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Protein Ontology report - noelin
PR:000011623 - http://purl.obolibrary.org/obo/PR_000011623
 
  Protein Forms  Annotations      
Ontology Information Show OBO stanza
  PRO ID
PR:000011623   
  PRO namenoelin 
  Synonyms
PRO-Short-label: EXACT:OLFM1
Gene-based: RELATED:NOE1 | Noel | NOEL1
Other: EXACT:neuronal olfactomedin-related ER localized protein | olfactomedin-1 | pancortin
  Definition"A protein that is a translation product of the human OLFM1 gene or a 1:1 ortholog thereof." [PRO:DNx] 
  PRO Categorygene 
  ParentPR:000000001 protein
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Gene1                                                  Organism-Gene 4                                        
         Sequence4                                                  Organism-Sequence 15                                        
         Modification0                                                  Organism-Modification 3                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Protein Forms Switch to Compact View   

Category  

PRO ID

Name

Short Name

Definition

Ann. Has Annotation?

Comp. In Complex?
gene



PR:000011623

noelin

OLFM1


"A protein that is a translation product of the human OLFM1 gene or a 1:1 ortholog thereof." [PRO:DNx]


organism-gene



PR:O88998

noelin (mouse)

mOLFM1


"A noelin that is encoded in the genome of mouse." [OMA:O88998, PRO:DNx]


organism-sequence



PR:O88998-1

noelin isoform 1 (mouse)

mOLFM1/iso:1


"A noelin isoform 1 that is encoded in the genome of mouse." [PMID:22992957, PMID:9473566, PRO:HJD]

Yes

organism-sequence



PR:O88998-2

noelin isoform 2 (mouse)

mOLFM1/iso:2


"A noelin isoform 2 that is encoded in the genome of mouse. This isoform has Gly at position 153, and the C-terminal region 154-485 is missing." [PMID:22992957, PRO:HJD, RefSeq:NM_001038612]

Yes

organism-sequence



PR:O88998-3

noelin isoform 3 (mouse)

mOLFM1/iso:3


"A noelin isoform 3 that is encoded in the genome of mouse. This isoform has a shorter N terminus." [PMID:22992957, PRO:HJD, RefSeq:NM_001038613]

Yes

organism-sequence



PR:O88998-4

noelin isoform 4 (mouse)

mOLFM1/iso:4


"A noelin isoform 4 that is encoded in the genome of mouse. This isoform has a shorter N terminus, a Gly at position 153, and the C-terminal region 154-485 is missing." [PMID:16141072, PMID:22992957, PRO:HJD]

Yes

organism-gene



PR:Q62609

noelin (rat)

rOLFM1


"A noelin that is encoded in the genome of rat." [OMA:Q62609, PRO:DNx]


organism-sequence



PR:Q62609-1

noelin isoform r1 (rat)

rOLFM1/iso:r1


"A noelin (rat) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q62609-1." [PRO:DNx, UniProtKB:Q62609]


organism-sequence



PR:Q62609-2

noelin isoform r2 (rat)

rOLFM1/iso:r2


"A noelin (rat) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q62609-2." [PRO:DNx, UniProtKB:Q62609]


organism-sequence



PR:Q62609-3

noelin isoform r3 (rat)

rOLFM1/iso:r3


"A noelin (rat) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q62609-3." [PRO:DNx, UniProtKB:Q62609]


organism-sequence



PR:Q62609-4

noelin isoform r4 (rat)

rOLFM1/iso:r4


"A noelin (rat) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q62609-4." [PRO:DNx, UniProtKB:Q62609]


organism-modification



PR:000059217

noelin N-glycosylated 1 (rat)

rOLFM1/NGlyco:1


"A noelin (rat) that has been N-glycosylated at the residue equivalent to Asn-103 of the amino acid sequence represented by UniProtKB:Q62609-1, in which the glycan structure is represented by GlyTouCan:G30159WR. Example: UniProtKB:Q62609-1, Asn-103, MOD:00160~GNO:G30159WR." [GlyGen:Q62609-1, PMID:24090084, PRO:DNx]


organism-modification



PR:000059218

noelin N-glycosylated 2 (rat)

rOLFM1/NGlyco:2


"A noelin (rat) that has been N-glycosylated at the residue equivalent to Asn-103 of the amino acid sequence represented by UniProtKB:Q62609-1, in which the glycan composition is represented by GlyTouCan:G88725PI. Example: UniProtKB:Q62609-1, Asn-103, MOD:00160~GNO:G88725PI." [GlyGen:Q62609-1, PMID:24090084, PRO:DNx]


organism-gene



PR:Q99784

noelin (human)

hOLFM1


"A noelin that is encoded in the genome of human." [PRO:DNx, UniProtKB:Q99784]


organism-sequence



PR:Q99784-1

noelin isoform 1 (human)

hOLFM1/iso:1


"A noelin isoform 1 that is encoded in the genome of human." [PRO:CNA]


organism-sequence



PR:Q99784-2

noelin isoform 2 (human)

hOLFM1/iso:2


"A noelin isoform 2 that is encoded in the genome of human." [PRO:CNA]


organism-sequence



PR:Q99784-3

noelin isoform 3 (human)

hOLFM1/iso:3


"A noelin isoform 3 that is encoded in the genome of human." [PRO:CNA]


organism-sequence



PR:Q99784-4

noelin isoform 4 (human)

hOLFM1/iso:4


"A noelin isoform 4 that is encoded in the genome of human." [PRO:CNA]


organism-sequence



PR:Q99784-5

noelin isoform h5 (human)

hOLFM1/iso:h5


"A noelin (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q99784-5." [PRO:DNx, UniProtKB:Q99784]


organism-modification



PR:000057976

noelin N-glycosylated 1 (human)

hOLFM1/NGlyco:1


"A noelin (human) that has been N-glycosylated at the residue equivalent to Asn-394 of the amino acid sequence represented by UniProtKB:Q99784-1, in which the glycan composition is represented by GlyTouCan:G00912UN. Example: UniProtKB:Q99784-1, Asn-394, MOD:00160~GNO:G00912UN." [GlyGen:Q99784-1, PMID:29671580, PRO:DNx]


organism-gene



PR:Q9IAK4

noelin (chicken)

chick-OLFM1


"A noelin that is encoded in the genome of chicken." [OMA:Q9IAK4, PRO:DNx]


organism-sequence



PR:Q9IAK4-1

noelin isoform 1 (chicken)

chick-OLFM1/iso:1


"A noelin (chicken) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9IAK4-1." [PRO:DNx, UniProtKB:Q9IAK4]


organism-sequence



PR:Q9IAK4-2

noelin isoform 2 (chicken)

chick-OLFM1/iso:2


"A noelin (chicken) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9IAK4-2." [PRO:DNx, UniProtKB:Q9IAK4]


sequence



PR:000037090

noelin isoform 1

OLFM1/iso:1


"A noelin that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:O88998-1 or a 1:1 ortholog thereof." [PRO:CNA]


organism-sequence



PR:O88998-1

noelin isoform 1 (mouse)

mOLFM1/iso:1


"A noelin isoform 1 that is encoded in the genome of mouse." [PMID:22992957, PMID:9473566, PRO:HJD]

Yes

organism-sequence



PR:Q99784-1

noelin isoform 1 (human)

hOLFM1/iso:1


"A noelin isoform 1 that is encoded in the genome of human." [PRO:CNA]


sequence



PR:000037092

noelin isoform 2

OLFM1/iso:2


"A noelin that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:O88998-2 or a 1:1 ortholog thereof." [PMID:22992957, PRO:HJD, RefSeq:NM_001038612]


organism-sequence



PR:O88998-2

noelin isoform 2 (mouse)

mOLFM1/iso:2


"A noelin isoform 2 that is encoded in the genome of mouse. This isoform has Gly at position 153, and the C-terminal region 154-485 is missing." [PMID:22992957, PRO:HJD, RefSeq:NM_001038612]

Yes

organism-sequence



PR:Q99784-2

noelin isoform 2 (human)

hOLFM1/iso:2


"A noelin isoform 2 that is encoded in the genome of human." [PRO:CNA]


sequence



PR:000037094

noelin isoform 3

OLFM1/iso:3


"A noelin that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:O88998-3 or a 1:1 ortholog thereof." [PMID:22992957, PRO:HJD, RefSeq:NM_001038613]


organism-sequence



PR:O88998-3

noelin isoform 3 (mouse)

mOLFM1/iso:3


"A noelin isoform 3 that is encoded in the genome of mouse. This isoform has a shorter N terminus." [PMID:22992957, PRO:HJD, RefSeq:NM_001038613]

Yes

organism-sequence



PR:Q99784-3

noelin isoform 3 (human)

hOLFM1/iso:3


"A noelin isoform 3 that is encoded in the genome of human." [PRO:CNA]


sequence



PR:000037096

noelin isoform 4

OLFM1/iso:4


"A noelin that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:O88998-4 or a 1:1 ortholog thereof." [PMID:16141072, PMID:22992957, PRO:HJD]


organism-sequence



PR:O88998-4

noelin isoform 4 (mouse)

mOLFM1/iso:4


"A noelin isoform 4 that is encoded in the genome of mouse. This isoform has a shorter N terminus, a Gly at position 153, and the C-terminal region 154-485 is missing." [PMID:16141072, PMID:22992957, PRO:HJD]

Yes

organism-sequence



PR:Q99784-4

noelin isoform 4 (human)

hOLFM1/iso:4


"A noelin isoform 4 that is encoded in the genome of human." [PRO:CNA]


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Functional Annotation (PRO-centric view) Switch to GO Centric View   
PRO Term GO Annotation Evidence
PR:O88998-1 mOLFM1/iso:1 acts_upstream_of_or_withinGO:1902003 regulation of amyloid-beta formation MGI_ref:5444053; PMID:22992957
GO:1902430 negative regulation of amyloid-beta formation MGI_ref:5444053; PMID:22992957
enablesGO:0001540 amyloid-beta binding MGI_ref:5444053; PMID:22992957
PR:O88998-2 mOLFM1/iso:2
This isoform has Gly at position 153, and the C-terminal region 154-485 is missing
acts_upstream_of_or_withinGO:1902003 regulation of amyloid-beta formation MGI_ref:5444053; PMID:22992957
GO:2001223 negative regulation of neuron migration MGI_ref:5444053; PMID:22992957
enablesGO:0001540 amyloid-beta binding MGI_ref:5444053; PMID:22992957
PR:O88998-3 mOLFM1/iso:3
This isoform has a shorter N terminus
acts_upstream_of_or_withinGO:0051259 protein complex oligomerization MGI_ref:3611587; PMID:15927402
enablesGO:0001540 amyloid-beta binding MGI_ref:5444053; PMID:22992957
located_inGO:0005615 extracellular space MGI_ref:3611587; PMID:15927402
PR:O88998-4 mOLFM1/iso:4
This isoform has a shorter N terminus, a Gly at position 153, and the C-terminal region 154-485 is missing
acts_upstream_of_or_withinGO:2001223 negative regulation of neuron migration MGI_ref:5444053; PMID:22992957
enablesGO:0001540 amyloid-beta binding MGI_ref:5444053; PMID:22992957
located_inGO:0005615 extracellular space MGI_ref:3611587; PMID:15927402