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Protein Ontology report - proprotein convertase subtilisin/kexin type 6
PR:000012438 - http://purl.obolibrary.org/obo/PR_000012438
 
  Protein Forms      
Ontology Information Show OBO stanza
  PRO ID
PR:000012438   
  PRO nameproprotein convertase subtilisin/kexin type 6 
  Synonyms
PRO-Short-label: EXACT:PCSK6
Gene-based: RELATED:PACE4
Other: EXACT:paired basic amino acid cleaving enzyme 4 | SPC4 | subtilisin-like proprotein convertase 4 | subtilisin/kexin-like protease PACE4
  Definition"A subtilisin/kexin-type proprotein convertase that is a translation product of the human PCSK6 gene or a 1:1 ortholog thereof." [PRO:DNx] 
  PRO Categorygene 
  ParentPR:000003136 subtilisin/kexin-type proprotein convertase
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Gene1                                                  Organism-Gene 2                                        
         Sequence0                                                  Organism-Sequence 8                                        
         Modification1                                                  Organism-Modification 2                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Related Cross References

  Db identifiers
IUPHARobj:2386
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Protein Forms Switch to Compact View   

Category  

PRO ID

Name

Short Name

Definition

Ann. Has Annotation?

Comp. In Complex?
gene



PR:000012438

proprotein convertase subtilisin/kexin type 6

PCSK6


"A subtilisin/kexin-type proprotein convertase that is a translation product of the human PCSK6 gene or a 1:1 ortholog thereof." [PRO:DNx]


organism-gene



PR:P29122

proprotein convertase subtilisin/kexin type 6 (human)

hPCSK6


"A proprotein convertase subtilisin/kexin type 6 that is encoded in the genome of human." [PRO:DNx, UniProtKB:P29122]


organism-sequence



PR:P29122-1

proprotein convertase subtilisin/kexin type 6 isoform hPACE4A-I (human)

hPCSK6/iso:hPACE4A-I


"A proprotein convertase subtilisin/kexin type 6 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P29122-1." [PRO:DNx, UniProtKB:P29122]


organism-sequence



PR:P29122-2

proprotein convertase subtilisin/kexin type 6 isoform hPACE4A-II (human)

hPCSK6/iso:hPACE4A-II


"A proprotein convertase subtilisin/kexin type 6 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P29122-2." [PRO:DNx, UniProtKB:P29122]


organism-sequence



PR:P29122-3

proprotein convertase subtilisin/kexin type 6 isoform hPACE4B (human)

hPCSK6/iso:hPACE4B


"A proprotein convertase subtilisin/kexin type 6 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P29122-3." [PRO:DNx, UniProtKB:P29122]


organism-sequence



PR:P29122-4

proprotein convertase subtilisin/kexin type 6 isoform hPACE4C (human)

hPCSK6/iso:hPACE4C


"A proprotein convertase subtilisin/kexin type 6 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P29122-4." [PRO:DNx, UniProtKB:P29122]


organism-sequence



PR:P29122-5

proprotein convertase subtilisin/kexin type 6 isoform hPACE4CS (human)

hPCSK6/iso:hPACE4CS


"A proprotein convertase subtilisin/kexin type 6 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P29122-5." [PRO:DNx, UniProtKB:P29122]


organism-sequence



PR:P29122-6

proprotein convertase subtilisin/kexin type 6 isoform hPACE4D (human)

hPCSK6/iso:hPACE4D


"A proprotein convertase subtilisin/kexin type 6 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P29122-6." [PRO:DNx, UniProtKB:P29122]


organism-sequence



PR:P29122-7

proprotein convertase subtilisin/kexin type 6 isoform hPACE4E-I (human)

hPCSK6/iso:hPACE4E-I


"A proprotein convertase subtilisin/kexin type 6 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P29122-7." [PRO:DNx, UniProtKB:P29122]


organism-sequence



PR:P29122-8

proprotein convertase subtilisin/kexin type 6 isoform hPACE4E-II (human)

hPCSK6/iso:hPACE4E-II


"A proprotein convertase subtilisin/kexin type 6 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P29122-8." [PRO:DNx, UniProtKB:P29122]


organism-modification



PR:000056328

proprotein convertase subtilisin/kexin type 6 O-glycosylated 1 (human)

hPCSK6/OGlyco:1


"A proprotein convertase subtilisin/kexin type 6 (human) that has been O-glycosylated at the residue equivalent to Thr-683 of the amino acid sequence represented by UniProtKB:P29122-1, in which the glycan composition is represented by GlyTouCan:G43417UB. Example: UniProtKB:P29122-1, Thr-683, MOD:00005~GNO:G43417UB." [GlyGen:P29122-1, PMID:30459171, PRO:DNx]


organism-modification



PR:000075312

proprotein convertase subtilisin/kexin type 6, mature form (human)

hPCSK6/mature


"A proprotein convertase subtilisin/kexin type 6 (human) that has had the signal peptide and propeptide removed. Example: UniProtKB:P29122-1, 150-969." [PRO:DNx, Reactome:R-HSA-1181107, Reactome:R-HSA-3009047, Reactome:R-HSA-8849792]


organism-gene



PR:Q63415

proprotein convertase subtilisin/kexin type 6 (rat)

rPCSK6


"A proprotein convertase subtilisin/kexin type 6 that is encoded in the genome of rat." [OMA:Q63415, PRO:DNx]


modification



PR:000020889

proprotein convertase subtilisin/kexin type 6 proteolytic cleavage product

PCSK6/ClvPrd


"A proprotein convertase subtilisin/kexin type 6 that has been processed by proteolytic cleavage." [PRO:DNx]