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Protein Ontology report - neurogenic locus notch homolog protein 3
PR:000011334 - http://purl.obolibrary.org/obo/PR_000011334
 
  Protein Forms      
Ontology Information Show OBO stanza
  PRO ID
PR:000011334   
  PRO nameneurogenic locus notch homolog protein 3 
  Synonyms
PRO-Short-label: EXACT:NOTCH3
Other: EXACT:neurogenic locus notch protein 3 | notch 3
  Definition"A NOTCH protein that is a translation product of the human NOTCH3 gene or a 1:1 ortholog thereof." [PRO:DNx] 
  PRO Categorygene 
  ParentPR:000050044 NOTCH protein
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Gene1                                                  Organism-Gene 3                                        
         Sequence0                                                  Organism-Sequence 0                                        
         Modification1                                                  Organism-Modification 4                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Related Cross References

  Db identifiers
IUPHARobj:2860
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Protein Forms Switch to Compact View   

Category  

PRO ID

Name

Short Name

Definition

Ann. Has Annotation?

Comp. In Complex?
gene



PR:000011334

neurogenic locus notch homolog protein 3

NOTCH3


"A NOTCH protein that is a translation product of the human NOTCH3 gene or a 1:1 ortholog thereof." [PRO:DNx]


organism-gene



PR:Q61982

neurogenic locus notch homolog protein 3 (mouse)

mNOTCH3


"A neurogenic locus notch homolog protein 3 that is encoded in the genome of mouse." [OMA:Q61982, PRO:DNx]


organism-modification



PR:000085750

notch 3 intracellular domain (mouse)

mNOTCH3/NICD


"A neurogenic locus notch homolog protein 3 (mouse) that corresponds to the C-terminal portion after proteolytic cleavage by PSEN1 or PSEN2. UniProtKB:Q61982, 1663-2318." [PRO:DAN, UniProtKB:Q61982]


organism-gene



PR:Q9R172

neurogenic locus notch homolog protein 3 (rat)

rNOTCH3


"A neurogenic locus notch homolog protein 3 that is encoded in the genome of rat." [OMA:Q9R172, PRO:DNx]


organism-gene



PR:Q9UM47

neurogenic locus notch homolog protein 3 (human)

hNOTCH3


"A neurogenic locus notch homolog protein 3 that is encoded in the genome of human." [PRO:CNx, UniProtKB:Q9UM47]


organism-modification



PR:000048624

neurogenic locus notch homolog protein 3, signal peptide removed form (human)

hNOTCH3/SigPep-


"A neurogenic locus notch homolog protein 3 (human) that has had the signal peptide removed. UniProtKB:Q9UM47, 40-2321." [PRO:DNx, Reactome:R-HSA-157102]


organism-modification



PR:000063198

neurogenic locus notch homolog protein 3, signal peptide removed O-glycosylated 1 (human)

hNOTCH3/SigPep-/OGlyco:1


"A neurogenic locus notch homolog protein 3 (human) that has had the signal peptide removed and that has been O-glycosylated on the residues at the positions equivalent to Thr-173, Thr-211, Thr-250, Thr-290, Thr-328, Thr-445, Ser-671, Thr-748, Ser-863, Thr-938, Thr-1098, Ser-1136, Thr-1181, and Ser-1349 of the amino acid sequence represented by UniProtKB:Q9UM47. UniProtKB:Q9UM47, 40-2321, Thr-173/Thr-211/Thr-250/Thr-290/Thr-328/Thr-445/Thr-748/Thr-938/Thr-1098/Thr-1181, MOD:00813|Ser-671/Ser-863/Ser-1136/Ser-1349, MOD:00812." [PRO:DNx, Reactome:R-HSA-1467382]


organism-modification



PR:000085917

neurogenic locus notch homolog protein 3, signal peptide removed O-glycosylated 2 (human)

hNOTCH3/SigPep-/OGlyco:2


"A neurogenic locus notch homolog protein 3 (human) that has had the signal peptide removed and that has been O-glycosylated on the residues at the positions equivalent to Ser-84, Ser-125, Thr-173, Thr-211, Thr-250, Thr-290, Thr-328, Ser-357, Ser-437, Thr-445, Ser-475, Ser-513, Ser-588, Ser-626, Ser-663, Ser-671, Ser-740, Thr-748, Ser-863, Ser-893, Thr-938, Ser-968, Thr-1098, Ser-1128, Ser-1136, Thr-1181, Ser-1252, and Ser-1349 of the amino acid sequence represented by UniProtKB:Q9UM47. UniProtKB:Q9UM47, 40-2321, Ser-84/Ser-125/Ser-357/Ser-437/Ser-475/Ser-513/Ser-588/Ser-626/Ser-663/Ser-740/Ser-893/Ser-968/Ser-1128/Ser-1252, MOD:00804|Thr-173/Thr-211/Thr-250/Thr-290/Thr-328/Thr-445/Thr-748/Thr-938/Thr-1098/Thr-1181, MOD:00813|Ser-671/Ser-863/Ser-1136/Ser-1349, MOD:00812." [PRO:DNx, Reactome:R-HSA-1467307, Reactome:R-HSA-1472871]


modification



PR:000020765

neurogenic locus notch homolog protein 3 proteolytic cleavage product

NOTCH3/ClvPrd


"A neurogenic locus notch homolog protein 3 that has been processed by proteolytic cleavage." [PRO:DNx]


organism-modification



PR:000085750

notch 3 intracellular domain (mouse)

mNOTCH3/NICD


"A neurogenic locus notch homolog protein 3 (mouse) that corresponds to the C-terminal portion after proteolytic cleavage by PSEN1 or PSEN2. UniProtKB:Q61982, 1663-2318." [PRO:DAN, UniProtKB:Q61982]