back to PRO homepage
  Home |   Linked Open Data |   Browse |  
Search

|   Statistics |   Download
 RACE-PRO
 PRO tracker
 Community
 PRO Consortium
 Publications
 Documentation

Protein Ontology report - mediator of RNA polymerase II transcription subunit 8
PR:000010307 - http://purl.obolibrary.org/obo/PR_000010307
 
  Protein Forms  Complex  Annotations      
Ontology Information Show OBO stanza
  PRO ID
PR:000010307   
  PRO namemediator of RNA polymerase II transcription subunit 8 
  Synonyms
PRO-Short-label: EXACT:MED8
Other: EXACT:activator-recruited cofactor 32 kDa component | ARC32 | mediator complex subunit 8
  Definition"A protein that is a translation product of the human MED8 gene or a 1:1 ortholog thereof." [PRO:DNx] 
  PRO Categorygene 
  ParentPR:000000001 protein
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Gene1                                                  Organism-Gene 5                                        
         Sequence1                                                  Organism-Sequence 6                                        
         Modification0                                                  Organism-Modification 1                                        
  Term Hierarchy
  Visualization
DAG: OLS:
Back to top
Protein Forms Switch to Compact View   

Category  

PRO ID

Name

Short Name

Definition

Ann. Has Annotation?

Comp. In Complex?
gene



PR:000010307

mediator of RNA polymerase II transcription subunit 8

MED8


"A protein that is a translation product of the human MED8 gene or a 1:1 ortholog thereof." [PRO:DNx]


organism-gene



PR:A1ZBT5

mediator of RNA polymerase II transcription subunit 8 (fruit fly)

fly-MED8


"A mediator of RNA polymerase II transcription subunit 8 that is encoded in the genome of fruit fly." [OMA:A1ZBT5, PRO:DNx]


organism-gene



PR:Q6NYT1

mediator of RNA polymerase II transcription subunit 8 (zebrafish)

z-MED8


"A mediator of RNA polymerase II transcription subunit 8 that is encoded in the genome of zebrafish." [PANTHER:PTHR13074:SF3, PRO:DNx]


organism-gene



PR:Q96G25

mediator of RNA polymerase II transcription subunit 8 (human)

hMED8


"A mediator of RNA polymerase II transcription subunit 8 that is encoded in the genome of human." [PRO:DNx, UniProtKB:Q96G25]


organism-sequence



PR:Q96G25-1

mediator of RNA polymerase II transcription subunit 8 isoform 1 (human)

hMED8/iso:1


"A mediator of RNA polymerase II transcription subunit 8 isoform 1 that is encoded in the genome of human." [PRO:HJD]


organism-sequence



PR:Q96G25-2

mediator of RNA polymerase II transcription subunit 8 isoform h2 (human)

hMED8/iso:h2


"A mediator of RNA polymerase II transcription subunit 8 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q96G25-2." [PRO:DNx, UniProtKB:Q96G25]


organism-sequence



PR:Q96G25-3

mediator of RNA polymerase II transcription subunit 8 isoform h3 (human)

hMED8/iso:h3


"A mediator of RNA polymerase II transcription subunit 8 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q96G25-3." [PRO:DNx, UniProtKB:Q96G25]


organism-modification



PR:000072167

mediator of RNA polymerase II transcription subunit 8 methylated 1 (human)

hMED8/Me:1


"A mediator of RNA polymerase II transcription subunit 8 (human) that has been methylated on the residue at the position equivalent to Cys-31 of the amino acid sequence represented by UniProtKB:Q96G25-1. Example: UniProtKB:Q96G25-1, Cys-31, MOD:00660." [IEDB_epitope:1036206, IEDB_epitope:1049823, PRO:DNx]


organism-gene



PR:Q9D7W5

mediator of RNA polymerase II transcription subunit 8 (mouse)

mMED8


"A mediator of RNA polymerase II transcription subunit 8 that is encoded in the genome of mouse." [OMA:Q9D7W5, PRO:DNx]


organism-sequence



PR:Q9D7W5-1

mediator of RNA polymerase II transcription subunit 8 isoform 1 (mouse)

mMED8/iso:1


"A mediator of RNA polymerase II transcription subunit 8 isoform 1 that is encoded in the genome of mouse." [PMID:16141072, PRO:HJD]

Yes

Yes
organism-gene



PR:Q9U1W2

mediator of RNA polymerase II transcription subunit 8 (worm)

MED8 (worm)


"A mediator of RNA polymerase II transcription subunit 8 that is encoded in the genome of worm." [OMA:Q9U1W2, PRO:DNx]


organism-sequence



PR:Q9U1W2-1

mediator of RNA polymerase II transcription subunit 8 isoform b (worm)

MED8/iso:b (worm)


"A mediator of RNA polymerase II transcription subunit 8 (worm) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9U1W2-1." [PRO:DNx, UniProtKB:Q9U1W2]


organism-sequence



PR:Q9U1W2-2

mediator of RNA polymerase II transcription subunit 8 isoform a (worm)

MED8/iso:a (worm)


"A mediator of RNA polymerase II transcription subunit 8 (worm) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9U1W2-2." [PRO:DNx, UniProtKB:Q9U1W2]


sequence



PR:000028900

mediator of RNA polymerase II transcription subunit 8 isoform 1

MED8/iso:1


"A mediator of RNA polymerase II transcription subunit 8 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9D7W5-1 or a 1:1 ortholog thereof." [PMID:16141072, PRO:HJD]


organism-sequence



PR:Q96G25-1

mediator of RNA polymerase II transcription subunit 8 isoform 1 (human)

hMED8/iso:1


"A mediator of RNA polymerase II transcription subunit 8 isoform 1 that is encoded in the genome of human." [PRO:HJD]


organism-sequence



PR:Q9D7W5-1

mediator of RNA polymerase II transcription subunit 8 isoform 1 (mouse)

mMED8/iso:1


"A mediator of RNA polymerase II transcription subunit 8 isoform 1 that is encoded in the genome of mouse." [PMID:16141072, PRO:HJD]

Yes

Yes
Back to top
MED8 forms found in complexes   

MED8 Component
Complexes
PR:Q9D7W5ZDASHZ1 mMED8/iso:1 PR:000028902 mediator complex, MED26-containing (mouse)
PR:000028957 mediator complex, CDK8-containing (mouse)
Back to top
Functional Annotation (PRO-centric view) Switch to GO Centric View   
PRO Term GO Annotation Evidence
PR:Q9D7W5-1 mMED8/iso:1 located_inGO:0016592 mediator complex MGI_ref:4462751; PMID:20508642