse)
 |
   mMAP2K1/iso:1
 |
  "A dual specificity mitogen-activated protein kinase kinase 1 isoform 1 that is encoded in the genome of mouse." [PRO:CNx]
 |

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organism-sequence
 |


|
 PR:Q02750-1 |
   dual specificity mitogen-activated protein kinase kinase 1 isoform 1 (human)
 |
   hMAP2K1/iso:1
 |
  "A dual specificity mitogen-activated protein kinase kinase 1 isoform 1 that is encoded in the genome of human." [PRO:CNx]
 |

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organism-modification
 |


|
 PR:000026220 |
   dual specificity mitogen-activated protein kinase kinase 1 isoform 1 phosphorylated 1 (human)
 |
   hMAP2K1/iso:1/Phos:1
 |
  "A dual specificity mitogen-activated protein kinase kinase 1 isoform 1 phosphorylated 1 in human. UniProtKB:Q02750-1, Ser-218/Ser-222, MOD:00046." [PMID:8131746, PRO:CNA]
 |

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modification
 |


|
 PR:000026196 |
   dual specificity mitogen-activated protein kinase kinase 1 isoform 1 phosphorylated 1
 |
   MAP2K1/iso:1/Phos:1
 |
  "A dual specificity mitogen-activated protein kinase kinase 1 isoform 1 that has been phosphorylated in the two conserved Ser residues involved in kinase activation. Example: UniProtKB:Q02750-1, Ser-218/Ser-222, MOD:00046." [PMID:8131746, PRO:CNA]
 |

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organism-modification
 |


|
 PR:000026220 |
   dual specificity mitogen-activated protein kinase kinase 1 isoform 1 phosphorylated 1 (human)
 |
   hMAP2K1/iso:1/Phos:1
 |
  "A dual specificity mitogen-activated protein kinase kinase 1 isoform 1 phosphorylated 1 in human. UniProtKB:Q02750-1, Ser-218/Ser-222, MOD:00046." [PMID:8131746, PRO:CNA]
 |

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