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Protein Ontology report - bifunctional phosphoribosylaminoimidazole carboxylase/phosphoribosylaminoimidazole succinocarboxamide synthetase
PR:000012235 - http://purl.obolibrary.org/obo/PR_000012235
 
  Protein Forms      
Ontology Information Show OBO stanza
  PRO ID
PR:000012235   
  PRO namebifunctional phosphoribosylaminoimidazole carboxylase/phosphoribosylaminoimidazole succinocarboxamide synthetase 
  Synonyms
PRO-Short-label: EXACT:PAICS
Gene-based: RELATED:ADE2 | AIRC | PAIS
  Definition"A protein that is a translation product of the human PAICS gene or a 1:1 ortholog thereof." [PRO:DNx] 
  PRO Categorygene 
  ParentPR:000000001 protein
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Gene1                                                  Organism-Gene 6                                        
         Sequence1                                                  Organism-Sequence 4                                        
         Modification1                                                  Organism-Modification 12                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Protein Forms Switch to Compact View   

Category  
PRO ID
Name
Short Name
Definition
Ann. Has Annotation?

Comp. In Complex?
gene


PR:000012235
bifunctional phosphoribosylaminoimidazole carboxylase/phosphoribosylaminoimidazole succinocarboxamide synthetase
PAICS
"A protein that is a translation product of the human PAICS gene or a 1:1 ortholog thereof." [PRO:DNx]

organism-gene


PR:P22234
bifunctional phosphoribosylaminoimidazole carboxylase/phosphoribosylaminoimidazole succinocarboxamide synthetase (human)
hPAICS
"A bifunctional phosphoribosylaminoimidazole carboxylase/phosphoribosylaminoimidazole succinocarboxamide synthetase that is encoded in the genome of human." [PRO:DNx, UniProtKB:P22234]

organism-sequence


PR:P22234-1
bifunctional phosphoribosylaminoimidazole carboxylase/phosphoribosylaminoimidazole succinocarboxamide synthetase isoform 1 (human)
hPAICS/iso:1
"A bifunctional phosphoribosylaminoimidazole carboxylase/phosphoribosylaminoimidazole succinocarboxamide synthetase isoform 1 that is encoded in the genome of human." [PRO:DNx]

organism-sequence


PR:P22234-2
bifunctional phosphoribosylaminoimidazole carboxylase/phosphoribosylaminoimidazole succinocarboxamide synthetase isoform h2 (human)
hPAICS/iso:h2
"A bifunctional phosphoribosylaminoimidazole carboxylase/phosphoribosylaminoimidazole succinocarboxamide synthetase (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P22234-2." [PRO:DNx, UniProtKB:P22234]

organism-modification


PR:000048686
bifunctional phosphoribosylaminoimidazole carboxylase/phosphoribosylaminoimidazole succinocarboxamide synthetase, initiator methionine removed form (human)
hPAICS/InitMet-
"A bifunctional phosphoribosylaminoimidazole carboxylase/phosphoribosylaminoimidazole succinocarboxamide synthetase (human) that has had the initiator methionine removed. UniProtKB:P22234, 2-425." [PRO:DNx, Reactome:R-HSA-62502]

organism-modification


PR:000068081
bifunctional phosphoribosylaminoimidazole carboxylase/phosphoribosylaminoimidazole succinocarboxamide synthetase phosphorylated 1 (human)
hPAICS/Phos:1
"A bifunctional phosphoribosylaminoimidazole carboxylase/phosphoribosylaminoimidazole succinocarboxamide synthetase (human) that has been phosphorylated on the residue at the position equivalent to Ser-27 of the amino acid sequence represented by UniProtKB:P22234-1. Example: UniProtKB:P22234-1, Ser-27, MOD:00046." [IEDB_epitope:633891, PRO:DNx]

organism-modification


PR:000069262
bifunctional phosphoribosylaminoimidazole carboxylase/phosphoribosylaminoimidazole succinocarboxamide synthetase methylated 1 (human)
hPAICS/Me:1
"A bifunctional phosphoribosylaminoimidazole carboxylase/phosphoribosylaminoimidazole succinocarboxamide synthetase (human) that has been methylated on the residue at the position equivalent to Glu-127 of the amino acid sequence represented by UniProtKB:P22234-1. Example: UniProtKB:P22234-1, Glu-127, MOD:00713." [IEDB_epitope:1317244, PRO:DNx]

organism-modification


PR:000069437
bifunctional phosphoribosylaminoimidazole carboxylase/phosphoribosylaminoimidazole succinocarboxamide synthetase deaminated 1 (human)
hPAICS/Deam:1
"A bifunctional phosphoribosylaminoimidazole carboxylase/phosphoribosylaminoimidazole succinocarboxamide synthetase (human) that has been deaminated on the residue at the position equivalent to Asn-395 of the amino acid sequence represented by UniProtKB:P22234-1. Example: UniProtKB:P22234-1, Asn-395, MOD:00684." [IEDB_epitope:1764741, IEDB_epitope:893261, PRO:DNx]

organism-modification


PR:000069657
bifunctional phosphoribosylaminoimidazole carboxylase/phosphoribosylaminoimidazole succinocarboxamide synthetase methylated 2 (human)
hPAICS/Me:2
"A bifunctional phosphoribosylaminoimidazole carboxylase/phosphoribosylaminoimidazole succinocarboxamide synthetase (human) that has been methylated on the residue at the position equivalent to Cys-266 of the amino acid sequence represented by UniProtKB:P22234-1. Example: UniProtKB:P22234-1, Cys-266, MOD:00660." [IEDB_epitope:1008453, IEDB_epitope:1048524, PRO:DNx]

organism-modification


PR:000072456
bifunctional phosphoribosylaminoimidazole carboxylase/phosphoribosylaminoimidazole succinocarboxamide synthetase cysteinylated 1 (human)
hPAICS/Cyst:1
"A bifunctional phosphoribosylaminoimidazole carboxylase/phosphoribosylaminoimidazole succinocarboxamide synthetase (human) that has been cysteinylated on the residue at the position equivalent to Cys-266 of the amino acid sequence represented by UniProtKB:P22234-1. Example: UniProtKB:P22234-1, Cys-266, MOD:00765." [IEDB_epitope:1048523, PRO:DNx]

organism-modification


PR:000081686
bifunctional phosphoribosylaminoimidazole carboxylase/phosphoribosylaminoimidazole succinocarboxamide synthetase cysteinylated 2 (human)
hPAICS/Cyst:2
"A bifunctional phosphoribosylaminoimidazole carboxylase/phosphoribosylaminoimidazole succinocarboxamide synthetase (human) that has been cysteinylated on the residue at the position equivalent to Cys-281 of the amino acid sequence represented by UniProtKB:P22234-1. Example: UniProtKB:P22234-1, Cys-281, MOD:00765." [IEDB_epitope:1308320, PRO:DNx]

organism-modification


PR:000081926
bifunctional phosphoribosylaminoimidazole carboxylase/phosphoribosylaminoimidazole succinocarboxamide synthetase cysteinylated 3 (human)
hPAICS/Cyst:3
"A bifunctional phosphoribosylaminoimidazole carboxylase/phosphoribosylaminoimidazole succinocarboxamide synthetase (human) that has been cysteinylated on the residue at the position equivalent to Cys-63 of the amino acid sequence represented by UniProtKB:P22234-1. Example: UniProtKB:P22234-1, Cys-63, MOD:00765." [IEDB_epitope:1024375, PRO:DNx]

organism-modification


PR:000082625
bifunctional phosphoribosylaminoimidazole carboxylase/phosphoribosylaminoimidazole succinocarboxamide synthetase methylated 3 (human)
hPAICS/Me:3
"A bifunctional phosphoribosylaminoimidazole carboxylase/phosphoribosylaminoimidazole succinocarboxamide synthetase (human) that has been methylated on the residue at the position equivalent to Cys-295 of the amino acid sequence represented by UniProtKB:P22234-1. Example: UniProtKB:P22234-1, Cys-295, MOD:00660." [IEDB_epitope:1021476, PRO:DNx]

organism-modification


PR:000083347
bifunctional phosphoribosylaminoimidazole carboxylase/phosphoribosylaminoimidazole succinocarboxamide synthetase methylated 4 (human)
hPAICS/Me:4
"A bifunctional phosphoribosylaminoimidazole carboxylase/phosphoribosylaminoimidazole succinocarboxamide synthetase (human) that has been methylated on the residue at the position equivalent to Cys-91 of the amino acid sequence represented by UniProtKB:P22234-1. Example: UniProtKB:P22234-1, Cys-91, MOD:00660." [IEDB_epitope:1011885, PRO:DNx]

organism-modification


PR:000083612
bifunctional phosphoribosylaminoimidazole carboxylase/phosphoribosylaminoimidazole succinocarboxamide synthetase deaminated 2 (human)
hPAICS/Deam:2
"A bifunctional phosphoribosylaminoimidazole carboxylase/phosphoribosylaminoimidazole succinocarboxamide synthetase (human) that has been deaminated on the residue at the position equivalent to Gln-389 of the amino acid sequence represented by UniProtKB:P22234-1. Example: UniProtKB:P22234-1, Gln-389, MOD:00685." [IEDB_epitope:1717191, PRO:DNx]

organism-modification


PR:000084634
bifunctional phosphoribosylaminoimidazole carboxylase/phosphoribosylaminoimidazole succinocarboxamide synthetase cysteinylated 4 (human)
hPAICS/Cyst:4
"A bifunctional phosphoribosylaminoimidazole carboxylase/phosphoribosylaminoimidazole succinocarboxamide synthetase (human) that has been cysteinylated on the residue at the position equivalent to Cys-100 of the amino acid sequence represented by UniProtKB:P22234-1. Example: UniProtKB:P22234-1, Cys-100, MOD:00765." [IEDB_epitope:1575290, PRO:DNx]

organism-gene


PR:P38024
multifunctional protein ADE2 (chicken)
chick-PAICS
"A bifunctional phosphoribosylaminoimidazole carboxylase/phosphoribosylaminoimidazole succinocarboxamide synthetase that is encoded in the genome of chicken." [PRO:DNx]

organism-gene


PR:P51583
bifunctional phosphoribosylaminoimidazole carboxylase/phosphoribosylaminoimidazole succinocarboxamide synthetase (rat)
rPAICS
"A bifunctional phosphoribosylaminoimidazole carboxylase/phosphoribosylaminoimidazole succinocarboxamide synthetase that is encoded in the genome of rat." [PANTHER:PTHR11609:SF2, PRO:DNx]

organism-sequence


PR:P51583-1
bifunctional phosphoribosylaminoimidazole carboxylase/phosphoribosylaminoimidazole succinocarboxamide synthetase isoform 1 (rat)
rPAICS/iso:1
"A bifunctional phosphoribosylaminoimidazole carboxylase/phosphoribosylaminoimidazole succinocarboxamide synthetase isoform 1 that is encoded in the genome of rat." [PRO:DNx]

organism-gene


PR:Q10457
probable multifunctional protein ADE2 (worm)
PAICS (worm)
"A bifunctional phosphoribosylaminoimidazole carboxylase/phosphoribosylaminoimidazole succinocarboxamide synthetase that is encoded in the genome of worm." [OMA:Q10457, PRO:DNx]

organism-gene


PR:Q9DCL9
bifunctional phosphoribosylaminoimidazole carboxylase/phosphoribosylaminoimidazole succinocarboxamide synthetase (mouse)
mPAICS
"A bifunctional phosphoribosylaminoimidazole carboxylase/phosphoribosylaminoimidazole succinocarboxamide synthetase that is encoded in the genome of mouse." [OMA:Q9DCL9, PRO:DNx]

organism-sequence


PR:Q9DCL9-1
bifunctional phosphoribosylaminoimidazole carboxylase/phosphoribosylaminoimidazole succinocarboxamide synthetase isoform 1 (mouse)
mPAICS/iso:1
"A bifunctional phosphoribosylaminoimidazole carboxylase/phosphoribosylaminoimidazole succinocarboxamide synthetase isoform 1 that is encoded in the genome of mouse." [PRO:DNx]

organism-gene


PR:Q9I7S8
bifunctional phosphoribosylaminoimidazole carboxylase/phosphoribosylaminoimidazole succinocarboxamide synthetase (fruit fly)
fly-PAICS
"A bifunctional phosphoribosylaminoimidazole carboxylase/phosphoribosylaminoimidazole succinocarboxamide synthetase that is encoded in the genome of fruit fly." [OMA:Q9I7S8, PRO:DNx]

sequence


PR:000039065
bifunctional phosphoribosylaminoimidazole carboxylase/phosphoribosylaminoimidazole succinocarboxamide synthetase isoform 1
PAICS/iso:1
"A bifunctional phosphoribosylaminoimidazole carboxylase/phosphoribosylaminoimidazole succinocarboxamide synthetase that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P22234-1 or a 1:1 ortholog thereof." [PRO:DNx]

organism-sequence


PR:P22234-1
bifunctional phosphoribosylaminoimidazole carboxylase/phosphoribosylaminoimidazole succinocarboxamide synthetase isoform 1 (human)
hPAICS/iso:1
"A bifunctional phosphoribosylaminoimidazole carboxylase/phosphoribosylaminoimidazole succinocarboxamide synthetase isoform 1 that is encoded in the genome of human." [PRO:DNx]

organism-sequence


PR:P51583-1
bifunctional phosphoribosylaminoimidazole carboxylase/phosphoribosylaminoimidazole succinocarboxamide synthetase isoform 1 (rat)
rPAICS/iso:1
"A bifunctional phosphoribosylaminoimidazole carboxylase/phosphoribosylaminoimidazole succinocarboxamide synthetase isoform 1 that is encoded in the genome of rat." [PRO:DNx]

organism-sequence


PR:Q9DCL9-1
bifunctional phosphoribosylaminoimidazole carboxylase/phosphoribosylaminoimidazole succinocarboxamide synthetase isoform 1 (mouse)
mPAICS/iso:1
"A bifunctional phosphoribosylaminoimidazole carboxylase/phosphoribosylaminoimidazole succinocarboxamide synthetase isoform 1 that is encoded in the genome of mouse." [PRO:DNx]

modification


PR:000020864
bifunctional phosphoribosylaminoimidazole carboxylase/phosphoribosylaminoimidazole succinocarboxamide synthetase, initiator methionine removed form
PAICS/InitMet-
"A bifunctional phosphoribosylaminoimidazole carboxylase/phosphoribosylaminoimidazole succinocarboxamide synthetase that has had the initiator methionine removed." [PRO:DNx]

organism-modification


PR:000048686
bifunctional phosphoribosylaminoimidazole carboxylase/phosphoribosylaminoimidazole succinocarboxamide synthetase, initiator methionine removed form (human)
hPAICS/InitMet-
"A bifunctional phosphoribosylaminoimidazole carboxylase/phosphoribosylaminoimidazole succinocarboxamide synthetase (human) that has had the initiator methionine removed. UniProtKB:P22234, 2-425." [PRO:DNx, Reactome:R-HSA-62502]